메뉴 건너뛰기




Volumn 23, Issue 10, 2012, Pages 2403-2408

Iron homeostasis in osteoporosis and its clinical implications

Author keywords

Hepcidin; Iron overload; Osteoporosis

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; CALCIUM CHANNEL BLOCKING AGENT; CHELATING AGENT; DEFERIPRONE; DEFEROXAMINE; EDETIC ACID; FERROPORTIN; HEPCIDIN; HYDROXYAPATITE; IRON; NIMODIPINE;

EID: 84867334961     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-012-1982-1     Document Type: Review
Times cited : (86)

References (85)
  • 1
    • 0442288499 scopus 로고
    • Osteoporosis in hemochromatosis
    • Delbarre F (1960) Osteoporosis in hemochromatosis. Sem Hop 36:3279-3294
    • (1960) Sem Hop , vol.36 , pp. 3279-3294
    • Delbarre, F.1
  • 2
    • 84867336347 scopus 로고
    • Osteoarticular manifestations of hemochromatosis
    • Delbarre F (1964) Osteoarticular manifestations of hemochromatosis. Presse Med 72:2973-2978
    • (1964) Presse Med , vol.72 , pp. 2973-2978
    • Delbarre, F.1
  • 5
    • 0024742249 scopus 로고
    • Roentgenologic studies of changes of the osteoarticular system in patients with hereditary hemochromatosis
    • Kagan IE, Settarova DA, Tokarev Iu. N, Burdina LM (1989) Roentgenologic studies of changes of the osteoarticular system in patients with hereditary hemochromatosis. Gematol Transfuziol 34(10):19-24
    • (1989) Gematol Transfuziol , vol.34 , Issue.10 , pp. 19-24
    • Kagan, I.E.1    Settarova, D.A.2    Iu, T.N.3    Burdina, L.M.4
  • 6
    • 0015785826 scopus 로고
    • Arthropathy secondary to transfusion hemochromatosis
    • Sella EJ, Goodman AH (1973) Arthropathy secondary to transfusion hemochromatosis. J Bone Joint Surg Am 55(5):1077-1081
    • (1973) J Bone Joint Surg Am , vol.55 , Issue.5 , pp. 1077-1081
    • Sella, E.J.1    Goodman, A.H.2
  • 7
    • 0014461608 scopus 로고
    • Bone and joint changes in haemochromatosis
    • Wardle EN, Patton JT (1969) Bone and joint changes in haemochromatosis. Ann Rheum Dis 28(1):15-23
    • (1969) Ann Rheum Dis , vol.28 , Issue.1 , pp. 15-23
    • Wardle, E.N.1    Patton, J.T.2
  • 8
    • 0014110339 scopus 로고
    • Apropos of osteoarthropathies in idiopathic hemochromatoses
    • Nicolino J, Lucciani JM (1967) Apropos of osteoarthropathies in idiopathic hemochromatoses. Diabete 15(3):196-200
    • (1967) Diabete , vol.15 , Issue.3 , pp. 196-200
    • Nicolino, J.1    Lucciani, J.M.2
  • 9
    • 0014178874 scopus 로고
    • Arthropathies and chondrocalcinosis during hemochromatosis
    • Du Lac Y, Deloux G, Deuil R (1967) Arthropathies and chondrocalcinosis during hemochromatosis. Rev Rhum Mal Osteoartic 34(12):758-769
    • (1967) Rev Rhum Mal Osteoartic , vol.34 , Issue.12 , pp. 758-769
    • Lac, Y.D.1    Deloux, G.2    Deuil, R.3
  • 11
    • 0014813267 scopus 로고
    • Some aspects of calcium metabolism in normal and osteoporotic Bantu subjects with special reference to the effects of iron overload and ascorbic acid depletion
    • Lynch SR, Seftel HC, Wapnick AA, Charlton RW, Bothwell TH (1970) Some aspects of calcium metabolism in normal and osteoporotic Bantu subjects with special reference to the effects of iron overload and ascorbic acid depletion. S Afr J Med Sci 35(2):45-56
    • (1970) S Afr J Med Sci , vol.35 , Issue.2 , pp. 45-56
    • Lynch, S.R.1    Seftel, H.C.2    Wapnick, A.A.3    Charlton, R.W.4    Bothwell, T.H.5
  • 15
    • 0024554054 scopus 로고
    • Osteoporosis in hemochromatosis: Iron excess, gonadal deficiency, or other factors?
