Insights into aurora-A kinase activation using unnatural amino acids incorporated by chemical modification

ACS Chemical Biology

Volumn 8, Issue 10, 2013, Pages 2184-2191

  Rowan, Fiona C ^a,b   Richards, Meirion ^a   Bibby, Rachel A ^b   Thompson, Andrew ^a   Bayliss, Richard ^a,c   Blagg, Julian ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b Division of Structural Biology   (United Kingdom)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AURORA A KINASE;

AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL MODIFICATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; PHOSPHORYLATION; X RAY CRYSTALLOGRAPHY;

AMINO ACIDS; AURORA KINASE A; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HUMANS; MODELS, MOLECULAR; PHOSPHORYLATION;

EID: 84886573218     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400425t     Document Type: Article

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