-
1
-
-
84886307000
-
-
Cancer Facts & Figures , A.C. Society, Editor. 2009: Atlanta, GA.
-
Cancer Facts & Figures 2009, A.C. Society, Editor. 2009: Atlanta, GA.
-
(2009)
-
-
-
2
-
-
0036222963
-
Systematic review of first-line chemotherapy for newly diagnosed postoperative patients with stage II, III, or IV epithelial ovarian cancer
-
Covens A, Carey M, Bryson P et al. Systematic review of first-line chemotherapy for newly diagnosed postoperative patients with stage II, III, or IV epithelial ovarian cancer. Gynecol Oncol 2002; 85(1): 71-80.
-
(2002)
Gynecol Oncol
, vol.85
, Issue.1
, pp. 71-80
-
-
Covens, A.1
Carey, M.2
Bryson, P.3
-
3
-
-
0032005629
-
Analysis of failures after negative secondlook in patients with advanced ovarian cancer: an Italian multicenter study
-
Gadducci A, Sartori E, Maggino T et al. Analysis of failures after negative secondlook in patients with advanced ovarian cancer: an Italian multicenter study. Gynecol Oncol 1998; 68: 150-155.
-
(1998)
Gynecol Oncol
, vol.68
, pp. 150-155
-
-
Gadducci, A.1
Sartori, E.2
Maggino, T.3
-
4
-
-
0028856381
-
Proportion of breast cancer cases in the United States explained by well-established risk factors
-
Madigan MP, Ziegler RG, Benichou J et al. Proportion of breast cancer cases in the United States explained by well-established risk factors. J Natl Cancer Inst 1995; 87(22): 1681-1685.
-
(1995)
J Natl Cancer Inst
, vol.87
, Issue.22
, pp. 1681-1685
-
-
Madigan, M.P.1
Ziegler, R.G.2
Benichou, J.3
-
5
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994; 266(5182): 66-71.
-
(1994)
Science
, vol.266
, Issue.5182
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
-
6
-
-
0006713602
-
Identification of the breast cancer susceptibility gene BRCA2
-
Wooster R, Bignell G, Lancester J et al. Identification of the breast cancer susceptibility gene BRCA2. Nature 1995; 378(6559): 789-792.
-
(1995)
Nature
, vol.378
, Issue.6559
, pp. 789-792
-
-
Wooster, R.1
Bignell, G.2
Lancester, J.3
-
7
-
-
0037130889
-
Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program
-
Brose MS, Rebbeck TR, Calzone KA et al. Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program. J Natl Cancer Inst 2002; 94(18): 1365-1372.
-
(2002)
J Natl Cancer Inst
, vol.94
, Issue.18
, pp. 1365-1372
-
-
Brose, M.S.1
Rebbeck, T.R.2
Calzone, K.A.3
-
8
-
-
0037130887
-
the Breast Cancer Linkage, Cancer incidence in BRCA1 mutation carriers
-
Thompson D, D.F. Easton, and C. the Breast Cancer Linkage, Cancer incidence in BRCA1 mutation carriers. J Natl Cancer Inst 2002; 94(18): 1358-1365.
-
(2002)
J Natl Cancer Inst
, vol.94
, Issue.18
, pp. 1358-1365
-
-
Thompson, D.1
Easton, D.F.2
-
9
-
-
0037685164
-
Breast and ovarian cancer
-
Wooster R, Weber BL. Breast and ovarian cancer. N Engl J Med 2003; 348(23): 2339-2347.
-
(2003)
N Engl J Med
, vol.348
, Issue.23
, pp. 2339-2347
-
-
Wooster, R.1
Weber, B.L.2
-
10
-
-
0035098503
-
Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer
-
Risch HA, McLaughlin JR, Cole DEC et al. Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. Am J Hum Genet 2001; 68(3): 700-710.
