Steap4 plays a critical role in osteoclastogenesis in vitro by regulating cellular iron/reactive oxygen species (ROS) levels and cAMP response element-binding protein (CREB) activation

Journal of Biological Chemistry

Volumn 288, Issue 42, 2013, Pages 30064-30074

  Zhou, Jian ^a   Ye, Shiqiao ^a   Fujiwara, Toshifumi ^a   Manolagas, Stavros C ^a   Zhao, Haibo ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR IRONS; ELEMENT-BINDING PROTEINS; IRON UPTAKE; MOLECULAR MECHANISM; OSTEOCLAST DIFFERENTIATION; OSTEOCLAST FORMATION; OSTEOCLASTOGENESIS; OXYGEN SPECIES;

METABOLISM; PHYSIOLOGY;

IRON;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FERRIC ION; IRON; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; SIX TRANSMEMBRANE EPITHELIAL ANTIGEN OF PROSTATE 4; TRANSFERRIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ATP5B GENE; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; COX I GENE; COX III GENE; COX VIIA GENE; ENDOSOME; GENE EXPRESSION; IN VITRO STUDY; IRON METABOLISM; IRON TRANSPORT; MACROPHAGE; MITOCHONDRIAL GENE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

BONE; IRON METABOLISM; MITOCHONDRIA; OSTEOCLAST; OXIDATIVE STRESS;

ANIMALS; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENDOSOMES; FMN REDUCTASE; GENE KNOCKDOWN TECHNIQUES; IRON; MEMBRANE PROTEINS; MICE; OSTEOCLASTS; REACTIVE OXYGEN SPECIES;

EID: 84886880324     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.478750     Document Type: Article

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