메뉴 건너뛰기




Volumn 41, Issue 19, 2013, Pages 8926-8942

A common docking domain in progesterone receptor-B links DUSP6 and CK2 signaling to proliferative transcriptional programs in breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE II; DUAL SPECIFICITY PHOSPHATASE 6; GESTAGEN; JANUS KINASE; PROGESTERONE RECEPTOR B; STAT PROTEIN; STAT5 PROTEIN; WNT1 PROTEIN;

EID: 84885961937     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt706     Document Type: Article
Times cited : (40)

References (97)
  • 1
    • 0027723268 scopus 로고
    • Cloning of the rat progesterone receptor gene 5′-region and identification of two functionally distinct promoters
    • Kraus, W.L., Montano, M.M. and Katzenellenbogen, B.S. (1993) Cloning of the rat progesterone receptor gene 5′-region and identification of two functionally distinct promoters. Mol. Endocrinol., 7, 1603-1616.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 1603-1616
    • Kraus, W.L.1    Montano, M.M.2    Katzenellenbogen, B.S.3
  • 2
    • 0025239785 scopus 로고
    • Two distinct estrogenregulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
    • Kastner, P., Krust, A., Turcotte, B., Stropp, U., Tora, L., Gronemeyer, H. and Chambon, P. (1990) Two distinct estrogenregulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J., 9, 1603-1614.
    • (1990) EMBO J. , vol.9 , pp. 1603-1614
    • Kastner, P.1    Krust, A.2    Turcotte, B.3    Stropp, U.4    Tora, L.5    Gronemeyer, H.6    Chambon, P.7
  • 3
    • 0025239785 scopus 로고
    • Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
    • Kastner, P., Krust, A., Turcotte, B., Stropp, U., Tora, L., Gronemeyer, H. and Chambon, P. (1990) Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J., 9, 1603-1614.
    • (1990) EMBO J. , vol.9 , pp. 1603-1614
    • Kastner, P.1    Krust, A.2    Turcotte, B.3    Stropp, U.4    Tora, L.5    Gronemeyer, H.6    Chambon, P.7
  • 4
    • 82655172410 scopus 로고    scopus 로고
    • Structural and functional analysis of domains of the progesterone receptor
    • Hill, K.K., Roemer, S.C., Churchill, M.E. and Edwards, D.P. (2012) Structural and functional analysis of domains of the progesterone receptor. Mol. Cell. Endocrinol., 348, 418-429.
    • (2012) Mol. Cell. Endocrinol. , vol.348 , pp. 418-429
    • Hill, K.K.1    Roemer, S.C.2    Churchill, M.E.3    Edwards, D.P.4
  • 5
    • 0028073682 scopus 로고
    • A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform
    • Sartorius, C.A., Melville, M.Y., Hovland, A.R., Tung, L., Takimoto, G.S. and Horwitz, K.B. (1994) A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform. Mol. Endocrinol., 8, 1347-1360.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1347-1360
    • Sartorius, C.A.1    Melville, M.Y.2    Hovland, A.R.3    Tung, L.4    Takimoto, G.S.5    Horwitz, K.B.6
  • 6
    • 0032562712 scopus 로고    scopus 로고
    • Progesterone regulates transcription of the p21(WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300
    • Owen, G.I., Richer, J.K., Tung, L., Takimoto, G. and Horwitz, K.B. (1998) Progesterone regulates transcription of the p21(WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300. J. Biol Chem, 273, 10696-10701.
    • (1998) J. Biol Chem , vol.273 , pp. 10696-10701
    • Owen, G.I.1    Richer, J.K.2    Tung, L.3    Takimoto, G.4    Horwitz, K.B.5
  • 7
    • 0033047771 scopus 로고    scopus 로고
    • Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family
    • Stoecklin, E., Wissler, M., Schaetzle, D., Pfitzner, E. and Groner, B. (1999) Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family. J. Steroid Biochem. Mol. Biol., 69, 195-204.
    • (1999) J. Steroid Biochem. Mol. Biol. , vol.69 , pp. 195-204
    • Stoecklin, E.1    Wissler, M.2    Schaetzle, D.3    Pfitzner, E.4    Groner, B.5
  • 8
    • 3543002856 scopus 로고    scopus 로고
    • Estrogens and progesterone promote persistent CCND1 gene activation during G1 by inducing transcriptional derepression via c-Jun/c-Fos/estrogen receptor (progesterone receptor) complex assembly to a distal regulatory element and recruitment of cyclin D1 to its own gene promoter
    • Cicatiello, L., Addeo, R., Sasso, A., Altucci, L., Petrizzi, V.B., Borgo, R., Cancemi, M., Caporali, S., Caristi, S., Scafoglio, C. et al. (2004) Estrogens and progesterone promote persistent CCND1 gene activation during G1 by inducing transcriptional derepression via c-Jun/c-Fos/estrogen receptor (progesterone receptor) complex assembly to a distal regulatory element and recruitment of cyclin D1 to its own gene promoter. Mol. Cell. Biol., 24, 7260-7274.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7260-7274
    • Cicatiello, L.1    Addeo, R.2    Sasso, A.3    Altucci, L.4    Petrizzi, V.B.5    Borgo, R.6    Cancemi, M.7    Caporali, S.8    Caristi, S.9    Scafoglio, C.10
  • 9
    • 0033305547 scopus 로고    scopus 로고
    • Nuclear receptor coregulators: Cellular and molecular biology
    • McKenna, N.J., Lanz, R.B. and O'Malley, B.W. (1999) Nuclear receptor coregulators: cellular and molecular biology. Endocrine Rev., 20, 321-344.
