-
2
-
-
0032493368
-
Regulation of hypoxia-inducible factor 1alpha is mediated by anO2-dependent degradation domain via the ubiquitin-proteasome pathway
-
Huang LE, Gu J, Schau M, Bunn HF. Regulation of hypoxia-inducible factor 1alpha is mediated by anO2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A 1998;95: 7987-92.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7987-7992
-
-
Huang, L.E.1
Gu, J.2
Schau, M.3
Bunn, H.F.4
-
3
-
-
0034663894
-
Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein
-
Tanimoto K, Makino Y, Pereira T, Poellinger L. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein. EMBO J 2000;19: 4298-309.
-
(2000)
EMBO J
, vol.19
, pp. 4298-4309
-
-
Tanimoto, K.1
Makino, Y.2
Pereira, T.3
Poellinger, L.4
-
5
-
-
84857702419
-
Molecular pathways: Hypoxia response in immune cells fighting or promoting cancer
-
Palazon A, Aragones J, Morales-Kastresana A, de Landazuri MO, Melero I. Molecular pathways: hypoxia response in immune cells fighting or promoting cancer. Clin Cancer Res 2012;18: 1207-13.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1207-1213
-
-
Palazon, A.1
Aragones, J.2
Morales-Kastresana, A.3
De Landazuri, M.O.4
Melero, I.5
-
6
-
-
84863545539
-
Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15
-
Jeon YJ, Jo MG, Yoo HM, Hong SH, Park JM, Ka SH, et al. Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15. J Clin Invest 2012;122: 2622-36.
-
(2012)
J Clin Invest
, vol.122
, pp. 2622-2636
-
-
Jeon, Y.J.1
Jo, M.G.2
Yoo, H.M.3
Hong, S.H.4
Park, J.M.5
Ka, S.H.6
-
7
-
-
49849102784
-
ISG15 as a novel tumor biomarker for drug sensitivity
-
Desai SD, Wood LM, Tsai YC, Hsieh TS, Marks JR, Scott GL, et al. ISG15 as a novel tumor biomarker for drug sensitivity. Mol Cancer Ther 2008;7: 1430-9.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1430-1439
-
-
Desai, S.D.1
Wood, L.M.2
Tsai, Y.C.3
Hsieh, T.S.4
Marks, J.R.5
Scott, G.L.6
-
8
-
-
0037443090
-
Protein ISGylation modulates the JAK-STAT signaling pathway
-
Malakhova OA, Yan M, Malakhov MP, Yuan Y, Ritchie KJ, Kim KI, et al. Protein ISGylation modulates the JAK-STAT signaling pathway. Genes Dev 2003;17: 455-60.
-
(2003)
Genes Dev
, vol.17
, pp. 455-460
-
-
Malakhova, O.A.1
Yan, M.2
Malakhov, M.P.3
Yuan, Y.4
Ritchie, K.J.5
Kim, K.I.6
-
9
-
-
80051583598
-
A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression
-
Yuan WC, Lee YR, Huang SF, Lin YM, Chen TY, Chung HC, et al. A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression. Cancer Cell 2011;20: 214-28.
-
(2011)
Cancer Cell
, vol.20
, pp. 214-228
-
-
Yuan, W.C.1
Lee, Y.R.2
Huang, S.F.3
Lin, Y.M.4
Chen, T.Y.5
Chung, H.C.6
-
11
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144: 646-74.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
13
-
-
67650151005
-
Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
-
Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 2009;30: 1073-81.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1073-1081
-
-
Colotta, F.1
Allavena, P.2
Sica, A.3
Garlanda, C.4
Mantovani, A.5
-
14
-
-
84867514301
-
Targeting hypoxia, HIF- 1, and tumor glucose metabolism to improve radiotherapy efficacy
-
Meijer TW, Kaanders JH, Span PN, Bussink J. Targeting hypoxia, HIF- 1, and tumor glucose metabolism to improve radiotherapy efficacy. Clin Cancer Res 2012;18: 5585-94.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5585-5594
-
-
Meijer, T.W.1
Kaanders, J.H.2
Span, P.N.3
Bussink, J.4
-
15
-
-
0035917808
-
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, et al. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001;292: 468-72.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
-
16
-
-
0037097861
-
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
-
Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev 2002;16: 1466-71.