    • Diamond T, Stiel D, Posen S (1989) Osteoporosis in hemochromatosis: iron excess, gonadal deficiency, or other factors? Ann Intern Med 110(6):430-436
    • (1989) Ann Intern Med , vol.110 , Issue.6 , pp. 430-436
    • Diamond, T.1    Stiel, D.2    Posen, S.3
  • 17
    • 0025871593 scopus 로고
    • Rheumatic manifestations of haemochromatosis
    • Axford JS (1991) Rheumatic manifestations of haemochromatosis. Baillieres Clin Rheumatol 5(2):351-365
    • (1991) Baillieres Clin Rheumatol , vol.5 , Issue.2 , pp. 351-365
    • Axford, J.S.1
  • 19
    • 0033090426 scopus 로고    scopus 로고
    • Osteoarticular hemochromatosis
    • Zeevaert B, Crielaard JM (1999) Osteoarticular hemochromatosis. Rev Med Liege 54(3):169-174
    • (1999) Rev Med Liege , vol.54 , Issue.3 , pp. 169-174
    • Zeevaert, B.1    Crielaard, J.M.2
  • 23
    • 33846119350 scopus 로고    scopus 로고
    • Iron overload and arthropathy
    • Chales G, Guggenbuhl P, Pawlotsky Y (2006) Iron overload and arthropathy. Rev Prat 56(19):2135-2140
    • (2006) Rev Prat , vol.56 , Issue.19 , pp. 2135-2140
    • Chales, G.1    Guggenbuhl, P.2    Pawlotsky, Y.3
  • 24
    • 62149108646 scopus 로고    scopus 로고
    • Association between iron overload and osteoporosis in patients with hereditary hemochromatosis
    • Valenti L, Varenna M, Fracanzani AL, Rossi V, Fargion S, Sinigaglia L (2009) Association between iron overload and osteoporosis in patients with hereditary hemochromatosis. Osteoporos Int 20(4):549-555
    • (2009) Osteoporos Int , vol.20 , Issue.4 , pp. 549-555
    • Valenti, L.1    Varenna, M.2    Fracanzani, A.L.3    Rossi, V.4    Fargion, S.5    Sinigaglia, L.6
  • 25
    • 77957878136 scopus 로고    scopus 로고
    • Musculoskeletal complications of hereditary hemochromatosis: A case-control study
    • Richette P, Ottaviani S, Vicaut E, Bardin T (2010) Musculoskeletal complications of hereditary hemochromatosis: a case-control study. J Rheumatol 37(10):2145-2150
    • (2010) J Rheumatol , vol.37 , Issue.10 , pp. 2145-2150
    • Richette, P.1    Ottaviani, S.2    Vicaut, E.3    Bardin, T.4
  • 28
    • 0016278793 scopus 로고
    • African haemosiderosis associated with osteoporosis and vertebral collapse
    • Lorincz G, Traub NE, Chuke PO, Hussain SF (1974) African haemosiderosis associated with osteoporosis and vertebral collapse. East Afr Med J 51(6):488-495
    • (1974) East Afr Med J , vol.51 , Issue.6 , pp. 488-495
    • Lorincz, G.1    Traub, N.E.2    Chuke, P.O.3    Hussain, S.F.4
  • 30
    • 18444361802 scopus 로고    scopus 로고
    • Ascorbic acid deficiency, iron overload and alcohol abuse underlie the severe osteoporosis in black African patients with hip fractures-A bone histomorphometric study
    • Schnitzler CM, Schnaid E, MacPhail AP, Mesquita JM, Robson HJ (2005) Ascorbic acid deficiency, iron overload and alcohol abuse underlie the severe osteoporosis in black African patients with hip fractures-a bone histomorphometric study. Calcif Tissue Int 76(2):79-89
    • (2005) Calcif Tissue Int , vol.76 , Issue.2 , pp. 79-89