    • (1999) Endocrine Rev. , vol.20 , pp. 321-344
    • McKenna, N.J.1    Lanz, R.B.2    O'Malley, B.W.3
  • 10
    • 36849096094 scopus 로고    scopus 로고
    • Phosphorylation dependent antagonism of sumoylation de-represses progesterone receptor action in breast cancer cells
    • Daniel, A.R., Faivre, E.J. and Lange, C.A. (2007) phosphorylation dependent antagonism of sumoylation de-represses progesterone receptor action in breast cancer cells. Mol. Endocrinol., 21, 2890-2906.
    • (2007) Mol. Endocrinol. , vol.21 , pp. 2890-2906
    • Daniel, A.R.1    Faivre, E.J.2    Lange, C.A.3
  • 11
    • 0033967491 scopus 로고    scopus 로고
    • Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome
    • Lange, C.A., Shen, T. and Horwitz, K.B. (2000) Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome. Proc. Natl Acad. Sci. USA, 97, 1032-1037.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 1032-1037
    • Lange, C.A.1    Shen, T.2    Horwitz, K.B.3
  • 13
    • 84863572365 scopus 로고    scopus 로고
    • Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression
    • Knutson, T.P., Daniel, A.R., Fan, D., Silverstein, K.A., Covington, K.R., Fuqua, S.A. and Lange, C.A. (2012) Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression. Breast Cancer Res., 14, R95.
    • (2012) Breast Cancer Res. , vol.14
    • Knutson, T.P.1    Daniel, A.R.2    Fan, D.3    Silverstein, K.A.4    Covington, K.R.5    Fuqua, S.A.6    Lange, C.A.7
  • 14
    • 78049332125 scopus 로고    scopus 로고
    • The progesterone receptor hinge region regulates the kinetics of transcriptional responses through acetylation, phosphorylation, and nuclear retention
    • Daniel, A.R., Gaviglio, A.L., Czaplicki, L.M., Hillard, C.J., Housa, D. and Lange, C.A. (2011) The progesterone receptor hinge region regulates the kinetics of transcriptional responses through acetylation, phosphorylation, and nuclear retention. Mol. Endocrinol., 24, 2126-2138.
    • (2011) Mol. Endocrinol. , vol.24 , pp. 2126-2138
    • Daniel, A.R.1    Gaviglio, A.L.2    Czaplicki, L.M.3    Hillard, C.J.4    Housa, D.5    Lange, C.A.6
  • 15
    • 10044257416 scopus 로고    scopus 로고
    • Phosphorylation of progesterone receptor serine 400 mediates ligandindependent transcriptional activity in response to activatoin of cyclin-dependent protein kinase2
    • Pierson-Mullany, L.K. and Lange, C.A. (2004) Phosphorylation of progesterone receptor serine 400 mediates ligandindependent transcriptional activity in response to activatoin of cyclin-dependent protein kinase2. Mol. Cell. Biol., 24, 10542-10557.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 10542-10557
    • Pierson-Mullany, L.K.1    Lange, C.A.2
  • 16
    • 0037334895 scopus 로고    scopus 로고
    • One-thousand-and-one substrates of protein kinase CK2?
    • Meggio, F. and Pinna, L.A. (2003) One-thousand-and-one substrates of protein kinase CK2? FASEB J., 17, 349-368.
    • (2003) FASEB J. , vol.17 , pp. 349-368
    • Meggio, F.1    Pinna, L.A.2
  • 18
    • 0027988153 scopus 로고
    • Identification of phosphorylation sites unique to the B form of human progesterone receptor. In vitro phosphorylation by casein kinase II
    • Zhang, Y., Beck, C.A., Poletti, A., Edwards, D.P. and Weigel, N.L. (1994) Identification of phosphorylation sites unique to the B form of human progesterone receptor. In vitro phosphorylation by casein kinase II. J. Biol. Chem., 269, 31034-31040.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31034-31040
    • Zhang, Y.1    Beck, C.A.2    Poletti, A.3    Edwards, D.P.4    Weigel, N.L.5
  • 19
    • 79956122926 scopus 로고    scopus 로고
    • Ck2-dependent phosphorylation of progesterone receptors (PR) on Ser81 regulates pr-β isoform-specific target gene expression in breast cancer cells
    • Hagan, C.R., Regan, T.M., Dressing, G.E. and Lange, C.A. (2011) ck2-dependent phosphorylation of progesterone receptors (PR) on Ser81 regulates pr-β isoform-specific target gene expression in breast cancer cells. Mol. Cell. Biol, 31, 2439-2452.