-
(2002)
Genes Dev
, vol.16
, pp. 1466-1471
-
-
Lando, D.1
Peet, D.J.2
Gorman, J.J.3
Whelan, D.A.4
Whitelaw, M.L.5
Bruick, R.K.6
-
17
-
-
84866424379
-
Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1alpha interaction with cofactors p300/CBP
-
Yin S, Kaluz S, Devi NS, Jabbar AA, de Noronha RG, Mun J, et al. Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1alpha interaction with cofactors p300/CBP. Clin Cancer Res 2012;18: 6623-33.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 6623-6633
-
-
Yin, S.1
Kaluz, S.2
Devi, N.S.3
Jabbar, A.A.4
De Noronha, R.G.5
Mun, J.6
-
18
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A 1995;92: 5510-4.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
19
-
-
0036000028
-
Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia
-
Lang KJ, Kappel A, Goodall GJ. Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia. Mol Biol Cell 2002;13: 1792-801.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 1792-1801
-
-
Lang, K.J.1
Kappel, A.2
Goodall, G.J.3
-
20
-
-
84867531311
-
Sorafenib inhibits hypoxia-inducible factor-1alpha synthesis: Implications for antiangiogenic activity in hepatocellular carcinoma
-
Liu LP, Ho RL, Chen GG, Lai PB. Sorafenib inhibits hypoxia-inducible factor-1alpha synthesis: implications for antiangiogenic activity in hepatocellular carcinoma. Clin Cancer Res 2012;18: 5662-71.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5662-5671
-
-
Liu, L.P.1
Ho, R.L.2
Chen, G.G.3
Lai, P.B.4
-
21
-
-
84866985744
-
Conceptus-derived prostaglandins regulate endometrial function in sheep
-
Dorniak P, Bazer FW, Wu G, Spencer TE. Conceptus-derived prostaglandins regulate endometrial function in sheep. Biol Reprod 2012; 87: 9, 1-7.
-
(2012)
Biol Reprod
, vol.87
, Issue.9
, pp. 1-7
-
-
Dorniak, P.1
Bazer, F.W.2
Wu, G.3
Spencer, T.E.4
-
22
-
-
41549128043
-
Progesterone and interferon tau regulate hypoxia-inducible factors in the endometrium of the ovine uterus
-
Song G, Kim J, Bazer FW, Spencer TE. Progesterone and interferon tau regulate hypoxia-inducible factors in the endometrium of the ovine uterus. Endocrinology 2008;149: 1926-34.
-
(2008)
Endocrinology
, vol.149
, pp. 1926-1934
-
-
Song, G.1
Kim, J.2
Bazer, F.W.3
Spencer, T.E.4
-
23
-
-
51749089798
-
Interdependent roles for hypoxia inducible factor and nuclear factor-kappaB in hypoxic inflammation
-
Taylor CT. Interdependent roles for hypoxia inducible factor and nuclear factor-kappaB in hypoxic inflammation. J Physiol 2008;586: 4055-9.
-
(2008)
J Physiol
, vol.586
, pp. 4055-4059
-
-
Taylor, C.T.1
-
24
-
-
0023160888
-
Interferon induces a 15- kilodalton protein exhibiting marked homology to ubiquitin
-
Haas AL, Ahrens P, Bright PM, Ankel H. Interferon induces a 15- kilodalton protein exhibiting marked homology to ubiquitin. J Biol Chem 1987;262: 11315-23.