-
(2001)
Am J Hum Genet
, vol.68
, Issue.3
, pp. 700-710
-
-
Risch, H.A.1
McLaughlin, J.R.2
Cole, D.E.C.3
-
11
-
-
1642554820
-
One in 10 ovarian cancer patients carry germ line BRCA1 or BRCA2 mutations: results of a prospective study in Southern Sweden
-
Malander S, Ridderheim M, Masback A et al. One in 10 ovarian cancer patients carry germ line BRCA1 or BRCA2 mutations: results of a prospective study in Southern Sweden. Eur J Cancer 2004; 40(3): 422-428.
-
(2004)
Eur J Cancer
, vol.40
, Issue.3
, pp. 422-428
-
-
Malander, S.1
Ridderheim, M.2
Masback, A.3
-
12
-
-
0042338757
-
Hereditary ovarian cancer in Poland
-
Menkiszak J, Gronwald J, Gorski B et al. Hereditary ovarian cancer in Poland. Int J Cancer 2003; 106(6): 942-945.
-
(2003)
Int J Cancer
, vol.106
, Issue.6
, pp. 942-945
-
-
Menkiszak, J.1
Gronwald, J.2
Gorski, B.3
-
13
-
-
29144509766
-
BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases
-
Pal T, Permuth-Wey J, Betts JA et al. BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases. Cancer 2005; 104(12): 2807-2816.
-
(2005)
Cancer
, vol.104
, Issue.12
, pp. 2807-2816
-
-
Pal, T.1
Permuth-Wey, J.2
Betts, J.A.3
-
14
-
-
34250358742
-
Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinoma
-
Parikh RA, White JS, Huang X et al. Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinoma. Genes Chromosomes Cancer 2007; 46: 761-775.
-
(2007)
Genes Chromosomes Cancer
, vol.46
, pp. 761-775
-
-
Parikh, R.A.1
White, J.S.2
Huang, X.3
-
15
-
-
18544389716
-
Low-penetrance susceptibility to breast cancer due to CHEK2()1100delC in noncarriers of BRCA1 or BRCA2 mutations
-
Meijers-Heijboer H, van den Ouwelan A, Klijn J et al. Low-penetrance susceptibility to breast cancer due to CHEK2()1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet 2002; 31: 55-59.
-
(2002)
Nat Genet
, vol.31
, pp. 55-59
-
-
Meijers-Heijboer, H.1
van den Ouwelan, A.2
Klijn, J.3
-
16
-
-
0036146312
-
Distinct functions of BRCA1 and BRCA2 in double-strand break repair
-
Liu Y, West S. Distinct functions of BRCA1 and BRCA2 in double-strand break repair. Breast Cancer Res 2002; 4(1): 9-13.
-
(2002)
Breast Cancer Res
, vol.4
, Issue.1
, pp. 9-13
-
-
Liu, Y.1
West, S.2
-
17
-
-
14444277477
-
BRCA2 Is required for embryonic cellular proliferation in the mouse
-
Suzuki A, de la Pompa JK, Hakem R et al. BRCA2 Is required for embryonic cellular proliferation in the mouse. Genes Dev 1997; 11: 1242-1252.
-
(1997)
Genes Dev
, vol.11
, pp. 1242-1252
-
-
Suzuki, A.1
de la Pompa, J.K.2
Hakem, R.3
-
18
-
-
0035799597
-
A targeted mouse BRCA1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage
-
Hohenstein P, Kleiman MF, Breukel C et al. A targeted mouse BRCA1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage. Oncogene 2001; 20: 2544-2550.
-
(2001)
Oncogene
, vol.20
, pp. 2544-2550
-
-
Hohenstein, P.1
Kleiman, M.F.2
Breukel, C.3
-
19
-
-
0034213735
-
Gross chromosomal rearrangements and genetic exchange between non-homologous chromosomes following BRCA2 inactivation
-
Yu VP, Koehler M, Steinlein C et al. Gross chromosomal rearrangements and genetic exchange between non-homologous chromosomes following BRCA2 inactivation. Genes Dev 2000; 14: 1400-1406.
