메뉴 건너뛰기




Volumn 87, Issue 20, 2013, Pages 10955-10967

A respiratory syncytial virus (RSV) Anti-G protein F(ab')2 monoclonal antibody suppresses mucous production and breathing effort in RSV rA2-line19F-infected BALB/c mice

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; IMMUNOGLOBULIN F(AB')2 FRAGMENT; MONOCLONAL ANTIBODY 131 2G; MUCIN; SUBSTANCE P; UNCLASSIFIED DRUG;

EID: 84886921793     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01164-13     Document Type: Article
Times cited : (58)

References (78)
  • 3
    • 0031683919 scopus 로고    scopus 로고
    • Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants
    • IMpact-RSV Study Group
    • IMpact-RSV Study Group. 1998. Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. Pediatrics 102:531-537.
    • (1998) Pediatrics , vol.102 , pp. 531-537
  • 4
    • 84860343998 scopus 로고    scopus 로고
    • Antibodies for prevention and treatment of respiratory syncytial virus infections in children
    • Geevarghese B, Simões EA. 2012. Antibodies for prevention and treatment of respiratory syncytial virus infections in children. Antivir. Ther. 17:201-211.
    • (2012) Antivir. Ther. , vol.17 , pp. 201-211
    • Geevarghese, B.1    Simões, E.A.2
  • 5
    • 36749097325 scopus 로고    scopus 로고
    • 2007 Guideline for isolation precautions: preventing transmission of infectious agents in health care settings
    • Siegel JD, Rhinehart E, Jackson M, Chiarello L. 2007. 2007 Guideline for isolation precautions: preventing transmission of infectious agents in health care settings. Am. J. Infect. Control 35(Suppl 2):S65-S164.
    • (2007) Am. J. Infect. Control , vol.35 , Issue.SUPPL. 2
    • Siegel, J.D.1    Rhinehart, E.2    Jackson, M.3    Chiarello, L.4
  • 6
    • 81555228664 scopus 로고    scopus 로고
    • Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years
    • Collins PL, Melero JA. 2011. Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years. Virus Res. 162: 80-99.
    • (2011) Virus Res. , vol.162 , pp. 80-99
    • Collins, P.L.1    Melero, J.A.2
  • 7
    • 78650566298 scopus 로고    scopus 로고
    • Biological challenges and technological opportunities for respiratory syncytial virus vaccine development
    • Graham BS. 2011. Biological challenges and technological opportunities for respiratory syncytial virus vaccine development. Immunol. Rev. 239: 149-166.
    • (2011) Immunol. Rev. , vol.239 , pp. 149-166
    • Graham, B.S.1
  • 8
    • 0025973901 scopus 로고
    • Respiratory syncytial virus (RSV) F, G, M2 (22K), and N proteins each induce resistance to RSV challenge, but resistance induced by M2 and N proteins is relatively short-lived
    • Connors M, Collins PL, Firestone CY, Murphy BR. 1991. Respiratory syncytial virus (RSV) F, G, M2 (22K), and N proteins each induce resistance to RSV challenge, but resistance induced by M2 and N proteins is relatively short-lived. J. Virol. 65:1634-1637.
    • (1991) J. Virol. , vol.65 , pp. 1634-1637
    • Connors, M.1    Collins, P.L.2    Firestone, C.Y.3    Murphy, B.R.4
  • 9
    • 0011821905 scopus 로고
    • Expression of the F glycoprotein of respiratory syncytial virus by a recombinant vaccinia virus: comparison of the individual contributions of the F and G glycoproteins to host immunity
    • Olmsted RA, Elango N, Prince GA, Murphy BR, Johnson PR, Moss B, Chanock RM, Collins PL. 1986. Expression of the F glycoprotein of respiratory syncytial virus by a recombinant vaccinia virus: comparison of the individual contributions of the F and G glycoproteins to host immunity. Proc. Natl. Acad. Sci. U. S. A. 83:7462-7466.
