The molecular mechanism and potential role of heat shock-induced p53 protein accumulation

Molecular and Cellular Biochemistry

Volumn 378, Issue 1-2, 2013, Pages 161-169

  Han, Juqiang ^a,b   Xu, Xiaojie ^b   Qin, Hongzhen ^c   Liu, Anheng ^d   Fan, Zhongyi ^b   Kang, Lei ^b,e   Fu, Jing ^b   Liu, Jiahong ^b   Ye, Qinong ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

^c The 305 Hospital of Chinese PLA   (China)

^d Beijing 307 Hospital   (China)

^e PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

Heat stress; Heat therapy; P53

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45ALPHA; LIGHT CHAIN 3 PROTEIN; MESSENGER RNA; PROTEIN; PROTEIN P53; PUMA PROTEIN; STRATIFIN; UNCLASSIFIED DRUG; LUCIFERASE; TP53 PROTEIN, HUMAN;

ARTICLE; AUTOPHAGY; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA DAMAGE; GENE ACTIVITY; GENE EXPRESSION; GENOTOXICITY; HALF LIFE TIME; HEAT INJURY; HEAT SHOCK; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; IONIZING RADIATION; LIGHT CHAIN; LIVER CANCER; MOLECULAR DYNAMICS; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; ULTRAVIOLET RADIATION; BIOSYNTHESIS; CATHETER ABLATION; GENE EXPRESSION REGULATION; GENETICS; HEAT SHOCK RESPONSE; METABOLISM; PROTEIN STABILITY; REPORTER GENE;

CATHETER ABLATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENES, REPORTER; HALF-LIFE; HEAT-SHOCK RESPONSE; HEP G2 CELLS; HUMANS; LUCIFERASES; PROMOTER REGIONS, GENETIC; PROTEIN STABILITY; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84886772850     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1607-9     Document Type: Article

References (43)

