Subcellular site of expression and route of vaccination influence pulmonary eosinophilia following respiratory syncytial virus challenge in BALB/c mice sensitized to the attachment G protein

Journal of Immunology

Volumn 161, Issue 5, 1998, Pages 2473-2480

  Bembridge, Gary P ^a   Garcia Beato, Regina ^b   López, Juan A ^b   Melero, Jose A ^b   Taylor, Geraldine ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; VIRUS GLYCOPROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; EOSINOPHILIA; FEMALE; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY TRACT INFECTION; SENSITIZATION; T LYMPHOCYTE SUBPOPULATION; VACCINATION; VACCINIA VIRUS; VIRUS INFECTION; VIRUS RECOMBINANT;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIBODIES, VIRAL; ANTIBODY SPECIFICITY; ANTIGENS, VIRAL; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; HN PROTEIN; INJECTIONS, INTRAPERITONEAL; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; PULMONARY EOSINOPHILIA; RECOMBINANT PROTEINS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; SOLUBILITY; SPLEEN; SUBCELLULAR FRACTIONS; TH2 CELLS; VACCINIA VIRUS; VIRAL ENVELOPE PROTEINS; VIRAL PROTEINS; VIRAL VACCINES;

EID: 0032167369     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. + T cell responses: the alternative approaches. Annu. Rev. Immunol. 15:297.
2. Fulginiti, V. A., J. J. Eller, O. F. Sieber, J. W. Joyner, M. Minamitani, and G. Meiklejohn. 1969. Respiratory virus immunization. I. A field trial of two inactivated respiratory virus vaccines: an aqueous trivalent parainfluenza virus vaccine and an alum-precipitated respiratory syncytial virus vaccine. Am. J. Epidemiol. 89:436.
3. Kim, H. W., J. G. Canchola, C. D. Brandt, G. Pyles, R. M. Chanock, K. Jensen, and R. H. Parrott. 1969. Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine. Am. J. Epidemiol. 89:422.
4. Stott, E. J., G. Taylor, L. A. Ball, K. Anderson, K. K.-Y. Young, A. M. Q. King, and G. W. Wertz. 1987. Immune and histopathological responses in animals vaccinated with recombinant vaccinia viruses that express individual genes of human respiratory syncytial virus. J. Virol. 61:3855.
5. Openshaw, P. J., S. L. Clarke, and F. M. Record. 1992. Pulmonary eosinophilic response to respiratory syncytial virus infection in mice sensitized to the major surface glycoprotein G. Int. Immunol. 4:493.
6. Srikiatkhachorn, A., and T. J. Braciale. 1997. Virus-specific memory and effector T lymphocytes exhibit different cytokine responses to antigens during experimental murine respiratory syncytial virus infection. J. Virol. 71:678.
7. Alwan, W. H., and P. J. Openshaw. 1993. Distinct patterns of T- and B-cell immunity to respiratory syncytial virus induced by individual viral proteins. Vaccine 11:431.
8. Walsh, E. E., and J. Hruska. 1983. Monoclonal antibodies to respiratory syncytial virus protein: identification of the fusion protein. J. Virol. 47:171.
9. Lopez, J. A., R. Bustos, A. Portela, B. Garcia-Barreno, and J. A. Melero. 1996. A point mutation in the F1 subunit of human respiratory syncytial virus blocks its cell surface transport at an early stage of the exocytic pathway. J. Gen. Virol. 77:649.
10. Roberts, S. R., D. Lichtenstein, L. A. Ball, and G. W. Wertz. 1994. The membrane-associated and secreted forms of the respiratory syncytial virus attachment glycoprotein G are synthesized from alternative initiation codons. J. Virol. 68: 4538.
11. Wertz, G. W., P. L. Collins, Y. Huang, C. Gruber, S. Levine, and L. A. Ball. 1985. Nucleotide sequence of the G protein gene of human respiratory syncytial virus reveals an unusual type of viral membrane protein. Proc. Natl. Acad. Sci. USA 82:4075.
12. Satake, M., J. E. Coligan, N. Elango, E. Norrby, and S. Venkatesan. 1985. Respiratory syncytial virus envelope glycoprotein (G) has a novel structure. Nucleic Acids Res. 13:7795.
13. Lambert, D. M. 1988. Role of oligosaccharides in the structure and function of respiratory syncytial virus glycoproteins. Virology 164:458.
14. Gruber, C., and S. Levine. 1985. Respiratory syncytial virus polypeptides. IV. The oligosaccharides of the glycoproteins. J. Gen. Virol. 66:417.
15. Wertz, G. W., M. Krieger, and L. A. Ball. 1989. Structure and cell surface maturation of the attachment glycoprotein of human respiratory syncytial virus in a cell line deficient in O glycosylation. J. Virol. 63:4767.
16. Garcia-Barreno, B., J. L. Jorcano, T. Aukenhauer, C. Lopez-Galindez, and J. A. Melero. 1988. Participation of cytoskeletol intermediate filaments in the infectious cycle of human respiratory syncytial virus (RSV). Virus Res. 9:307.
