Eukaryotic initiation factor 2α phosphorylation mediates fetal hemoglobin induction through a post-transcriptional mechanism

Blood

Volumn 122, Issue 4, 2013, Pages 477-485

  Hahn, Cynthia K ^a   Lowrey, Christopher H ^a,b,c  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^c NORRIS COTTON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN F; INITIATION FACTOR 2ALPHA; PROTEIN CREP; PROTEIN GADD34; REGULATOR PROTEIN; SALUBRINAL; UNCLASSIFIED DRUG; CINNAMIC ACID DERIVATIVE; DRUG DERIVATIVE; ENZYME INHIBITOR; INITIATION FACTOR 2; THIOUREA;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ERYTHROID PRECURSOR CELL; GENE EXPRESSION; GLOBIN GENE; HUMAN; HUMAN CELL; PRIMARY CELL; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSLATION INITIATION; BIOLOGICAL MODEL; CELL STRAIN K 562; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; HEMOGLOBINOPATHY; METABOLISM; METHODOLOGY; MOLECULARLY TARGETED THERAPY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN SYNTHESIS;

CINNAMATES; ENZYME INHIBITORS; ERYTHROID PRECURSOR CELLS; EUKARYOTIC INITIATION FACTOR-2; FETAL HEMOGLOBIN; HEMOGLOBINOPATHIES; HUMANS; K562 CELLS; MODELS, BIOLOGICAL; MOLECULAR TARGETED THERAPY; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; SIGNAL TRANSDUCTION; THIOUREA; TRANSCRIPTION, GENETIC;

EID: 84886904254     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-03-491043     Document Type: Article

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