메뉴 건너뛰기




Volumn 19, Issue 21, 2013, Pages 5927-5939

A negative feedback of the HIF-1α pathway via interferon-stimulated gene 15 and ISGylation

Author keywords

[No Author keywords available]

Indexed keywords

DEFEROXAMINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; INTERFERON; INTERFERON STIMULATED GENE 15 PROTEIN; MESSENGER RNA; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 84887093706     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-0018     Document Type: Article
Times cited : (32)

References (50)
  • 1
    • 33749346301 scopus 로고    scopus 로고
    • Modification of proteins by ubiquitin and ubiquitin-like proteins
    • Kerscher O, Felberbaum R, Hochstrasser M. Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu Rev Cell Dev Biol 2006;22: 159-80.
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 159-180
    • Kerscher, O.1    Felberbaum, R.2    Hochstrasser, M.3
  • 2
    • 0032493368 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1alpha is mediated by anO2-dependent degradation domain via the ubiquitin-proteasome pathway
    • Huang LE, Gu J, Schau M, Bunn HF. Regulation of hypoxia-inducible factor 1alpha is mediated by anO2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A 1998;95: 7987-92.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7987-7992
    • Huang, L.E.1    Gu, J.2    Schau, M.3    Bunn, H.F.4
  • 3
    • 0034663894 scopus 로고    scopus 로고
    • Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein
    • Tanimoto K, Makino Y, Pereira T, Poellinger L. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein. EMBO J 2000;19: 4298-309.
    • (2000) EMBO J , vol.19 , pp. 4298-4309
    • Tanimoto, K.1    Makino, Y.2    Pereira, T.3    Poellinger, L.4
  • 6
    • 84863545539 scopus 로고    scopus 로고
    • Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15
    • Jeon YJ, Jo MG, Yoo HM, Hong SH, Park JM, Ka SH, et al. Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15. J Clin Invest 2012;122: 2622-36.
    • (2012) J Clin Invest , vol.122 , pp. 2622-2636
    • Jeon, Y.J.1    Jo, M.G.2    Yoo, H.M.3    Hong, S.H.4    Park, J.M.5    Ka, S.H.6
  • 9
    • 80051583598 scopus 로고    scopus 로고
    • A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression
    • Yuan WC, Lee YR, Huang SF, Lin YM, Chen TY, Chung HC, et al. A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression. Cancer Cell 2011;20: 214-28.
    • (2011) Cancer Cell , vol.20 , pp. 214-228
    • Yuan, W.C.1    Lee, Y.R.2    Huang, S.F.3    Lin, Y.M.4    Chen, T.Y.5    Chung, H.C.6
  • 11
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144: 646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 13
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
    • Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 2009;30: 1073-81.
    • (2009) Carcinogenesis , vol.30 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 14
    • 84867514301 scopus 로고    scopus 로고
    • Targeting hypoxia, HIF- 1, and tumor glucose metabolism to improve radiotherapy efficacy
    • Meijer TW, Kaanders JH, Span PN, Bussink J. Targeting hypoxia, HIF- 1, and tumor glucose metabolism to improve radiotherapy efficacy. Clin Cancer Res 2012;18: 5585-94.
    • (2012) Clin Cancer Res , vol.18 , pp. 5585-5594
    • Meijer, T.W.1    Kaanders, J.H.2    Span, P.N.3    Bussink, J.4
  • 15
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
    • Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, et al. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001;292: 468-72.
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1    Mole, D.R.2    Tian, Y.M.3    Wilson, M.I.4    Gielbert, J.5    Gaskell, S.J.6
  • 16
    • 0037097861 scopus 로고    scopus 로고
    • FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
    • Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev 2002;16: 1466-71.
    • (2002) Genes Dev , vol.16 , pp. 1466-1471
    • Lando, D.1    Peet, D.J.2    Gorman, J.J.3    Whelan, D.A.4    Whitelaw, M.L.5    Bruick, R.K.6
