The low density lipoprotein receptor-related protein 1 mediates uptake of amyloid β peptides in an in vitro model of the blood-brain barrier cells

Journal of Biological Chemistry

Volumn 283, Issue 50, 2008, Pages 34554-34562

  Yamada, Kaoru ^a   Hashimoto, Tadafumi ^a,b   Yabuki, Chiori ^a   Nagae, Yusuke ^a   Tachikawa, Masanori ^c   Strickland, Dudley K ^d   Liu, Qiang ^e   Bu, Guojun ^e   Basak, Jacob M ^e   Holtzman, David M ^e   Ohtsuki, Sumio ^c   Terasaki, Tetsuya ^c   Iwatsubo, Takeshi ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; ENDOTHELIAL CELLS; GLYCOPROTEINS; LIPOPROTEINS; PEPTIDES;

AMYLOID-BETA PEPTIDES; ENDOTHELIAL CELL LINE; LOW DENSITY LIPOPROTEIN RECEPTORS; MOUSE EMBRYONIC FIBROBLASTS; NEUTRALIZING ANTIBODIES; RECEPTOR-ASSOCIATED PROTEINS; SMALL INTERFERENCE RNA; TISSUE PLASMINOGEN ACTIVATOR;

BLOOD;

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; NEUTRALIZING ANTIBODY; SMALL INTERFERING RNA; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; ENDOCYTOSIS; ENDOTHELIUM CELL; EXPERIMENTAL MODEL; FIBROBLAST; HUMAN; HUMAN CELL; IMMOBILIZED CELL; IN VITRO STUDY; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN SECRETION; PROTEIN TRANSPORT; RAT;

RATTUS;

EID: 58049199498     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801487200     Document Type: Article

References (55)

