Identification of the dichotomous role of age-related LCK in calorie restriction revealed by integrative analysis of cDNA microarray and interactome

Age

Volumn 35, Issue 4, 2013, Pages 1045-1060

  Park, Daeui ^a   Lee, Eun Kyeong ^a   Jang, Eun Jee ^a   Jeong, Hyoung Oh ^a   Kim, Byoung Chul ^a   Ha, Young Mi ^b   Hong, Seong Eui ^c   Yu, Byung Pal ^d   Chung, Hae Young ^a  

^a Pusan National University   (South Korea)

^b Dongnam Institute of Radiological and Medical Science   (South Korea)

^c Gwangju Institute of Science and Technology (GIST)   (South Korea)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Aging; Calorie restriction; CDNA microarray; Differentially expressed genes; Interactome; LCK

Indexed keywords

COMPLEMENTARY DNA; GLUCOSE TRANSPORTER 4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYELIN BASIC PROTEIN; N5 (1 IMINOETHYL)ORNITHINE; PENICILLAMINE; PROTEIN KINASE LCK; TRANSCRIPTOME; RNA;

AGE DISTRIBUTION; AGED; AGING; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; CTSS GENE; DNA MICROARRAY; DOWN REGULATION; ENZYME ACTIVITY; GENE; GENE CONTROL; GENE IDENTIFICATION; GENE INTERACTION; GLUT4 GENE; IN VITRO STUDY; IN VIVO STUDY; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN 3 GENE; LCK GENE; MALE; MBP GENE; MOUSE; NDRG1 GENE; NF KAPPAB1ALPHA GENE; NONHUMAN; PLSCR1 GENE; PREDICTION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RAT; RPS6KA3 GENE; SIGNAL TRANSDUCTION; SLC2A4 GENE; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY GENE; UPREGULATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CALORIC INTAKE; CELL CULTURE; COMPARATIVE STUDY; DISEASE MODEL; FISCHER 344 RAT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; METHODOLOGY;

AGING; ANIMALS; CALORIC RESTRICTION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENERGY INTAKE; GENE EXPRESSION REGULATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MALE; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; RATS; RATS, INBRED F344; REAL-TIME POLYMERASE CHAIN REACTION; RNA;

EID: 84886802857     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-012-9426-6     Document Type: Article

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