메뉴 건너뛰기




Volumn 195, Issue 3, 2013, Pages 1117-1128

Genetic and nongenetic variation revealed for the principal components of human gene expression

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COMPARATIVE STUDY; GENE EXPRESSION; GENETIC VARIABILITY; HUMAN; METABOLISM; OXIDATIVE PHOSPHORYLATION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; STATISTICAL MODEL;

EID: 84887036163     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.113.153221     Document Type: Article
Times cited : (17)

References (58)
  • 1
    • 0033909546 scopus 로고    scopus 로고
    • A general test of association for quantitative traits in nuclear families
    • Abecasis, G., L. Cardon, and W. Cookson, 2000 A general test of association for quantitative traits in nuclear families. Am. J. Hum. Genet. 66: 279-292.
    • (2000) Am. J. Hum. Genet , vol.66 , pp. 279-292
    • Abecasis, G.1    Cardon, L.2    Cookson, W.3
  • 2
    • 84865060986 scopus 로고    scopus 로고
    • Identifying the genetic variation of gene expression using gene sets: Application of novel gene set eQTL approach to PharmGKB and KEGG
    • Abo, R., G. D. Jenkins, L. Wang, and B. L. Fridley, 2012 Identifying the genetic variation of gene expression using gene sets: application of novel gene set eQTL approach to PharmGKB and KEGG. PLoS ONE 7: e43301.
    • (2012) PLoS ONE , vol.7
    • Abo, R.1    Jenkins, G.D.2    Wang, L.3    Fridley, B.L.4
  • 3
    • 29244448340 scopus 로고    scopus 로고
    • Microarray data analysis: From disarray to consolidation and consensus
    • Allison, D. B., X. Cui, G. P. Page, and M. Sabripour, 2006 Microarray data analysis: from disarray to consolidation and consensus. Nat. Rev. Genet. 7: 55-65.
    • (2006) Nat. Rev. Genet , vol.7 , pp. 55-65
    • Allison, D.B.1    Cui, X.2    Page, G.P.3    Sabripour, M.4
  • 4
    • 41949101394 scopus 로고    scopus 로고
    • Run batch effects potentially compromise the usefulness of genomic signatures for ovarian cancer
    • Baggerly, K. A., K. R. Coombes, and E. S. Neeley, 2008 Run batch effects potentially compromise the usefulness of genomic signatures for ovarian cancer. J. Clin. Oncol. 26: 1186-1187.
    • (2008) J. Clin. Oncol , vol.26 , pp. 1186-1187
    • Baggerly, K.A.1    Coombes, K.R.2    Neeley, E.S.3
  • 5
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y., and Y. Hochberg, 1995 Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. B 57: 289-300.
    • (1995) J. R. Stat. Soc. B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 6
    • 45249095384 scopus 로고    scopus 로고
    • Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
    • Biswas, S., J. D. Storey, and J. M. Akey, 2008 Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis. BMC Bioinformatics 9: 244.
    • (2008) BMC Bioinformatics , vol.9 , pp. 244
    • Biswas, S.1    Storey, J.D.2    Akey, J.M.3
  • 7
    • 47249097168 scopus 로고    scopus 로고
    • Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories
    • Boedigheimer, M. J., R. D. Wolfinger, M. B. Bass, P. R. Bushel, J. W. Chou et al., 2008 Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories. BMC Genomics 9: 285.
    • (2008) BMC Genomics , vol.9 , pp. 285
    • Boedigheimer, M.J.1    Wolfinger, R.D.2    Bass, M.B.3    Bushel, P.R.4    Chou, J.W.5
  • 8
    • 84887072133 scopus 로고    scopus 로고
    • Integrative modeling of eQTLs and cis-regulatory elements suggest mechanisms underlying cell type specificity of eQTLs
    • Brown, C. D., L. M. Mangravite, and B. E. Engelhardt, 2012 Integrative modeling of eQTLs and cis-regulatory elements suggest mechanisms underlying cell type specificity of eQTLs. arXiv preprint. arXiv:1210.3294.