-
(2000)
Genes Dev
, vol.14
, pp. 1400-1406
-
-
Yu, V.P.1
Koehler, M.2
Steinlein, C.3
-
20
-
-
0033106326
-
Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
-
Xu X, Weaver Z, Linke SP et al. Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Mol Cell 1999; 3(3): 389-395.
-
(1999)
Mol Cell
, vol.3
, Issue.3
, pp. 389-395
-
-
Xu, X.1
Weaver, Z.2
Linke, S.P.3
-
21
-
-
0037169354
-
Cancer susceptibility and the functions of BRCA1 and BRCA2
-
Venkitaraman AR. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 2002; 108(2): 171-182.
-
(2002)
Cell
, vol.108
, Issue.2
, pp. 171-182
-
-
Venkitaraman, A.R.1
-
22
-
-
0035093737
-
DNA double-strand breaks: signaling, repair and the cancer connection
-
Khanna KK, Jackson SP. DNA double-strand breaks: signaling, repair and the cancer connection. Nat Genet 2001; 27: 247-254.
-
(2001)
Nat Genet
, vol.27
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
23
-
-
0033213392
-
Brca1 controls homology-directed DNA repair
-
Moynahan ME, Chiu JW, Koller BH et al. Brca1 controls homology-directed DNA repair. Mol Cell 1999; 4(4): 511-518.
-
(1999)
Mol Cell
, vol.4
, Issue.4
, pp. 511-518
-
-
Moynahan, M.E.1
Chiu, J.W.2
Koller, B.H.3
-
24
-
-
0035099044
-
BRCA2 Is required for homology-directed repair of chromosomal breaks
-
Moynahan ME, Pierce AJ, Jasin M. BRCA2 Is required for homology-directed repair of chromosomal breaks. Mol Cell 2001; 7(2): 263-272.
-
(2001)
Mol Cell
, vol.7
, Issue.2
, pp. 263-272
-
-
Moynahan, M.E.1
Pierce, A.J.2
Jasin, M.3
-
25
-
-
0035801472
-
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
-
Tutt A, Bertwistle D, Valentine J et al. Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences. EMBO J 2001; 20(17): 4704-4716.
-
(2001)
EMBO J
, vol.20
, Issue.17
, pp. 4704-4716
-
-
Tutt, A.1
Bertwistle, D.2
Valentine, J.3
-
26
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Wang Y, Cortez D, Yazdi P et al. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 2000; 14: 927-939.
-
(2000)
Genes Dev
, vol.14
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
-
27
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull TT, Rogakou EP, Yamazaki V et al. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 2000; 10(15): 886-895.
-
(2000)
Curr Biol
, vol.10
, Issue.15
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
-
28
-
-
0034697973
-
BRCA1 Is associated with a human SWI/SNFrelated complex: linking chromatin remodeling to breast cancer
-
Bochar DA, Wang L, Beniya H et al. BRCA1 Is associated with a human SWI/SNFrelated complex: linking chromatin remodeling to breast cancer. Cell 2000; 102 (2): 257-265.
-
(2000)
Cell
, vol.102
, Issue.2
, pp. 257-265
-
-
Bochar, D.A.1
Wang, L.2
Beniya, H.3
-
29
-
-
0035842893
-
BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations
-
Ye Q, Hu YF, Zhong H et al. BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. J Cell Biol 2001; 155(6): 911-922.
-
(2001)
J Cell Biol
, vol.155
, Issue.6
, pp. 911-922
-
-
Ye, Q.1
Hu, Y.F.2
Zhong, H.3
-
30
-
-
0035942190
-
Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity
-
Ruffner H, Joazeiro CA, Hemmati D et al. Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity. Proc Natl Acad Sci USA 2001; 98(9): 5134-5139.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.9
, pp. 5134-5139
-
-
Ruffner, H.1
Joazeiro, C.A.2
Hemmati, D.3
-
31
-
-
0031466027
-
RAD51 Interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2
-
Wong AK, Pero R, Ormonde PA et al. RAD51 Interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2. J Biol Chem 1997; 272(51): 31941-31944.