    • (1986) Proc. Natl. Acad. Sci. U. S. A. , vol.83 , pp. 7462-7466
    • Olmsted, R.A.1    Elango, N.2    Prince, G.A.3    Murphy, B.R.4    Johnson, P.R.5    Moss, B.6    Chanock, R.M.7    Collins, P.L.8
  • 10
    • 0023472907 scopus 로고
    • Immune and histopathological responses in animals vaccinated with recombinant vaccinia viruses that express individual genes of human respiratory syncytial virus
    • Stott EJ, Taylor G, Ball LA, Anderson K, Young KK, King AM, Wertz GW. 1987. Immune and histopathological responses in animals vaccinated with recombinant vaccinia viruses that express individual genes of human respiratory syncytial virus. J. Virol. 61:3855-3861.
    • (1987) J. Virol. , vol.61 , pp. 3855-3861
    • Stott, E.J.1    Taylor, G.2    Ball, L.A.3    Anderson, K.4    Young, K.K.5    King, A.M.6    Wertz, G.W.7
  • 11
    • 3042852613 scopus 로고    scopus 로고
    • Pathogenesis of respiratory syncytial virus infection
    • Tripp RA. 2004. Pathogenesis of respiratory syncytial virus infection. Viral Immunol. 17:165-181.
    • (2004) Viral Immunol. , vol.17 , pp. 165-181
    • Tripp, R.A.1
  • 12
    • 0032816155 scopus 로고    scopus 로고
    • Respiratory syncytial virus G and/or SH protein alters Th1 cytokines, natural killer cells, and neutrophils responding to pulmonary infection in BALB/c mice
    • Tripp RA, Moore D, Jones L, Sullender W, Winter J, Anderson LJ. 1999. Respiratory syncytial virus G and/or SH protein alters Th1 cytokines, natural killer cells, and neutrophils responding to pulmonary infection in BALB/c mice. J. Virol. 73:7099-7107.
    • (1999) J. Virol. , vol.73 , pp. 7099-7107
    • Tripp, R.A.1    Moore, D.2    Jones, L.3    Sullender, W.4    Winter, J.5    Anderson, L.J.6
  • 13
    • 0034044265 scopus 로고    scopus 로고
    • Respiratory syncytial virus G and/or SH glycoproteins modify CC and CXC chemokine mRNA expression in the BALB/c mouse
    • Tripp RA, Jones L, Anderson LJ. 2000. Respiratory syncytial virus G and/or SH glycoproteins modify CC and CXC chemokine mRNA expression in the BALB/c mouse. J. Virol. 74:6227-6229.
    • (2000) J. Virol. , vol.74 , pp. 6227-6229
    • Tripp, R.A.1    Jones, L.2    Anderson, L.J.3
  • 14
    • 0141793845 scopus 로고    scopus 로고
    • Enhanced disease and pulmonary eosinophilia associated with formalininactivated respiratory syncytial virus vaccination are linked to G glycoprotein CX3C-CX3CR1 interaction and expression of substance
    • Haynes LM, Jones LP, Barskey A, Anderson LJ, Tripp RA. 2003. Enhanced disease and pulmonary eosinophilia associated with formalininactivated respiratory syncytial virus vaccination are linked to G glycoprotein CX3C-CX3CR1 interaction and expression of substance. P. J. Virol. 77:9831-9844.
    • (2003) P. J. Virol. , vol.77 , pp. 9831-9844
    • Haynes, L.M.1    Jones, L.P.2    Barskey, A.3    Anderson, L.J.4    Tripp, R.A.5
  • 15
    • 0033920379 scopus 로고    scopus 로고
    • Respiratory syncytial virus infection and G and/or SH protein expression contribute to substance P, which mediates inflammation and enhanced pulmonary disease in BALB/c mice
    • Tripp RA, Moore D, Winter J, Anderson LJ. 2000. Respiratory syncytial virus infection and G and/or SH protein expression contribute to substance P, which mediates inflammation and enhanced pulmonary disease in BALB/c mice. J. Virol. 74:1614-1622.
    • (2000) J. Virol. , vol.74 , pp. 1614-1622
    • Tripp, R.A.1    Moore, D.2    Winter, J.3    Anderson, L.J.4
  • 16
    • 0038364167 scopus 로고    scopus 로고
    • The G glycoprotein of respiratory syncytial virus depresses respiratory rates through the CX3C motif and substance
    • Tripp RA, Dakhama A, Jones LP, Barskey A, Gelfand EW, Anderson LJ. 2003. The G glycoprotein of respiratory syncytial virus depresses respiratory rates through the CX3C motif and substance. P. J. Virol. 77:6580-6584.