    • (2012) ArXiv Preprint. ArXiv , vol.1210 , pp. 3294
    • Brown, C.D.1    Mangravite, L.M.2    Engelhardt, B.E.3
  • 9
    • 0030919567 scopus 로고    scopus 로고
    • Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia
    • Browne, S. E., A. C. Bowling, U. Macgarvey, M. J. Baik, S. C. Berger et al., 1997 Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia. Ann. Neurol. 41: 646-653.
    • (1997) Ann. Neurol , vol.41 , pp. 646-653
    • Browne, S.E.1    Bowling, A.C.2    Macgarvey, U.3    Baik, M.J.4    Berger, S.C.5
  • 10
    • 46749152178 scopus 로고    scopus 로고
    • A modular analysis framework for blood genomics studies: Application to systemic lupus erythematosus
    • Chaussabel, D., C. Quinn, J. Shen, P. Patel, C. Glaser et al., 2008 A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity 29: 150-164.
    • (2008) Immunity , vol.29 , pp. 150-164
    • Chaussabel, D.1    Quinn, C.2    Shen, J.3    Patel, P.4    Glaser, C.5
  • 11
    • 79952230540 scopus 로고    scopus 로고
    • Removing batch effects in analysis of expression microarray data: An evaluation of six batch adjustment methods
    • Chen, C., K. Grennan, J. Badner, D. Zhang, E. Gershon et al., 2011 Removing batch effects in analysis of expression microarray data: an evaluation of six batch adjustment methods. PLoS ONE 6: e17238.
    • (2011) PLoS ONE , vol.6
    • Chen, C.1    Grennan, K.2    Badner, J.3    Zhang, D.4    Gershon, E.5
  • 12
    • 40749105508 scopus 로고    scopus 로고
    • Variations in DNA elucidate molecular networks that cause disease
    • Chen, Y., J. Zhu, P. Y. Lum, X. Yang, S. Pinto et al., 2008 Variations in DNA elucidate molecular networks that cause disease. Nature 452: 429-435.
    • (2008) Nature , vol.452 , pp. 429-435
    • Chen, Y.1    Zhu, J.2    Lum, P.Y.3    Yang, X.4    Pinto, S.5
  • 13
    • 0036900895 scopus 로고    scopus 로고
    • Fundamentals of experimental design for cDNA microarrays
    • Churchill, G. A., 2002 Fundamentals of experimental design for cDNA microarrays. Nat. Genet. 32: 490-495.
    • (2002) Nat. Genet , vol.32 , pp. 490-495
    • Churchill, G.A.1
  • 14
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Da Wei Huang, B. T. S., and R. A. Lempicki, 2008 Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4: 44-57.
    • (2008) Nat. Protoc , vol.4 , pp. 44-57
    • Da Wei, H.B.T.S.1    Lempicki, R.A.2
  • 15
    • 80052322958 scopus 로고    scopus 로고
    • Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA
    • Fehrmann, R. S. N., R. C. Jansen, J. H. Veldink, H. J. Westra, D. Arends et al., 2011 Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet. 7: e1002197.
    • (2011) PLoS Genet , vol.7
    • Fehrmann, R.S.N.1    Jansen, R.C.2    Veldink, J.H.3    Westra, H.J.4    Arends, D.5
  • 16
    • 84857487802 scopus 로고    scopus 로고
    • Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression
    • Fu, J., M. G. M. Wolfs, P. Deelen, H. J. Westra, R. S. N. Fehrmann et al., 2012 Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet. 8: e1002431.
    • (2012) PLoS Genet , vol.8
    • Fu, J.1    Wolfs, M.G.M.2    Deelen, P.3    Westra, H.J.4    Fehrmann, R.S.N.5
  • 17
    • 59149107081 scopus 로고    scopus 로고
    • SVDbased anatomy of gene expressions for correlation analysis in Arabidopsis thaliana
    • Fukushima, A., M. Wada, S. Kanaya, and M. Arita, 2008 SVDbased anatomy of gene expressions for correlation analysis in Arabidopsis thaliana. DNA Res. 15: 367-374.