1. Selkoe, D. J. (2001) Physiol. Rev. 81, 741-766
2. Goate, A., Chartier-Harlin, M. C., Mullan, M., Brown, J., Crawford, F., Fidani, L., Giuffra, L., Haynes, A., Irving, N., James, L., Mant, R., Newton, P., Rooke, K., Rogues, P., Talbot, C., Pericak-Vance, M., Roses, A., Williamson, R., Rossor, M., Owen, M., and Hardy, J. (1991) Nature 349, 704-706
3. Mullan, M., Crawford, F., Axelman, K., Houlden, H., Lilius, L., Winblad, B., and Lannfelt, L. (1992) Nat. Genet. 1, 345-347
4. Rovelet-Lecrux, A., Hannequin, D., Raux, G., Le Meur, N., Laquerrière, A., Vital, A., Dumanchin, C., Feuillette, S., Brice, A., Vercelletto, M., Dubas, F., Frebourg, T., and Campion, D. (2006) Nat. Genet. 38, 24-26
5. Citron, M., Oltersdorf, T., Haass, C., McConlogue, L., Hung, A. Y., Seubert, P., Vigo-Pelfrey, C., Lieberburg, I., and Selkoe, D. J. (1992) Nature 360, 672-674
6. Suzuki, N., Cheung, T. T., Cai, X. D., Odaka, A., Otvos, L., Jr., Eckman, C., Golde, T. E., and Younkin, S. G. (1994) Science 264, 1336-1340
7. Iwatsubo, T., Odaka, A., Suzuki, N., Mizusawa, H., Nukina, N., and Ihara, Y. (1994) Neuron 13, 45-53
8. Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F., and Cole, G. (1996) Science 274, 99-102
9. Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., and Selkoe, D. J. (2002) Nature 416, 535-539
10. Shankar, G. M., Bloodgood, B. L., Townsend, M., Walsh, D. M., Selkoe, D. J., and Sabatini, B. L. (2007) J. Neurosci. 27, 2866-2875
11. Iwata, N., Tsubuki, S., Takaki, Y., Watanabe, K., Sekiguchi, M., Hosoki, E., Kawashima-Morishima, M., Lee, H. J., Hama, E., Sekine-Aizawa, Y., and Saido, T. C. (2000) Nat. Med. 6, 143-150
12. Qiu, W. Q., Walsh, D. M., Ye, Z., Vekrellis, K., Zhang, J., Podlisny, M. B., Rosner, M. R., Safavi, A., Hersh, L. B., and Selkoe, D. J. (1998) J. Biol. Chem. 273, 32730-32738
13. Paresce, D. M., Ghosh, R. N., and Maxfield, F. R. (1996) Neuron 17, 553-565
14. Wyss-Coray, T., Loike, J. D., Brionne, T. C., Lu, E., Anankov, R., Yan, F., Silverstein, S. C., and Husemann, J. (2003) Nat. Med. 9, 453-457
15. Shibata, M., Yamada, S., Kumar, S. R., Calero, M., Bading, J., Frangione, B., Holtzman, D. M., Miller, C. A., Strickland, D. K., Ghiso, J., and Zlokovic, B. V. (2000) J. Clin. Invest. 106, 1489-1499
16. Shiiki, T., Ohtsuki, S., Kurihara, A., Naganuma, H., Nishimura, K., Tachikawa, M., Hosoya, K., and Terasaki, T. (2004) J. Neurosci. 24, 9632-9637
17. Zlokovic, B. V. (1995) Pharm. Res. 12, 1395-1406
18. Deane, R., Wu, Z., Sagare, A., Davis, J., Yan, S. D., Hamm, K., Xu, F., Parisi, M., LaRue, B., Hu, H. W., Spijkers, P., Guo, H., Song, X., Lenting, P. J., Van Nostrand, W. E., and Zlokovic, B. V. (2004) Neuron 43, 333-344
19. Terasaki, T., and Hosoya, K. (2001) Biol. Pharm. Bull. 24, 111-118
20. Hosoya, K. I., Takashima, T., Tetsuka, K., Nagura, T., Ohtsuki, S., Takanaga, H., Ueda, M., Yanai, N., Obinata, M., and Terasaki, T. (2000) J. Drug Target. 8, 357-370
21. Bu, G., Geuze, H. J., Strous, G. J., and Schwartz, A. L. (1995) EMBO J. 14, 2269-2280
22. Kinoshita, A., Shah, T., Tangredi, M. M., Strickland, D. K., and Hyman, B. T. (2003) J. Biol. Chem. 278, 41182-41188
23. Lee, S. H., Takahashi, M., Honke, K., Miyoshi, E., Osumi, D., Sakiyama, H., Ekuni, A., Wang, X., Inoue, S., Gu, J., Kadomatsu, K., and Taniguchi, N. (2006) J. Biochem. (Tokyo) 139, 391-398
24. Ashcom, J. D., Tiller, S. E., Dickerson, K., Cravens, J. L., Argraves, W. S., and Strickland, D. K. (1990) J. Cell Biol. 110, 1041-1048
25. Qing, G., Ma, L. C., Khorchid, A., Swapna, G. V., Mal, T. K., Takayama, M. M., Xia, B., Phadtare, S., Ke, H., Acton, T., Montelione, G. T., Ikura, M., and Inouye, M. (2004) Nat. Biotechnol. 22, 877-882
26. Herz, J., Goldstein, J. L., Strickland, D. K., Ho, Y. K., and Brown, M. S. (1991) J. Biol. Chem. 266, 21232-21238
27. Mikhailenko, I., Battey, F. D., Migliorini, M., Ruiz, J. F., Argraves, K., Moayeri, M., and Strickland, D. K. (2001) J. Biol. Chem. 276, 39484-39491