    • (2011) Mol. Cell. Biol , vol.31 , pp. 2439-2452
    • Hagan, C.R.1    Regan, T.M.2    Dressing, G.E.3    Lange, C.A.4
  • 20
    • 53249090648 scopus 로고    scopus 로고
    • Protein kinase CK2 in human diseases
    • Guerra, B. and Issinger, O.G. (2008) Protein kinase CK2 in human diseases. Curr. Med. Chem., 15, 1870-1886.
    • (2008) Curr. Med. Chem. , vol.15 , pp. 1870-1886
    • Guerra, B.1    Issinger, O.G.2
  • 21
    • 63749084159 scopus 로고    scopus 로고
    • Scaffolding actions of membrane-associated progesterone receptors
    • Hagan, C.R., Faivre, E.J. and Lange, C.A. (2009) Scaffolding actions of membrane-associated progesterone receptors. Steroids, 74, 568-572.
    • (2009) Steroids , vol.74 , pp. 568-572
    • Hagan, C.R.1    Faivre, E.J.2    Lange, C.A.3
  • 22
    • 0037371863 scopus 로고    scopus 로고
    • Two domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cells
    • Ballare, C., Uhrig, M., Bechtold, T., Sancho, E., Di Domenico, M., Migliaccio, A., Auricchio, F. and Beato, M. (2003) Two domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cells. Mol. Cell. Biol., 23, 1994-2008.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 1994-2008
    • Ballare, C.1    Uhrig, M.2    Bechtold, T.3    Sancho, E.4    Di Domenico, M.5    Migliaccio, A.6    Auricchio, F.7    Beato, M.8
  • 23
    • 0034852802 scopus 로고    scopus 로고
    • Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases
    • Boonyaratanakornkit, V., Scott, M.P., Ribon, V., Sherman, L., Anderson, S.M., Maller, J.L., Miller, W.T. and Edwards, D.P. (2001) Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases. Mol. Cell, 8, 269-280.
    • (2001) Mol. Cell , vol.8 , pp. 269-280
    • Boonyaratanakornkit, V.1    Scott, M.P.2    Ribon, V.3    Sherman, L.4    Anderson, S.M.5    Maller, J.L.6    Miller, W.T.7    Edwards, D.P.8
  • 25
    • 0032553553 scopus 로고    scopus 로고
    • Convergence of progesterone with growth factor and cytokine signaling in breast cancer. Progesterone receptors regulate signal transducers and activators of transcription expression and activity
    • Richer, J.K., Lange, C.A., Manning, N.G., Owen, G., Powell, R. and Horwitz, K.B. (1998) Convergence of progesterone with growth factor and cytokine signaling in breast cancer. Progesterone receptors regulate signal transducers and activators of transcription expression and activity. J. Biol. Chem., 273, 31317-31326.
    • (1998) J. Biol. Chem. , vol.273 , pp. 31317-31326
    • Richer, J.K.1    Lange, C.A.2    Manning, N.G.3    Owen, G.4    Powell, R.5    Horwitz, K.B.6
  • 26
    • 0036311098 scopus 로고    scopus 로고
    • Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator
    • Wardell, S.E., Boonyaratanakornkit, V., Adelman, J.S., Aronheim, A. and Edwards, D.P. (2002) Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator. Mol Cell Biol, 22, 5451-5466.
    • (2002) Mol Cell Biol , vol.22 , pp. 5451-5466
    • Wardell, S.E.1    Boonyaratanakornkit, V.2    Adelman, J.S.3    Aronheim, A.4    Edwards, D.P.5
  • 27
    • 0033788484 scopus 로고    scopus 로고
    • A conserved docking motif in MAP kinases common to substrates, activators and regulators
    • Tanoue, T., Adachi, M., Moriguchi, T. and Nishida, E. (2000) A conserved docking motif in MAP kinases common to substrates, activators and regulators. Nat. Cell Biol., 2, 110-116.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 110-116
    • Tanoue, T.1    Adachi, M.2    Moriguchi, T.3    Nishida, E.4
  • 28
    • 0035990913 scopus 로고    scopus 로고
    • Docking interactions in the mitogen-activated protein kinase cascades
    • Tanoue, T. and Nishida, E. (2002) Docking interactions in the mitogen-activated protein kinase cascades. Pharmacol. Ther., 93, 193-202.
