Citrus flavanones enhance carotenoid uptake by intestinal Caco-2 cells

Food and Function

Volumn 4, Issue 11, 2013, Pages 1625-1631

  Claudie, Dhuique Mayer ^a   Alexandrine, During ^b   Bertrand, Caporiccio ^c   Franck, Tourniaire ^d   Marie Josephe, Amiot ^d  

^a UMR QUALISUD   (France)

^b Physiopathologie des Maladies Osseuses Inflammatoires   (France)

^c UNIV MONTPELLIER   (France)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CACO-2 CELLS; CELLULAR UPTAKE; CITRUS FLAVANONES; CITRUS JUICES; ENHANCING EFFECT; FRUITS AND VEGETABLES; HEALTH BENEFITS; PHYTOCHEMICALS;

BIOCHEMISTRY; CELLS; FLAVONOIDS; FRUIT JUICES; IRON;

ASCORBIC ACID;

CAROTENOID; FLAVONOID; IRON;

ARTICLE; BIOAVAILABILITY; CACO 2 CELL LINE; CITRUS; HUMAN; INTESTINE; INTESTINE ABSORPTION; METABOLISM;

BIOLOGICAL AVAILABILITY; CACO-2 CELLS; CAROTENOIDS; CITRUS; FLAVONOIDS; HUMANS; INTESTINAL ABSORPTION; INTESTINES; IRON;

EID: 84886655087     PISSN: 20426496     EISSN: 2042650X     Source Type: Journal    
DOI: 10.1039/c3fo60212e     Document Type: Article

References (40)