    • (2003) P. J. Virol. , vol.77 , pp. 6580-6584
    • Tripp, R.A.1    Dakhama, A.2    Jones, L.P.3    Barskey, A.4    Gelfand, E.W.5    Anderson, L.J.6
  • 19
    • 0022625904 scopus 로고
    • Identification of epitopes on respiratory syncytial virus proteins by competitive binding immunoassay
    • Anderson LJ, Hierholzer JC, Stone YO, Tsou C, Fernie BF. 1986. Identification of epitopes on respiratory syncytial virus proteins by competitive binding immunoassay. J. Clin. Microbiol. 23:475-480.
    • (1986) J. Clin. Microbiol. , vol.23 , pp. 475-480
    • Anderson, L.J.1    Hierholzer, J.C.2    Stone, Y.O.3    Tsou, C.4    Fernie, B.F.5
  • 20
    • 0023707741 scopus 로고
    • Neutralization of respiratory syncytial virus by individual and mixtures of F and G protein monoclonal antibodies
    • Anderson LJ, Bingham P, Hierholzer JC. 1988. Neutralization of respiratory syncytial virus by individual and mixtures of F and G protein monoclonal antibodies. J. Virol. 62:4232-4238.
    • (1988) J. Virol. , vol.62 , pp. 4232-4238
    • Anderson, L.J.1    Bingham, P.2    Hierholzer, J.C.3
  • 21
    • 67650690925 scopus 로고    scopus 로고
    • Therapeutic monoclonal antibody treatment targeting respiratory syncytial virus (RSV) G protein mediates viral clearance and reduces the pathogenesis of RSV infection in BALB/c mice
    • Haynes LM, Caidi H, Radu GU, Miao C, Harcourt JL, Tripp RA, Anderson LJ. 2009. Therapeutic monoclonal antibody treatment targeting respiratory syncytial virus (RSV) G protein mediates viral clearance and reduces the pathogenesis of RSV infection in BALB/c mice. J. Infect. Dis. 200:439-447.
    • (2009) J. Infect. Dis. , vol.200 , pp. 439-447
    • Haynes, L.M.1    Caidi, H.2    Radu, G.U.3    Miao, C.4    Harcourt, J.L.5    Tripp, R.A.6    Anderson, L.J.7
  • 23
    • 77956018092 scopus 로고    scopus 로고
    • Prophylactic treatment with a G glycoprotein monoclonal antibody reduces pulmonary inflammation in respiratory syncytial virus (RSV)- challenged naive and formalin-inactivated RSV-immunized BALB/c mice
    • Radu GU, Caidi H, Miao C, Tripp RA, Anderson LJ, Haynes LM. 2010. Prophylactic treatment with a G glycoprotein monoclonal antibody reduces pulmonary inflammation in respiratory syncytial virus (RSV)- challenged naive and formalin-inactivated RSV-immunized BALB/c mice. J. Virol. 84:9632-9636.
    • (2010) J. Virol. , vol.84 , pp. 9632-9636
    • Radu, G.U.1    Caidi, H.2    Miao, C.3    Tripp, R.A.4    Anderson, L.J.5    Haynes, L.M.6
  • 24
  • 26
    • 0037393323 scopus 로고    scopus 로고
    • IL-13 receptors and signaling pathways: an evolving web
    • Hershey GK. 2003. IL-13 receptors and signaling pathways: an evolving web. J. Allergy Clin. Immunol. 111:677-690.
    • (2003) J. Allergy Clin. Immunol. , vol.111 , pp. 677-690
    • Hershey, G.K.1
  • 28
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA. 1999. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J. Clin. Invest. 103:779-788.
    • (1999) J. Clin. Invest. , vol.103 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6    Zhang, Y.7    Elias, J.A.8
  • 30
    • 0027448007 scopus 로고
    • Pathogenesis and treatment of bronchiolitis
    • Lugo RA, Nahata MC. 1993. Pathogenesis and treatment of bronchiolitis. Clin. Pharm. 12:95-116.
    • (1993) Clin. Pharm. , vol.12 , pp. 95-116
    • Lugo, R.A.1    Nahata, M.C.2
  • 31
    • 0021790147 scopus 로고
    • Lobar collapse with respiratory syncytial virus pneumonitis
    • Quinn SF, Erickson S, Oshman D, Hayden F. 1985. Lobar collapse with respiratory syncytial virus pneumonitis. Pediatr. Radiol. 15:229-230.
