Metabolic pathways recruited in the production of a recombinant enveloped virus: Mining targets for process and cell engineering

Metabolic Engineering

Volumn 20, Issue , 2013, Pages 131-145

  Rodrigues, A F ^a,b   Formas Oliveira, A S ^a   Bandeira, V S ^a   Alves, P M ^a,b   Hu, W S ^c   Coroadinha, A S ^a,b  

^a INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLÓGICA   (Portugal)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^c University of Minnesota   (United States)

Author keywords

Cell engineering; Mammalian cell culture; Media design; Metabolomics; Recombinant enveloped virus; Transcriptomics

Indexed keywords

AMINES; AMINO ACIDS; BIOCHEMISTRY; BIOSYNTHESIS; CELL CULTURE; CELL ENGINEERING; ENZYMES; GENE EXPRESSION; MACHINERY; PEPTIDES; PHYSIOLOGY; PLANTS (BOTANY); PRODUCTIVITY; VIRUSES;

CENTRAL CARBON METABOLISMS; ENVELOPED VIRUS; GLUTATHIONE BIOSYNTHESIS; MAMMALIAN CELL CULTURE; METABOLOMICS; PENTOSE PHOSPHATE PATHWAY; TRANSCRIPTIONAL PROFILING; TRANSCRIPTOMICS;

METABOLISM;

AMINO ACID; POLYAMINE; TRANSCRIPTOME;

AMINO ACID METABOLISM; ARTICLE; BIOSYNTHESIS; CARBOHYDRATE METABOLISM; CARBON METABOLISM; CATABOLISM; CELL ENGINEERING; CELL GROWTH; CELL LINE; CHOLESTEROL SYNTHESIS; ENERGY METABOLISM; FUNCTIONAL GENOMICS; GENE EXPRESSION; GENOME; GLUTATHIONE METABOLISM; HUMAN; LIPID METABOLISM; METABOLIC ENGINEERING; METABOLISM; NUCLEOTIDE METABOLISM; PENTOSE PHOSPHATE CYCLE; PHENOTYPE; PRIORITY JOURNAL; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; VIRUS RECOMBINANT;

MAMMALIA;

CELL ENGINEERING; MAMMALIAN CELL CULTURE; MEDIA DESIGN; METABOLOMICS; RECOMBINANT ENVELOPED VIRUS; TRANSCRIPTOMICS;

ANIMALS; CELL ENGINEERING; HEK293 CELLS; HUMANS; LEUKEMIA VIRUS, GIBBON APE; LEUKEMIA VIRUS, MURINE; MICE; RETROVIRIDAE INFECTIONS;

EID: 84886481436     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2013.10.001     Document Type: Article

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