Chlorhexidine inhibits the activity of dental cysteine cathepsins

Journal of Dental Research

Volumn 91, Issue 4, 2012, Pages 420-425

  Scaffa, P M C ^a   Vidal, C M P ^a   Barros, N ^b   Gesteira, T F ^b   Carmona, A K ^b   Breschi, L ^c   Pashley, D H ^d   Tjaderhane L ^e   Tersariol, I L S ^b,f   Nascimento, F D ^g   Carrilho, M R ^g  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF TRIESTE   (Italy)

^d MEDICAL COLLEGE OF GEORGIA   (United States)

^e UNIVERSITY OF OULU   (Finland)

^f UNIVERSIDADE DE MOGI DAS CRUZES   (Brazil)

^g Universidade Bandeirante de Sao Paulo   (Brazil)

Author keywords

chlorhexidine; collagen; cysteine cathepsins; degradation; dentin; proteolytic activity

Indexed keywords

BENZYLOXYCARBONYL PHENYLALANYLARGININE 4 METHYLCOUMARYL 7 AMIDE; BENZYLOXYCARBONYL-PHENYLALANYLARGININE-4-METHYLCOUMARYL-7-AMIDE; CATHEPSIN; CATHEPSIN B; CATHEPSIN K; CATHEPSIN L; CHLORHEXIDINE; CHLORHEXIDINE GLUCONATE; COUMARIN DERIVATIVE; CTSB PROTEIN, HUMAN; CTSK PROTEIN, HUMAN; CTSL1 PROTEIN, HUMAN; CYSTEINE PROTEINASE INHIBITOR; DIAGNOSTIC AGENT; DIPEPTIDE; DRUG DERIVATIVE; ENZYME INHIBITOR; FLUORESCENT DYE; LEUCINE; MATRIX METALLOPROTEINASE; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; RECOMBINANT PROTEIN;

ADULT; ARTICLE; CHEMICAL STRUCTURE; DENTIN; DOSE RESPONSE; DRUG ANTAGONISM; ENZYMOLOGY; HUMAN; HYDROLYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; SPECTROFLUOROMETRY;

ADULT; CATHEPSIN B; CATHEPSIN K; CATHEPSIN L; CATHEPSINS; CHLORHEXIDINE; COUMARINS; CYSTEINE PROTEINASE INHIBITORS; DENTIN; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLUORESCENT DYES; HUMANS; HYDROLYSIS; LEUCINE; MATRIX METALLOPROTEINASES; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; YOUNG ADULT;

EID: 84859074784     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034511435329     Document Type: Article

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