    • (1985) Pediatr. Radiol. , vol.15 , pp. 229-230
    • Quinn, S.F.1    Erickson, S.2    Oshman, D.3    Hayden, F.4
  • 33
    • 33749256261 scopus 로고    scopus 로고
    • Respiratory syncytial virus disease mechanisms implicated by human, animal model, and in vitro data facilitate vaccine strategies and new therapeutics
    • Moore ML, Peebles RS, Jr. 2006. Respiratory syncytial virus disease mechanisms implicated by human, animal model, and in vitro data facilitate vaccine strategies and new therapeutics. Pharmacol. Ther. 112:405-424.
    • (2006) Pharmacol. Ther. , vol.112 , pp. 405-424
    • Moore, M.L.1    Peebles Jr., R.S.2
  • 34
    • 0022347638 scopus 로고
    • Microneutralization test for respiratory syncytial virus based on an enzyme immunoassay
    • Anderson LJ, Hierholzer JC, Bingham PG, Stone YO. 1985. Microneutralization test for respiratory syncytial virus based on an enzyme immunoassay. J. Clin. Microbiol. 22:1050-1052.
    • (1985) J. Clin. Microbiol. , vol.22 , pp. 1050-1052
    • Anderson, L.J.1    Hierholzer, J.C.2    Bingham, P.G.3    Stone, Y.O.4
  • 35
    • 33745158157 scopus 로고
    • A simple method of estimating fifty percent endpoints
    • Reed LJ, Muench H. 1938. A simple method of estimating fifty percent endpoints. Amer. J. Hyg. 27:493-497.
    • (1938) Amer. J. Hyg. , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 37
    • 0036347641 scopus 로고    scopus 로고
    • Substance P receptor expression on lymphocytes is associated with the immune response to respiratory syncytial virus infection
    • Tripp RA, Barskey A, Goss L, Anderson LJ. 2002. Substance P receptor expression on lymphocytes is associated with the immune response to respiratory syncytial virus infection. J. Neuroimmunol. 129:141-153.
    • (2002) J. Neuroimmunol. , vol.129 , pp. 141-153
    • Tripp, R.A.1    Barskey, A.2    Goss, L.3    Anderson, L.J.4
  • 39
    • 77950972810 scopus 로고    scopus 로고
    • Pharmacologic advances in the treatment and prevention of respiratory syncytial virus
    • Empey KM, Peebles RS, Kolls JK. 2010. Pharmacologic advances in the treatment and prevention of respiratory syncytial virus. Clin. Infect. Dis. 50:1258-1267.
    • (2010) Clin. Infect. Dis. , vol.50 , pp. 1258-1267
    • Empey, K.M.1    Peebles, R.S.2    Kolls, J.K.3
  • 41
    • 0033671154 scopus 로고    scopus 로고
    • Protection against respiratory syncytial virus (RSV) elicited in mice by plasmid DNA immunisation encoding a secreted RSV G protein-derived antigen
    • Andersson C, Liljestrom P, Stahl S, Power UF. 2000. Protection against respiratory syncytial virus (RSV) elicited in mice by plasmid DNA immunisation encoding a secreted RSV G protein-derived antigen. FEMS Immunol. Med. Microbiol. 29:247-253.
    • (2000) FEMS Immunol. Med. Microbiol. , vol.29 , pp. 247-253
    • Andersson, C.1    Liljestrom, P.2    Stahl, S.3    Power, U.F.4
  • 44
  • 45
    • 0032167369 scopus 로고    scopus 로고
    • Subcellular site of expression and route of vaccination influence pulmonary eosinophilia following respiratory syncytial virus challenge in BALB/c mice sensitized to the attachment G protein
    • Bembridge GP, Garcia-Beato R, Lopez JA, Melero JA, Taylor G. 1998. Subcellular site of expression and route of vaccination influence pulmonary eosinophilia following respiratory syncytial virus challenge in BALB/c mice sensitized to the attachment G protein. J. Immunol. 161: 2473-2480.