-
(1997)
J Biol Chem
, vol.272
, Issue.51
, pp. 31941-31944
-
-
Wong, A.K.1
Pero, R.2
Ormonde, P.A.3
-
32
-
-
0034600109
-
Clinicopathologic features of BRCA-linked and sporadic ovarian cancer
-
Boyd J, Sonoda Y, Federici MG et al. Clinicopathologic features of BRCA-linked and sporadic ovarian cancer. JAMA 2000; 283(17): 2260-2265.
-
(2000)
JAMA
, vol.283
, Issue.17
, pp. 2260-2265
-
-
Boyd, J.1
Sonoda, Y.2
Federici, M.G.3
-
33
-
-
37849030476
-
Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer
-
Chetrit A, Hirsh-Yechezkel G, Ben-David Y et al. Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer. J Clin Oncol 2008; 26(1): 20-25.
-
(2008)
J Clin Oncol
, vol.26
, Issue.1
, pp. 20-25
-
-
Chetrit, A.1
Hirsh-Yechezkel, G.2
Ben-David, Y.3
-
34
-
-
57149093237
-
'BRCAness' syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations
-
Epub 2008 Oct 27
-
Tan DS, Rothermundt C, Thomas K et al. 'BRCAness' syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations. J Clin Oncol 2008; 26(34): 5530-5536. Epub 2008 Oct 27.
-
(2008)
J Clin Oncol
, vol.26
, Issue.34
, pp. 5530-5536
-
-
Tan, D.S.1
Rothermundt, C.2
Thomas, K.3
-
35
-
-
0037403380
-
Improved survival in women with BRCAassociated ovarian carcinoma
-
Cass I, Baldwin RL, Varkey T et al. Improved survival in women with BRCAassociated ovarian carcinoma. Cancer 2003; 97: 2187-2195.
-
(2003)
Cancer
, vol.97
, pp. 2187-2195
-
-
Cass, I.1
Baldwin, R.L.2
Varkey, T.3
-
36
-
-
80053950209
-
Association of BRCA1 and BRCA2 mutations with survival, chemo- therapy sensitivity, and gene mutator phenotype in patients with ovarian cancer
-
Yang D, Khan S, Sun Y et al. Association of BRCA1 and BRCA2 mutations with survival, chemo- therapy sensitivity, and gene mutator phenotype in patients with ovarian cancer. JAMA 2011; 306: 1557-1565.
-
(2011)
JAMA
, vol.306
, pp. 1557-1565
-
-
Yang, D.1
Khan, S.2
Sun, Y.3
-
38
-
-
0000102949
-
Poly(ADP-ribose) polymerase: a molecular nicksensor
-
de Murcia G, de Murcia JM. Poly(ADP-ribose) polymerase: a molecular nicksensor. Trends Biochem Sci 1994; 19(4): 172-176.
-
(1994)
Trends Biochem Sci
, vol.19
, Issue.4
, pp. 172-176
-
-
de Murcia, G.1
De Murcia, J.M.2
-
39
-
-
0033198919
-
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
-
D'Amours D, Desnoyers S, D'Silva I et al. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem J 1999; 342(2): 249-268.
-
(1999)
Biochem J
, vol.342
, Issue.2
, pp. 249-268
-
-
D'Amours, D.1
Desnoyers, S.2
D'Silva, I.3
-
40
-
-
2942703171
-
Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure
-
Poirier GG, de Murcia G, Jongstra-Bilen J et al. Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure. Proc Natl Acad Sci USA 1982; 79(11): 3423-3427.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, Issue.11
, pp. 3423-3427
-
-
Poirier, G.G.1
de Murcia, G.2
Jongstra-Bilen, J.3
-
41
-
-
0038583869
-
Spatial and temporal cellular responses to single-strand breaks in human cells
-
Okano S, Lan L, Caldecott KW et al. Spatial and temporal cellular responses to single-strand breaks in human cells. Mol Cell Biol 2003; 23(11): 3974-3981.
