Involvement of insulin-degrading enzyme in insulin-and atrial natriuretic peptide-sensitive internalization of amyloid-β peptide in mouse brain capillary endothelial cells

Journal of Alzheimer's Disease

Volumn 38, Issue 1, 2014, Pages 185-200

  Ito, Shingo ^a,b,c   Ohtsuki, Sumio ^a,b,c   Murata, Sho ^a   Katsukura, Yuki ^a,b   Suzuki, Hiroya ^a   Funaki, Miho ^a   Tachikawa, Masanori ^a   Terasaki, Tetsuya ^a,b  

^a TOHOKU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Alzheimer's disease; amyloid peptide; atrial natriuretic peptide; blood brain barrier; brain capillary endothelial cells; insulin degrading enzyme

Indexed keywords

1,10 PHENANTHROLINE; AMYLOID BETA PROTEIN[1-40]; ATRIAL NATRIURETIC FACTOR; BACITRACIN; INSULINASE; IODINE 125; N ETHYLMALEIMIDE; NATRIURETIC PEPTIDE RECEPTOR C; PHOSPHORAMIDON; THIORPHAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN CAPILLARY ENDOTHELIAL CELL; CELL MEMBRANE; CONTROLLED STUDY; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; MALE; MICROINJECTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALZHEIMER'S DISEASE; AMYLOID-Β PEPTIDE; ATRIAL NATRIURETIC PEPTIDE; BLOOD-BRAIN BARRIER; BRAIN CAPILLARY ENDOTHELIAL CELLS; INSULIN-DEGRADING ENZYME;

AMYLOID BETA-PEPTIDES; ANIMALS; ATRIAL NATRIURETIC FACTOR; BLOOD-BRAIN BARRIER; BRAIN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; INSULIN; INSULYSIN; MALE; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; RECEPTORS, ATRIAL NATRIURETIC FACTOR; RNA, SMALL INTERFERING; TIME FACTORS;

EID: 84887232799     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-122077     Document Type: Article

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