    • Schnitzler, C.M.1    Schnaid, E.2    MacPhail, A.P.3    Mesquita, J.M.4    Robson, H.J.5
  • 31
    • 0025038048 scopus 로고
    • Bone disease in children with homozygous beta-thalassemia
    • Rioja L, Girot R, Garabedian M, Cournot-Witmer G (1990) Bone disease in children with homozygous beta-thalassemia. Bone Miner 8(1):69-86
    • (1990) Bone Miner , vol.8 , Issue.1 , pp. 69-86
    • Rioja, L.1    Girot, R.2    Garabedian, M.3    Cournot-Witmer, G.4
  • 33
    • 5644257032 scopus 로고    scopus 로고
    • New insights into the pathophysiology and management of osteoporosis in patients with beta thalassaemia
    • Voskaridou E, Terpos E (2004) New insights into the pathophysiology and management of osteoporosis in patients with beta thalassaemia. Br J Haematol 127(2):127-139
    • (2004) Br J Haematol , vol.127 , Issue.2 , pp. 127-139
    • Voskaridou, E.1    Terpos, E.2
  • 34
    • 33748498701 scopus 로고    scopus 로고
    • Unbalanced bone turnover in children with beta-thalassemia
    • Salama OS, Al-Tonbary YA, Shahin RA, Eldeen OA (2006) Unbalanced bone turnover in children with beta-thalassemia. Hematology 11(3):197-202
    • (2006) Hematology , vol.11 , Issue.3 , pp. 197-202
    • Salama, O.S.1    Al-Tonbary, Y.A.2    Shahin, R.A.3    Eldeen, O.A.4
  • 37
    • 79951725817 scopus 로고    scopus 로고
    • Does high serum iron level induce low bone mass in sickle cell anemia?
    • Sadat-Ali M, Sultan O, Al-Turki H, Alelq A (2011) Does high serum iron level induce low bone mass in sickle cell anemia? Biometals 24(1):19-22
    • (2011) Biometals , vol.24 , Issue.1 , pp. 19-22
    • Sadat-Ali, M.1    Sultan, O.2    Al-Turki, H.3    Alelq, A.4
  • 39
    • 78049462301 scopus 로고    scopus 로고
    • Hepatic osteodystrophy in patients with liver cirrhosis
    • Topcheeva ON (2010) Hepatic osteodystrophy in patients with liver cirrhosis. Eksp Klin Gastroenterol 6:89-94
    • (2010) Eksp Klin Gastroenterol , vol.6 , pp. 89-94
    • Topcheeva, O.N.1
  • 41
    • 77950894593 scopus 로고    scopus 로고
    • Hepatic osteodystrophy and liver cirrhosis
    • Goral V, Simsek M, Mete N (2010) Hepatic osteodystrophy and liver cirrhosis. World J Gastroenterol 16(13):1639-1643
    • (2010) World J Gastroenterol , vol.16 , Issue.13 , pp. 1639-1643
    • Goral, V.1    Simsek, M.2    Mete, N.3
  • 42
    • 33646843750 scopus 로고    scopus 로고
    • Hyperbilirubinemia is not a major contributing factor to altered bone mineral density in patients with chronic liver disease
    • Smith DL, Shire NJ, Watts NB, Schmitter T, Szabo G, Zucker SD (2006) Hyperbilirubinemia is not a major contributing factor to altered bone mineral density in patients with chronic liver disease. J Clin Densitom 9(1):105-113
    • (2006) J Clin Densitom , vol.9 , Issue.1 , pp. 105-113
    • Smith, D.L.1    Shire, N.J.2    Watts, N.B.3    Schmitter, T.4    Szabo, G.5    Zucker, S.D.6
  • 43
    • 0025021543 scopus 로고
    • Osteoporosis and skeletal fractures in chronic liver disease
