Downregulation of Small GTPase Rab7 Impairs Osteoclast Polarization and Bone Resorption

Journal of Biological Chemistry

Volumn 276, Issue 42, 2001, Pages 39295-39302

  Zhao, Haibo ^a   Laitala Leinonen, Tiina ^b   Parikka, Vilhelmiina ^b   Väänänen, H Kalervo ^b  

^a BARNES JEWISH HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; BONE; POLARIZATION; PROTONS;

OSTEOCLASTS;

ENZYMES;

ANTISENSE OLIGODEOXYNUCLEOTIDE; GUANOSINE TRIPHOSPHATASE; PROTEINASE; PROTON; RAB PROTEIN; RAB7 PROTEIN; UNCLASSIFIED DRUG; ACTIN; ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA; OLIGONUCLEOTIDE; RAB11 PROTEIN; TRANSFERRIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE GROWTH; BONE MATRIX; BONE REMODELING; CELL FUNCTION; CELL MEMBRANE; CELL TRANSPORT; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; ENDOSOME; ENZYME RELEASE; MINERALIZATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOCLAST; OSTEOLYSIS; POLARIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT; ANIMAL; CATTLE; CELL CULTURE; CONFOCAL MICROSCOPY; DOSE RESPONSE; ELECTRON MICROSCOPY; EXTRACELLULAR MATRIX; FLUORESCENCE MICROSCOPY; METABOLISM; MOLECULAR GENETICS; NEWBORN; PROTEIN BINDING; TIME; WESTERN BLOTTING;

ANIMALIA;

ACTINS; ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; BONE RESORPTION; CATTLE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; EXTRACELLULAR MATRIX; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; OLIGONUCLEOTIDES, ANTISENSE; OSTEOCLASTS; PROTEIN BINDING; RAB GTP-BINDING PROTEINS; RATS; RNA, MESSENGER; TIME FACTORS; TRANSFERRIN;

EID: 0035914465     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010999200     Document Type: Article

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