Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 3, 2000, Pages 1032-1037

  Lange, Carol A ^b   Shen, Tianjie ^c   Horwitz, Kathryn B ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CALPASTATIN; LACTACYSTIN; MITOGEN ACTIVATED PROTEIN KINASE; PROGESTERONE RECEPTOR; PROTEASOME; PROTEASOME INHIBITOR; SERINE; UBIQUITIN;

AMINO ACID SUBSTITUTION; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONSENSUS SEQUENCE; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; LIGAND BINDING; MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; BREAST NEOPLASMS; CONSENSUS SEQUENCE; CYSTEINE ENDOPEPTIDASES; DOWN-REGULATION; ENZYME INHIBITORS; FEMALE; GLYCOPROTEINS; HELA CELLS; HUMANS; IMIDAZOLES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MULTIENZYME COMPLEXES; NEOPLASM PROTEINS; PHOSPHORYLATION; PHOSPHOSERINE; PROMEGESTONE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PYRIDINES; RECEPTORS, PROGESTERONE; RECOMBINANT FUSION PROTEINS; UBIQUITINS;

EID: 0033967491     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.3.1032     Document Type: Article

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