Expression of six transmembrane protein of prostate 2 in human adipose tissue associates with adiposity and insulin resistance

Journal of Clinical Endocrinology and Metabolism

Volumn 93, Issue 6, 2008, Pages 2249-2254

  Arner, Peter ^a,c   Stenson, Britta M ^a   Dungner, Elisabeth ^a   Näslund, Erik ^b   Hoffstedt, Johan ^a   Ryden, Mikael ^a   Dahlman, Ingrid ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b DANDERYD HOSPITAL   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; INSULIN; PROSTATE PROTEIN; PROTEIN STAMP2;

ABDOMINAL SUBCUTANEOUS FAT; ADULT; ARTICLE; BODY FAT; BODY MASS; CELL SIZE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; GENE EXPRESSION; HOMEOSTASIS; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; LIPOGENESIS; LIPOLYSIS; MAJOR CLINICAL STUDY; MALE; OBESITY; OUTCOME ASSESSMENT; PHENOTYPE; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; STROMA; WEIGHT REDUCTION; WHITE ADIPOSE TISSUE;

MUS;

EID: 45149093957     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-0206     Document Type: Article

References (12)

1. Gustafson B, Hammarstedt A, Andersson CX, Smith U 2007 Inflamed adipose tissue: a culprit underlying the metabolic syndrome and atherosclerosis. Arterioscler Thromb Vasc Biol 27:2276-2283
2. Wellen KE, Fucho R, Gregor MF, Furuhashi M, Morgan C, Lindstad T, Vaillancourt E, Gorgun CZ, Saatcioglu F, Hotamisligil GS 2007 Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis. Cell 129:537-548
3. Moldes M, Lasnier F, Gauthereau X, Klein C, Pairault J, Feve B, Chambaut-Guerin AM 2001 Tumor necrosis factor-α-induced adipose-related protein (TIARP), a cell-surface protein that is highly induced by tumor necrosis factor-α and adipose conversion. J Biol Chem 276:33938-33946
4. Lofgren P, Hoffstedt J, Naslund E, Wiren M, Arner P 2005 Prospective and controlled studies of the actions of insulin and catecholamine in fat cells of obese women following weight reduction. Diabetologia 48:2334-2342
5. Bonora E, Targher G, Alberiche M, Bonadonna RC, Saggiani F, Zenere MB, Monauni T, Muggeo M 2000 Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care 23:57-63
6. Hoffstedt J, Arvidsson E, Sjolin E, Wahlen K, Arner P 2004 Adipose tissue adiponectin production and adiponectin serum concentration in human obesity and insulin resistance. J Clin Endocrinol Metab 89:1391-1396
7. van Harmelen V, Dicker A, Ryden M, Hauner H, Lonnqvist F, Naslund E, Arner P 2002 Increased lipolysis and decreased leptin production by human omental as compared with subcutaneous preadipocytes. Diabetes 51:2029-2036
8. Ryden M, Dicker A, van Harmelen V, Hauner H, Brunnberg M, Perbeck L, Lonnqvist F, Arner P 2002 Mapping of early signaling events in tumor necrosis factor-α-mediated lipolysis in human fat cells. J Biol Chem 277:1085-1091
9. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante Jr AW 2003 Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112:1796-1808
10. Khazen W, M'bika JP, Tomkiewicz C, Benelli C, Chany C, Achour A, Forest C 2005 Expression of macrophage-selective markers in human and rodent adipocytes. FEBS Lett 579:5631-5634
11. Dahlman I, Forsgren M, Sjogren A, Nordstrom EA, Kaaman M, Naslund E, Attersand A, Arner P 2006 Downregulation of electron transport chain genes in visceral adipose tissue in type 2 diabetes independent of obesity and possibly involving tumor necrosis factor-α. Diabetes 55:1792-1799
12. Kolak M, Westerbacka J, Velagapudi VR, Wågsäter D, Yetukuri L, Makkonen J, Rissanen A, Häkkinen AM, Lindell M, Bergholm R, Hamsten A, Eriksson P, Fisher RM, Oresic M, Yki-Järvinen H 2007 Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity. Diabetes 56: 1960-1968