  • 17
    • 84866424379 scopus 로고    scopus 로고
    • Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1alpha interaction with cofactors p300/CBP
    • Yin S, Kaluz S, Devi NS, Jabbar AA, de Noronha RG, Mun J, et al. Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1alpha interaction with cofactors p300/CBP. Clin Cancer Res 2012;18: 6623-33.
    • (2012) Clin Cancer Res , vol.18 , pp. 6623-6633
    • Yin, S.1    Kaluz, S.2    Devi, N.S.3    Jabbar, A.A.4    De Noronha, R.G.5    Mun, J.6
  • 18
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A 1995;92: 5510-4.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 19
    • 0036000028 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia
    • Lang KJ, Kappel A, Goodall GJ. Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia. Mol Biol Cell 2002;13: 1792-801.
    • (2002) Mol Biol Cell , vol.13 , pp. 1792-1801
    • Lang, K.J.1    Kappel, A.2    Goodall, G.J.3
  • 20
    • 84867531311 scopus 로고    scopus 로고
    • Sorafenib inhibits hypoxia-inducible factor-1alpha synthesis: Implications for antiangiogenic activity in hepatocellular carcinoma
    • Liu LP, Ho RL, Chen GG, Lai PB. Sorafenib inhibits hypoxia-inducible factor-1alpha synthesis: implications for antiangiogenic activity in hepatocellular carcinoma. Clin Cancer Res 2012;18: 5662-71.
    • (2012) Clin Cancer Res , vol.18 , pp. 5662-5671
    • Liu, L.P.1    Ho, R.L.2    Chen, G.G.3    Lai, P.B.4
  • 21
    • 84866985744 scopus 로고    scopus 로고
    • Conceptus-derived prostaglandins regulate endometrial function in sheep
    • Dorniak P, Bazer FW, Wu G, Spencer TE. Conceptus-derived prostaglandins regulate endometrial function in sheep. Biol Reprod 2012; 87: 9, 1-7.
    • (2012) Biol Reprod , vol.87 , Issue.9 , pp. 1-7
    • Dorniak, P.1    Bazer, F.W.2    Wu, G.3    Spencer, T.E.4
  • 22
    • 41549128043 scopus 로고    scopus 로고
    • Progesterone and interferon tau regulate hypoxia-inducible factors in the endometrium of the ovine uterus
    • Song G, Kim J, Bazer FW, Spencer TE. Progesterone and interferon tau regulate hypoxia-inducible factors in the endometrium of the ovine uterus. Endocrinology 2008;149: 1926-34.
    • (2008) Endocrinology , vol.149 , pp. 1926-1934
    • Song, G.1    Kim, J.2    Bazer, F.W.3    Spencer, T.E.4
  • 23
    • 51749089798 scopus 로고    scopus 로고
    • Interdependent roles for hypoxia inducible factor and nuclear factor-kappaB in hypoxic inflammation
    • Taylor CT. Interdependent roles for hypoxia inducible factor and nuclear factor-kappaB in hypoxic inflammation. J Physiol 2008;586: 4055-9.
    • (2008) J Physiol , vol.586 , pp. 4055-4059
    • Taylor, C.T.1
  • 24
    • 0023160888 scopus 로고
    • Interferon induces a 15- kilodalton protein exhibiting marked homology to ubiquitin
    • Haas AL, Ahrens P, Bright PM, Ankel H. Interferon induces a 15- kilodalton protein exhibiting marked homology to ubiquitin. J Biol Chem 1987;262: 11315-23.
    • (1987) J Biol Chem , vol.262 , pp. 11315-11323
    • Haas, A.L.1    Ahrens, P.2    Bright, P.M.3    Ankel, H.4
  • 25
    • 57449088412 scopus 로고    scopus 로고
    • An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
    • Weichselbaum RR, Ishwaran H, Yoon T, Nuyten DS, Baker SW, Khodarev N, et al. An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc Natl Acad Sci U S A 2008;105: 18490-5.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 18490-18495
    • Weichselbaum, R.R.1    Ishwaran, H.2    Yoon, T.3    Nuyten, D.S.4    Baker, S.W.5    Khodarev, N.6
  • 27
    • 33751257187 scopus 로고    scopus 로고
    • The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: Friend or foe?
    • Andersen JB, Hassel BA. The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: friend or foe? Cytokine Growth Factor Rev 2006;17: 411-21.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 411-421
    • Andersen, J.B.1    Hassel, B.A.2
  • 28
    • 67651122930 scopus 로고    scopus 로고