    • (2002) Pharmacol. Ther. , vol.93 , pp. 193-202
    • Tanoue, T.1    Nishida, E.2
  • 29
    • 0034759115 scopus 로고    scopus 로고
    • Regulation of MAP kinases by docking domains
    • Enslen, H. and Davis, R.J. (2001) Regulation of MAP kinases by docking domains. Biol. Cell, 93, 5-14.
    • (2001) Biol. Cell , vol.93 , pp. 5-14
    • Enslen, H.1    Davis, R.J.2
  • 30
    • 0042018741 scopus 로고    scopus 로고
    • Breast cancer and hormone-replacement therapy in the Million Women study
    • Beral, V. (2003) Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet, 362, 419-427.
    • (2003) Lancet , vol.362 , pp. 419-427
    • Beral, V.1
  • 31
    • 1842867053 scopus 로고    scopus 로고
    • Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: The women's health initiative randomized controlled trial
    • Anderson, G.L., Limacher, M., Assaf, A.R., Bassford, T., Beresford, S.A., Black, H., Bonds, D., Brunner, R., Brzyski, R., Caan, B. et al. (2004) Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA, 291, 1701-1712.
    • (2004) JAMA , vol.291 , pp. 1701-1712
    • Anderson, G.L.1    Limacher, M.2    Assaf, A.R.3    Bassford, T.4    Beresford, S.A.5    Black, H.6    Bonds, D.7    Brunner, R.8    Brzyski, R.9    Caan, B.10
  • 32
    • 1342325380 scopus 로고    scopus 로고
    • Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer
    • Gregory, C.W., Fei, X., Ponguta, L.A., He, B., Bill, H.M., French, F.S. and Wilson, E.M. (2004) Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer. J. Biol. Chem., 279, 7119-7130.
    • (2004) J. Biol. Chem. , vol.279 , pp. 7119-7130
    • Gregory, C.W.1    Fei, X.2    Ponguta, L.A.3    He, B.4    Bill, H.M.5    French, F.S.6    Wilson, E.M.7
  • 33
    • 33751028441 scopus 로고    scopus 로고
    • Activated c-SRC in ductal carcinoma in situ correlates with high tumour grade, high proliferation and HER2 positivity
    • Wilson, G.R., Cramer, A., Welman, A., Knox, F., Swindell, R., Kawakatsu, H., Clarke, R.B., Dive, C. and Bundred, N.J. (2006) Activated c-SRC in ductal carcinoma in situ correlates with high tumour grade, high proliferation and HER2 positivity. Br. J. Cancer, 95, 1410-1414.
    • (2006) Br. J. Cancer , vol.95 , pp. 1410-1414
    • Wilson, G.R.1    Cramer, A.2    Welman, A.3    Knox, F.4    Swindell, R.5    Kawakatsu, H.6    Clarke, R.B.7    Dive, C.8    Bundred, N.J.9
  • 35
    • 0020026749 scopus 로고
    • Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance
    • Horwitz, K.B., Mockus, M.B. and Lessey, B.A. (1982) Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance. Cell, 28, 633-642.
    • (1982) Cell , vol.28 , pp. 633-642
    • Horwitz, K.B.1    Mockus, M.B.2    Lessey, B.A.3
  • 36
    • 0028026693 scopus 로고
    • New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors; Only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP
    • Sartorius, C.A., Groshong, S.D., Miller, A., Powell, R.L., Tung, L., Takimoto, G. and Horwitz, K. (1994) New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors; only antiprogestin- occupied B-receptors are switched to transcriptional agonists by cAMP. Cancer Res., 54, 3868-3877.
    • (1994) Cancer Res. , vol.54 , pp. 3868-3877
    • Sartorius, C.A.1    Groshong, S.D.2    Miller, A.3    Powell, R.L.4    Tung, L.5    Takimoto, G.6    Horwitz, K.7
  • 38
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y. and Hochberg, Y. (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B., 57, 289-300.
    • (1995) J. R. Stat. Soc. Ser. B. , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 41
    • 33846138978 scopus 로고    scopus 로고
    • Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells
    • Faivre, E.J. and Lange, C.A. (2007) Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells. Mol. Cell. Biol., 27, 466-480.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 466-480
    • Faivre, E.J.1    Lange, C.A.2
  • 42
    • 41649119043 scopus 로고    scopus 로고
    • Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors
    • Faivre, E.J., Daniel, A.R., Hillard, C.J. and Lange, C.A. (2008) Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors. Mol. Endocrinol., 22, 823-837.
    • (2008) Mol. Endocrinol. , vol.22 , pp. 823-837
    • Faivre, E.J.1    Daniel, A.R.2    Hillard, C.J.3    Lange, C.A.4
  • 43
    • 0035254671 scopus 로고    scopus 로고
    • Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions
    • Tanoue, T., Maeda, R., Adachi, M. and Nishida, E. (2001) Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions. EMBO J., 20, 466-479.
