Novel biotinylated chitosan-graft-polyethyleneimine copolymer as a targeted non-viral vector for anti-EGF receptor siRNA delivery in cancer cells

International Journal of Pharmaceutics

Volumn 456, Issue 2, 2013, Pages 408-416

  Darvishi, Mohammad H ^a   Nomani, Alireza ^b   Amini, Mohsen ^c   Shokrgozar, Mohammad A ^d   Dinarvand, Rassoul ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ZANJAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d PASTEUR INSTITUTE OF IRAN   (Iran)

Author keywords

Biotinylation; Chitosan graft polyethyleneimine; Epidermal growth factor receptor; Gene silencing; siRNA delivery; Tumor targeting delivery

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; CHITOSAN GRAFT POLYETHYLENEIMINE; COPOLYMER; EPIDERMAL GROWTH FACTOR RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; COMPLEX FORMATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY TEST; FEMALE; FLOW CYTOMETRY; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTERNALIZATION; NITROBLUE TETRAZOLIUM TEST; NONVIRAL GENE DELIVERY SYSTEM; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REAL TIME POLYMERASE CHAIN REACTION; SYNTHESIS; ZETA POTENTIAL;

BIOTINYLATION; CHITOSAN-GRAFT-POLYETHYLENEIMINE; EPIDERMAL GROWTH FACTOR RECEPTOR; GENE SILENCING; SIRNA DELIVERY; TUMOR-TARGETING DELIVERY;

BIOTINYLATION; CELL SURVIVAL; CHITOSAN; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE TARGETING; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HELA CELLS; HUMANS; POLYETHYLENEIMINE; POLYMERS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, SMALL INTERFERING;

EID: 84886727460     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.08.069     Document Type: Article

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