    • (1998) J. Immunol. , vol.161 , pp. 2473-2480
    • Bembridge, G.P.1    Garcia-Beato, R.2    Lopez, J.A.3    Melero, J.A.4    Taylor, G.5
  • 46
    • 0029817240 scopus 로고    scopus 로고
    • Generation of atypical pulmonary inflammatory responses in BALB/c mice after immunization with the native attachment (G) glycoprotein of respiratory syncytial virus
    • Hancock GE, Speelman DJ, Heers K, Bortell E, Smith J, Cosco C. 1996. Generation of atypical pulmonary inflammatory responses in BALB/c mice after immunization with the native attachment (G) glycoprotein of respiratory syncytial virus. J. Virol. 70:7783-7791.
    • (1996) J. Virol. , vol.70 , pp. 7783-7791
    • Hancock, G.E.1    Speelman, D.J.2    Heers, K.3    Bortell, E.4    Smith, J.5    Cosco, C.6
  • 47
    • 0032824135 scopus 로고    scopus 로고
    • Secreted respiratory syncytial virus G glycoprotein induces interleukin-5 (IL-5), IL-13, and eosinophilia by an IL-4-independent mechanism
    • Johnson TR, Graham BS. 1999. Secreted respiratory syncytial virus G glycoprotein induces interleukin-5 (IL-5), IL-13, and eosinophilia by an IL-4-independent mechanism. J. Virol. 73:8485-8495.
    • (1999) J. Virol. , vol.73 , pp. 8485-8495
    • Johnson, T.R.1    Graham, B.S.2
  • 49
    • 0032101551 scopus 로고    scopus 로고
    • Eliminating a region of respiratory syncytial virus attachment protein allows induction of protective immunity without vaccine- enhanced lung eosinophilia
    • Sparer TE, Matthews S, Hussell T, Rae AJ, Garcia-Barreno B, Melero JA, Openshaw PJ. 1998. Eliminating a region of respiratory syncytial virus attachment protein allows induction of protective immunity without vaccine- enhanced lung eosinophilia. J. Exp. Med. 187:1921-1926.
    • (1998) J. Exp. Med. , vol.187 , pp. 1921-1926
    • Sparer, T.E.1    Matthews, S.2    Hussell, T.3    Rae, A.J.4    Garcia-Barreno, B.5    Melero, J.A.6    Openshaw, P.J.7
  • 50
    • 0032538913 scopus 로고    scopus 로고
    • Atypical pulmonary eosinophilia is mediated by a specific amino acid sequence of the attachment (G) protein of respiratory syncytial virus
    • Tebbey PW, Hagen M, Hancock GE. 1998. Atypical pulmonary eosinophilia is mediated by a specific amino acid sequence of the attachment (G) protein of respiratory syncytial virus. J. Exp. Med. 188:1967-1972.
    • (1998) J. Exp. Med. , vol.188 , pp. 1967-1972
    • Tebbey, P.W.1    Hagen, M.2    Hancock, G.E.3
  • 51
    • 9644268234 scopus 로고    scopus 로고
    • Respiratory syncytial virus deficient in solubleGprotein induced an increased proinflammatory response in human lung epithelial cells
    • Arnold R, Konig B, Werchau H, Konig W. 2004. Respiratory syncytial virus deficient in solubleGprotein induced an increased proinflammatory response in human lung epithelial cells. Virology 330:384-397.
    • (2004) Virology , vol.330 , pp. 384-397
    • Arnold, R.1    Konig, B.2    Werchau, H.3    Konig, W.4
  • 52
    • 0035012174 scopus 로고    scopus 로고
    • Immunoregulatory role of secreted glycoprotein G from respiratory syncytial virus
    • Ray R, Hoft DF, Meyer K, Brown R, Lagging LM, Belshe RB. 2001. Immunoregulatory role of secreted glycoprotein G from respiratory syncytial virus. Virus Res. 75:147-154.
    • (2001) Virus Res. , vol.75 , pp. 147-154
    • Ray, R.1    Hoft, D.F.2    Meyer, K.3    Brown, R.4    Lagging, L.M.5    Belshe, R.B.6
  • 53
    • 84857082116 scopus 로고    scopus 로고
    • Respiratory syncytial virus glycoproteinGinteracts with DC-SIGN and L-SIGN to activate ERK1 and ERK2
    • Johnson TR, McLellan JS, Graham BS. 2012. Respiratory syncytial virus glycoproteinGinteracts with DC-SIGN and L-SIGN to activate ERK1 and ERK2. J. Virol. 86:1339-1347.