    • (2008) DNA Res , vol.15 , pp. 367-374
    • Fukushima, A.1    Wada, M.2    Kanaya, S.3    Arita, M.4
  • 18
    • 0020360096 scopus 로고
    • Noise reduction by eigenvector ordinations
    • Gauch, H. G., Jr., 1982 Noise reduction by eigenvector ordinations. Ecology 63: 1643-1649.
    • (1982) Ecology , vol.63 , pp. 1643-1649
    • Gauch Jr., H.G.1
  • 19
    • 33747738463 scopus 로고
    • Singular value decomposition and least squares solutions
    • Golub, G. H., and C. Reinsch, 1970 Singular value decomposition and least squares solutions. Numerische Mathematik 14: 403-420.
    • (1970) Numerische Mathematik , vol.14 , pp. 403-420
    • Golub, G.H.1    Reinsch, C.2
  • 20
    • 84866871814 scopus 로고    scopus 로고
    • Mapping cis-and trans-regulatory effects across multiple tissues in twins
    • Grundberg, E., K. S. Small, Å. K. Hedman, A. C. Nica, A. Buil et al., 2012 Mapping cis-and trans-regulatory effects across multiple tissues in twins. Nat. Genet. 44: 1084-1089.
    • (2012) Nat. Genet , vol.44 , pp. 1084-1089
    • Grundberg, E.1    Small, K.S.2    Hedman Å., K.3    Nica, A.C.4    Buil, A.5
  • 21
    • 34547526914 scopus 로고    scopus 로고
    • Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis
    • Hirai, M. Y., K. Sugiyama, Y. Sawada, T. Tohge, T. Obayashi et al., 2007 Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis. Proc. Natl. Acad. Sci. USA 104: 6478-6483.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 6478-6483
    • Hirai, M.Y.1    Sugiyama, K.2    Sawada, Y.3    Tohge, T.4    Obayashi, T.5
  • 22
    • 0034682504 scopus 로고    scopus 로고
    • Fundamental patterns underlying gene expression profiles: Simplicity from complexity
    • Holter, N. S., M. Mitra, A. Maritan, M. Cieplak, J. R. Banavar et al., 2000 Fundamental patterns underlying gene expression profiles: simplicity from complexity. Proc. Natl. Acad. Sci. USA 97: 8409-8414.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8409-8414
    • Holter, N.S.1    Mitra, M.2    Maritan, A.3    Cieplak, M.4    Banavar, J.R.5
  • 23
    • 0026781603 scopus 로고
    • Oxidative energy metabolism in Alzheimer brain
    • Hoyer, S., 1992 Oxidative energy metabolism in Alzheimer brain. Mol. Chem. Neuropathol. 16: 207-224.
    • (1992) Mol. Chem. Neuropathol , vol.16 , pp. 207-224
    • Hoyer, S.1
  • 24
    • 0346095291 scopus 로고    scopus 로고
    • Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae
    • Ihmels, J., R. Levy, and N. Barkai, 2003 Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae. Nat. Biotechnol. 22: 86-92.
    • (2003) Nat. Biotechnol , vol.22 , pp. 86-92
    • Ihmels, J.1    Levy, R.2    Barkai, N.3
  • 27
    • 84864471159 scopus 로고    scopus 로고
    • A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
    • Jonsson, T., J. K. Atwal, S. Steinberg, J. Snaedal, P. V. Jonsson et al., 2012 A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature 488: 96-99.
    • (2012) Nature , vol.488 , pp. 96-99
    • Jonsson, T.1    Atwal, J.K.2    Steinberg, S.3    Snaedal, J.4    Jonsson, P.V.5
  • 28
    • 34848914038 scopus 로고    scopus 로고
    • Capturing heterogeneity in gene expression studies by surrogate variable analysis
    • Leek, J. T., and J. D. Storey, 2007 Capturing heterogeneity in gene expression studies by surrogate variable analysis. PLoS Genet. 3: e161.