    • Expression, regulation and function of the ISGylation system in prostate cancer
    • Kiessling A, Hogrefe C, Erb S, Bobach C, Fuessel S, Wessjohann L, et al. Expression, regulation and function of the ISGylation system in prostate cancer. Oncogene 2009;28: 2606-20.
    • (2009) Oncogene , vol.28 , pp. 2606-2620
    • Kiessling, A.1    Hogrefe, C.2    Erb, S.3    Bobach, C.4    Fuessel, S.5    Wessjohann, L.6
  • 29
    • 84856554267 scopus 로고    scopus 로고
    • Oncolytic Sindbis virus targets tumors defective in the interferon response and induces significant bystander antitumor immunity in vivo
    • Huang PY, Guo JH, Hwang LH. Oncolytic Sindbis virus targets tumors defective in the interferon response and induces significant bystander antitumor immunity in vivo. Mol Ther 2012;20: 298-305.
    • (2012) Mol Ther , vol.20 , pp. 298-305
    • Huang, P.Y.1    Guo, J.H.2    Hwang, L.H.3
  • 31
    • 2142695181 scopus 로고    scopus 로고
    • Interleukin-2- and interferon alfa-2a-based immunochemotherapy in advanced renal cell carcinoma: A Prospectively Randomized Trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN)
    • Atzpodien J, Kirchner H, Jonas U, Bergmann L, Schott H, Heynemann H, et al. Interleukin-2- and interferon alfa-2a-based immunochemotherapy in advanced renal cell carcinoma: a Prospectively Randomized Trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN). J Clin Oncol 2004;22: 1188-94.
    • (2004) J Clin Oncol , vol.22 , pp. 1188-1194
    • Atzpodien, J.1    Kirchner, H.2    Jonas, U.3    Bergmann, L.4    Schott, H.5    Heynemann, H.6
  • 32
    • 0023876086 scopus 로고
    • A 15-kDa interferon-induced protein is derived by COOH-terminal processing of a 17-kDa precursor
    • Knight E Jr., Fahey D, Cordova B, Hillman M, Kutny R, Reich N, et al. A 15-kDa interferon-induced protein is derived by COOH-terminal processing of a 17-kDa precursor. J Biol Chem 1988;263: 4520-2.
    • (1988) J Biol Chem , vol.263 , pp. 4520-4522
    • Knight Jr., E.1    Fahey, D.2    Cordova, B.3    Hillman, M.4    Kutny, R.5    Reich, N.6
  • 33
    • 33746089547 scopus 로고    scopus 로고
    • HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type i IFN-induced ISGylation of protein targets
    • Wong JJ, Pung YF, Sze NS, Chin KC. HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets. Proc Natl Acad Sci U S A 2006;103: 10735-40.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 10735-10740
    • Wong, J.J.1    Pung, Y.F.2    Sze, N.S.3    Chin, K.C.4
  • 34
    • 2442717751 scopus 로고    scopus 로고
    • The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein
    • Zhao C, Beaudenon SL, Kelley ML, Waddell MB, Yuan W, Schulman BA, et al. The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein. Proc Natl Acad Sci U S A 2004;101: 7578-82.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 7578-7582
    • Zhao, C.1    Beaudenon, S.L.2    Kelley, M.L.3    Waddell, M.B.4    Yuan, W.5    Schulman, B.A.6
  • 35
    • 31544460359 scopus 로고    scopus 로고
    • Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway
    • Desai SD, Haas AL, Wood LM, Tsai YC, Pestka S, Rubin EH, et al. Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway. Cancer Res 2006;66: 921-8.
    • (2006) Cancer Res , vol.66 , pp. 921-928
    • Desai, S.D.1    Haas, A.L.2    Wood, L.M.3    Tsai, Y.C.4    Pestka, S.5    Rubin, E.H.6
  • 36
    • 66349136840 scopus 로고    scopus 로고
    • TTK/hMps1 mediates the p53- dependent postmitotic checkpoint by phosphorylating p53 at Thr18
    • Huang YF, Chang MD, Shieh SY. TTK/hMps1 mediates the p53- dependent postmitotic checkpoint by phosphorylating p53 at Thr18. Mol Cell Biol 2009;29: 2935-44.
    • (2009) Mol Cell Biol , vol.29 , pp. 2935-2944
    • Huang, Y.F.1    Chang, M.D.2    Shieh, S.Y.3
  • 37
    • 62249140224 scopus 로고    scopus 로고
    • The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1
    • Yeh YH, Huang YF, Lin TY, Shieh SY. The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1. Oncogene 2009;28: 1366-78.
