Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism

Molecular Pharmacology

Volumn 84, Issue 5, 2013, Pages 774-786

  Slosky, Lauren M ^a   Thompson, Brandon J ^a   Sanchez Covarrubias, Lucy ^a   Zhang, Yifeng ^a   Laracuente, Mei Li ^a   Vanderah, Todd W ^a   Ronaldson, Patrick T ^a   Davis, Thomas P ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CONSTITUTIVE ANDROSTANE RECEPTOR; DACTINOMYCIN; DEOXYRIBODIPYRIMIDINE PHOTOLYASE; GLYCOPROTEIN P INHIBITOR; HOT WATER; MORPHINE; MULTIDRUG RESISTANCE PROTEIN; OKADAIC ACID; OPIATE; PARACETAMOL; VERAPAMIL;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; IN VIVO STUDY; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TAIL FLICK TEST;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; FEMALE; MORPHINE; P-GLYCOPROTEIN; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 84886034239     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.113.086298     Document Type: Article

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