17. Chakrabarti, S., K. Brechung, and B. Moss. 1985. Vaccinia virus expression vector: coexpression of β-galactosidase provides visual screening of recombinant virus plaques. Mol. Cell Biol. 5:3403.
18. Blasco, R., and B. Moss. 1995. Selection of recombinant vaccinia viruses on the basis of plaque formation. Gene 158:157.
19. Cristina, J., J. A. Lopez, C. Albo, B. Garciabarreno, J. Garcia, J. A. Melero, and A. Portela. 1990. Analysis of genetic variability in human respiratory syncytial virus by the RNase-A mismatch cleavage method: subtype divergence and heterogeneity. Virology 174:126.
20. Higuchi, R., B. Krummel, and R. K. Saiki. 1988. A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res. 16:7351.
21. Arbiza, J., G. Taylor, J. A. Lopez, J. Furze, S. Wyld, P. Whyte, E. J. Stott, G. Wertz, W. Sullender, M. Trudel, and J. A. Melero. 1992. Characterization of 2 antigenic sites recognized by neutralizing monoclonal antibodies directed against the fusion glycoprotejn of respiratory syncytial virus. J. Gen. Virol. 73: 2225.
22. Taylor, G., E. J. Stott, M. Hughes, and A. P. Collins. 1984. Respiratory syncytial virus-infection in mice. Infect. Immun. 43:649.
23. Openshaw, P. J. M. 1989. Flow cytometric analysis of pulmonary lymphocytes from mice infected with respiratory syncytial virus. Clin. Exp. Immunol. 75:324.
24. Taylor, G., E. J. Stott, J. Furze, J. Ford, and P. Sopp. 1992. Protective epitopes on the fusion protein of respiratory syncytial virus recognized by murine and bovine monoclonal antibodies. J. Gen. Virol. 73:2217.
25. Rueda, P., B. Garcia-Barreno, and J. A. Melero. 1994. Loss of conserved cysteine residues in the attachment (G) glycoprotein of two human respiratory syncytial virus escape mutants that contain multiple A-G substitutions (hypermutations). Virology 198:653.
26. Gaddum, R. M., R. S. Cook, S. G. Wyld, J. A. Lopez, R. Bustos, J. A. Melero, and G. Taylor. 1996. Mutant forms of the F protein of human respiratory syncytial (RS) virus induce a cytotoxic T lymphocyte response but not a neutralizing antibody response and only transient resistance to RS virus infection. J. Gen. Virol. 77:1239.
27. Parish, C. R., and F. Y. Liew. 1972. Immune response to chemically modified flagellin. III. Enhanced cell-mediated immunity during high and low zone antibody tolerance to flagellin. J. Exp. Med. 135:298.
28. Bretscher, P. A., G. Wei, J. N. Menon, and H. Bielefeldt-Ohmann. 1992. Establishment of stable cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major. Science 257:539.
29. Bancroft, A. J., K. J. Else, and R. K. Grencis. 1994. Low-level infection with Trichuris muris significantly affects the polarization of the CD4 response. Eur. J. Immunol. 24:3113.
30. Burstein, H. J., C. M. Shea, and A. K. Abbas. 1992. Aqueous antigens induce in vivo tolerance selectively in IL-2- and IFN-γ-producing (Th1) cells. J. Immunol. 148:3687.
31. Hancock, G. E., D. J. Speelman, K. Heers, E. Bortell, J. Smith, and C. Cosco. 1996. Generation of atypical pulmonary inflammatory responses in BALB/c mice after immunization with the native attachment (G) glycoprotein of respiratory syncytial virus. J. Virol. 70:7783.
32. + T cells, while that induced by Vac-F or Vac-G recombinants is mediated by antibodies. J. Virol. 66:1277.
33. Alwan, W. H., W. J. Kozlowski, and P. J. M. Openshaw. 1994. Distinct types of lung disease caused by functional subsets of antiviral T cells. J. Exp. Med. 179: 81.
34. + T cells control Th2 driven pathology during pulmonary respiratory syncytial virus infection. Eur. J. Immunol. 27:3341.
35. + T lymphocytes downregulate T helper cell type 2 cytokines secretion and pulmonary eo-sinophilia during experimental murine respiratory syncytial virus infection. J. Exp. Med. 186:421.
36. Pemberton, R. M., M. J. Cannon, P. J. M. Openshaw, L. A. Ball, G. W. Wertz, and B. A. Askonas. 1987. Cytotoxic T-cell specificity for respiratory syncytial virus proteins: fusion protein is an important target antigen. J. Gen. Virol. 68: 2177.
37. Renz, H., G. Lack, J. Saloga, R. Schwinzer, K. Bradley, J. Loader, A. Lupfer, G. L. Larsen, and E. W. Gelfand. 1994. Inhibition of IgE production and normalization of airway responsiveness by sensitized CD8 T cells in a mouse model of allergen induced sensitization. J. Immunol. 152:351.
38. + T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production. J. Exp. Med. 178:889.
39. + cells can switch to interleukin 5 production and induce airway eosinophilia. J. Exp. Med. 181:1229.