    • Diamond T, Stiel D, Lunzer M, Wilkinson M, Roche J, Posen S (1990) Osteoporosis and skeletal fractures in chronic liver disease. Gut 31(1):82-87
    • (1990) Gut , vol.31 , Issue.1 , pp. 82-87
    • Diamond, T.1    Stiel, D.2    Lunzer, M.3    Wilkinson, M.4    Roche, J.5    Posen, S.6
  • 44
    • 0017880720 scopus 로고
    • Clinical, biochemical, and histological studies of osteomalacia, osteoporosis, and parathyroid function in chronic liver disease
    • Long RG, Meinhard E, Skinner RK, Varghese Z, Wills MR, Sherlock S (1978) Clinical, biochemical, and histological studies of osteomalacia, osteoporosis, and parathyroid function in chronic liver disease. Gut 19(2):85-90
    • (1978) Gut , vol.19 , Issue.2 , pp. 85-90
    • Long, R.G.1    Meinhard, E.2    Skinner, R.K.3    Varghese, Z.4    Wills, M.R.5    Sherlock, S.6
  • 45
    • 0035896642 scopus 로고    scopus 로고
    • Hepcidin, a urinary antimicrobial peptide synthesized in the liver
    • Park CH, Valore EV, Waring AJ, Ganz T (2001) Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 276(11):7806-7810
    • (2001) J Biol Chem , vol.276 , Issue.11 , pp. 7806-7810
    • Park, C.H.1    Valore, E.V.2    Waring, A.J.3    Ganz, T.4
  • 46
    • 80053573490 scopus 로고    scopus 로고
    • Iron overload plays a unique role in osteoporosis
    • 9 Sep, 2010, Accessed 9 Sep. 2010
    • Youjia Xu, Pierre Sirois, Kai Li (2010) Iron overload plays a unique role in osteoporosis. [E-letter] Blood (9 Sep. 2010). http://bloodjournal. hematologylibrary.org/content/116/14/2582.full/replyloodjournal-el-524. Accessed 9 Sep. 2010
    • (2010) [E-letter] Blood
    • Xu, Y.1    Sirois, P.2    Li, K.3
  • 48
    • 80053574093 scopus 로고    scopus 로고
    • Hepcidin increases intracellular Ca2+ of osteoblast hFOB1.19 through Ltype Ca2+ channels
    • Xu Y, Li G, Du B, Zhang P, Xiao L, Sirois P, Li K (2011) Hepcidin increases intracellular Ca2+ of osteoblast hFOB1.19 through Ltype Ca2+ channels. Regul Pept 172(1-3):58-61
    • (2011) Regul Pept , vol.172 , Issue.1-3 , pp. 58-61
    • Xu, Y.1    Li, G.2    Du, B.3    Zhang, P.4    Xiao, L.5    Sirois, P.6    Li, K.7
  • 49
    • 84863799042 scopus 로고    scopus 로고
    • Downregulation of ferroportin 1 expression in hFOB1.19 osteoblasts by hepcidin
    • doi:10.1007/s10753-011-9411-8
    • Xu Y, Zhang W, Zhang P, Xiao L, Wang A, Sirois P, Li K (2012) Downregulation of ferroportin 1 expression in hFOB1.19 osteoblasts by hepcidin. Inflammation. doi:10.1007/s10753-011-9411-8
    • (2012) Inflammation
    • Xu, Y.1    Zhang, W.2    Zhang, P.3    Xiao, L.4    Wang, A.5    Sirois, P.6    Li, K.7
  • 50
    • 84857514634 scopus 로고    scopus 로고
    • Increased iron store and its relationship with cardiovascular disease
    • Merono T, Sorroche P, Brites FD (2011) Increased iron store and its relationship with cardiovascular disease. Medicina (B Aires) 71(6):566-572
    • (2011) Medicina (B Aires) , vol.71 , Issue.6 , pp. 566-572
    • Merono, T.1    Sorroche, P.2    Brites, F.D.3
  • 51
    • 0036970185 scopus 로고    scopus 로고
    • Brain iron metabolism and neurodegenerative disorders