    • (2001) EMBO J. , vol.20 , pp. 466-479
    • Tanoue, T.1    Maeda, R.2    Adachi, M.3    Nishida, E.4
  • 45
    • 0026051580 scopus 로고
    • Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes
    • Musgrove, E.A., Lee, C.S. and Sutherland, R.L. (1991) Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes. Mol. Cell. Biol., 11, 5032-5043.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5032-5043
    • Musgrove, E.A.1    Lee, C.S.2    Sutherland, R.L.3
  • 46
    • 13544276888 scopus 로고    scopus 로고
    • Progesterone receptors induce cell cycle progression via activation of mitogen activated protein kinases
    • Skildum, A., Faivre, E. and Lange, C.A. (2005) Progesterone receptors induce cell cycle progression via activation of mitogen activated protein kinases. Mol. Endocrinol., 19, 327-339.
    • (2005) Mol. Endocrinol. , vol.19 , pp. 327-339
    • Skildum, A.1    Faivre, E.2    Lange, C.A.3
  • 48
    • 0018175970 scopus 로고
    • Estrogen control of progesterone receptor in human breast cancer: Role of estradiol and antiestrogen
    • Horwitz, K.B., Koseki, Y. and McGuire, W.L. (1978) Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen. Endocrinology, 103, 1742-1751.
    • (1978) Endocrinology , vol.103 , pp. 1742-1751
    • Horwitz, K.B.1    Koseki, Y.2    McGuire, W.L.3
  • 49
    • 0028026693 scopus 로고
    • New T47D breast cancer cell lines for the independent study of progesterone B- and Areceptors: Only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP
    • Sartorius, C.A., Groshong, S.D., Miller, L.A., Powell, R.L., Tung, L., Takimoto, G.S. and Horwitz, K.B. (1994) New T47D breast cancer cell lines for the independent study of progesterone B- and Areceptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP. Cancer Res., 54, 3868-3877.
    • (1994) Cancer Res. , vol.54 , pp. 3868-3877
    • Sartorius, C.A.1    Groshong, S.D.2    Miller, L.A.3    Powell, R.L.4    Tung, L.5    Takimoto, G.S.6    Horwitz, K.B.7
  • 50
    • 84860339746 scopus 로고    scopus 로고
    • Role of phosphorylation in progesterone receptor signaling and specificity
    • Hagan, C.R., Daniel, A.R., Dressing, G.E. and Lange, C.A. (2012) Role of phosphorylation in progesterone receptor signaling and specificity. Mol. Cell. Endocrinol., 357, 43-49.
    • (2012) Mol. Cell. Endocrinol. , vol.357 , pp. 43-49
    • Hagan, C.R.1    Daniel, A.R.2    Dressing, G.E.3    Lange, C.A.4
  • 51
    • 79956071496 scopus 로고    scopus 로고
    • Progesterone receptor action: Defining a role in breast cancer
    • Daniel, A.R., Hagan, C.R. and Lange, C.A. (2011) Progesterone receptor action: defining a role in breast cancer. Expert Rev. Endocrinol. Metab., 6, 359-369.
    • (2011) Expert Rev. Endocrinol. Metab. , vol.6 , pp. 359-369
    • Daniel, A.R.1    Hagan, C.R.2    Lange, C.A.3
  • 52
    • 67349168694 scopus 로고    scopus 로고
    • Signaling inputs to progesterone receptor gene regulation and promoter selectivity
    • Daniel, A.R., Knutson, T.P. and Lange, C.A. (2009) Signaling inputs to progesterone receptor gene regulation and promoter selectivity. Mol. Cell. Endocrinol., 308, 47-52.
    • (2009) Mol. Cell. Endocrinol. , vol.308 , pp. 47-52
    • Daniel, A.R.1    Knutson, T.P.2    Lange, C.A.3
  • 53
    • 84860339746 scopus 로고    scopus 로고
    • Role of phosphorylation in progesterone receptor signaling and specificity
    • Hagan, C.R., Daniel, A.R., Dressing, G.E. and Lange, C.A. (2012) Role of phosphorylation in progesterone receptor signaling and specificity. Mol. Cell. Endocrinol., 357, 43-49.
    • (2012) Mol. Cell. Endocrinol. , vol.357 , pp. 43-49
    • Hagan, C.R.1    Daniel, A.R.2    Dressing, G.E.3    Lange, C.A.4
  • 54
    • 7244254418 scopus 로고    scopus 로고
    • MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2alpha
    • Castelli, M., Camps, M., Gillieron, C., Leroy, D., Arkinstall, S., Rommel, C. and Nichols, A. (2004) MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2alpha. J. Biol. Chem., 279, 44731-44739.
