Electrophysiological characterization of the rat trigeminal caudalis (Vc) neurons following intramuscular injection of capsaicin

Neuroscience Letters

Volumn 469, Issue 3, 2010, Pages 289-293

  Chun, Yang H ^b   Ro, Jin Y ^a,b  

^a UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^b Kyung Hee University   (South Korea)

Author keywords

Brainstem neurons; Muscle pain; Peripheral glutamate receptors

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; CAPSAICIN; METABOTROPIC RECEPTOR 5;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; DRUG EFFICACY; MALE; MASSETER MUSCLE; MECHANICAL STIMULATION; MUSCLE INJURY; MYALGIA; MYOSITIS; NERVE CELL EXCITABILITY; NONHUMAN; PERCEPTIVE THRESHOLD; PRIORITY JOURNAL; RAT; SENSORY STIMULATION; SKIN RECEPTOR; STIMULUS RESPONSE; TRIGEMINAL NUCLEUS;

ANIMALS; CAPSAICIN; EVOKED POTENTIALS; EXCITATORY AMINO ACID ANTAGONISTS; INJECTIONS, INTRAMUSCULAR; MALE; MASSETER MUSCLE; MICROELECTRODES; NEURONS; PAIN; PHYSICAL STIMULATION; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SENSORY SYSTEM AGENTS; TRIGEMINAL CAUDAL NUCLEUS;

EID: 73649138190     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.10.012     Document Type: Article

References (21)

1. Arima T., Svensson P., and Arendt-Nielsen L. Capsaicin-induced muscle hyperalgesia in the exercised and non-exercised human masseter muscle. J. Orofac. Pain 14 (2000) 213-223
2. Arima T., Arendt-Nielsen L., Minagi S., and Svensson P. Effect of capsaicin-evoked jaw-muscle pain on intramuscular blood-flow. Arch. Oral Biol. 54 (2009) 241-249
3. Capra N.F., and Ro J.Y. Human and animal experimental models of acute and chronic muscle pain: intramuscular algesic injection. Pain 110 (2004) 3-7
4. Carstens E., Kuenzler N., and Handwerker H.O. Activation of neurons in rat trigeminal subnucleus caudalis by different irritant chemicals applied to oral or ocular mucosa. J. Neurophysiol. 80 (1998) 465-492
5. Chun Y.H., Frank D., Lee J.S., Zhang Y., Auh Q.S., and Ro J.Y. Peripheral AMPA receptors contribute to muscle nociception and c-fos activation. Neurosci. Res. 62 (2008) 97-104
6. Dessirier J.M., Simons C.T., Sudo M., Sudo S., and Carstens E. Sensitization, desensitization and stimulus-induced recovery of trigeminal neuronal responses to oral capsaicin and nicotine. J. Neurophysiol. 84 (2000) 1851-1862
7. Du J., Koltzenburg M., and Carlton S.M. Glutamate-induced excitation and sensitization of nociceptors in rat glabrous skin. Pain 89 (2001) 187-198
8. Du J., Zhou S., Coggeshall R.E., and Carlton S.M. N-Methyl-d-aspartate-induced excitation and sensitization of normal and inflamed nociceptors. Neuroscience 118 (2003) 547-562
9. Dubner R., and Ruda M.A. Activity-dependent neuronal plasticity following tissue injury and inflammation. Trends Neurosci. 15 (1992) 96-103
10. Hu J.W., Sessle B.J., Raboisson P., Dallel R., and Woda A. Stimulation of craniofacial muscle afferents induces prolonged facilitatory effects in trigeminal nociceptive brain-stem neurones. Pain 48 (1992) 53-60
11. Lam D.K., Sessle B.J., and Hu J.W. Glutamate and capsaicin effects on trigeminal nociception. II. Activation and central sensitization in brainstem neurons with deep craniofacial afferent input. Brain Res. 1253 (2009) 48-59
12. Lawand N.B., McNearney T., and Westlund K.N. Amino acid release into the knee joint: key role in nociception and inflammation. Pain 86 (2000) 69-74
13. Lee J.S., and Ro J.Y. Peripheral metabotropic glutamate receptor 5 mediates mechanical hypersensitity in craniofacial muscle via protein kinase C dependent mechanisms. Neuroscience 146 (2007) 375-383
14. Lee H.J., Choi H.S., Ju J.S., Bae Y.C., Kim S.K., Yoon Y.W., and Ahn D.K. Peripheral mGluR5 antagonist attenuated craniofacial muscle pain and inflammation but not mGluR1 antagonist in lightlyanesthetized rats. Brain Res. Bull. 70 (2006) 78-385
15. J.S. Lee, Y. Zhang, J.Y. Ro, Involvement of neuronal, inducible, and endothelia nitric oxide synthases in capsaicin-induced muscle hypersensitivity, Eur. J. Pain (2008), doi:10.1016/j.ejpain.2008.11.009.
16. Ro J.Y. Contribution of peripheral NMDA receptors in craniofacial muscle nociception and edema formation. Brain Res. 979 (2003) 78-84
17. Ro J.Y. Functional role of peripheral glutamate receptors in craniofacial muscle pain and hyperalgesia. In: Graven-Nielsen T., Arendt-Nielsen L., and Mense S. (Eds). Fundamentals of Musculoskeletal Pain (2008), IASP Press, Seattle 33-45
18. Ro J.Y., Lee J., Capra N.F., and Zhang Y. Role of soluble guanylatecyclase in the trigeminal subnucleus caudalis incapsaicin-induced muscle hypersensitivity. Brain Res. 1184 (2007) 141-148
19. Ro J.Y., Lee J.S., and Zhang Y. Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia. Pain 144 (2009) 270-277
20. Ushida T., Tani T., Kawasaki M., Iwatsu O., and Yamamoto H. Peripheral administration of an N-methyl-d-aspartate receptor antagonist (MK-801) changes dorsal horn neuronal responses in rats. Neurosci. Lett. 260 (1999) 89-92
21. Wang K., Arendt-Nielsen L., and Svensson P. Capsaicin-induced muscle pain alters the excitability of the human jaw-stretch reflex. J. Dent. Res. 81 (2002) 650-654