    • Sipe JC, Lee P, Beutler E (2002) Brain iron metabolism and neurodegenerative disorders. Dev Neurosci 24(2-3):188-196
    • (2002) Dev Neurosci , vol.24 , Issue.2-3 , pp. 188-196
    • Sipe, J.C.1    Lee, P.2    Beutler, E.3
  • 53
    • 80051635783 scopus 로고    scopus 로고
    • Iron-dependent functions of mitochondria-relation to neurodegeneration
    • Gille G, Reichmann H (2011) Iron-dependent functions of mitochondria-relation to neurodegeneration. J Neural Transm 118(3):349-359
    • (2011) J Neural Transm , vol.118 , Issue.3 , pp. 349-359
    • Gille, G.1    Reichmann, H.2
  • 55
    • 70449529421 scopus 로고    scopus 로고
    • Excess iron inhibits osteoblast metabolism
    • Yamasaki K, Hagiwara H (2009) Excess iron inhibits osteoblast metabolism. Toxicol Lett 191(2-3):211-215
    • (2009) Toxicol Lett , vol.191 , Issue.2-3 , pp. 211-215
    • Yamasaki, K.1    Hagiwara, H.2
  • 57
    • 0025126555 scopus 로고
    • Role of free radicals and catalytic metal ions in human disease: An overview
    • Halliwell B, Gutteridge JM (1990) Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 186:1-85
    • (1990) Methods Enzymol , vol.186 , pp. 1-85
    • Halliwell, B.1    Gutteridge, J.M.2
  • 58
    • 0018263443 scopus 로고
    • The biology of oxygen radicals
    • Fridovich I (1978) The biology of oxygen radicals. Science 201(4359):875-880
    • (1978) Science , vol.201 , Issue.4359 , pp. 875-880
    • Fridovich, I.1
  • 59
    • 34848814178 scopus 로고    scopus 로고
    • Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor-to forkhead box O-mediated transcription
    • Almeida M, Han L, Martin-Millan M, O'Brien CA, Manolagas SC (2007) Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor-to forkhead box O-mediated transcription. J Biol Chem 282(37):27298-27305
    • (2007) J Biol Chem , vol.282 , Issue.37 , pp. 27298-27305
    • Almeida, M.1    Han, L.2    Martin-Millan, M.3    O'Brien, C.A.4    Manolagas, S.C.5
  • 61
    • 42449094897 scopus 로고    scopus 로고
    • Promotion of osteogenesis through beta-catenin signaling by desferrioxamine
    • Qu ZH, Zhang XL, Tang TT, Dai KR (2008) Promotion of osteogenesis through beta-catenin signaling by desferrioxamine. Biochem Biophys Res Commun 370(2):332-337
    • (2008) Biochem Biophys Res Commun , vol.370 , Issue.2 , pp. 332-337
    • Qu, Z.H.1    Zhang, X.L.2    Tang, T.T.3    Dai, K.R.4
  • 65
    • 40649097947 scopus 로고    scopus 로고
    • Effects of colloidal iron overload on renal and hepatic siderosis and the femur in male rats
    • Kudo H, Suzuki S, Watanabe A, Kikuchi H, Sassa S, Sakamoto S (2008) Effects of colloidal iron overload on renal and hepatic siderosis and the femur in male rats. Toxicology 246(2-3):143-147
    • (2008) Toxicology , vol.246 , Issue.2-3 , pp. 143-147
    • Kudo, H.1    Suzuki, S.2    Watanabe, A.3    Kikuchi, H.4    Sassa, S.5    Sakamoto, S.6
  • 67
    • 70449129929 scopus 로고    scopus 로고
    • Iron and menopause: Does increased iron affect the health of postmenopausal women?