28. Morikawa, M., Fryer, J. D., Sullivan, P. M., Christopher, E. A., Wahrle, S. E., DeMattos, R. B., O'Dell, M. A., Fagan, A. M., Lashuel, H. A., Walz, T., Asai, K., and Holtzman, D. M. (2005) Neurobiol. Dis. 19, 66-76
29. Hashimoto, T., Wakabayashi, T., Watanabe, A., Kowa, H., Hosoda, R., Nakamura, A., Kanazawa, I., Arai, T., Takio, K., Mann, D. M., and Iwatsubo, T. (2002) EMBO J. 21, 1524-1534
30. Bitan, G., Lomakin, A., and Teplow, D. B. (2001) J. Biol. Chem. 276, 35176-35184
31. Bitan, G., Kirkitadze, M. D., Lomakin, A., Vollers, S. S., Benedek, G. B., and Teplow, D. B. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 330-335
32. Willnow, T. E., and Herz, J. (1994) J. Cell Sci. 107, 719-726
33. Tanabe, S., Shimohigashi, Y., Nakayama, Y., Makino, T., Fujita, T., Nose, T., Tsujimoto, G., Yokokura, T., Naito, M., Tsuruo, T., and Terasaki, T. (1999) J. Pharmacol. Exp. Ther. 290, 561-568
34. Asami-Odaka, A., Ishibashi, Y., Kikuchi, T., Kitada, C., and Suzuki, N. (1995) Biochemistry 34, 10272-10278
35. Qiu, Z., Strickland, D. K., Hyman, B. T., and Rebeck, G. W. (1999) J. Neurochem. 73, 1393-1398
36. Gylys, K. H., Fein, J. A., Tan, A. M., and Cole, G. M. (2003) J. Neurochem. 84, 1442-1451
37. Narita, M., Holtzman, D. M., Schwartz, A. L., and Bu, G. (1997) J. Neurochem. 69, 1904-1911
38. Kang, D. E., Pietrzik, C. U., Baum, L., Chevallier, N., Merriam, D. E., Kounnas, M. Z., Wagner, S. L., Troncoso, J. C., Kawas, C. H., Katzman, R., and Koo, E. H. (2000) J. Clin. Invest. 106, 1159-1166
39. Bu, G., Maksymovitch, E. A., and Schwartz, A. L. (1993) J. Biol. Chem. 268, 13002-13009
40. Koistinaho, M., Lin, S., Wu, X., Esterman, M., Koger, D., Hanson, J., Higgs, R., Liu, F., Malkani, S., Bales, K. R., and Paul, S. M. (2004) Nat. Med. 10, 719-726
41. Horn, I. R., van den Berg, B. M., van der Meijden, P. Z., Pannekoek, H., and van Zonneveld, A. J. (1997) J. Biol. Chem. 272, 13608-13613
42. Deane, R., Yan, S. D., Submamaryan, R. K., LaRue, B., Jovanovic, S., Hogg, E., Welch, D., Manness, L., Lin, C., Yu, J., Zhu, H., Ghiso, J., Frangione, B., Stern, A., Schmidt, A. M., Armstrong, D. L., Arnold, B., Liliensiek, B., Nawroth, P., Hofman, F., Kindy, M., Stern, D., and Zlokovic, B. (2003) Nat. Med. 9, 907-913
43. Lam, F. C., Liu, R., Lu, P., Shapiro, A. B., Renoir, J. M., Sharom, F. J., and Reiner, P. B. (2001) J. Neurochem. 76, 1121-1128
44. Tokuda, T., Calero, M., Matsubara, E., Vidal, R., Kumar, A., Permanne, B., Zlokovic, B., Smith, J. D., Ladu, M. J., Rostagno, A., Frangione, B., and Ghiso, J. (2000) Biochem. J. 348, 359-365
45. Yazawa, H., Yu, Z. X., Takeda Le, Y., Gong, W., Ferrans, V. J., Oppenheim, J. J., Li, C. C., and Wang, J. M. (2001) FASEB J. 15, 2454-2462
46. Nazer, B., Hong, S., and Selkoe, D. J. (2008) Neurobiol. Dis. 30, 94-102
47. Sagare, A., Deane, R., Bell, R. D., Johnson, B., Hamm, K., Pendu, R., Marky, A., Lenting, P. J., Wu, Z., Zarcone, T., Goate, A., Mayo, K., Perlmutter, D., Coma, M., Zhong, Z., and Zlokovic, B. V. (2007) Nat. Med. 13, 1029-1031
48. Koenigsknecht, J., and Landreth, G. (2004) J. Neurosci. 4, 9838-9846
49. Fryer, J. D., Demattos, R. B., McCormick, L. M., O'Dell, M. A., Spinner, M. L., Bales, K. R., Paul, S. M., Sullivan, P. M., Parsadanian, M., Bu, G., and Holtzman, D. M. (2005) J. Biol. Chem. 280, 25754-25759
50. Ziere, G. J., van der Kaaden, M. E., Vogelezang, C. J., Boers, W., Bihain, B. E., Kuiper, J., Kruijt, J. K., and van Berkel, T. J. (1996) Eur. J. Biochem. 242, 703-711
51. Herz, J., and Strickland, D. K. (2001) J. Clin. Invest. 108, 779-784
52. Nykjaer, A., and Willnow, T. E. (2002) Trends Cell Biol. 12, 273-280
53. Nykjaer, A., Petersen, C. M., Møller, B., Jensen, P. H., Moestrup, S. K., Holtet, T. L., Etzerodt, M., Thøgersen, H. C., Munch, M., Andreasen, P. A., and Gliemann, J. (1992) J. Biol. Chem. 267, 14543-14546
54. Sarafanov, A. G., Ananyeva, N. M., Shima, M., and Saenko, E. L. (2001) J. Biol. Chem. 276, 11970-11979
55. Leveugle, B., Scanameo, A., Ding, W., and Fillit, H. (1994) Neuroreport 5, 1389-1392