Peripheral metabotropic glutamate receptor subtype 5 contributes to inflammation-induced hypersensitivity of the rat temporomandibular joint

Journal of Molecular Neuroscience

Volumn 51, Issue 3, 2013, Pages 710-718

  Li, Bo ^a   Lu, Li ^a   Tan, Xuexin ^a   Zhong, Ming ^a   Guo, Yan ^a   Yi, Xin ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Complete Freund's adjuvant; mGluR5; Pain; Temporomandibular joint

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 5;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYPERSENSITIVITY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATION INDUCED HYPERSENSITIVITY; INFLAMMATORY PAIN; JAW DISEASE; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TEMPOROMANDIBULAR JOINT; TRIGEMINUS GANGLION; WESTERN BLOTTING;

ANIMALIA; RATTUS;

ANIMALS; FREUND'S ADJUVANT; INFLAMMATION; JOINT DISEASES; MALE; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, METABOTROPIC GLUTAMATE 5; TEMPOROMANDIBULAR JOINT; TRIGEMINAL GANGLION;

EID: 84885953432     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0052-2     Document Type: Article

References (54)

1. Ahn DK, Jung CY, Lee HJ, Choi HS, Ju JS, Bae YC (2004) Peripheral glutamate receptors participate in interlenkin-1 beta induced mechanical allodynia in the orofacial area of rats. Neurosci Lett 357:203-206
2. Bereiter DA, Cioffi JL, Bereiter DF, Zardeneta G, Milam SB (2006) Local blockade of integrins in the temporomandibular joint region reduces Fos-positive neurons in trigeminal subnucleus caudalis of female rats produced by jaw movement. Pain 125:65-73
3. Bhave G, Karim F, Carlton SM et al (2001) Peripheral group I metabotropic glutamate receptors modulate nociception in mice. Nat Neurosci 4:417-423
4. Carlton SM, Hargett GL, Coggeshan RE (1995) Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin. Neurosci Lett 197:25-28
5. Carr J, Wilhelm DL (1964) The evaluation of increased vascular permeability in the skin of guinea pigs. Aust J Exp Biol Med Sci 42:511-522
6. Chun YH, Ro JY (2010) Electrophysiological characterization of the rat trigeminal caudalis (Vc) neurons following intramuscular injection of capsaicin. Neurosci Lett 469:289-293
7. Coggeshall RE, Carlton SM (1998) Ultrastructural analysis of NMDA, AMPA, and kainite receptors on unmyelinated and myelinated axons in the peripheral. J Comp Neuro 391:78-86
8. Cosford ND, Tehrani L, Roppe J, Schweiger E, Smith ND, Anderson J, Bristow L, Brodkin J, Jiang X, McDonald I, Rao S, Washburn M, Varney MA (2003) 3- [(2-Methyl-1,3-thiazol-4-yl) ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity. Med Chem 46:204-207
9. Dogrul A, Ossipov MH, Lai J, Mala TP, Porreca F (2000) Peripheral and spinal anti-hyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGluR5)antagonist, in experimental neuropathic pain in rats. Neurosci Lett 292:115-118
10. Du J, Zhou S, Coggeshall RE, Carlton SM (2003) N-methyl-d-aspartate- induced excitation and sensitization of normal and inflamed nociceptors. Neuroscience 118:547-562
11. Flake NM, Hermanstyne TO, Gold MS (2006) Testosterone and estrogen have opposing actions on inflammation-induced plasma etravasation in the rat temporomandibular joint. Am J Physiol Regul Inteqr Comp Physiol 291:343-348
12. Gasparini F, Lingenhöhl K, Stoehr N, Flor PJ, Heinrich M, Vranesic I, Biollaz M, Allgeier H, Heckendorn R, Urwyler S, Varney MA, Johnson EC, Hess SD, Rao SP, Sacaan AI, Santori EM, Veliçelebi G, Kuhn R (1999) 2-Methyl-6-(phenylethynyl)-pyridine(MPEP), a potent, selective and systemically active mGlu5 receptor antagonist. Neuropharmacology 38:1493-1503
13. Harriott AM, Dessem D, Gold MS (2006) Inflammation increases the excitability of masseter muscle afferents. Neuroscience 141:433-442
14. Hathaway CB, Hu JW, Bereiter DA (1995) Distribution of Fos-like immunoreactivity in the caudal brainstem of the rat following noxious chemical stimulation of the temporomandibular joint. J Comp Neurol 356:444-456