-
(1987)
J Biol Chem
, vol.262
, pp. 11315-11323
-
-
Haas, A.L.1
Ahrens, P.2
Bright, P.M.3
Ankel, H.4
-
25
-
-
57449088412
-
An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
-
Weichselbaum RR, Ishwaran H, Yoon T, Nuyten DS, Baker SW, Khodarev N, et al. An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc Natl Acad Sci U S A 2008;105: 18490-5.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 18490-18495
-
-
Weichselbaum, R.R.1
Ishwaran, H.2
Yoon, T.3
Nuyten, D.S.4
Baker, S.W.5
Khodarev, N.6
-
26
-
-
33646848595
-
Stage-associated overexpression of the ubiquitin-like protein, ISG15, in bladder cancer
-
Andersen JB, Aaboe M, Borden EC, Goloubeva OG, Hassel BA, Orntoft TF. Stage-associated overexpression of the ubiquitin-like protein, ISG15, in bladder cancer. Br J Cancer 2006;94: 1465-71.
-
(2006)
Br J Cancer
, vol.94
, pp. 1465-1471
-
-
Andersen, J.B.1
Aaboe, M.2
Borden, E.C.3
Goloubeva, O.G.4
Hassel, B.A.5
Orntoft, T.F.6
-
27
-
-
33751257187
-
The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: Friend or foe?
-
Andersen JB, Hassel BA. The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: friend or foe? Cytokine Growth Factor Rev 2006;17: 411-21.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 411-421
-
-
Andersen, J.B.1
Hassel, B.A.2
-
28
-
-
67651122930
-
Expression, regulation and function of the ISGylation system in prostate cancer
-
Kiessling A, Hogrefe C, Erb S, Bobach C, Fuessel S, Wessjohann L, et al. Expression, regulation and function of the ISGylation system in prostate cancer. Oncogene 2009;28: 2606-20.
-
(2009)
Oncogene
, vol.28
, pp. 2606-2620
-
-
Kiessling, A.1
Hogrefe, C.2
Erb, S.3
Bobach, C.4
Fuessel, S.5
Wessjohann, L.6
-
29
-
-
84856554267
-
Oncolytic Sindbis virus targets tumors defective in the interferon response and induces significant bystander antitumor immunity in vivo
-
Huang PY, Guo JH, Hwang LH. Oncolytic Sindbis virus targets tumors defective in the interferon response and induces significant bystander antitumor immunity in vivo. Mol Ther 2012;20: 298-305.
-
(2012)
Mol Ther
, vol.20
, pp. 298-305
-
-
Huang, P.Y.1
Guo, J.H.2
Hwang, L.H.3
-
30
-
-
67049158197
-
Impaired interferon signaling is a common immune defect in human cancer
-
Critchley-Thorne RJ, Simons DL, Yan N, Miyahira AK, Dirbas FM, Johnson DL, et al. Impaired interferon signaling is a common immune defect in human cancer. Proc Natl Acad Sci U S A 2009;106: 9010-5.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9010-9015
-
-
Critchley-Thorne, R.J.1
Simons, D.L.2
Yan, N.3
Miyahira, A.K.4
Dirbas, F.M.5
Johnson, D.L.6
-
31
-
-
2142695181
-
Interleukin-2- and interferon alfa-2a-based immunochemotherapy in advanced renal cell carcinoma: A Prospectively Randomized Trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN)
-
Atzpodien J, Kirchner H, Jonas U, Bergmann L, Schott H, Heynemann H, et al. Interleukin-2- and interferon alfa-2a-based immunochemotherapy in advanced renal cell carcinoma: a Prospectively Randomized Trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN). J Clin Oncol 2004;22: 1188-94.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1188-1194
-
-
Atzpodien, J.1
Kirchner, H.2
Jonas, U.3
Bergmann, L.4
Schott, H.5
Heynemann, H.6
-
32
-
-
0023876086
-
A 15-kDa interferon-induced protein is derived by COOH-terminal processing of a 17-kDa precursor
-
Knight E Jr., Fahey D, Cordova B, Hillman M, Kutny R, Reich N, et al. A 15-kDa interferon-induced protein is derived by COOH-terminal processing of a 17-kDa precursor. J Biol Chem 1988;263: 4520-2.