-
(2003)
Mol Cell Biol
, vol.23
, Issue.11
, pp. 3974-3981
-
-
Okano, S.1
Lan, L.2
Caldecott, K.W.3
-
42
-
-
0041378046
-
XRCC1 and DNA strand break repair
-
Caldecott KW. XRCC1 and DNA strand break repair. DNA Repair 2003; 2(9): 955-969.
-
(2003)
DNA Repair
, vol.2
, Issue.9
, pp. 955-969
-
-
Caldecott, K.W.1
-
43
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
Hoeijakers JHJ. Genome maintenance mechanisms for preventing cancer. Nature 2001; 411(6835): 366-374.
-
(2001)
Nature
, vol.411
, Issue.6835
, pp. 366-374
-
-
Hoeijakers, J.H.J.1
-
44
-
-
0032717347
-
Involvement of poly(ADP-ribose) polymerase in base excision repair
-
Dantzer F, Schreiber V, Niedergang C et al. Involvement of poly(ADP-ribose) polymerase in base excision repair. Biochimie 1999; 81(1-2): 69-75.
-
(1999)
Biochimie
, vol.81
, Issue.1-2
, pp. 69-75
-
-
Dantzer, F.1
Schreiber, V.2
Niedergang, C.3
-
45
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, McCabe N, Lord CJ et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005; 434(7035): 917-921.
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
-
46
-
-
0034720734
-
Base excision repair Is impaired in mammalian cells lacking poly(ADP-ribose) polymerase-1â
-
Dantzer F, de La Rubia G, Méissier-De Murcia J et al. Base excision repair Is impaired in mammalian cells lacking poly(ADP-ribose) polymerase-1â. Biochemistry 2000; 39(25): 7559-7569.
-
(2000)
Biochemistry
, vol.39
, Issue.25
, pp. 7559-7569
-
-
Dantzer, F.1
de La Rubia, G.2
Méissier-De Murcia, J.3
-
47
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
Bryant HE, Schultz N, Thomas HD et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 2005; 434(7035): 913-917.
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
-
48
-
-
0344875495
-
Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination
-
Schultz N, Lopez E, Saleh-Gohari N et al. Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination. Nucleic Acids Res 2003; 31: 4959-4964.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 4959-4964
-
-
Schultz, N.1
Lopez, E.2
Saleh-Gohari, N.3
-
49
-
-
2342524565
-
Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks
-
Yang YG, Cortes U, Patnaik S et al. Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks. Oncogene 2004; 23: 3872-3882.
-
(2004)
Oncogene
, vol.23
, pp. 3872-3882
-
-
Yang, Y.G.1
Cortes, U.2
Patnaik, S.3
-
50
-
-
0019151522
-
ADP-ribosylation of nuclear proteins in normal lymphocytes and in low-grade malignant non-Hodgkin lymphoma cells
-
Wielckens K, Garbrecht M, Kittler M et al. ADP-ribosylation of nuclear proteins in normal lymphocytes and in low-grade malignant non-Hodgkin lymphoma cells. Eur J Biochem 1980; 104(1): 279-287.
-
(1980)
Eur J Biochem
, vol.104
, Issue.1
, pp. 279-287
-
-
Wielckens, K.1
Garbrecht, M.2
Kittler, M.3
-
51
-
-
0020621890
-
Aberration of poly(adenosine diphosphate-ribose) metabolism in human colon adenomatous polyps and cancers
-
Hirai K, Ueda K, Hayaishi O. Aberration of poly(adenosine diphosphate-ribose) metabolism in human colon adenomatous polyps and cancers. Cancer Res 1983; 43(7): 3441-3446.