1. Curley SA, Izzo F, Delrio P, Ellis LM, Granchi J, Vallone P, Fiore F, Pignata S, Daniele B, Cremona F (1999) Radiofrequency ablation of unresectable primary and metastatic hepatic malignancies: results in 123 patients. Ann Surg 230:1-8
2. Zerbini A, Pilli M, Laccabue D, Pelosi G, Molinari A, Negri E, Cerioni S, Fagnoni F, Soliani P, Ferrari C (2010) Radiofrequency thermal ablation for hepatocellular carcinoma stimulates autologous NK-cell response. Gastroenterology 138:1931-1942
3. Poulou LS, Ziakas PD, Xila V, Vakrinos G, Malagari K, Syrigos KN, Thanos L (2009) Percutaneous radiofrequency ablation for unresectable colorectal liver metastases: time for shadows to disperse. Rev Recent Clin Trials 4:140-146
4. Lencioni R, Cioni D, Crocetti L, Franchini C, Pina CD, Lera J, Bartolozzi C (2005) Early-stage hepatocellular carcinoma in patients with cirrhosis: long-term results of percutaneous imageguided radiofrequency ablation. Radiology 234:961-967
5. Lees WR, Gillams A (2005) Radiofrequency ablation: other abdominal organs. Abdom Imaging 30:451-455
6. Varshney S, Sewkani A, Sharma S, Kapoor S, Naik S, Sharma A, Patel K (2006) Radiofrequency ablation of unresectable pancreatic carcinoma: feasibility, efficacy and safety. J Pancreas 7:74-78
7. McAchran SE, Lesani OA, Resnick MI (2005) Radiofrequency ablation of renal tumors: past, present, and future. Urology 66:15-22
8. Gervais DA, McGovern FJ, Arellano RS, McDougal WS, Mueller PR (2005) Radiofrequency ablation of renal cell carcinoma: part 1, Indications, results, and role in patient management over a 6-year period and ablation of 100 tumors. Am J Roentgenol 185:64-71
9. Dupuy DE, DiPetrillo T, Gandhi S, Ready N, Ng T, Donat W, Mayo-Smith WW (2006) Radiofrequency ablation followed by conventional radiotherapy for medically inoperable stage I nonsmall cell lung cancer. Chest 129:738-745
10. Solbiati L, Goldberg SN, Ierace T, Livraghi T, Meloni F, Dellanoce M, Sironi S, Gazelle GS (1997) Hepatic metastases: percutaneous radio-frequency ablation with cooled-tip electrodes. Radiology 205:367-373
11. Lindquist S (1986) The heat-shock response. Annu Rev Biochem 55:1151-1191
12. Morimoto RI (1993) Cells in stress: transcriptional activation of heat shock genes. Science 259:1409-1410
13. Blagosklonny MV (2001) Role of the heat shock response and molecular chaperones in oncogenesis and cell death. J Natl Cancer Inst 93:239-240
14. Burns, El Deiry WS (1999) The p53 pathway and apoptosis. J Cell Physiol 181:231-239
15. Sionov RV, Haupt Y (1999) The cellular response to p53: the decision between life and death. Oncogene 18:6145-6157
16. Verschooten L, Declercq L, Garmyn M (2006) Adaptive response of the skin to UVB damage: role of the p53 protein. Int J Cosmet Sci 28:1-7
17. Sharma A, Meena AS, Bhat MK (2010) Hyperthermia-associated carboplatin resistance: differential role of p53, HSF1 and Hsp70 in hepatoma cells. Cancer Sci 101:1186-1193
18. Li Q, Zhao LY, Zheng Z, Yang H, Santiago A, Liao D (2011) Inhibition of p53 by adenovirus type 12 E1B-55K deregulates cell cycle control and sensitizes tumor cells to genotoxic agents. J Virol 85(16):7976-7988
19. Sun L, Zhang G, Li Z, Lei T, Huang C, Song T, Si L (2008) Cellular distribution of tumour suppressor protein p53 and highrisk human papillomavirus (HPV)-18 E6 fusion protein in wildtype p53 cell lines. J Int Med Res 36(5):1015-1021
20. Zhang Z, Chen C, Wang G, Yang Z, San J, Zheng J, Li Q, Luo X, Hu Q, Li Z, Wang D (2011) Aberrant expression of the p53- inducible antiproliferative gene BTG2 in hepatocellular carcinoma is associated with overexpression of the cell cycle-related proteins. Cell Biochem Biophys 61(1):83-91
21. Ding LH, Wang ZY, Yan JH, Yang X, Liu AJ, Qiu WY, Zhu JH, Han JQ, Zhang H, Lin J (2009) Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-blike signaling pathway. J Clin Invest 119:349-361
22. Bustin SA, Beaulieu JF, Huggett J, Jaggi R, Kibenge FS, Olsvik PA, Penning LC, Toegel S (2010) MIQE précis: practical implementation of minimum standard guidelines for fluorescence- based quantitative real-time PCR experiments. BMC Mol Biol 21(11):74
23. Xu X, Fan Z, Kang L, Han J, Jiang C, Zheng X, Zhu Z, Jiao H, Lin J, Jiang K (2013) Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis. J Clin Invest. doi: 10.1172/JCI64265
24. Cheng L, Li J, Han Y, Lin J, Niu C, Zhou Z, Yuan B, Huang K, Li J, Jiang K, Zhang H, Ding L, Xu X, Ye Q (2012) PES1 promotes breast cancer by differentially regulating ERa and ERb. J Clin Invest 122:2857-2870
25. Wang Y, Gao W, Svitkin YV, Chen AP, Cheng YC (2010) DCB-3503, a tylophorine analog, inhibits protein synthesis through a novel mechanism. PLoS One 5(7):e11607
26. Scaffa PM, Vidal CM, Barros N, Gesteira TF, Carmona AK, Breschi L, Pashley DH, Tjäderhane L, Tersariol IL, Nascimento FD, Carrilho MR (2012) Chlorhexidine inhibits the activity of dental cysteine cathepsins. J Dent Res 4:420-425
27. Rashi-Elkeles S, Elkon R, Shavit S, Lerenthal Y, Linhart C, Kupershtein A, Amariglio N, Rechavi G, Shamir R, Shiloh Y (2011) Transcriptional modulation induced by ionizing radiation: p53 remains a central player. Mol Oncol 8:336-348
28. Pustisek N, Situm M (2011) UV-radiation, apoptosis and skin. Coll Antropol 35(2):339-341
29. Taylor WR, Stark GR (2001) Regulation of the G2/M transition by p53. Oncogene 20:1803-1815
30. Scherz-Shouval R, Weidberg H, Gonen C, Wilder S, Elazar Z, Oren M (2010) p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation. Proc Natl Acad Sci USA 107(43):18511-18516
31. Qin LX, Tang ZY (2002) The prognostic significance of clinical and pathological features in hepatocellular carcinoma. World J Gastroenterol 8:193-199
32. Nikfarjam M, Muralidharan V, Christophi C (2005) Mechanisms of focal heat destruction of liver tumors. J Surg Res 127:208-223
33. Burns TF, El-Deiry WS (1999) The p53 pathway and apoptosis. J Cell Physiol 181(2):231-239
34. Martindale JL, Holbrook NJ (2002) Cellular response to oxidative stress: signaling for suicide and survival. J Cell Physiol 192:1-15
35. Zilfou JT, Lowe SW (2009) Tumor suppressive functions of p53. Cold Spring Harb Perspect Biol 1(5):a001883
36. Vilborg A, Wilhelm MT, Wiman KG (2010) Regulation of tumor suppressor p53 at the RNA level. J Mol Med 88:645-652
37. Raman V, Martensen SA, Reisman D, Evron E, Odenwald WF, Jaffee E, Marks J, Sukumar S (2000) Compromised HOXA5 function can limit p53 expression in human breast tumours. Nature 405:974-978
38. Liu H, Lu ZG, Miki Y, Yoshida K (2007) Protein Kinase C d induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage. Mol Cell Biol 27(24):8480-8491
39. Phan RT, Dalla-Favera R (2004) The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature 432:635-639
40. Noda A, Toma-Aiba Y, Fujiwara Y (2000) A unique, short sequence determines p53 gene basal and UV-inducible expression in normal human cells. Oncogene 19:21-31
41. Sun X, Shimizu H, Yamamoto KI (1995) Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression. Mol Cell Biol 15(8):4489-4496
42. Lynch CJ, Milner J (2006) Loss of one p53 allele results in fourfold reduction of p53 mRNA and protein: a basis for p53 haploinsufficiency. Oncogene 25:3463-3470
43. Shu KX, Li B, Wu LX (2007). The p53 network: p53 and its downstream genes. Colloids Surf B Biointerfaces 55(1):10-18