MicroRNA expression profile in head and neck cancer: HOX-cluster embedded microRNA-196a and microRNA-10b dysregulation implicated in cell proliferation

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Severino, Patricia ^a   Brüggemann, Holger ^b   Andreghetto, Flavia M ^a   Camps, Carme ^c   Klingbeil, Maria de Fatima G ^d   de Pereira, Welbert O ^a   Soares, Renata M ^a   Moyses, Raquel ^e   Wünsch Filho, Victor ^e   Mathor, Monica B ^d   Nunes, Fabio D ^e   Ragoussis, Jiannis ^b   Tajara, Eloiza H ^f  

^a HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

^b AARHUS UNIVERSITY   (Denmark)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES   (Brazil)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

^f Institute of Biomedicine   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 10B; MICRORNA 17 92; MICRORNA 196A; MICRORNA 196B; MICRORNA 34; PROTEIN P53; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CARCINOMA CELL; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELLULAR PARAMETERS; CLINICAL ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; EMBEDDING; FEMALE; GENE CLUSTER; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC DISORDER; HEAD AND NECK CANCER; HOX GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; MALE; MOUTH SQUAMOUS CELL CARCINOMA; NUCLEOTIDE SEQUENCE; PROTEIN RNA BINDING; UPREGULATION;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HEAD AND NECK NEOPLASMS; HOMEODOMAIN PROTEINS; HUMANS; MALE; MICRORNAS; MIDDLE AGED; MOUTH NEOPLASMS; MULTIGENE FAMILY; NEOPLASM GRADING; NEOPLASM STAGING; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; TRANSCRIPTOME; TUMOR MARKERS, BIOLOGICAL;

EID: 84887121683     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-533     Document Type: Article

References (57)

1. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116(2):281-297. 10.1016/S0092-8674(04)00045-5, 14744438.
2. Jopling CL, Yi M, Lancaster AM, Lemon SM, Sarnow P. Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 2005, 309(5740):1577-1581. 10.1126/science.1113329, 16141076.
3. Vasudevan S, Tong YC, Steitz JA. Switching from repression to activation: MicroRNAs can up-regulate translation. Science 2007, 318(5858):1931-1934. 10.1126/science.1149460, 18048652.
4. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebet BL, Mak RH, Ferrando AA, et al. MicroRNA expression profiles classify human cancers. Nature 2005, 435(7043):834-838. 10.1038/nature03702, 15944708.
5. Michael MZ, O'Connor SM, Pellekaan NGV, Young GP, James RJ. Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res 2003, 1(12):882-891.
6. Bartels CL, Tsongalis GJ. MicroRNAs: novel biomarkers for human cancer. Clin Chem 2009, 55(4):623-631. 10.1373/clinchem.2008.112805, 19246618.
7. Forastiere A, Koch W, Trotti A, Sidransky D. Head and neck cancer. N Engl J Med 2001, 345(26):1890-1900. 10.1056/NEJMra001375, 11756581.
8. Mao L, Hong WK, Papadimitrakopoulou VA. Focus on head and neck cancer. Cancer Cell 2004, 5(4):311-316. 10.1016/S1535-6108(04)00090-X, 15093538.
9. Liu X, Chen Z, Yu J, Xia J, Zhou X. MicroRNA profiling and head and neck cancer. Comp Funct Genet 2009, 837514.
10. Babu JM, Prathibha R, Jijith VS, Hariharan R, Pillai MR. A miR-centric view of head and neck cancers. Biochim Biophys Acta 2011, 1816(1):67-72.
11. Wua BH, Xiong XP, Jia J, Zhang WF. MicroRNAs: New actors in the oral cancer scene. Oral Oncol 2011, 47(5):314-319. 10.1016/j.oraloncology.2011.03.019, 21474366.
12. Childs G, Fazzari M, Kung G, Kawachi N, Brandwein-Gensler M, McLemore M, Chen Q, Burk RD, Smith RV, Prystowsky MB, et al. Low-level expression of microRNAs let-7d and miR-205 are prognostic markers of head and neck squamous cell carcinoma. Am J Pathol 2009, 174(3):736-745. 10.2353/ajpath.2009.080731, 2665736, 19179615.
13. Avissar M, McClean MD, Kelsey KT, Marsit CJ. MicroRNA expression in head and neck cancer associates with alcohol consumption and survival. Carcinogenesis 2009, 30(12):2059-2063. 10.1093/carcin/bgp277, 2792323, 19901002.
14. Christensen BC, Moyer BJ, Avissar M, Ouellet LG, Plaza SL, McClean MD, Marsit CJ, Kelsey KT. A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers. Carcinogenesis 2009, 30(6):1003-1007. 10.1093/carcin/bgp099, 2691138, 19380522.
15. Avissar M, Christensen BC, Kelsey KT, Marsit CJ. MicroRNA expression ratio is predictive of head and neck squamous cell carcinoma. Clin Cancer Res 2009, 15(8):2850-2855. 10.1158/1078-0432.CCR-08-3131, 2669849, 19351747.
16. Fletcher AM, Heaford AC, Trask DK. Detection of metastatic head and neck squamous cell carcinoma using the relative expression of tissue-specific mir-205. Transl Oncol 2008, 1(4):202-208. 2582169, 19043531.
17. Tanzer A, Amemiya CT, Kim CB, Stadler PF. Evolution of microRNAs located within Hox gene clusters. J Exp Zool B Mol Dev Evol 2005, 304B(1):75-85.
18. Yekta S, Tabin CJ, Bartel DP. MicroRNAs in the Hox network: an apparent link to posterior prevalence. Nat Rev Genet 2008, 9(10):789-796. 10.1038/nrg2400, 2710959, 18781158.
19. Breitling R, Armengaud P, Amtmann A, Herzyk P. Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. FEBS Lett 2004, 573(1-3):83-92.
20. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method. Methods 2001, 25(4):402-408. 10.1006/meth.2001.1262, 11846609.
21. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002, 3(7):@@. Epub 2002 Jun 18.
22. Klingbeil MFG, Herson MR, Cristo EB, Pinto DD, Yoshito D, Mathor MB. Comparison of two cellular harvesting methods for primary human oral culture of keratinocytes. Cell Tissue Bank 2009, 10(3):197-204. 10.1007/s10561-009-9122-7, 19184532.