-
(1983)
Cancer Res
, vol.43
, Issue.7
, pp. 3441-3446
-
-
Hirai, K.1
Ueda, K.2
Hayaishi, O.3
-
52
-
-
0025770287
-
Enhanced expression of poly(ADP-ribose) synthetase gene in malignant lymphoma
-
Tomoda T, Kurashige T, Moriki T et al. Enhanced expression of poly(ADP-ribose) synthetase gene in malignant lymphoma. Am J Hematol 1991; 37(4): 223-227.
-
(1991)
Am J Hematol
, vol.37
, Issue.4
, pp. 223-227
-
-
Tomoda, T.1
Kurashige, T.2
Moriki, T.3
-
53
-
-
0035029463
-
Enhanced polyadenosinediphosphateribosylation in cirrhotic liver and carcinoma tissues in patients with hepatocellular carcinoma
-
Shiobara M, Miyazaki M, Ito H et al. Enhanced polyadenosinediphosphateribosylation in cirrhotic liver and carcinoma tissues in patients with hepatocellular carcinoma. J Gastroenterol Hepatol 2001; 16(3): 338-344.
-
(2001)
J Gastroenterol Hepatol
, vol.16
, Issue.3
, pp. 338-344
-
-
Shiobara, M.1
Miyazaki, M.2
Ito, H.3
-
54
-
-
0031848832
-
Involvement of the mismatch repair system in temozolomide-induced apoptosis
-
D'Atri S, Tenori L, Lacal PM et al. Involvement of the mismatch repair system in temozolomide-induced apoptosis. Mol Pharmacol 1998; 54(2): 334-341.
-
(1998)
Mol Pharmacol
, vol.54
, Issue.2
, pp. 334-341
-
-
D'Atri, S.1
Tenori, L.2
Lacal, P.M.3
-
55
-
-
20944447651
-
Temozolomide pharmacodynamics in patients with metastatic melanoma: DNA damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1
-
Plummer ER, Middleton MR, Jones C et al. Temozolomide pharmacodynamics in patients with metastatic melanoma: DNA damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1. Clin Cancer Res 2005; 11(9): 3402-3409.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.9
, pp. 3402-3409
-
-
Plummer, E.R.1
Middleton, M.R.2
Jones, C.3
-
56
-
-
10744233628
-
Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repairdeficient cells
-
Curtin NJ, Wang LZ, Yiakouvaki A et al. Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repairdeficient cells. Clin Cancer Res 2004; 10(3): 881-889.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.3
, pp. 881-889
-
-
Curtin, N.J.1
Wang, L.Z.2
Yiakouvaki, A.3
-
57
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
Epub 2009 Jun 24
-
Fong PC, Boss DS, Yap TA et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009; 361(2): 123-134. Epub 2009 Jun 24.
-
(2009)
N Engl J Med
, vol.361
, Issue.2
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
-
58
-
-
77954032829
-
Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
-
Fong PC, Yap TA, Boss DS et al. Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. J Clin Oncol 2010; 28: 2512-2519.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2512-2519
-
-
Fong, P.C.1
Yap, T.A.2
Boss, D.S.3
-
59
-
-
77955039099
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
-
Audeh MW, Carmichael J, Penson RT et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet 2010; 376: 245-251.
-
(2010)
Lancet
, vol.376
, pp. 245-251
-
-
Audeh, M.W.1
Carmichael, J.2
Penson, R.T.3
-
60
-
-
80052389761
-
Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study
-
Gelmon KA, Tischkowitz M, Mackay H et al. Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study. Lancet 2011; 12: 852-861.
