Human DNA topoisomerases IIα and IIβ can functionally substitute for yeast TOP2 in chromosome segregation and recombination

Molecular and General Genetics

Volumn 252, Issue 1-2, 1996, Pages 79-86

  Jensen, Sanne ^a   Redwood, Charles S ^b   Jenkins, John R ^b,c   Andersen, Anni H ^a   Hickson, Ian D ^b  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Chromosome segregation; Genetic recombination; Topoisomerases

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); FUNGAL PROTEIN; ISOENZYME; RIBOSOME DNA;

ARTICLE; CHROMOSOME SEGREGATION; CONTROLLED STUDY; ENZYME ACTIVITY; FUNGUS GROWTH; FUNGUS MUTANT; GENE CLUSTER; GENE DISRUPTION; GENETIC RECOMBINATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SPOROGENESIS;

FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0029905883     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02173207     Document Type: Article

References (36)

1. Adachi N, Miyaike M, Ikeda H, Kikuchi A (1992) Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation. Nucleic Acids Res 20:5297-5303
2. Austin CA, Marsh KL, Wasserman RA, Willmore E, Sayer PJ, Wang JC, Fisher LM (1995) Expression, domain structure, and enzymatic properties of an active recombinant human DNA topoisomerase IIβ. J Biol Chem 270:15739-15746
3. Brill SJ, Sternglanz R (1988) Transcription-dependent DNA supercoiling in yeast DNA topoisomerase mutants. Cell 54:403-411
4. Christman MF, Dietrich FS, Fink GR (1988) Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. Cell 55:413-425
5. DiNardo S, Voelkel K, Sternglanz R (1984) DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication. Proc Natl Acad Sci USA 81:2616-2620
6. Drake FH, Zimmerman JP, McCabe FL, Bartus HF, Per SR, Sullivan DM, Ross WE, Mattern MR, Johnson RK, Crooke ST, Mirabelli CK (1987) Purification of topoisomerase II from amsacrine-resistant P388 leukemia cells: evidence for two forms of the enzyme. J Biol Chem 262:16739-16747
7. Drake FH, Hofmann GA, Bartus HF, Mattern MR, Crooke ST, Mirabelli CK (1989) Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II. Biochemistry 28:8154-8160
8. Droge P (1994) Protein tracking-induced supercoiling of DNA: a tool to regulate DNA transactions in vivo? BioEssays 16:91-99
9. Goto T, Wang JC (1984) Yeast DNA topoisomerase II is encoded by a single-copy, essential gene. Cell 36:1073-1080
10. Holm C, Goto T, Wang JC, Botstein D (1985) DNA topoisomerase II is required at the time of mitosis in yeast. Cell 41:553-563
11. Jenkins JR, Ayton P, Jones T, Davies SL, Simmons DL, Harris AL, Sheer D, Hickson ID (1992) Isolation of cDNA clones encoding the β isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24. Nucleic Acids Res 20: 5587-5592
12. Kim RA, Wang JC (1989a) A subthreshold level of DNA topoisomerases leads to the excision of yeast rDNA as extrachromosomal rings. Cell 57:975-985
13. Kim RA, Wang JC (1989a) Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae. J Mol Biol 208:257-267
14. Kroll DJ, Sullivan DM, Gutierrez-Hartmann A, Hoeffler JP (1993) Modification of DNA topoisomerase II activity via direct interactions with the cyclic adenosine-3′, 5′-monophosphate response element-binding protein and related transcription factors. Mol Endocrmol 7:305-318
15. Ma X, Saitoh N, Curtis PJ (1993) Purification and characterisation of a nuclear DNA-binding factor complex containing topoisomerase II and chromosome scaffold protein 2. J Biol Chem 268:6182-6188
16. Osheroff N (1989) Biochemical basis for the interactions of type I and type II topoisomerase with DNA. Pharmacol Ther 41:223-241
17. Petrov P, Drake FH, Loranger A, Huang W, Hancock R (1993) Localisation of DNA topoisomerase II in Chinese hamster fibroblasts by confocal and electron microscopy. Exp Cell Res 204:73-81
18. Rose D, Holm C (1993) Meiosis-specific arrest revealed in DNA topoisomerase II mutants. Mol Cell Biol 13:3445-3455
19. Rose D, Thomas W, Holm C (1990) Segregation of recombined chromosomes in meiosis I requires DNA topoisomerase II. Cell 60:1009-1017
20. Schiestl RH, Gietz RD (1989) High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr Genet 16:339-346
21. Sikorski RS, Hieter P (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiea. Genetics 122:19-27
22. Snapka RM, Powelson MA, Strayer JM (1988) Swiveling and decatenation of replicating simian virus 40 genomes in vivo. Mol Cell Biol 8:515-521
23. Sternglanz R (1989) DNA topoisomerases. Curr Opin Cell Biol 1:533-535
24. Tan KB, Dorman TE, Falls KM, Chung TDU, Mirabelli CK, Crooke ST, Mao J-I (1992) Topoisomerase IIα and topoisomerase IIβ genes: characterization and mapping to human chromosomes 17 and 3, respectively. Cancer Res 52:231-234
25. Thrash C, Bankier AT, Barrell BG, Sternglanz R (1985) Cloning, characterisation and sequence of the yeast topoisomecse I gene. Proc Natl Acad Sci USA 82:4374-4378
26. Tsai-Pflugfelder MT, Liu LF, Liu AA, Tewey KM, Whong-Peng J, Knutsen T, Huebner K, Croce CM, Wang JC (1988) Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localisation of the gene to chromosome 17q21-21. Proc Natl Acad Sci USA 85:7177-7181
27. Uemura T, Yanagida M (1984) Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phonotypes in cell growth and chromatin organization. EMBO J 3:1737-1744
28. Uemura T, Morikawa K, Yanagida M (1986) The nucleotide sequence of the fission yeast DNA topoisomerase II gene: structural and functional relationship to other DNA topoisomerases. EMBO J 5:2355-2361
29. Wang JC (1985) DNA topoisomerases. Annu Rev Biochem 54: 665-697
30. Wang JC, Caron PR, Kim RA (1990) The role of DNA topoisomerases in recombination and genome stability: a double edged sword? Cell 62:403-406
31. Wasserman RA, Austin CA, Fisher LM, Wang JC (1993) Use of yeast in the study of anticancer targeting DNA topoisomerases: expression of a functional recombinant human DNA topoisomerase IIa in yeast. Cancer Res 53:3591-3596
32. Watt PM, Hickson ID (1994) Structure and function of type II DNA topoisomerases. Biochem J 303:681-695
33. Watt PM, Louis EJ, Borts RH, Hickson ID (1995) Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell 81:253-260
34. Woessner RD, Mattern MR, Mirabelli CK, Johnson RK, Drake FH (1991) Proliferation- and cell cycle-dependent differences in expression of the 170 kDa and 180 kDa forms of topoisomerase II in NIH-3T3 cells. Cell Growth and Differ 2:209-214
35. Yang L, Wold MS, Li JJ, Kelly TJ, Liu LF (1987) Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro. Proc Natl Acad Sci USA 84:950-954
36. Zini N, Martelli AM, Sabatelli P, Santi S, Negri C, Astaldi-Ricotti GCB, Maraldi NM (1992) The 180 kDa isoform of topoisomerase II is localized in the nucleolus and belongs to the structural elements for the nucleolar remnant. Exp Cell Res 200:460-466