Simultaneous coexpression of memory-related and effector-related genes by individual human CD8 T cells depends on antigen specificity and differentiation

Journal of Immunotherapy

Volumn 35, Issue 6, 2012, Pages 488-501

  Gupta, Bhawna ^a   Iancu, Emanuela M ^a   Gannon, Philippe O ^a   Wieckowski, Sébastien ^a   Baitsch, Lukas ^b   Speiser, Daniel E ^b   Rufer, Nathalie ^a,b  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

CD8 T cells; effector; gene expression; human; melanoma; memory; single cell; TCR clonotype; vaccination; virus

Indexed keywords

CD27 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; INTERLEUKIN 7 RECEPTOR; MELAN A;

ANTIGEN SPECIFICITY; ARTICLE; CANCER IMMUNIZATION; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; EFFECTOR CELL; EX VIVO STUDY; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; MELANOMA; PRIORITY JOURNAL;

ANTIGENS, CD27; CANCER VACCINES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; EPITOPES; GENE EXPRESSION PROFILING; GRANZYMES; HLA-A2 ANTIGEN; HUMANS; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; MART-1 ANTIGEN; MELANOMA; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY D; PORE FORMING CYTOTOXIC PROTEINS; RECEPTORS, CCR5; RECEPTORS, CXCR3; RECEPTORS, INTERLEUKIN-7; T-BOX DOMAIN PROTEINS; VACCINES, SUBUNIT;

EID: 84864196837     PISSN: 15249557     EISSN: 15374513     Source Type: Journal    
DOI: 10.1097/CJI.0b013e31826183a7     Document Type: Article

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