-
(2011)
Lancet
, vol.12
, pp. 852-861
-
-
Gelmon, K.A.1
Tischkowitz, M.2
Mackay, H.3
-
61
-
-
80053135643
-
Phase II randomized placebocontrolled study of olaparib (AZD2281) in patients with platinum-sensitive relapsed serous ovarian cancer (PSR SOC)
-
Ledermann JA, Harter P, Gourley C et al. Phase II randomized placebocontrolled study of olaparib (AZD2281) in patients with platinum-sensitive relapsed serous ovarian cancer (PSR SOC). J Clin Oncol 2011; 29(suppl): abstract 5003.
-
(2011)
J Clin Oncol
, vol.29
, pp. 5003
-
-
Ledermann, J.A.1
Harter, P.2
Gourley, C.3
-
62
-
-
79551577398
-
Phase I.I study of the oral P.A.R.P inhibitor olaparib (A.Z.D2281) versus liposomal doxorubicin in ovarian cancer patients with B.R.C.A1 and/or BRCA2 mutations
-
Oct 8-12.2010. Milan.Italy. Abstract
-
Kaye S, Kaufman B, Lubinski J et al. Phase II study of the oral PARP inhibitor olaparib (AZD2281) versus liposomal doxorubicin in ovarian cancer patients with BRCA1 and/or BRCA2 mutations. European Society for Medical Oncology (ESMO) Congress. 2010; Oct 8-12, 2010. Milan, Italy. Abstract 3725.
-
(2010)
European Society for Medical Oncology (ESMO) Congress
, pp. 3725
-
-
Kaye, S.1
Kaufman, B.2
Lubinski, J.3
-
63
-
-
77956336578
-
Pharmacodynamic response in phaseI combination study of ABT-888 and topotecan in adults with refractory solid tumors andlymphomas
-
Ji JJ, Kummar S, Chen AP et al. Pharmacodynamic response in phaseI combination study of ABT-888 and topotecan in adults with refractory solid tumors andlymphomas. J ClinOncol 2010; 28(suppl 15s): abstract 2514.
-
(2010)
J ClinOncol
, vol.28
, Issue.15 SUPPL.
, pp. 2514
-
-
Ji, J.J.1
Kummar, S.2
Chen, A.P.3
-
64
-
-
84856009743
-
Phase I study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the poly(ADP-ribose) polymerase (PARP) inhibitor veliparib (ABT-888; V) in combination with irinotecan (CPT-11; Ir) in patients (pts) with advanced solid tumors
-
Lorusso P, Ji JJ, Li J et al. Phase I study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the poly(ADP-ribose) polymerase (PARP) inhibitor veliparib (ABT-888; V) in combination with irinotecan (CPT-11; Ir) in patients (pts) with advanced solid tumors. J Clin Oncol 2011; 29(suppl): abstract 3000.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3000
-
-
Lorusso, P.1
Ji, J.J.2
Li, J.3
-
65
-
-
33748639077
-
Differential DNA methylation profiles in gynaecological cancers and correlation with clinico-pathological data
-
Yang HJ, Liu VWS, Wang Y et al. Differential DNA methylation profiles in gynaecological cancers and correlation with clinico-pathological data. BMC Cancer 2006; 6: 212.
-
(2006)
BMC Cancer
, vol.6
, pp. 212
-
-
Yang, H.J.1
Liu, V.W.S.2
Wang, Y.3
-
66
-
-
39549091276
-
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities
-
Press JZ, De Luca A, Boyd N et al. Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities. BMC Cancer 2008; 8: 17-24.
-
(2008)
BMC Cancer
, vol.8
, pp. 17-24
-
-
Press, J.Z.1
De Luca, A.2
Boyd, N.3
-
67
-
-
0038075462
-
Disruption of the Fanconi anemia- BRCA pathway in cisplatin-sensitive ovarian tumors
-
Taniguchi T, Tischkowitz M, Ameziane N et al. Disruption of the Fanconi anemia- BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 2003; 9(5): 568-574.