    • (2007) PLoS Genet , vol.3
    • Leek, J.T.1    Storey, J.D.2
  • 29
    • 77956873627 scopus 로고    scopus 로고
    • Tackling the widespread and critical impact of batch effects in high-throughput data
    • Leek, J. T., R. B. Scharpf, H. C. Bravo, D. Simcha, B. Langmead et al., 2010 Tackling the widespread and critical impact of batch effects in high-throughput data. Nat. Rev. Genet. 11: 733-739.
    • (2010) Nat. Rev. Genet , vol.11 , pp. 733-739
    • Leek, J.T.1    Scharpf, R.B.2    Bravo, H.C.3    Simcha, D.4    Langmead, B.5
  • 30
    • 33845432928 scopus 로고    scopus 로고
    • Adjusting batch effects in microarray expression data using empirical Bayes methods
    • Li, C., and A. Rabinovic, 2007 Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics 8: 118-127.
    • (2007) Biostatistics , vol.8 , pp. 118-127
    • Li, C.1    Rabinovic, A.2
  • 32
    • 84867667046 scopus 로고    scopus 로고
    • Genetic association analysis of complex diseases incorporating intermediate phenotype information
    • Li, Y., J. Huang, and C. I. Amos, 2012 Genetic association analysis of complex diseases incorporating intermediate phenotype information. PLoS ONE 7: e46612.
    • (2012) PLoS ONE , vol.7
    • Li, Y.1    Huang, J.2    Amos, C.I.3
  • 33
    • 77955131271 scopus 로고    scopus 로고
    • A comparison of batch effect removal methods for enhancement of prediction performance using MAQC-II microarray gene expression data
    • Luo, J., M. Schumacher, A. Scherer, D. Sanoudou, D. Megherbi et al., 2010 A comparison of batch effect removal methods for enhancement of prediction performance using MAQC-II microarray gene expression data. Pharmacogenomics J. 10: 278-291.
    • (2010) Pharmacogenomics J , vol.10 , pp. 278-291
    • Luo, J.1    Schumacher, M.2    Scherer, A.3    Sanoudou, D.4    Megherbi, D.5
  • 35
    • 63549098588 scopus 로고    scopus 로고
    • Identification of differential gene pathways with principal component analysis
    • Ma, S., and M. R. Kosorok, 2009 Identification of differential gene pathways with principal component analysis. Bioinformatics 25: 882-889.
    • (2009) Bioinformatics , vol.25 , pp. 882-889
    • Ma, S.1    Kosorok, M.R.2
  • 36
    • 0028152717 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
    • Mecocci, P., U. MacGarvey, and M. F. Beal, 2004 Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann. Neurol. 36: 747-751.
    • (2004) Ann. Neurol , vol.36 , pp. 747-751
    • Mecocci, P.1    Macgarvey, U.2    Beal, M.F.3
  • 37
    • 0036069214 scopus 로고    scopus 로고
    • Interactive exploration of microarray gene expression patterns in a reduced dimensional space
    • Misra, J., W. Schmitt, D. Hwang, L. L. Hsiao, S. Gullans et al., 2002 Interactive exploration of microarray gene expression patterns in a reduced dimensional space. Genome Res. 12: 1112-1120.
    • (2002) Genome Res , vol.12 , pp. 1112-1120
    • Misra, J.1    Schmitt, W.2    Hwang, D.3    Hsiao, L.L.4    Gullans, S.5
  • 38
    • 84876007294 scopus 로고    scopus 로고
    • Using blood informative transcripts in geographical genomics: Impact of lifestyle on gene expression in Fijians
    • Nath, A. P., D. Arafat, and G. Gibson, 2012 Using blood informative transcripts in geographical genomics: impact of lifestyle on gene expression in Fijians. Front. Genet. 3: 243.
    • (2012) Front. Genet , vol.3 , pp. 243
    • Nath, A.P.1    Arafat, D.2    Gibson, G.3
  • 39
    • 58149330480 scopus 로고    scopus 로고
    • Using gene expression to investigate the genetic basis of complex disorders
    • Nica, A. C., and E. T. Dermitzakis, 2008 Using gene expression to investigate the genetic basis of complex disorders. Hum. Mol. Genet. 17: R129-R134.
