Genetic engineering of recombinant glycoproteins and the glycosylation pathway in mammalian host cells

Glycoconjugate Journal

Volumn 16, Issue 2, 1999, Pages 81-97

  Grabenhorst, Eckart ^a   Schlenke, Peter ^a   Pohl, Susanne ^a   Nimtz, Manfred ^a   Conradt, Harald S ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Glycosylation engineering; Host cell specificity; Human fucosyltransferases; Human sialyltransferases; N and O glycosylation; Recombinant glycoprotein expression

Indexed keywords

ALTEPLASE; FUCOSYLTRANSFERASE; GLYCOPROTEIN; GLYCOSYLTRANSFERASE; OLIGOSACCHARIDE; RECOMBINANT ANTIBODY; RECOMBINANT BETA INTERFERON; RECOMBINANT INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 6; RECOMBINANT PROTEIN; SIALYLTRANSFERASE; SYNTHETASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; BACULOVIRUS; CARBOHYDRATE ANALYSIS; CHO CELL; EXPRESSION VECTOR; FUCOSYLATION; GENETIC ENGINEERING; GENETIC TRANSFECTION; GOLGI COMPLEX; HOST CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; REVIEW; SIALYLATION; SITE DIRECTED MUTAGENESIS; TISSUE SPECIFICITY;

ANIMALS; CARBOHYDRATE SEQUENCE; CELL LINE; GLYCOPROTEINS; GLYCOSYLATION; GLYCOSYLTRANSFERASES; HUMANS; MAMMALS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN ENGINEERING; RECOMBINANT PROTEINS;

ANIMALIA; MAMMALIA; UNIDENTIFIED BACULOVIRUS;

EID: 0032848329     PISSN: 02820080     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026466408042     Document Type: Review

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