-
(2003)
Nat Med
, vol.9
, Issue.5
, pp. 568-574
-
-
Taniguchi, T.1
Tischkowitz, M.2
Ameziane, N.3
-
68
-
-
10744233204
-
EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer
-
Hughes-Davies L, Huntsman D, Ruas M et al. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell 2003; 115(5): 523-535.
-
(2003)
Cell
, vol.115
, Issue.5
, pp. 523-535
-
-
Hughes-Davies, L.1
Huntsman, D.2
Ruas, M.3
-
69
-
-
30444457408
-
Amplification of EMSY, a novel oncogene on 11q13, in high grade ovarian surface epithelial carcinomas
-
Brown LA, Irving J, Parker R et al. Amplification of EMSY, a novel oncogene on 11q13, in high grade ovarian surface epithelial carcinomas. Gynecol Oncol 2006; 100: 264-270.
-
(2006)
Gynecol Oncol
, vol.100
, pp. 264-270
-
-
Brown, L.A.1
Irving, J.2
Parker, R.3
-
70
-
-
10744233204
-
EMSY Links the BRCA2 pathway to sporadic breast and ovarian cancer
-
Hughes-Davies L, Huntsman D, Ruas M et al. EMSY Links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell 2003; 115: 523-535.
-
(2003)
Cell
, vol.115
, pp. 523-535
-
-
Hughes-Davies, L.1
Huntsman, D.2
Ruas, M.3
-
71
-
-
79957516181
-
EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/ recombination syndromes as checkpoint diseases
-
Cousineau I, Belmaaza A. EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/ recombination syndromes as checkpoint diseases. Mol Genet Genomics 2011; 285: 325-340.
-
(2011)
Mol Genet Genomics
, vol.285
, pp. 325-340
-
-
Cousineau, I.1
Belmaaza, A.2
-
72
-
-
2342596529
-
The Fanconi anemia/BRCA signaling pathway: disruption in cisplatin-sensitive ovarian cancers
-
D'Andrea AD. The Fanconi anemia/BRCA signaling pathway: disruption in cisplatin-sensitive ovarian cancers. Cell Cycle 2003; 2: 290-292.
-
(2003)
Cell Cycle
, vol.2
, pp. 290-292
-
-
D'Andrea, A.D.1
-
73
-
-
33845999615
-
Essential role for nuclear PTEN in maintaining chromosomal integrity
-
Shen WH, Balajee AS, Wang J et al. Essential role for nuclear PTEN in maintaining chromosomal integrity. Cell 2007; 128: 157-170.
-
(2007)
Cell
, vol.128
, pp. 157-170
-
-
Shen, W.H.1
Balajee, A.S.2
Wang, J.3
-
74
-
-
77955439715
-
Detection of inherited mutations for breast and ovarian cancer using genomic capture and massively parallel sequencing
-
Walsh T, Lee MK, Casadei S et al. Detection of inherited mutations for breast and ovarian cancer using genomic capture and massively parallel sequencing. PNAS 2010; 107: 12629-12633.
-
(2010)
PNAS
, vol.107
, pp. 12629-12633
-
-
Walsh, T.1
Lee, M.K.2
Casadei, S.3
-
75
-
-
81055126264
-
Mutations in 12 genes for inherited ovarian, fallopian tune, and peritoneal carcinoma identified by massive parallel sequencing
-
Walsh T, Casadei S, Lee M et al. Mutations in 12 genes for inherited ovarian, fallopian tune, and peritoneal carcinoma identified by massive parallel sequencing. PNAS 2011; 108: 18032-18037.
-
(2011)
PNAS
, vol.108
, pp. 18032-18037
-
-
Walsh, T.1
Casadei, S.2
Lee, M.3
-
76
-
-
79959838081
-
Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma
-
Bell D, Berchuck A, Birrer M et al. Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature 2011; 474: 609-615.
-
(2011)
Nature
, vol.474
, pp. 609-615
-
-
Bell, D.1
Berchuck, A.2
Birrer, M.3
|