    • (2008) Hum. Mol. Genet , vol.17
    • Nica, A.C.1    Dermitzakis, E.T.2
  • 40
    • 77954133026 scopus 로고    scopus 로고
    • Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
    • Park, J. H., S. Wacholder, M. H. Gail, U. Peters, K. B. Jacobs et al., 2010 Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat. Genet. 42: 570-575.
    • (2010) Nat. Genet , vol.42 , pp. 570-575
    • Park, J.H.1    Wacholder, S.2    Gail, M.H.3    Peters, U.4    Jacobs, K.B.5
  • 41
    • 84863641258 scopus 로고    scopus 로고
    • Extent, causes, and consequences of small RNA expression variation in human adipose tissue
    • Parts, L., Å. K. Hedman, S. Keildson, A. J. Knights, C. Abreu-Goodger et al., 2012 Extent, causes, and consequences of small RNA expression variation in human adipose tissue. PLoS Genet. 8: e1002704.
    • (2012) PLoS Genet , vol.8
    • Parts, L.1    Hedman Å., K.2    Keildson, S.3    Knights, A.J.4    Abreu-Goodger, C.5
  • 42
    • 19044395321 scopus 로고    scopus 로고
    • How many principal components? Stopping rules for determining the number of non-trivial axes revisited
    • Peres-Neto, P. R., D. A. Jackson, and K. M. Somers, 2005 How many principal components? Stopping rules for determining the number of non-trivial axes revisited. Comput. Stat. Data Anal. 49: 974-997.
    • (2005) Comput. Stat. Data Anal , vol.49 , pp. 974-997
    • Peres-Neto, P.R.1    Jackson, D.A.2    Somers, K.M.3
  • 43
    • 77950460661 scopus 로고    scopus 로고
    • Understanding mechanisms underlying human gene expression variation with RNA sequencing
    • Pickrell, J. K., J. C. Marioni, A. A. Pai, J. F. Degner, B. E. Engelhardt et al., 2010 Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature 464: 768-772.
    • (2010) Nature , vol.464 , pp. 768-772
    • Pickrell, J.K.1    Marioni, J.C.2    Pai, A.A.3    Degner, J.F.4    Engelhardt, B.E.5
  • 44
    • 84860372128 scopus 로고    scopus 로고
    • The Brisbane Systems Genetics Study: Genetical genomics meets complex trait genetics
    • Powell, J. E., A. K. Henders, A. F. McRae, A. Caracella, S. Smith et al., 2012a The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics. PLoS ONE 7: e35430.
    • (2012) PLoS ONE , vol.7
    • Powell, J.E.1    Henders, A.K.2    McRae, A.F.3    Caracella, A.4    Smith, S.5
  • 45
    • 84857856577 scopus 로고    scopus 로고
    • Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent
    • Powell, J. E., A. K. Henders, A. F. McRae, M. J. Wright, N. G. Martin et al., 2012b Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent. Genome Res. 22: 456-466.
    • (2012) Genome Res , vol.22 , pp. 456-466
    • Powell, J.E.1    Henders, A.K.2    McRae, A.F.3    Wright, M.J.4    Martin, N.G.5
  • 46
    • 79952263851 scopus 로고    scopus 로고
    • Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals
    • Price, A. L., A. Helgason, G. Thorleifsson, S. A. McCarroll, A. Kong et al., 2011 Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals. PLoS Genet. 7: e1001317.
    • (2011) PLoS Genet , vol.7
    • Price, A.L.1    Helgason, A.2    Thorleifsson, G.3    McCarroll, S.A.4    Kong, A.5
  • 47
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell, S., B. Neale, K. Todd-Brown, L. Thomas, M. A. R. Ferreira et al., 2007 PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81: 559-575.
    • (2007) Am. J. Hum. Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.R.5
  • 48
    • 84875999789 scopus 로고    scopus 로고
    • Effect of normalization on statistical and biological interpretation of gene expression profiles
    • Qin, S. P., J. Kim, D. Arafat, and G. Gibson, 2012 Effect of normalization on statistical and biological interpretation of gene expression profiles. Front. Genet. 3: 160.
