Toll-like receptor 4 agonists adsorbed to aluminium hydroxide adjuvant attenuate ovalbumin-specific allergic airway disease: Role of MyD88 adaptor molecule and interleukin-12/interferon-γ axis

Clinical and Experimental Allergy

Volumn 38, Issue 10, 2008, Pages 1668-1679

  Bortolatto, J ^a   Borducchi, E ^a   Rodriguez, D ^a   Keller, A C ^a   Faquim Mauro, E ^a,b   Bortoluci, K R ^a   Mucida, D ^a   Gomes, E ^a   Christ, A ^a   Schnyder Candrian, S ^c   Schnyder, B ^c   Ryffel, B ^c   Russo, M ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

^c CNRS   (France)

Author keywords

Airway hyper reactivity; Allergic airway inflammation; LPS; MyD88; TLR4 signaling

Indexed keywords

ADJUVANT; ALUMINUM HYDROXIDE; ALUMINUM POTASSIUM SULFATE; CYTOKINE RECEPTOR AGONIST; ER 803022; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; OVALBUMIN; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 4 AGONIST; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; LOEFFLER PNEUMONIA; MOUSE; MUCUS SECRETION; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; SENSITIZATION; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ADJUVANTS, IMMUNOLOGIC; ALLERGENS; ALUMINUM HYDROXIDE; ANIMALS; ANTIBODIES; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; INTERFERON-GAMMA; INTERLEUKIN-12; LIPOPOLYSACCHARIDES; LUNG; MICE; MICE, INBRED BALB C; MYELOID DIFFERENTIATION FACTOR 88; OVALBUMIN; PHOSPHOLIPIDS; TOLL-LIKE RECEPTOR 4;

EID: 53749099495     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2008.03036.x     Document Type: Article

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