    • (2004) J. Biol. Chem. , vol.279 , pp. 44731-44739
    • Castelli, M.1    Camps, M.2    Gillieron, C.3    Leroy, D.4    Arkinstall, S.5    Rommel, C.6    Nichols, A.7
  • 56
    • 14044277677 scopus 로고    scopus 로고
    • Reversible oxidation of ERK-directed protein phosphatases drives oxidative toxicity in neurons
    • Levinthal, D.J. and Defranco, D.B. (2005) Reversible oxidation of ERK-directed protein phosphatases drives oxidative toxicity in neurons. J. Biol. Chem., 280, 5875-5883.
    • (2005) J. Biol. Chem. , vol.280 , pp. 5875-5883
    • Levinthal, D.J.1    Defranco, D.B.2
  • 57
    • 37549032769 scopus 로고    scopus 로고
    • Estrogen and progesterone are critical regulators of Stat5a expression in the mouse mammary gland
    • Santos, S.J., Haslam, S.Z. and Conrad, S.E. (2008) Estrogen and progesterone are critical regulators of Stat5a expression in the mouse mammary gland. Endocrinology, 149, 329-338.
    • (2008) Endocrinology , vol.149 , pp. 329-338
    • Santos, S.J.1    Haslam, S.Z.2    Conrad, S.E.3
  • 59
    • 0026780763 scopus 로고
    • Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland
    • Gavin, B.J. and McMahon, A.P. (1992) Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland. Mol. Cell. Biol., 12, 2418-2423.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2418-2423
    • Gavin, B.J.1    McMahon, A.P.2
  • 61
    • 77954530773 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 5a mediates mammary ductal branching and proliferation in the nulliparous mouse
    • Santos, S.J., Haslam, S.Z. and Conrad, S.E. (2010) Signal transducer and activator of transcription 5a mediates mammary ductal branching and proliferation in the nulliparous mouse. Endocrinology, 151, 2876-2885.
    • (2010) Endocrinology , vol.151 , pp. 2876-2885
    • Santos, S.J.1    Haslam, S.Z.2    Conrad, S.E.3
  • 62
    • 44349182073 scopus 로고    scopus 로고
    • Progesterone induction of the 11beta-hydroxysteroid dehydrogenase type 2 promoter in breast cancer cells involves coordinated recruitment of STAT5A and progesterone receptor to a distal enhancer and polymerase tracking
    • Subtil-Rodriguez, A., Millan-Arino, L., Quiles, I., Ballare, C., Beato, M. and Jordan, A. (2008) Progesterone induction of the 11beta-hydroxysteroid dehydrogenase type 2 promoter in breast cancer cells involves coordinated recruitment of STAT5A and progesterone receptor to a distal enhancer and polymerase tracking. Mol. Cell. Biol., 28, 3830-3849.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 3830-3849
    • Subtil-Rodriguez, A.1    Millan-Arino, L.2    Quiles, I.3    Ballare, C.4    Beato, M.5    Jordan, A.6
  • 63
  • 64
    • 33846590071 scopus 로고    scopus 로고
    • Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator activated receptor gamma
    • Burgermeister, E., Chuderland, D., Hanoch, T., Meyer, M., Liscovitch, M. and Seger, R. (2007) Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator activated receptor gamma. Mol. Cell. Biol., 27, 803-817.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 803-817
    • Burgermeister, E.1    Chuderland, D.2    Hanoch, T.3    Meyer, M.4    Liscovitch, M.5    Seger, R.6
  • 66
    • 16844370286 scopus 로고    scopus 로고
    • Order or chaos? An evaluation of the regulation of protein kinase CK2
    • Olsten, M.E. and Litchfield, D.W. (2004) Order or chaos? An evaluation of the regulation of protein kinase CK2. Biochem. Cell Biol., 82, 681-693.
    • (2004) Biochem. Cell Biol. , vol.82 , pp. 681-693
    • Olsten, M.E.1    Litchfield, D.W.2
  • 67
    • 84872818282 scopus 로고    scopus 로고
    • Dual-specificity MAP kinase phosphatases (MKPs) : Shaping the outcome of MAP kinase signalling
    • Caunt, C.J. and Keyse, S.M. (2013) Dual-specificity MAP kinase phosphatases (MKPs) : shaping the outcome of MAP kinase signalling. FEBS J., 280, 489-504.
    • (2013) FEBS J. , vol.280 , pp. 489-504
    • Caunt, C.J.1    Keyse, S.M.2
  • 68
    • 43049101029 scopus 로고    scopus 로고
    • Dual-specificity MAP kinase phosphatases (MKPs) and cancer
    • Keyse, S.M. (2008) Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev., 27, 253-261.
