Distinct tyrosine phosphorylation sites in JAK3 kinase domain positively and negatively regulate its enzymatic activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 25, 1997, Pages 13850-13855

  Zhou, Yong Jie ^a   Hanson, Eric P ^a   Chen, Yi Qing ^a   Magnuson, Kelly ^c   Chen, Min ^a   Swann, Patrick G ^a   Wange, Ronald L ^b   Changelian, Paul S ^c   O'Shea, John J ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; MUTANT PROTEIN; PHOSPHOTRANSFERASE; PROTEIN TYROSINE KINASE; TYROSINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL GROWTH; ENZYME ACTIVITY; ENZYME SUBSTRATE; GROWTH REGULATION; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; COS CELLS; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; ENZYME ACTIVATION; JANUS KINASE 3; MILK PROTEINS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; POINT MUTATION; PROTEIN-TYROSINE KINASES; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TYROSINE;

ANIMALIA; JANUS;

EID: 0031444188     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.25.13850     Document Type: Article

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