15. Hudson LJ, Bevan S, McNair K, Gentry C, Fox A, Kuhn R, Winter J (2002) Metabotropic glutamate receptor 5 upregulation in A-fibers after spinal nerve injury: 2-methyl-6-(phenylethynyl)- pyridine (MPEP) reverses the induced thermal hyperalgesia. J Neurosci 22:2660-2668
16. Imbe H, Ren K (1999) Orofacial deep and cutaneous tissue inflammation differentially upregulates preprodynorphin mRNA in the trigeminal and paratrigeminal nuclei of the rat. Mol Brain Res 67:87-97
17. Imbe H, Iwata K, Zhou QQ, Zou S, Dubner R, Ren K (2001) Orofacial deep and cutaneous tissue inflammation and trigeminal neuronal activation. Implications for persistent temporomandibular pain. Cell Tissues Organs 169:238-247
18. Inquimbert P, Bartels K, Babaniyi OB, Barrett LB, Tegeder I, Scholz J (2012) Peripheral nerve injury produces a sustained shift in the balance between glutamate release and uptake in the dorsal horn of the spinal cord. Pain 153:2422-2431
19. Lam DK, Sessle BJ, Cairns BE, Hu JW (2005) Neural mechanisms of temporomandibular joint and masticatory muscle pain: a possible role for peripheral glutamate receptor mechanisms. Pain Res Manag 10:145-152
20. Lawand NB, Mcnearney T, Westlund KN (2000) Amino acid release into the knee joint: key role in nociception and inflammation. Pain 86:69-74
21. Lee J, Ro JY (2007a) Differential regulation of glutamate receptors in trigeminal ganglia following masseter inflammation. Neurosci Lett 421:91-95
22. Lee JS, Ro JY (2007b) Peripheral metabotropic glutamate receptor 5 mediates mechanical hypersensitivity in craniofacial muscle via protein kinase C dependent mechanisms. Neuroscience 146:375-38
23. Lee HJ, Choi HS, Ju JS, Bae YC, Kim SK, Yoon YW, Ahn DK (2008) Peripheral mGluR5 antagonist attenuated craniofacial muscle pain and inflammation but not mGluR1antagonist in lightly anesthetized rats. Brain Res Bull 76:8-15
24. List T, Axelsson S, Leijon G (2003) Pharmacologic interventions in the treatment of temporomandibular disorders, a typical facial pain and burning mouth syndrome. A qualitative systematic review. J Orofac Pain 17:301-310
25. Liu MG, Matsuura S, Shinoda M, Honda K, Suzuki I, Shibuta K, Tamagawa T, Katagiri A, Kiyomoto M, Ohara K, Furukawa A, Urata K, Iwata K (2012) Metabotropic glutamate receptor 5 contributes to inflammatory tongue pain via extracellular signal-regulated kinase signaling in the trigeminal spinal subnucleus caudalis and upper cervical spinal cord. J Neuroinflammation 9:258
26. Lobbezoo F, Drangsholt M, Peck C, Sato H, Kopp S, Svensson P (2004) Topical review: new insights into the pathology and diagnosis of disorders of the temporomandibular joint. J Orofac Pain 18:181-191
27. Lynn B, Shakhanbeh J (1988) Substance P content of the skin, neurogenic inflammation and numbers of C-fibers following capsaicin application to a cutaneous nerve in the rabbit. Neuroscience 24:769-775
28. Miranda HF, Romero MA, Puig MM (2012) Antinociceptive and anti-exudative synergism between dexketoprofen and tramadol in a model of inflammatory pain in mice. Fundam Clin Pharmacol 26(3):373-382
29. Oliveira MC, Parada CA, Veiga MC, Rodrigues LR, Barros SP, Tambeli CH (2005) Evidence for the involvement of endogenous ATP and P2X receptors in TMJ pain. Eur J Pain 9:87-93
30. Omite K, Kawamata T, Kawamata M, Namiki A (1998) Formalin-induced release of excitatory amino acids in the skin of the rat hindpaw. Brain Res 787:161-164
31. Pedroni CR, De Oliveira AS, Guaratini MI (2003) Prevalence study of signs and symptoms of temporomandibular disorders in university students. J Oral Rehabil 30:283-289
32. Ren K (1999) An improved method for assessing mechanical allodynia in the rat. Physiol Behav 67(5):711-716
33. Renk R, Dubner R (1999) Inflammatory models of pain and hyperalgesia. ILAR J 40:1118-8
34. Roveroni RC, Parada CA, Cecolia M, Verga FA, Tambeli CH (2001) Development of a behavioral model of TMJ pain in rats: the TMJ formalin test. Pain 94:185-191
35. Sessle BJ (2000) Acute and chronic craniofacial pain: brain stem mechanisms of nociceptive transmission and neuroplasticity and their clinical correlates. Crit Rev Oral Biol Med 11:57-91