    • (2012) Front. Genet , vol.3 , pp. 160
    • Qin, S.P.1    Kim, J.2    Arafat, D.3    Gibson, G.4
  • 49
    • 0033657261 scopus 로고    scopus 로고
    • Principal components analysis to summarize microarray experiments: Application to sporulation time series
    • Raychaudhuri, S., J. M. Stuart, and R. B. Altman, 2000 Principal components analysis to summarize microarray experiments: application to sporulation time series. Pac. Symp. Biocomput. 2000: 455-466.
    • (2000) Pac. Symp. Biocomput , pp. 455-466
    • Raychaudhuri, S.1    Stuart, J.M.2    Altman, R.B.3
  • 50
    • 73949142307 scopus 로고    scopus 로고
    • Amyloid-b and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice
    • Rhein, V., X. Song, A. Wiesner, L. M. Ittner, G. Baysang et al., 2009 Amyloid-b and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proc. Natl. Acad. Sci. USA 106: 20057-20062.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 20057-20062
    • Rhein, V.1    Song, X.2    Wiesner, A.3    Ittner, L.M.4    Baysang, G.5
  • 52
    • 34547589578 scopus 로고    scopus 로고
    • DAVID Bioinformatics Resources: Expanded annotation database and novel algorithms to better extract biology from large gene lists
    • Sherman, B. T., Q. Tan, J. Kir, D. Liu, D. Bryant et al., 2007 DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res. 35: W169-W175.
    • (2007) Nucleic Acids Res , vol.35
    • Sherman, B.T.1    Tan, Q.2    Kir, J.3    Liu, D.4    Bryant, D.5
  • 53
    • 34347341673 scopus 로고    scopus 로고
    • Reply to On the design and analysis of gene expression studies in human populations
    • Spielman, R. S., and V. G. Cheung, 2007 Reply to "On the design and analysis of gene expression studies in human populations". Nat. Genet. 39: 808-809.
    • (2007) Nat. Genet , vol.39 , pp. 808-809
    • Spielman, R.S.1    Cheung, V.G.2
  • 54
    • 47249132988 scopus 로고    scopus 로고
    • Accounting for non-genetic factors improves the power of eQTL studies
    • Springer, Berlin, Germany/New York
    • Stegle, O., A. Kannan, R. Durbin, and J. Winn, 2008 Accounting for non-genetic factors improves the power of eQTL studies, pp. 411-422 in Research in Computational Molecular Biology. Springer, Berlin, Germany/New York.
    • (2008) Research In Computational Molecular Biology , pp. 411-422
    • Stegle, O.1    Kannan, A.2    Durbin, R.3    Winn, J.4
  • 55
    • 77955505742 scopus 로고    scopus 로고
    • A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies
    • Stegle, O., L. Parts, R. Durbin, and J. Winn, 2010 A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies. PLOS Comput. Biol. 6: e1000770.
    • (2010) PLOS Comput. Biol , vol.6
    • Stegle, O.1    Parts, L.2    Durbin, R.3    Winn, J.4
  • 57
    • 0041336612 scopus 로고    scopus 로고
    • Effects of atmospheric ozone on microarray data quality
    • Thomas, L., E. M. Coffey, H. Dai, Y. D. He, D. A. Kessler et al., 2003 Effects of atmospheric ozone on microarray data quality. Anal. Chem. 75: 4672-4675.
    • (2003) Anal. Chem , vol.75 , pp. 4672-4675
    • Thomas, L.1    Coffey, E.M.2    Dai, H.3    He, Y.D.4    Kessler, D.A.5
  • 58
    • 0034800371 scopus 로고    scopus 로고
    • Principal component analysis for clustering gene expression data
    • Yeung, K. Y., and W. L. Ruzzo, 2001 Principal component analysis for clustering gene expression data. Bioinformatics 17: 763-774.
    • (2001) Bioinformatics , vol.17 , pp. 763-774
    • Yeung, K.Y.1    Ruzzo, W.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.