Direct Monitoring of the Strand Passage Reaction of DNA Topoisomerase II Triggers Checkpoint Activation

PLoS Genetics

Volumn 9, Issue 10, 2013, Pages

  Furniss, Katherine L ^a   Tsai, Hung Ji ^a   Byl, Jo Ann W ^b   Lane, Andrew B ^a   Vas, Amit C ^a   Hsu, Wei Shan ^a   Osheroff, Neil ^b   Clarke, Duncan J ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); FUNGAL PROTEIN; PLASMID DNA; PROTEIN TOP2 B44; UNCLASSIFIED DRUG;

ANAPHASE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CENTROMERE; CHROMOSOME CONDENSATION; CHROMOSOME SEGREGATION; CHROMOSOME STRUCTURE; CONTROLLED STUDY; DNA CLEAVAGE; DNA DAMAGE; DNA DETERMINATION; DNA REPLICATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FUNGAL STRAIN; GENE FREQUENCY; HYDROLYSIS; MITOSIS; NONHUMAN; PLASMID; PROMOTER REGION; PROTEIN CLEAVAGE; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE; YEAST;

CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CHECKPOINT KINASE 2; CHROMOSOME SEGREGATION; DNA; DNA TOPOISOMERASES, TYPE II; HUMANS; KINETOCHORES; MAD2 PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84887268157     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003832     Document Type: Article

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