36. Sessle BJ, Hu JW (1999) Mechanisms of pain arising from articular tissues. Can J Physiol Pharmaco l69:617-626
37. Svensson P, Cairns BE, Wang K, Hu JW, Graven-nielsen T, Arendt-nielsen L, Sessle BJ (2003) Glutamate-evoked pain and mechanical allodynia in the human masseter muscle. Pain 101:221-227
38. Svensson P, Wang K, Sessle BL, Arendt-Nielsen L (2004) Associations between pain and neuromuscular activity in the human jaw and neck muscles. Pain 109:225-232
39. Svensson P, Wang K, Arendt-Nielsen L, Cairns BE, Sessle BJ (2005) Pain effects of glutamate injections into human jaw or neck muscles. J Orofac Pain 19:109-118
40. Swift JQ, Roszkowski MT, Alton T, Hargreaves KM (1998) Effect of intra-articular versus systemic anti-inflammatory drugs in a rabbit model of temporomandibular joint inflammation. J Oral Maxillofac Surg 56:1288-1295
41. Takeda M, Tanimoto T, Ikeda M, Nasu M, Kadoi J, Shima Y, Ohta H, Matsumoto S (2005) Temporomandibular joint potentiates the excitabilities of trigeminal root ganglion neurons innervating the facial skin in rats. J Neurophysiol 93:2723-2738
42. Takeda M, Tanimoto T, Ikeda M, Nasu M, Kadoi J, Yoshida S, Matsumoto S (2006) Enhanced excitability of rat trigeminal root ganglion neurons. NeuroSci 138:621-630
43. Takeda M, Tanimoto T, Kadoi J, Nasu M, Takahashi M, Katanga J, Matsumoto S (2007) Enhanced excitability of nociceptive trigeminal ganglion neurons by satellite glial cytokine following peripheral inflammation. Pain 129:155-166
44. Walker K, Bowes M, Panesar M, Davis A, Gentry C, Kesingland A, Gasparini F, Spooren W, Stoehr N, Pagano A, Flor DJ, Vranesic I, Lingenhoehl K, Johnson EC, Varney M, VrbanI KR (2001a) Metabotropic glutamate receptor subtype 5 (mGluR5) and nociceptive function I selective blockade of mGluR5 receptor in models of acute, persistent and chronic pain. Neuropharmacology 40(1):1-9
45. Walker K, Reeve A, Bowes M, Winter J, Wotherspoon G, Davis A, Schmid P, Gasparini F, Kuhn R, Urban L (2001b) mGluR5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurons mediate inflammatory hyperalgesia. Neuropharmacology 40:10-19
46. Wang S, Song L, Tan Y, Ma Y, Tian Y, Jin X, Lim G, Zhang S, Chen L, Mao J (2012) A functional relationship between trigeminal astroglial activation and NR1 expression in a rat model of temporomandibular joint inflammation. Pain Med 13:1590-1600
47. Wheeler-Aceto H, Cowan A (1993) Naloxone causes apparent antinociception and pronociception simultaneously in the rat pain formalin test. Eur J Pharmaco l236:193-199
48. Xin S, Urban MO (2005) Effect of metabotropic glutamate receptor subtype 5 antagonist, 2-methyl-6-(phenylethynyl)-pyridine on mechanosensory afferents innervating rat hind paw following inflammation. Neurosci Lett 390:123-128
49. Yamazaki Y, Ren K, Shimada M, Iwata K (2008) Modulation of paratrigeminal nociceptive neurons following temporomandibular joint inflammation in rats. Exp Neurol 214:209-218
50. Young MR, Fleetwood-Walker SM, Mitchell R, Munro FE (1994) Evidence for a role of metabotropic glutamate receptors in sustained nociceptive inputs to rat dorsal horn neurons. Neuropharmacology 33:141-144
51. Yu XM, Sessle BJ, Vernon H, Hu JW (1995) Effects of inflammatory irritant application to the rat temporomandibular joint on jaw and neck muscle activity. Pain 60:143-149
52. Yu XM, Sessle BJ, Haas DA, Izzo A, Vernon H, Hu JW (1996) Involvement of NMDA receptor mechanisms in jaw electromyographic activity and plasma extravasation induced by inflammatory irritant application to temporomandibular joint region of rats. Pain 68:169-178
53. Zammataro M, Chiechio S, Montana MC, Traficante A, Copani A, Nicoletti F, Gereau RW (2011) mGlu2 metabotropic glutamate receptor restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists. Mol Pain 7:3-5
54. Zhu CZ, Hsieh G, Ei-Kouhen O, Wilson SG, Mikusa JP, Hollingsworth PR, Chang R, Moreland RB, Brioni J, Decker MW, Honore P (2005) Role of central and peripheral mGlu5 receptors in post-operative pain in rats. Pain 114:195-202