Ceramide synthases at the centre of sphingolipid metabolism and biology

Biochemical Journal

Volumn 441, Issue 3, 2012, Pages 789-802

  Mullen, Thomas D ^a   Hannun, Yusuf A ^a   Obeid, Lina M ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

Ceramide; Ceramide synthase (CerS); De novo sphingolipid synthesis; Salvage pathway; Sphingolipid; Sphingosine

Indexed keywords

ACYL COENZYME A; CAMPTOTHECIN; CERAMIDE; CERAMIDE SYNTHASE; DAUNORUBICIN; DOXORUBICIN; ENZYME; ETOPOSIDE; FENRETINIDE; FLUDARABINE; INOSTAMYCIN; ISOENZYME; MESSENGER RNA; OXALIPLATIN; SEMAXANIB; SPHINGOLIPID; SPHINGOSINE; UNCLASSIFIED DRUG; VINCRISTINE;

APOPTOSIS; AUTONOMIC NEUROPATHY; BREAST CANCER; CELL FUNCTION; CELLULAR STRESS SIGNAL; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SYNTHESIS; GENOMICS; HEAD AND NECK CANCER; HUMAN; KERATINOCYTE; KNOCKOUT MOUSE; LIPID METABOLISM; LIPOGENESIS; LIVER DYSFUNCTION; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROCESSING; RADIOSENSITIVITY; REVIEW; TESTIS; TISSUE DISTRIBUTION;

ANIMALS; BIOLOGY; CERAMIDES; HUMANS; LIPID METABOLISM; MAMMALS; MODELS, BIOLOGICAL; OXIDOREDUCTASES; SPHINGOLIPIDS;

MAMMALIA; METAZOA; SPHINGOIDEA;

EID: 84855918312     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111626     Document Type: Review

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