Generation of serum-stabilized retroviruses: Reduction of α1,3gal-epitope synthesis in a murine NIH3T3-derived packaging cell line by expression of chimeric glycosyltransferases

Metabolic Engineering

Volumn 7, Issue 3, 2005, Pages 221-228

  Hansen, Wiebke ^a   Grabenhorst, Eckart ^a   Nimtz, Manfred ^a   Müller, Katja ^a   Conradt, Harald S ^a   Wirth, Manfred ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

gal epitope; Gycosyltransferase; Packaging cell line; Retrovirus

Indexed keywords

BIOSYNTHESIS; CATALYSIS; CELLS; ENZYMES; GENES; REDUCTION;

GLYCOSYLATION; HUMAN SERA; RETROVIRUSES; SERUM STABILITY;

VIRUSES;

ALPHA1,3 GALACTOSYLTRANSFERASE; ALPHA2,3 SIALYLTRANSFERASE; EPITOPE; GALACTOSYLTRANSFERASE; GLYCAN DERIVATIVE; GLYCOSYLTRANSFERASE; RETROVIRUS VECTOR; SIALYLTRANSFERASE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CELL LINE; CHIMERA; CONTROLLED STUDY; GLYCOSYLATION; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR STABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SYNTHESIS; VIRAL GENE THERAPY;

ALPHA-GALACTOSIDASE; ANIMALS; GLYCOSYLTRANSFERASES; MICE; NIH 3T3 CELLS; RETROVIRIDAE; SERUM; VIRUS ASSEMBLY; VIRUS REPLICATION;

MURINAE; UNIDENTIFIED RETROVIRUS;

EID: 18844390023     PISSN: 10967176     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymben.2005.02.004     Document Type: Article

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