    • (2009) Oncogene , vol.28 , pp. 1366-1378
    • Yeh, Y.H.1    Huang, Y.F.2    Lin, T.Y.3    Shieh, S.Y.4
  • 38
    • 33847001685 scopus 로고    scopus 로고
    • ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP
    • Okumura F, Zou W, Zhang DE. ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP. Genes Dev 2007;21: 255-60.
    • (2007) Genes Dev , vol.21 , pp. 255-260
    • Okumura, F.1    Zou, W.2    Zhang, D.E.3
  • 40
    • 65949103633 scopus 로고    scopus 로고
    • HAF: The new player in oxygen-independent HIF- 1alpha degradation
    • Koh MY, Powis G. HAF: the new player in oxygen-independent HIF- 1alpha degradation. Cell Cycle 2009;8: 1359-66.
    • (2009) Cell Cycle , vol.8 , pp. 1359-1366
    • Koh, M.Y.1    Powis, G.2
  • 41
    • 35548935098 scopus 로고    scopus 로고
    • SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia
    • Cheng J, Kang X, Zhang S, Yeh ET. SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell 2007;131: 584-95.
    • (2007) Cell , vol.131 , pp. 584-595
    • Cheng, J.1    Kang, X.2    Zhang, S.3    Yeh, E.T.4
  • 42
    • 0141643358 scopus 로고    scopus 로고
    • Hypoxia up-regulates prolyl hydroxylase activity: A feedback mechanism that limits HIF-1 responses during reoxygenation
    • D'Angelo G, Duplan E, Boyer N, Vigne P, Frelin C. Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation. J Biol Chem 2003;278: 38183-7.
    • (2003) J Biol Chem , vol.278 , pp. 38183-38187
    • D'Angelo, G.1    Duplan, E.2    Boyer, N.3    Vigne, P.4    Frelin, C.5
  • 43
    • 33747660292 scopus 로고    scopus 로고
    • Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygensensing system
    • Stiehl DP, Wirthner R, Koditz J, Spielmann P, Camenisch G, Wenger RH. Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygensensing system. J Biol Chem 2006;281: 23482-91.
    • (2006) J Biol Chem , vol.281 , pp. 23482-23491
    • Stiehl, D.P.1    Wirthner, R.2    Koditz, J.3    Spielmann, P.4    Camenisch, G.5    Wenger, R.H.6
  • 44
    • 37349025432 scopus 로고    scopus 로고
    • FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2
    • Bakker WJ, Harris IS, Mak TW. FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2. Mol Cell 2007;28: 941-53.
    • (2007) Mol Cell , vol.28 , pp. 941-953
    • Bakker, W.J.1    Harris, I.S.2    Mak, T.W.3
  • 46
    • 77956805884 scopus 로고    scopus 로고
    • Feedback regulators of hypoxia-inducible factors and their role in cancer biology
    • Henze AT, Acker T. Feedback regulators of hypoxia-inducible factors and their role in cancer biology. Cell Cycle 2010;9: 2749-63.
    • (2010) Cell Cycle , vol.9 , pp. 2749-2763
    • Henze, A.T.1    Acker, T.2
  • 47
    • 39849098721 scopus 로고    scopus 로고
    • SAG/ROC2/RBX2 is a HIF-1 target gene that promotes HIF-1 alpha ubiquitination and degradation
    • Tan M, Gu Q, He H, Pamarthy D, Semenza GL, Sun Y. SAG/ROC2/RBX2 is a HIF-1 target gene that promotes HIF-1 alpha ubiquitination and degradation. Oncogene 2008;27: 1404-11.
    • (2008) Oncogene , vol.27 , pp. 1404-1411
    • Tan, M.1    Gu, Q.2    He, H.3    Pamarthy, D.4    Semenza, G.L.5    Sun, Y.6
  • 48
    • 4344645563 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases
    • Marxsen JH, Stengel P, Doege K, Heikkinen P, Jokilehto T, Wagner T, et al. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases. Biochem J 2004;381: 761-7.
    • (2004) Biochem J , vol.381 , pp. 761-767
    • Marxsen, J.H.1    Stengel, P.2    Doege, K.3    Heikkinen, P.4    Jokilehto, T.5    Wagner, T.6
  • 49
    • 38349189787 scopus 로고    scopus 로고
    • Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugation
    • Kim MJ, Hwang SY, Imaizumi T, Yoo JY. Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugation. J Virol 2008;82: 1474-83.
    • (2008) J Virol , vol.82 , pp. 1474-1483
    • Kim, M.J.1    Hwang, S.Y.2    Imaizumi, T.3    Yoo, J.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.