Phosphorescent iridium(III) complexes as multicolor probes for specific mitochondrial imaging and tracking

Biomaterials

Volumn 35, Issue 1, 2014, Pages 2-13

  Chen, Yu ^a   Qiao, Liping ^a   Ji, Liangnian ^a   Chao, Hui ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Imaging; Iridium(III) complex; Mitochondria; Phosphorescence; Probe; Tracking

Indexed keywords

ENVIRONMENTAL CHANGE; HIGH SPECIFICITY; IRIDIUM COMPLEX; MEMBRANE PERMEABILIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL MORPHOLOGY; MORPHOLOGICAL CHANGES; TUNABLE EMISSIONS;

IMAGING TECHNIQUES; LIGHT EMISSION; PHOSPHORESCENCE; PROBES; SURFACE DISCHARGES;

MITOCHONDRIA;

IRIDIUM COMPLEX; QUINOXALINE;

ARTICLE; COLOR; ENVIRONMENTAL CHANGE; IMAGING; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PHOSPHORESCENCE; PRIORITY JOURNAL;

IMAGING; IRIDIUM(III) COMPLEX; MITOCHONDRIA; PHOSPHORESCENCE; PROBE; TRACKING;

COLOR; CRYSTALLOGRAPHY, X-RAY; HELA CELLS; HUMANS; IRIDIUM; MAGNETIC RESONANCE SPECTROSCOPY; MITOCHONDRIA; MOLECULAR PROBES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84887026200     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.09.051     Document Type: Article

References (43)