1. A. Bendich J. A. Olson Biological actions of carotenoids FASEB J. 1989 3 1927 1932
2. W. Stahl H. Sies Bioactivity and protective effects of natural carotenoids Biochim. Biophys. Acta, Bioenerg. 2005 1740 101 107
3. J. W. Lampe Health effects of vegetables and fruit: assessing mechanisms of action in human experimental studies Am. J. Clin. Nutr. 1999 70 suppl. 3 475S 490S
4. D. A. Garrett M. L. Failla R. J. Sarama Estimation of carotenoid bioavailability from fresh stir-fried vegetables using an in vitro digestion/Caco-2 cell culture model J. Nutr. Biochem. 2000 11 574 580
5. R. H. Liu Potential synergy of phytochemicals in cancer prevention: mechanism of action J. Nutr. 2004 134 3479s 3485s
6. C. Dhuique-Mayer P. Borel E. Reboul B. Caporiccio P. Besancon M. J. Amiot Beta-cryptoxanthin from citrus juices: assessment of bioaccessibility using an in vitro digestion/Caco-2 cell culture model Br. J. Nutr. 2007 97 883 890
7. A. During E. H. Harrison An in vitro model to study the intestinal absorption of carotenoids Food Res. Int. 2005 38 1001 1008
8. A. During G. Albaugh J. C. Smith, Jr Characterization of beta-carotene 15,15′-dioxygenase activity in TC7 clone of human intestinal cell line Caco-2 Biochem. Biophys. Res. Commun. 1998 249 467 474
9. E. Reboul L. Abou C. Mikail O. Ghiringhelli M. Andre H. Portugal D. Jourdheuil-Rahmani M. J. Amiot D. Lairon P. Borel Lutein transport by Caco-2 TC-7 cells occurs partly by a facilitated process involving the scavenger receptor class B type I (SR-BI) Biochem. J. 2005 387 455 461
10. A. During H. D. Dawson E. H. Harrison Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 cells treated with ezetimibe J. Nutr. 2005 135 2305 2312
11. A. van Bennekum M. Werder S. T. Thuahnai C. H. Han P. Duong D. L. Williams P. Wettstein G. Schulthess M. C. Phillips H. Hauser Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol Biochemistry 2005 44 4517 4525
12. H. Van den Berg Carotenoid interactions Nutr. Rev. 1999 57 1 10
13. A. During M. M. Hussain D. W. Morel E. H. Harrison Carotenoid uptake and secretion by caco2 cells:carotene isomer selectivity and carotenoid interactions J. Lipid Res. 2002 43 1086 1095
14. J. Riedl J. Linseisen J. Hoffmann G. Wolfram Some dietary fibers reduce the absorption of carotenoids in women J. Nutr. 1999 129 2170 2176
15. M. Richelle M. Enslen C. Hager M. Groux I. Tavazzi et al., Both free and esterified plant sterols reduce cholesterol absorption and the bioavailability of beta-carotene and alpha-tocopherol in normocholesterolemic humans Am. J. Clin. Nutr. 2004 80 171 177
16. M. Raju R. Lakshminarayana T. P. Krishnakantha V. Baskaran Micellar oleic and eicosapentaenoic acid but not linoleic acid influences the beta-carotene uptake and its cleavage into retinol in rats Mol. Cell. Biochem. 2006 288 7 15
17. T. Sugawara M. Kushiro H. Zhang E. Nara H. Ono A. Nagao Lysophosphatidylcholine enhances carotenoid uptake from mixed micelles by Caco-2 human intestinal cells J. Nutr. 2001 131 2921 2927
18. C. Dhuique-Mayer C. Caris-Veyrat P. Ollitrault F. Curk M. J. Amiot Varietal and interspecific influence on micronutrient contents in citrus from the Mediterranean area J. Agric. Food Chem. 2005 53 2140 2145
19. E. Reboul S. Thap F. Tourniaire M. Andre C. Juhel S. Morange M. J. Amiot D. Lairon P. Borel Differential effect of dietary antioxidant classes (carotenoids, polyphenols, vitamins C and E) on lutein absorption Br. J. Nutr. 2007 97 440 446
20. P. Rapisarda A. Tomaino R. Lo Cascio F. Bonina A. De Pasquale A. Saija Antioxydant effectiveness as influenced by phenolic content of fresh orange juices J. Agric. Food Chem. 1999 47 4718 4723
21. V. Tyssandier E. Reboul J. F. Dumas C. Bouteloup-Demange M. Armand J. Marcand M. Sallas P. Borel Processing of vegetable-borne carotenoids in the human stomach and duodenum Am. J. Physiol.: Gastrointest. Liver Physiol. 2003 284 G913 G923
22. S. Salvini M. Charbonnier C. Defoort C. Alquier D. Lairon Functional characterization of three clones of the human intestinal Caco-2 cell line for dietary lipid processing Br. J. Nutr. 2002 87 211 217
23. C. Manach G. Williamson C. Morand A. Scalbert C. Remesy Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies Am. J. Clin. Nutr. 2005 81 230S 242S
24. C. Manach A. Scalbert C. Morand C. Remesy L. Jimenez Polyphenols: food sources and bioavailability Am. J. Clin. Nutr. 2004 79 727 747
25. W. Brand P. A. van der Wel M. J. Rein D. Barron G. Williamson P. J. van Bladeren I. M. Rietjens Metabolism and transport of the citrus flavonoid hesperetin in Caco-2 cell monolayers Drug Metab. Dispos. 2008 36 1794 1802
26. J. Londono-Londono V. R. Lima C. Jaramillo T. Creczynski-Pasa Hesperidin and hesperetin membrane interaction: understanding the role of 7-O-glycoside moiety in flavonoids Arch. Biochem. Biophys. 2010 499 6 16
27. A. Saija M. Scalese M. Lanza D. Marzullo F. Bonina F. Castelli Flavonoids as antioxidant agents: importance of their interaction with biomembranes Free Radical Biol. Med. 1995 19 481 486
28. H. Serra T. Mendes M. R. Bronze A. L. Simplicio Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones Bioorg. Med. Chem. 2008 16 4009 4018
29. P. Tammela L. Laitinen A. Galkin T. Wennberg R. Heczko H. Vuorela J. P. Slotte P. Vuorela Permeability characteristics and membrane affinity of flavonoids and alkyl gallates in Caco-2 cells and in phospholipid vesicles Arch. Biochem. Biophys. 2004 425 193 199
30. 2+ ions: implications for their antioxidant properties Biochem. J. 1998 330 1173 1176
31. P. Sestili G. Diamantini A. Bedini L. Cerioni I. Tommasini G. Tarzia O. Cantoni Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism Biochem. J. 2002 364 121 128
32. M. T. Fernandez M. L. Mira M. H. Florencio K. R. Jennings Iron and copper chelation by flavonoids: an electrospray mass spectrometry study J. Inorg. Biochem. 2002 92 105 111
33. L. Mira M. T. Fernandez M. Santos R. Rocha M. H. Florencio K. R. Jennings Interactions of flavonoids with iron and copper ions: a mechanism for their antioxidant activity Free Radical Res. 2002 36 1199 1208
34. A. Bengtsson N. Scheers T. Andlid M. L. Alminger A. S. Sandberg U. Svanberg Impaired uptake of beta-carotene by Caco-2 human intestinal cells in the presence of iron Int. J. Food Sci. Nutr. 2009 60 suppl. 5 125 135
35. M. N. Garcia-Casal M. Layrisse L. Solano M. A. Baron F. Arguello D. Llovera J. Ramirez I. Leets E. Tropper Vitamin A and beta-carotene can improve nonheme iron absorption from rice, wheat and corn by humans J. Nutr. 1998 128 646 650
36. S. R. Lynch R. J. Stoltzfus Iron and ascorbic acid: proposed fortification levels and recommended iron compounds J. Nutr. 2003 133 2978s 2984s
37. J. D. Cook M. B. Reddy Effect of ascorbic acid intake on nonheme-iron absorption from a complete diet Am. J. Clin. Nutr. 2001 73 93 98
38. M. Shah I. J. Griffin C. H. Lifschitz S. A. Abrams Effect of orange and apple juices on iron absorption in children Am. J. Dis. Child. 2003 157 1232 1236
39. D. Ballot R. D. Baynes T. H. Bothwell M. Gillooly et al., The effects of fruit juices and fruits on the absorption of iron from a rice meal Br. J. Nutr. 1987 57 331 343
40. F. Boato G. M. Wortley R. H. Liu R. P. Glahn Red grape juice inhibits iron availability: Application of an in vitro digestion/Caco-2 cell model J. Agric. Food Chem. 2002 50 6935 6938