23. Ziober AF, Patel KR, Alawi F, Gimotty P, Weber RS, Feldman MM, Chalian AA, Weinstein GS, Hunt J, Ziober BL. Identification of a gene signature for rapid screening of oral squamous cell carcinoma. Clin Cancer Res 2006, 12(20 Pt 1):5960-5971.
24. Severino P, Alvares AM, Michaluart P, Okamoto OK, Nunes FD, Moreira-Filho CA, Tajara EH. Global gene expression profiling of oral cavity cancers suggests molecular heterogeneity within anatomic subsites. BMC Res Notes 2008, 1:113. 10.1186/1756-0500-1-113, 2632665, 19014556.
25. Wu BH, Xiong XP, Jia J, Zhang WF. MicroRNAs: new actors in the oral cancer scene. Oral Oncol 2011, 47(5):314-319. 10.1016/j.oraloncology.2011.03.019, 21474366.
26. Tran N, O'Brien CJ, Clark J, Rose B. Potential role of micro-RNAs in head and neck tumorigenesis. Head Neck 2010, 32(8):1099-1111. 10.1002/hed.21356, 20213828.
27. Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, Tomida S, Yatabe Y, Kawahara K, Sekido Y, Takahashi T. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005, 65(21):9628-9632. 10.1158/0008-5472.CAN-05-2352, 16266980.
28. Olive V, Jiang I, He L. mir-17-92, a cluster of miRNAs in the midst of the cancer network. Int J Biochem Cell Biol 2010, 42(8):1348-1354. 10.1016/j.biocel.2010.03.004, 3681296, 20227518.
29. Woods K, Thomson JM, Hammond SM. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem 2007, 282(4):2130-2134.
30. Aguda BD, Kim Y, Piper-Hunter MG, Friedman A, Marsh CB. MicroRNA regulation of a cancer network: consequences of the feedback loops involving miR-17-92, E2F, and Myc. Proc Natl Acad Sci U S A 2008, 105(50):19678-19683. 10.1073/pnas.0811166106, 2598727, 19066217.
31. Xu B, Liu P, Li J, Lu H. c-MYC depletion potentiates cisplatin-induced apoptosis in head and neck squamous cell carcinoma: involvement of TSP-1 up-regulation. Ann Oncol 2010, 21(3):670-672.
32. Mestdagh P, Bostrom AK, Impens F, Fredlund E, Van Peer G, De Antonellis P, von Stedingk K, Ghesquiere B, Schulte S, Dews M, et al. The miR-17-92 microRNA cluster regulates multiple components of the TGF-beta pathway in neuroblastoma. Mol Cell 2010, 40(5):762-773. 10.1016/j.molcel.2010.11.038, 3032380, 21145484.
33. Kumar B, Yadav A, Lang J, Teknos TN, Kumar P. Dysregulation of microRNA-34a expression in head and neck squamous cell carcinoma promotes tumor growth and tumor angiogenesis. PLoS One 2012, 7(5):e37601. 10.1371/journal.pone.0037601, 3358265, 22629428.
34. Corney DC, Flesken-Nikitin A, Godwin AK, Wang W, Nikitin AY. MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res 2007, 67(18):8433-8438. 10.1158/0008-5472.CAN-07-1585, 17823410.
35. Hermeking H. The miR-34 family in cancer and apoptosis. Cell Death Differ 2010, 17(2):193-199. 10.1038/cdd.2009.56, 19461653.
36. Koch WM, Brennan JA, Zahurak M, Goodman SN, Westra WH, Schwab D, Yoo GH, Lee DJ, Forastiere AA, Sidransky D. p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma. J Natl Cancer Inst 1996, 88(21):1580-1586. 10.1093/jnci/88.21.1580, 8901856.
37. Wong TS, Liu XB, Ho ACW, Yuen APW, Ng RWM, Wei WI. Identification of pyruvate kinase type M2 as potential oncoprotein in squamous cell carcinoma of tongue through microRNA profiling. Int J Cancer 2008, 123(2):251-257. 10.1002/ijc.23583, 18464261.
38. Kinoshita T, Nohata N, Watanabe-Takano H, Yoshino H, Hidaka H, Fujimura L, Fuse M, Yamasaki T, Enokida H, Nakagawa M, et al. Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma. Int J Oncol 2012, 40(6):1770-1778.
39. Kinoshita T, Nohata N, Fuse M, Hanazawa T, Kikkawa N, Fujimura L, Watanabe-Takano H, Yamada Y, Yoshino H, Enokida H, et al. Tumor suppressive microRNA-133a regulates novel targets: Moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma. Biochem Biophys Res Commun 2012, 418(2):378-383. 10.1016/j.bbrc.2012.01.030, 22266319.
