Topoisomerase IIα maintains genomic stability through decatenation G 2 checkpoint signaling

Oncogene

Volumn 29, Issue 34, 2010, Pages 4787-4799

  Bower, J J ^a,b   Karaca, G F ^a   Zhou, Y ^a   Simpson, D A ^a   Cordeiro Stone, M ^a,b   Kaufmann, W K ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

chromosomal instability; decatenation; G2 checkpoint; topoisomerase IIa; topoisomerase IIb

Indexed keywords

2,3 BIS(3,5 DIOXO 1 PIPERAZINYL)BUTANE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE 2ALPHA; DNA TOPOISOMERASE 2BETA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; DNA; DNA BINDING PROTEIN; DNA TOPOISOMERASE II ALPHA; PIPERAZINE DERIVATIVE; TUMOR ANTIGEN;

ALLELE; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL FUNCTION; CHROMOSOME SEGREGATION; DIPLOIDY; FIBROBLAST; FLOW CYTOMETRY; GENE LOCUS; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INTERPHASE; MITOSIS; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; BIOSYNTHESIS; CELL CYCLE; CHROMATID; CYTOLOGY; DOUBLE STRANDED DNA BREAK; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

MAMMALIA;

ANTIGENS, NEOPLASM; CELL CYCLE; CELL CYCLE PROTEINS; CHROMATIDS; CHROMOSOME SEGREGATION; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA TOPOISOMERASES, TYPE II, EUKARYOTIC; DNA-BINDING PROTEINS; FIBROBLASTS; G2 PHASE; GENES, P16; GENOMIC INSTABILITY; HUMANS; MITOSIS; PIPERAZINES; SIGNAL TRANSDUCTION;

EID: 77956172250     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.232     Document Type: Article

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