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 253-261
    • Keyse, S.M.1
  • 71
    • 0141481982 scopus 로고    scopus 로고
    • Gene profiling of a myeloma cell line reveals similarities and unique signatures among IL-6 response, N-ras-activating mutations, and coculture with bone marrow stromal cells
    • Croonquist, P.A., Linden, M.A., Zhao, F. and Van Ness, B.G. (2003) Gene profiling of a myeloma cell line reveals similarities and unique signatures among IL-6 response, N-ras-activating mutations, and coculture with bone marrow stromal cells. Blood, 102, 2581-2592.
    • (2003) Blood , vol.102 , pp. 2581-2592
    • Croonquist, P.A.1    Linden, M.A.2    Zhao, F.3    Van Ness, B.G.4
  • 73
    • 84862804003 scopus 로고    scopus 로고
    • Increased levels of DUSP6 phosphatase stimulate tumourigenesis in a molecularly distinct melanoma subtype
    • Li, W., Song, L., Ritchie, A.M. and Melton, D.W. (2012) Increased levels of DUSP6 phosphatase stimulate tumourigenesis in a molecularly distinct melanoma subtype. Pigment Cell Melanoma Res., 25, 188-199.
    • (2012) Pigment Cell Melanoma Res. , vol.25 , pp. 188-199
    • Li, W.1    Song, L.2    Ritchie, A.M.3    Melton, D.W.4
  • 75
    • 70450263302 scopus 로고    scopus 로고
    • Protein kinase Cdelta supports survival of MDA-MB-231 breast cancer cells by suppressing the ERK1/2 pathway
    • Lonne, G.K., Masoumi, K.C., Lennartsson, J. and Larsson, C. (2009) Protein kinase Cdelta supports survival of MDA-MB-231 breast cancer cells by suppressing the ERK1/2 pathway. J. Biol. Chem., 284, 33456-33465.
    • (2009) J. Biol. Chem. , vol.284 , pp. 33456-33465
    • Lonne, G.K.1    Masoumi, K.C.2    Lennartsson, J.3    Larsson, C.4
  • 76
    • 78649666066 scopus 로고    scopus 로고
    • Recent patents and advances in genomic biomarker discovery for colorectal cancers
    • Quyun, C., Ye, Z., Lin, S.C. and Lin, B. (2010) Recent patents and advances in genomic biomarker discovery for colorectal cancers. Recent Pat. DNA Gene Seq., 4, 86-93.
    • (2010) Recent Pat. DNA Gene Seq. , vol.4 , pp. 86-93
    • Quyun, C.1    Ye, Z.2    Lin, S.C.3    Lin, B.4
  • 77
    • 20444419344 scopus 로고    scopus 로고
    • Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
    • MacKeigan, J.P., Murphy, L.O. and Blenis, J. (2005) Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat. Cell Biol., 7, 591-600.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 591-600
    • MacKeigan, J.P.1    Murphy, L.O.2    Blenis, J.3
  • 78
    • 24044529771 scopus 로고    scopus 로고
    • Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas
    • Furukawa, T., Fujisaki, R., Yoshida, Y., Kanai, N., Sunamura, M., Abe, T., Takeda, K., Matsuno, S. and Horii, A. (2005) Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas. Mod Pathol, 18, 1034-1042.
    • (2005) Mod Pathol , vol.18 , pp. 1034-1042
    • Furukawa, T.1    Fujisaki, R.2    Yoshida, Y.3    Kanai, N.4    Sunamura, M.5    Abe, T.6    Takeda, K.7    Matsuno, S.8    Horii, A.9
  • 79
    • 80052295403 scopus 로고    scopus 로고
    • Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas
    • Messina, S., Frati, L., Leonetti, C., Zuchegna, C., Di Zazzo, E., Calogero, A. and Porcellini, A. (2011) Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas. Oncogene, 30, 3813-3820.
    • (2011) Oncogene , vol.30 , pp. 3813-3820
    • Messina, S.1    Frati, L.2    Leonetti, C.3    Zuchegna, C.4    Di Zazzo, E.5    Calogero, A.6    Porcellini, A.7
  • 80
    • 78751683777 scopus 로고    scopus 로고
    • Genomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs
    • Madak-Erdogan, Z., Lupien, M., Stossi, F., Brown, M. and Katzenellenbogen, B.S. (2011) Genomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs. Mol. Cell. Biol., 31, 226-236.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 226-236
    • Madak-Erdogan, Z.1    Lupien, M.2    Stossi, F.3    Brown, M.4    Katzenellenbogen, B.S.5
  • 81
    • 84861526574 scopus 로고    scopus 로고
    • Pioneer factors in hormone-dependent cancers
    • Jozwik, K.M. and Carroll, J.S. (2012) Pioneer factors in hormone-dependent cancers. Nat. Rev. Cancer, 12, 381-385.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 381-385
    • Jozwik, K.M.1    Carroll, J.S.2
  • 82
    • 80054084614 scopus 로고    scopus 로고
    • Pioneer factors: Directing transcriptional regulators within the chromatin environment
    • Magnani, L., Eeckhoute, J. and Lupien, M. (2011) Pioneer factors: directing transcriptional regulators within the chromatin environment. Trends Genet., 27, 465-474.