40. Lund AH. miR-10 in development and cancer. Cell Death Differ 2010, 17(2):209-214. 10.1038/cdd.2009.58, 19461655.
41. Chen C, Zhang Y, Zhang L, Weakley SM, Yao Q. MicroRNA-196: critical roles and clinical applications in development and cancer. J Cell Mol Med 2011, 15(1):14-23. 10.1111/j.1582-4934.2010.01219.x, 3276076, 21091634.
42. Yekta S, Shih IH, Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science 2004, 304(5670):594-596. 10.1126/science.1097434, 15105502.
43. Schimanski CC, Frerichs K, Rahman F, Berger M, Lang H, Galle PR, Moehler M, Gockel I. High miR-196a levels promote the oncogenic phenotype of colorectal cancer cells. World J Gastroenterol 2009, 15(17):2089-2096. 10.3748/wjg.15.2089, 2678579, 19418581.
44. Baffa R, Fassan M, Volinia S, O'Hara B, Liu CG, Palazzo JP, Gardiman M, Rugge M, Gomella LG, Croce CM, et al. MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets. J Pathol 2009, 219(2):214-221. 10.1002/path.2586, 19593777.
45. Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA 10b in breast cancer. Nature 2007, 449(7163):682-U682. 10.1038/nature06174, 17898713.
46. Wynter CVA. The dialectics of cancer: a theory of the initiation and development of cancer through errors in RNAi. Med Hypotheses 2006, 66(3):612-635. 10.1016/j.mehy.2005.10.024, 16359827.
47. Oganesian L, Karlseder J. Mammalian 5' C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance. Mol Cell 2011, 42(2):224-236. 10.1016/j.molcel.2011.03.015, 3082866, 21504833.
48. Garzon R, Pichiorri F, Palumbo T, Iuliano R, Cimmino A, Aqeilan R, Volinia S, Bhatt D, Alder H, Marcucci G, et al. MicroRNA fingerprints during human megakaryocytopoiesis. Proc Natl Acad Sci U S A 2006, 103(13):5078-5083. 10.1073/pnas.0600587103, 1458797, 16549775.
49. Tian YY, Luo AP, Cai YR, Su Q, Ding F, Chen HY, Liu ZH. MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines. J Biol Chem 2010, 285(11):7986-7994. 10.1074/jbc.M109.062877, 2832949, 20075075.
50. Luthra R, Singh RR, Luthra MG, Li YX, Hannah C, Romans AM, Barkoh BA, Chen SS, Ensor J, Maru DM, et al. MicroRNA-196a targets annexin A1: a microRNA-mediated mechanism of annexin A1 downregulation in cancers. Oncogene 2008, 27(52):6667-6678. 10.1038/onc.2008.256, 18663355.
51. Maru DM, Singh RR, Hannah C, Albarracin CT, Li YX, Abraham R, Romans AM, Yao H, Luthra MG, Anandasabapathy S, et al. MicroRNA-196a is a potential marker of progression during Barrett's metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagus. Am J Pathol 2009, 174(5):1940-1948. 10.2353/ajpath.2009.080718, 2671281, 19342367.
52. Pedrero JMG, Fernandez MP, Morgan RO, Zapatero AH, Gonzalez MV, Nieto CS, Rodrigo JP. Annexin A1 down-regulation in head and neck cancer is associated with epithelial differentiation status. Am J Pathol 2004, 164(1):73-79. 10.1016/S0002-9440(10)63098-2, 1602219, 14695321.
53. Alves VA, Nonogaki S, Cury PM, Wunsch-Filho V, de Carvalho MB, Michaluart-Junior P, Moyses RA, Curioni OA, Figueiredo DL, Scapulatempo-Neto C, et al. Annexin A1 subcellular expression in laryngeal squamous cell carcinoma. Histopathology 2008, 53(6):715-727. 10.1111/j.1365-2559.2008.03186.x, 19076685.
54. Melino G, De Laurenzi V, Vousden KH. p73: Friend or foe in tumorigenesis. Nat Rev Cancer 2002, 2(8):605-615. 10.1038/nrc861, 12154353.
55. New DC, Wong YH. Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression. J Mol Signal 2007, 2:2. 10.1186/1750-2187-2-2, 1808056, 17319972.
56. Cassell A, Grandis JR. Investigational EGFR-targeted therapy in head and neck squamous cell carcinoma. Expert Opin Investig Drugs 2010, 19(6):709-722. 10.1517/13543781003769844, 2947445, 20415598.
57. Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011, 333(6046):1154-1157. 10.1126/science.1206923, 3162986, 21798897.