Protection of a ceramide synthase 2 null mouse from drug-induced liver injury role of gap junction dysfunction and connexin 32 mislocalization

Journal of Biological Chemistry

Volumn 288, Issue 43, 2013, Pages 30904-30916

  Park, Woo Jae ^a,b   Park, Joo Won ^a,c   Erez Roman, Racheli ^a,d   Kogot Levin, Aviram ^a,d   Bame, Jessica R ^f   Tirosh, Boaz ^e   Saada, Ann ^d   Merrill Jr , Alfred H ^f   Pewzner Jung, Yael ^a   Futerman, Anthony H ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b Gachon University   (South Korea)

^c Ewha Womans University School of Medicine   (South Korea)

^d HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^e HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^f GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL CHANGES; CERAMIDE SYNTHASE; D-GALACTOSAMINE; DETERGENT-RESISTANT MEMBRANES; GAP JUNCTION PROTEINS; LYSOSOMAL DEGRADATION; MEMBRANE PROPERTIES; RECOMBINANT ADENO-ASSOCIATED VIRUS;

MAMMALS; PROTEINS; TOXICITY; VIRUSES;

CERAMIDES;

CARBON TETRACHLORIDE; CERAMIDE; CERAMIDE SYNTHETASE 2; CONNEXIN 32; GALACTOSAMINE; GLUTATHIONE; MULTIDRUG RESISTANCE PROTEIN 4; PARACETAMOL; SYNTHETASE; THIOACETAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE RESISTANCE; GAP JUNCTION; LIVER CELL; LIVER PROTECTION; LYSOSOME; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TOXIC HEPATITIS;

CERAMIDE; CERAMIDE SYNTHASE; DRUG RESISTANCE; LIVER INJURY; MEMBRANE LIPIDS; SPHINGOLIPID;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; CARBON TETRACHLORIDE; CARBON TETRACHLORIDE POISONING; CERAMIDES; CONNEXINS; DRUG-INDUCED LIVER INJURY; GALACTOSAMINE; GAP JUNCTIONS; GLUTATHIONE; HEPATOCYTES; MEMBRANE MICRODOMAINS; MICE; MICE, MUTANT STRAINS; SPHINGOSINE N-ACYLTRANSFERASE;

EID: 84886687848     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.448852     Document Type: Article

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