    • (2011) Trends Genet. , vol.27 , pp. 465-474
    • Magnani, L.1    Eeckhoute, J.2    Lupien, M.3
  • 84
    • 81755160905 scopus 로고    scopus 로고
    • PBX1 genomic pioneer function drives ERalpha signaling underlying progression in breast cancer
    • Magnani, L., Ballantyne, E.B., Zhang, X. and Lupien, M. (2011) PBX1 genomic pioneer function drives ERalpha signaling underlying progression in breast cancer. PLoS Genet., 7, e1002368.
    • (2011) PLoS Genet. , vol.7
    • Magnani, L.1    Ballantyne, E.B.2    Zhang, X.3    Lupien, M.4
  • 86
    • 79960072084 scopus 로고    scopus 로고
    • AP-2gamma regulates oestrogen receptor-mediated long-range chromatin interaction and gene transcription
    • Tan, S.K., Lin, Z.H., Chang, C.W., Varang, V., Chng, K.R., Pan, Y.F., Yong, E.L., Sung, W.K. and Cheung, E. (2011) AP-2gamma regulates oestrogen receptor-mediated long-range chromatin interaction and gene transcription. EMBO J., 30, 2569-2581.
    • (2011) EMBO J. , vol.30 , pp. 2569-2581
    • Tan, S.K.1    Lin, Z.H.2    Chang, C.W.3    Varang, V.4    Chng, K.R.5    Pan, Y.F.6    Yong, E.L.7    Sung, W.K.8    Cheung, E.9
  • 87
    • 77954530773 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 5a mediates mammary ductal branching and proliferation in the nulliparous mouse
    • Santos, S.J., Haslam, S.Z. and Conrad, S.E. (2010) Signal transducer and activator of transcription 5a mediates mammary ductal branching and proliferation in the nulliparous mouse. Endocrinology, 151, 2876-2885.
    • (2010) Endocrinology , vol.151 , pp. 2876-2885
    • Santos, S.J.1    Haslam, S.Z.2    Conrad, S.E.3
  • 89
    • 3142590865 scopus 로고    scopus 로고
    • Wnt signaling and breast cancer
    • Howe, L.R. and Brown, A.M. (2004) Wnt signaling and breast cancer. Cancer Biol. Ther., 3, 36-41.
    • (2004) Cancer Biol. Ther. , vol.3 , pp. 36-41
    • Howe, L.R.1    Brown, A.M.2
  • 90
    • 0034636153 scopus 로고    scopus 로고
    • Beta-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
    • Lin, S.Y., Xia, W., Wang, J.C., Kwong, K.Y., Spohn, B., Wen, Y., Pestell, R.G. and Hung, M.C. (2000) Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc. Natl Acad. Sci. USA, 97, 4262-4266.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 4262-4266
    • Lin, S.Y.1    Xia, W.2    Wang, J.C.3    Kwong, K.Y.4    Spohn, B.5    Wen, Y.6    Pestell, R.G.7    Hung, M.C.8
  • 91
    • 77449089469 scopus 로고    scopus 로고
    • Is there more to Wnt signalling in breast cancer than stabilisation of beta-catenin?
    • Collu, G.M., Meurette, O. and Brennan, K. (2009) Is there more to Wnt signalling in breast cancer than stabilisation of beta-catenin? Breast Cancer Res., 11, 105.
    • (2009) Breast Cancer Res. , vol.11 , pp. 105
    • Collu, G.M.1    Meurette, O.2    Brennan, K.3
  • 93
    • 0036112855 scopus 로고    scopus 로고
    • Loss of co-ordinate expression of progesterone receptors A and B is an early event in breast carcinogenesis
    • Mote, P.A., Bartow, S., Tran, N. and Clarke, C.L. (2002) Loss of co-ordinate expression of progesterone receptors A and B is an early event in breast carcinogenesis. Breast Cancer Res Treat, 72, 163-172.
    • (2002) Breast Cancer Res Treat , vol.72 , pp. 163-172
    • Mote, P.A.1    Bartow, S.2    Tran, N.3    Clarke, C.L.4
  • 94
    • 0033328138 scopus 로고    scopus 로고
    • Colocalization of progesterone receptors A and B by dual immunofluorescent histochemistry in human endometrium during the menstrual cycle
    • Mote, P.A., Balleine, R.L., McGowan, E.M. and Clarke, C.L. (1999) Colocalization of progesterone receptors A and B by dual immunofluorescent histochemistry in human endometrium during the menstrual cycle. J Clin Endocrinol Metab, 84, 2963-2971.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 2963-2971
    • Mote, P.A.1    Balleine, R.L.2    McGowan, E.M.3    Clarke, C.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.