1. Henze K., Martin W. Essence of mitochondria. Nature 2002, 426:127-128.
2. McBride H.M., Neuspiel M., Wasiak S. Mitochondria: more than just a powerhouse. Curr Biol 2006, 16:R551-R560.
3. Green D.R. Apoptotic pathways: the roads to ruin. Cell 1998, 94:695-698.
4. Mammucari C., Rizzuto R. Signaling pathways in mitochondrial dysfunction and aging. Mech Ageing Dev 2010, 131:536-543.
5. Dickinson B.C., Srikun D., Chang C.J. Mitochondrial-targeted fluorescent probes for reactive oxygen species. Curr Opin Chem Biol 2010, 14:50-56.
6. Lee J., Giordano S., Zhang J. Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling. Biochem J 2012, 441:523-540.
7. Wang Y.Q., Nartiss Y., Steipe B., McQuibban G.A., Kim P.K. ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy. Autophagy 2012, 8:1462-1476.
8. Youle R.J., Narendra D.P. Mechanisms of mitophagy. Nat Rev Mol Cell Biol 2011, 12:9-14.
9. Santos R.X., Correia S.C., Wang X., Perry G., Smith M.A., Moreira P.I., et al. Asynergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease. JAlzheimers Dis 2010, 20(Suppl.2):S401-S412.
10. Masanta G., Heo C.H., Lim C.S., Bae S.K., Cho B.R., Kim H.M. Amitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue. Chem Commun 2012, 48:3518-3520.
11. Mitra K., Lippincott-Schwartz J. Analysis of mitochondrial dynamics and functions using imaging aApproaches. Curr Protoc Cell Biol 2010, 46:4.25.1-4.25.21.
12. Karbowski M., Youle R.J. Dynamics of mitochondrial morphology in healthy cells and during apoptosis. Cell Death Differ 2003, 10:870-880.
13. Yang H., Ding L., An L., Xiang Z.Y., Chen M., Zhou J., et al. Ad-f heteronuclear complex for dual-mode phosphorescence and magnetic resonance imaging. Biomaterials 2012, 33:8591-8599.
14. MitoTracker® mitochondrion-sSelective probes. Invitrogen. http://tools.invitrogen.com/content/sfs/manuals/mp07510.pdf.
15. Leung C.W.T., Hong Y.N., Chen S.J., Zhao E.G., Lam J.W.Y., Tang B.Z. Aphotostable AIE luminogen for specific mitochondrial imaging. JAm Soc Chem 2013, 135:62-65.
16. 6 transition metal complexes in fluorescence cell imaging. Chem Commun 2010, 46:186-202.
17. III complexes and their applications. Adv Mater 2010, 22:1534-1539.
18. Yang Y.M., Zhao Q., Feng W., Li F.Y. Luminescent chemodosimeters for bioimaging. Chem Rev 2013, 113:192-270.
19. Zhao Q., Huang C.H., Li F.Y. Phosphorescent heavy-metal complexes for bioimaging. Chem Soc Rev 2011, 40:2508-2524.
20. Wang X.B., Jia J.L., Huang Z.Z., Zhou M., Fei H. Luminescent peptide labeling based on a histidine-binding iridium(III) complex for cell penetration and intracellular targeting studies. Chem Eur J 2011, 17:8028-8032.
21. Duan J.P., Sun P.P., Cheng C.H. New iridium complexes as highly efficient orange-red emitters in organic ligh-emitting diodes. Adv Mater 2003, 15:224-228.
22. Sun D.D., Liu Y.N., Yu Q.Q., Zhou Y.H., Zhang R., Chen X.J., et al. The effects of luminescent ruthenium(II) polypyridyl functionalized selenium nanoparticles on bFGF-induced angiogenesis and AKT/ERK signaling. Biomaterials 2013, 34:171-180.
23. Li C.Y., Liu Y., Wu Y.Q., Sun Y., Li F.Y. The cellular uptake and localization of non-emissive iridium(III) complexes as cellular reaction-based luminescence probes. Biomaterials 2013, 34:1223-1234.
24. Ma D.L., Wong W.L., Chung W.H., Chan F.Y., So P.K., Lai T.S., et al. Ahighly selective luminescent switch-on probe for histidine/histidine-rich proteins and its application in protein staining. Angew Chem Int Ed 2008, 47:3735-3739.
25. Nonoyama M. Benzo[H]quinolin-10-Yl-N iridium (III) complexes. BChem Soc Jpn 1974, 47:767-768.
26. Schmid B., Garces F.O., Watts R.J. Synthesis and characterizations of cyclometalated iridium(III) solvent complexes. Biochemistry 1994, 33:9-14.
27. Blessing R. An empirical correction for absorption anisotropy. Acta Crystallogr Sect A 1995, 51:33-38.
28. Sheldrick G.M. SHELXS 97, program for X-ray crystal structure determination 1997, University of Göttingen, SHELXL-97, Program for X-Ray Crystal Structure Refinement, University of Göttingen, 1997.
29. Egger A.E., Rappel C., Jakupec M.A., Hartinger C.G., Heffeter P., Keppler B.K. Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells. JAnal Spectrom 2009, 24:51-61.
30. Li Q., Sun D.D., Zhou Y.H., Liu D., Zhang Q.L., Liu J. Anticancer activity of novel ruthenium complex with 1,10-phenanthrolineselenazole as potent telomeric G-quadruplex inhibitor. Inorg Chem Commun 2012, 20:142-146.
31. Hwang A.R., Han W.S., Wee K.R., Kim H.Y., Cho D.W., Min B.K., et al. Photodynamic behavior of heteroleptic Ir(III) complexes with carbazole-functionalized dendrons associated with efficient electron transfer processes. JPhys Chem C 2012, 116:1973-1986.
32. Neve F., Deda M.L., Crispini A., Bellusci A., Puntoriero F., Campagma S. Cationic cyclometalated iridium luminophores: photophysical, redox, and structural characterization. Organometallics 2004, 23:5856-5863.
33. Serroni S., Juris A., Campagna S., Venturi M., Denti G., Balzani V. Tetranuclear bimetallic complexes of ruthenium, osmium, rhodium, and iridium. Synthesis, absorption spectra, luminescence, and electrochemical properties. JAm Chem Soc 1994, 116:9086-9091.
34. Zhao Q., Yu M.X., Shi L.X., Liu S.J., Li C.Y., Shi M., et al. Cationic iridium(III) complexes with tunable emission color as phosphorescent dyes for live cell imaging. Organometallics 2010, 29:1085-1091.
35. Zhao Q., Liu S.J., Shi M., Wang C.M., Yu M.X., Li L., et al. Series of new cationic Iridium(III) complexes with tunable emission wavelength and excited state properties: structures, theoretical calculations, and photophysical and electrochemical properties. Inorg Chem 2006, 45:6152-6160.
36. Puckett C.A., Barton J.K. Mechanism of cellular uptake of a ruthenium polypyridyl complex. Biochemistry 2008, 47:11711-11716.
37. Zhang K.Y., Liu H.W., Fong T.T.H., Chen X.G., Lo K.K.W. Luminescent dendritic cyclometalated iridium(III) polypyridine complexes: synthesis, emission behavior, and biological properties. Inorg Chem 2010, 49:5432-5443.
38. Gratton S.E.A., Ropp P.A., Pohlhaus P.D., Luft J.C., Madden V.J., Napier M.E., et al. The effect of particle design on cellular internalization pathways. PNAS 2008, 105:11613-11618.
39. Nishikawa T., Edelstein D., Du X.L., Yamagishi S., Matsumura T., Kaneda Y., et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000, 404:787-790.
40. Gomesa L.C., Scorrano L. Mitochondrial morphology in mitophagy and macroautophagy. BBA Mol Cell Res 2013, 1833:205-212.
41. Ong S.B., Hall A.R., Hausenloy D.J. Mitochondrial dynamics in cardiovascular health and disease. Antioxid Redox Signal 2013, 19:400-414.
42. Galloway C.A., Yoon Y. Mitochondrial morphology in metabolic diseases. Antioxid Redox Signal 2013, 19:415-430.
43. Reis Y., Bernardo-Faura M., Richter D., Wolf T., Brors B., Hamacher-Brady A., et al. Multi-parametric analysis and modeling of relationships between mitochondrial morphology and apoptosis. PLoS ONE 2012, 7:e28694.