Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin

Blood

Volumn 111, Issue 1, 2008, Pages 411-420

  Mabaera, Rodwell ^a   Greene, Michael R ^a   Richardson, Christine A ^a   Conine, Sarah J ^a   Kozul, Courtney D ^a   Lowrey, Christopher H ^a,b,c  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b NORRIS COTTON CANCER CENTER   (United States)

^c DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; DNA; DNA METHYLTRANSFERASE 1; GAMMA GLOBIN; HEMOGLOBIN F; MESSENGER RNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

ARTICLE; BETA THALASSEMIA; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA HYPOMETHYLATION; DNA METHYLATION; ERYTHROID CELL; GLOBIN GENE; HEMOGLOBIN SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN INDUCTION; SICKLE CELL ANEMIA; TRANSCRIPTION REGULATION;

EID: 38049156451     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2007-06-093948     Document Type: Article

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