-
(1988)
J Biol Chem
, vol.263
, pp. 4520-4522
-
-
Knight Jr., E.1
Fahey, D.2
Cordova, B.3
Hillman, M.4
Kutny, R.5
Reich, N.6
-
33
-
-
33746089547
-
HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type i IFN-induced ISGylation of protein targets
-
Wong JJ, Pung YF, Sze NS, Chin KC. HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets. Proc Natl Acad Sci U S A 2006;103: 10735-40.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10735-10740
-
-
Wong, J.J.1
Pung, Y.F.2
Sze, N.S.3
Chin, K.C.4
-
34
-
-
2442717751
-
The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein
-
Zhao C, Beaudenon SL, Kelley ML, Waddell MB, Yuan W, Schulman BA, et al. The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein. Proc Natl Acad Sci U S A 2004;101: 7578-82.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7578-7582
-
-
Zhao, C.1
Beaudenon, S.L.2
Kelley, M.L.3
Waddell, M.B.4
Yuan, W.5
Schulman, B.A.6
-
35
-
-
31544460359
-
Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway
-
Desai SD, Haas AL, Wood LM, Tsai YC, Pestka S, Rubin EH, et al. Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway. Cancer Res 2006;66: 921-8.
-
(2006)
Cancer Res
, vol.66
, pp. 921-928
-
-
Desai, S.D.1
Haas, A.L.2
Wood, L.M.3
Tsai, Y.C.4
Pestka, S.5
Rubin, E.H.6
-
36
-
-
66349136840
-
TTK/hMps1 mediates the p53- dependent postmitotic checkpoint by phosphorylating p53 at Thr18
-
Huang YF, Chang MD, Shieh SY. TTK/hMps1 mediates the p53- dependent postmitotic checkpoint by phosphorylating p53 at Thr18. Mol Cell Biol 2009;29: 2935-44.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2935-2944
-
-
Huang, Y.F.1
Chang, M.D.2
Shieh, S.Y.3
-
37
-
-
62249140224
-
The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1
-
Yeh YH, Huang YF, Lin TY, Shieh SY. The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1. Oncogene 2009;28: 1366-78.
-
(2009)
Oncogene
, vol.28
, pp. 1366-1378
-
-
Yeh, Y.H.1
Huang, Y.F.2
Lin, T.Y.3
Shieh, S.Y.4
-
38
-
-
33847001685
-
ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP
-
Okumura F, Zou W, Zhang DE. ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP. Genes Dev 2007;21: 255-60.
-
(2007)
Genes Dev
, vol.21
, pp. 255-260
-
-
Okumura, F.1
Zou, W.2
Zhang, D.E.3
-
39
-
-
40249113328
-
Direct regulation of TWIST by HIF-1alpha promotes metastasis
-
Yang MH, Wu MZ, Chiou SH, Chen PM, Chang SY, Liu CJ, et al. Direct regulation of TWIST by HIF-1alpha promotes metastasis. Nat Cell Biol 2008;10: 295-305.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 295-305
-
-
Yang, M.H.1
Wu, M.Z.2
Chiou, S.H.3
Chen, P.M.4
Chang, S.Y.5
Liu, C.J.6
-
40
-
-
65949103633
-
HAF: The new player in oxygen-independent HIF- 1alpha degradation
-
Koh MY, Powis G. HAF: the new player in oxygen-independent HIF- 1alpha degradation. Cell Cycle 2009;8: 1359-66.
-
(2009)
Cell Cycle
, vol.8
, pp. 1359-1366
-
-
Koh, M.Y.1
Powis, G.2
-
41
-
-
35548935098
-
SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia
-
Cheng J, Kang X, Zhang S, Yeh ET. SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell 2007;131: 584-95.
-
(2007)
Cell
, vol.131
, pp. 584-595
-
-
Cheng, J.1
Kang, X.2
Zhang, S.3
Yeh, E.T.4
-
42
-
-
0141643358
-
Hypoxia up-regulates prolyl hydroxylase activity: A feedback mechanism that limits HIF-1 responses during reoxygenation
-
D'Angelo G, Duplan E, Boyer N, Vigne P, Frelin C. Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation. J Biol Chem 2003;278: 38183-7.