    • Jian J, Pelle E, Huang X (2009) Iron and menopause: does increased iron affect the health of postmenopausal women? Antioxid Redox Signal 11(12):2939-2943
    • (2009) Antioxid Redox Signal , vol.11 , Issue.12 , pp. 2939-2943
    • Jian, J.1    Pelle, E.2    Huang, X.3
  • 69
    • 0035896581 scopus 로고    scopus 로고
    • A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
    • Pigeon C, Ilyin G, Courselaud B, Leroyer P, Turlin B, Brissot P, Loreal O (2001) A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 276(11):7811-7819
    • (2001) J Biol Chem , vol.276 , Issue.11 , pp. 7811-7819
    • Pigeon, C.1    Ilyin, G.2    Courselaud, B.3    Leroyer, P.4    Turlin, B.5    Brissot, P.6    Loreal, O.7
  • 70
    • 0035902605 scopus 로고    scopus 로고
    • Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
    • Nicolas G, Bennoun M, Devaux I, Beaumont C, Grandchamp B, Kahn A, Vaulont S (2001) Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2(USF2) knockout mice. Proc Natl Acad Sci USA 98 (15):8780-8785
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.15 , pp. 8780-8785
    • Nicolas, G.1    Bennoun, M.2    Devaux, I.3    Beaumont, C.4    Grandchamp, B.5    Kahn, A.6    Vaulont, S.7
  • 72
    • 0035902586 scopus 로고    scopus 로고
    • Hepcidin: A putative iron-regulatory hormone relevant to hereditary hemochromatosis and the anemia of chronic disease
    • Fleming RE, Sly WS (2001) Hepcidin: a putative iron-regulatory hormone relevant to hereditary hemochromatosis and the anemia of chronic disease. Proc Natl Acad Sci USA 98(15):8160-8162
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.15 , pp. 8160-8162
    • Fleming, R.E.1    Sly, W.S.2
  • 73
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J (2004) Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306(5704):2090-2093
    • (2004) Science , vol.306 , Issue.5704 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.B.4    Donovan, A.5    Ward, D.M.6    Ganz, T.7    Kaplan, J.8
  • 74
    • 33750133047 scopus 로고    scopus 로고
    • Regulation of iron metabolism by hepcidin
    • Nemeth E, Ganz T (2006) Regulation of iron metabolism by hepcidin. Annu Rev Nutr 26:323-342
    • (2006) Annu Rev Nutr , vol.26 , pp. 323-342
    • Nemeth, E.1    Ganz, T.2
  • 75
    • 33644862202 scopus 로고    scopus 로고
    • Iron imports. IV. Hepcidin and regulation of body iron metabolism
    • Ganz T, Nemeth E (2006) Iron imports. IV. Hepcidin and regulation of body iron metabolism. Am J Physiol Gastrointest Liver Physiol 290(2):G199-G203
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , Issue.2
    • Ganz, T.1    Nemeth, E.2
  • 77
    • 24744458603 scopus 로고    scopus 로고
    • Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs
    • Rivera S, Nemeth E, Gabayan V, Lopez MA, Farshidi D, Ganz T (2005) Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs. Blood 106(6):2196-2199
    • (2005) Blood , vol.106 , Issue.6 , pp. 2196-2199
    • Rivera, S.1    Nemeth, E.2    Gabayan, V.3    Lopez, M.A.4    Farshidi, D.5    Ganz, T.6
  • 78
    • 79551649662 scopus 로고    scopus 로고
    • A preliminary report of expression of hepcidin gene in SD rats osteoporosis model