    • (2012) J. Virol. , vol.86 , pp. 1339-1347
    • Johnson, T.R.1    McLellan, J.S.2    Graham, B.S.3
  • 55
    • 33744925673 scopus 로고    scopus 로고
    • The cysteine-rich region and secreted form of the attachment G glycoprotein of respiratory syncytial virus enhance the cytotoxic T-lymphocyte response despite lacking major histocompatibility complex class I-restricted epitopes
    • Bukreyev A, Serra ME, Laham FR, Melendi GA, Kleeberger SR, Collins PL, Polack FP. 2006. The cysteine-rich region and secreted form of the attachment G glycoprotein of respiratory syncytial virus enhance the cytotoxic T-lymphocyte response despite lacking major histocompatibility complex class I-restricted epitopes. J. Virol. 80:5854-5861.
    • (2006) J. Virol. , vol.80 , pp. 5854-5861
    • Bukreyev, A.1    Serra, M.E.2    Laham, F.R.3    Melendi, G.A.4    Kleeberger, S.R.5    Collins, P.L.6    Polack, F.P.7
  • 56
    • 67049119148 scopus 로고    scopus 로고
    • Respiratory syncytial virus proteins modulate suppressors of cytokine sig- naling 1 and 3 and the type I interferon response to infection by a toll-like receptor pathway
    • Oshansky CM, Krunkosky TM, Barber J, Jones LP, Tripp RA. 2009. Respiratory syncytial virus proteins modulate suppressors of cytokine sig- naling 1 and 3 and the type I interferon response to infection by a toll-like receptor pathway. Viral Immunol. 22:147-161.
    • (2009) Viral Immunol. , vol.22 , pp. 147-161
    • Oshansky, C.M.1    Krunkosky, T.M.2    Barber, J.3    Jones, L.P.4    Tripp, R.A.5
  • 57
    • 57349108091 scopus 로고    scopus 로고
    • The secreted form of respiratory syncytial virus G glycoprotein helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy and through effects on Fc receptor-bearing leukocytes
    • Bukreyev A, Yang L, Fricke J, Cheng L, Ward JM, Murphy BR, Collins PL. 2008. The secreted form of respiratory syncytial virus G glycoprotein helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy and through effects on Fc receptor-bearing leukocytes. J. Virol. 82:12191-12204.
    • (2008) J. Virol. , vol.82 , pp. 12191-12204
    • Bukreyev, A.1    Yang, L.2    Fricke, J.3    Cheng, L.4    Ward, J.M.5    Murphy, B.R.6    Collins, P.L.7
  • 58
    • 0035927982 scopus 로고    scopus 로고
    • Respiratory syncytial virus and parainfluenza virus
    • Hall CB. 2001. Respiratory syncytial virus and parainfluenza virus. N. Engl. J. Med. 344:1917-1928.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1917-1928
    • Hall, C.B.1
  • 59
    • 0014733765 scopus 로고
    • Pathological changes in virus infections of the lower respiratory tract in children
    • Aherne W, Bird T, Court SD, Gardner PS, McQuillin J. 1970. Pathological changes in virus infections of the lower respiratory tract in children. J. Clin. Pathol. 23:7-18.
    • (1970) J. Clin. Pathol. , vol.23 , pp. 7-18
    • Aherne, W.1    Bird, T.2    Court, S.D.3    Gardner, P.S.4    McQuillin, J.5
  • 60
    • 33845709027 scopus 로고    scopus 로고
    • The histopathology of fatal untreated human respiratory syncytial virus infection
    • Johnson JE, Gonzales RA, Olson SJ, Wright PF, Graham BS. 2007. The histopathology of fatal untreated human respiratory syncytial virus infection. Mod. Pathol. 20:108-119.
    • (2007) Mod. Pathol. , vol.20 , pp. 108-119
    • Johnson, J.E.1    Gonzales, R.A.2    Olson, S.J.3    Wright, P.F.4    Graham, B.S.5
  • 62
    • 33644620356 scopus 로고    scopus 로고
    • Respiratory tract mucin genes and mucin glycoproteins in health and disease
    • Rose MC, Voynow JA. 2006. Respiratory tract mucin genes and mucin glycoproteins in health and disease. Physiol. Rev. 86:245-278.