-
(2003)
J Biol Chem
, vol.278
, pp. 38183-38187
-
-
D'Angelo, G.1
Duplan, E.2
Boyer, N.3
Vigne, P.4
Frelin, C.5
-
43
-
-
33747660292
-
Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygensensing system
-
Stiehl DP, Wirthner R, Koditz J, Spielmann P, Camenisch G, Wenger RH. Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygensensing system. J Biol Chem 2006;281: 23482-91.
-
(2006)
J Biol Chem
, vol.281
, pp. 23482-23491
-
-
Stiehl, D.P.1
Wirthner, R.2
Koditz, J.3
Spielmann, P.4
Camenisch, G.5
Wenger, R.H.6
-
44
-
-
37349025432
-
FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2
-
Bakker WJ, Harris IS, Mak TW. FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2. Mol Cell 2007;28: 941-53.
-
(2007)
Mol Cell
, vol.28
, pp. 941-953
-
-
Bakker, W.J.1
Harris, I.S.2
Mak, T.W.3
-
45
-
-
0032900610
-
Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1
-
Bhattacharya S, Michels CL, Leung MK, Arany ZP, Kung AL, Livingston DM. Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Genes Dev 1999;13: 64-75.
-
(1999)
Genes Dev
, vol.13
, pp. 64-75
-
-
Bhattacharya, S.1
Michels, C.L.2
Leung, M.K.3
Arany, Z.P.4
Kung, A.L.5
Livingston, D.M.6
-
46
-
-
77956805884
-
Feedback regulators of hypoxia-inducible factors and their role in cancer biology
-
Henze AT, Acker T. Feedback regulators of hypoxia-inducible factors and their role in cancer biology. Cell Cycle 2010;9: 2749-63.
-
(2010)
Cell Cycle
, vol.9
, pp. 2749-2763
-
-
Henze, A.T.1
Acker, T.2
-
47
-
-
39849098721
-
SAG/ROC2/RBX2 is a HIF-1 target gene that promotes HIF-1 alpha ubiquitination and degradation
-
Tan M, Gu Q, He H, Pamarthy D, Semenza GL, Sun Y. SAG/ROC2/RBX2 is a HIF-1 target gene that promotes HIF-1 alpha ubiquitination and degradation. Oncogene 2008;27: 1404-11.
-
(2008)
Oncogene
, vol.27
, pp. 1404-1411
-
-
Tan, M.1
Gu, Q.2
He, H.3
Pamarthy, D.4
Semenza, G.L.5
Sun, Y.6
-
48
-
-
4344645563
-
Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases
-
Marxsen JH, Stengel P, Doege K, Heikkinen P, Jokilehto T, Wagner T, et al. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases. Biochem J 2004;381: 761-7.
-
(2004)
Biochem J
, vol.381
, pp. 761-767
-
-
Marxsen, J.H.1
Stengel, P.2
Doege, K.3
Heikkinen, P.4
Jokilehto, T.5
Wagner, T.6
-
49
-
-
38349189787
-
Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugation
-
Kim MJ, Hwang SY, Imaizumi T, Yoo JY. Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugation. J Virol 2008;82: 1474-83.
-
(2008)
J Virol
, vol.82
, pp. 1474-1483
-
-
Kim, M.J.1
Hwang, S.Y.2
Imaizumi, T.3
Yoo, J.Y.4
-
50
-
-
84865107849
-
Gene-targeting of Phd2 improves tumor response to chemotherapy and prevents side-toxicity
-
Leite de Oliveira R, Deschoemaeker S, Henze AT, Debackere K, Finisguerra V, Takeda Y, et al. Gene-targeting of Phd2 improves tumor response to chemotherapy and prevents side-toxicity. Cancer Cell 2012;22: 263-77.
-
(2012)
Cancer Cell
, vol.22
, pp. 263-277
-
-
Leite De Oliveira, R.1
Deschoemaeker, S.2
Henze, A.T.3
Debackere, K.4
Finisguerra, V.5
Takeda, Y.6
|