    • Ma Y, Youjia Xu, Wang A et al (2006) A preliminary report of expression of hepcidin gene in SD rats osteoporosis model. Suzhou Univ J Med Sci 26:367-369
    • (2006) Suzhou Univ J Med Sci , vol.26 , pp. 367-369
    • Ma, Y.1    Xu, Y.2    Wang, A.3
  • 79
    • 79551632249 scopus 로고    scopus 로고
    • Increased intracellular iron and mineralization of cultured hFOB 1.19 cells following hepcidin activation through ferroportin-1
    • Zhang P, Xu YJ, Zhao DY, Ma Y, Xiao L, Feng YS, Du BC, Qian ZM, Li K (2010) Increased intracellular iron and mineralization of cultured hFOB 1.19 cells following hepcidin activation through ferroportin-1. Saudi Med J 31(12):1303-1308
    • (2010) Saudi Med J , vol.31 , Issue.12 , pp. 1303-1308
    • Zhang, P.1    Xu, Y.J.2    Zhao, D.Y.3    Ma, Y.4    Xiao, L.5    Feng, Y.S.6    Du, B.C.7    Qian, Z.M.8    Li, K.9
  • 80
    • 84867332222 scopus 로고    scopus 로고
    • Research on relationship between FPN1 content and effect of hepcidin on intracellular calcium and iron change in osteoblasts
    • Ma Y, Xu Y (2010) Research on relationship between FPN1 content and effect of hepcidin on intracellular calcium and iron change in osteoblasts. Bone 47(1):406
    • (2010) Bone , vol.47 , Issue.1 , pp. 406
    • Ma, Y.1    Xu, Y.2
  • 81
    • 33745405978 scopus 로고    scopus 로고
    • Age-associated iron accumulation in bone: Implications for postmenopausal osteoporosis and a new target for prevention and treatment by chelation
    • Liu G, Men P, Kenner GH, Miller SC (2006) Age-associated iron accumulation in bone: implications for postmenopausal osteoporosis and a new target for prevention and treatment by chelation. Biometals 19(3):245-251
    • (2006) Biometals , vol.19 , Issue.3 , pp. 245-251
    • Liu, G.1    Men, P.2    Kenner, G.H.3    Miller, S.C.4
  • 82
    • 33750610853 scopus 로고    scopus 로고
    • Iron loading: A risk factor for osteoporosis
    • Weinberg ED (2006) Iron loading: a risk factor for osteoporosis. Biometals 19(6):633-635
    • (2006) Biometals , vol.19 , Issue.6 , pp. 633-635
    • Weinberg, E.D.1
  • 83
    • 0037071248 scopus 로고    scopus 로고
    • Epidemiological evidence of increased bone mineral density in habitual tea drinkers
    • Wu CH, Yang YC, Yao WJ, Lu FH, Wu JS, Chang CJ (2002) Epidemiological evidence of increased bone mineral density in habitual tea drinkers. Arch Intern Med 162(9):1001-1006
    • (2002) Arch Intern Med , vol.162 , Issue.9 , pp. 1001-1006
    • Wu, C.H.1    Yang, Y.C.2    Yao, W.J.3    Lu, F.H.4    Wu, J.S.5    Chang, C.J.6
  • 84
    • 39349116031 scopus 로고    scopus 로고
    • Therapeutic effects of an oral chelator targeting skeletal tissue damage in experimental postmenopausal osteoporosis in rats
    • Liu G, Men P, Kenner GH, Miller SC (2008) Therapeutic effects of an oral chelator targeting skeletal tissue damage in experimental postmenopausal osteoporosis in rats. Hemoglobin 32(1-2):181-190
    • (2008) Hemoglobin , vol.32 , Issue.1-2 , pp. 181-190
    • Liu, G.1    Men, P.2    Kenner, G.H.3    Miller, S.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.