    • (2006) Physiol. Rev. , vol.86 , pp. 245-278
    • Rose, M.C.1    Voynow, J.A.2
  • 64
    • 40049092917 scopus 로고    scopus 로고
    • Treatment strategies for allergy and asthma
    • Holgate ST, Polosa R. 2008. Treatment strategies for allergy and asthma. Nat. Rev. Immunol. 8:218-230.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 218-230
    • Holgate, S.T.1    Polosa, R.2
  • 67
    • 78649516120 scopus 로고    scopus 로고
    • The other T helper cells in asthma pathogenesis
    • doi:10.1155/2010/519298
    • Vock C, Hauber HP, Wegmann M. 2010. The other T helper cells in asthma pathogenesis. J. Allergy 2010:519298. doi:10.1155/2010/519298.
    • (2010) J. Allergy , vol.2010 , pp. 519298
    • Vock, C.1    Hauber, H.P.2    Wegmann, M.3
  • 71
    • 0034880117 scopus 로고    scopus 로고
    • Role of interleukin-12 and stat-4 in the regulation of airway inflammation and hyperreactivity in respiratory syncytial virus infection
    • Tekkanat KK, Maassab H, Berlin AA, Lincoln PM, EvanoffHL, Kaplan MH, Lukacs NW. 2001. Role of interleukin-12 and stat-4 in the regulation of airway inflammation and hyperreactivity in respiratory syncytial virus infection. Am. J. Pathol. 159:631-638.
    • (2001) Am. J. Pathol. , vol.159 , pp. 631-638
    • Tekkanat, K.K.1    Maassab, H.2    Berlin, A.A.3    Lincoln, P.M.4    Evanoff, H.L.5    Kaplan, M.H.6    Lukacs, N.W.7
  • 74
    • 34247567868 scopus 로고    scopus 로고
    • MyD88-mediated instructive signals in dendritic cells regulate pulmonary immune responses during respiratory virus infection
    • Rudd BD, Schaller MA, Smit JJ, Kunkel SL, Neupane R, Kelley L, Berlin AA, Lukacs NW. 2007. MyD88-mediated instructive signals in dendritic cells regulate pulmonary immune responses during respiratory virus infection. J. Immunol. 178:5820-5827.
    • (2007) J. Immunol. , vol.178 , pp. 5820-5827
    • Rudd, B.D.1    Schaller, M.A.2    Smit, J.J.3    Kunkel, S.L.4    Neupane, R.5    Kelley, L.6    Berlin, A.A.7    Lukacs, N.W.8
  • 75
    • 79251535010 scopus 로고    scopus 로고
    • Neurokinin-1 receptor: functional significance in the immune system in reference to selected infections and inflammation
    • Douglas SD, Leeman SE. 2011. Neurokinin-1 receptor: functional significance in the immune system in reference to selected infections and inflammation. Ann. N. Y. Acad. Sci. 1217:83-95.
    • (2011) Ann. N. Y. Acad. Sci. , vol.1217 , pp. 83-95
    • Douglas, S.D.1    Leeman, S.E.2
  • 77
    • 33646146936 scopus 로고    scopus 로고
    • Protection of mice against human respiratory syncytial virus by wild-type and aglycosyl mouse-human chimaeric IgG antibodies to subgroup-conserved epitopes on the G glycoprotein
    • Mekseepralard C, Toms GL, Routledge EG. 2006. Protection of mice against human respiratory syncytial virus by wild-type and aglycosyl mouse-human chimaeric IgG antibodies to subgroup-conserved epitopes on the G glycoprotein. J. Gen. Virol. 87:1267-1273.
    • (2006) J. Gen. Virol. , vol.87 , pp. 1267-1273
    • Mekseepralard, C.1    Toms, G.L.2    Routledge, E.G.3
  • 78
    • 37449013995 scopus 로고    scopus 로고
    • The RSV F and G glycoproteins interact to form a complex on the surface of infected cells
    • Low KW, Tan T, Ng K, Tan BH, Sugrue RJ. 2008. The RSV F and G glycoproteins interact to form a complex on the surface of infected cells. Biochem. Biophys. Res. Commun. 366:308-313.
    • (2008) Biochem. Biophys. Res. Commun. , vol.366 , pp. 308-313
    • Low, K.W.1    Tan, T.2    Ng, K.3    Tan, B.H.4    Sugrue, R.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.