Inflammatory models of pain and hyperalgesia

ILAR Journal

Volumn 40, Issue 3, 1999, Pages 111-118

  Ren, Ke ^a   Dubner, Ronald ^a  

^a UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001316768     PISSN: 10842020     EISSN: None     Source Type: Journal    
DOI: 10.1093/ilar.40.3.111     Document Type: Article

References (67)

1. Abbadie C, Taylor KT, Peterson MA, Basbaum AI. 1997. Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the rat spinal cord: Studies with remifentanil and lidocaine. Pain 69:101-110.
2. Abbott FV, Franklin KBJ, Westbrook RF. 1995. The formalin test: Scoring properties of the first and second phases of the pain response in rats. Pain 60:91-102.
3. Bullitt E. 1990. Expression of c-fos-like protein as a marker for neuronal activity following noxious stimulation in the rat. J Comp Neurol 296:517-530.
4. Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL. 1994. Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods 53:55-63.
5. Clavelou P, Dallel R, Orliaguet T, Woda A, Raboisson P. 1995. The orofacial formalin test in rats: Effects of different formalin concentrations. Pain 62:295-301.
6. Clavelou P, Pajot J, Dallel R, Raboisson P. 1989. Application of the formalin test to the study of orofacial pain in the rat. Neurosci Lett 103:349-353.
7. Coderre TJ, Wall PD. 1987. Ankle joint urate arthritis (AJUA) in rats: An alternative animal model of arthritis to that produced by Freund's adjuvant. Pain 28:379-393.
8. De Castro Costa M, De Sutter P, Gybels J, Van Hees J. 1981. Adjuvant-induced arthritis in rats: A possible animal model of chronic pain. Pain 10:173-186.
9. Dougherty PM, Sluka KA, Sorkin LS, Westlund KN, Willis WD. 1992. Neural changes in acute arthritis in monkeys. 1. Parallel enhancement of responses of spinothalamic tract neurons to mechanical stimulation and excitatory amino acids. Brain Res Rev 17:1-13.
10. Draisci G, Iadarola MJ. 1989. Temporal analysis of increases in c-fos, preprodynorphin and preproenkephalin mRNAs in rat spinal cord. Mol Brain Res 6:31-37.
11. Dubner R. 1983. Pain research in animals. Ann NY Acad Sci 406:128-132.
12. Dubuisson D, Dennis SG. 1977. The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain-stem stimulation in rats and cats. Pain 4:161174.
13. Gilchrist HD, Allard BL, Simone DA. 1996. Enhanced withdrawal responses to heat and mechanical stimuli following intraplantar injection of capsaicin in rats. Pain 67:179-188.
14. Goelet P, Castellucci VF, Schacher S, Kandel ER. 1986. The long and short of long-term memory - A molecular framework. Nature 322:419-422.
15. Gogas KR, Presley RW, Levine JD, Basbaum AI. 1991. The antinociceptive action of supraspinal opioids results from an increase in descending inhibitory control: Correlation of nociceptive behavior and c-fos expression. Neuroscience 42:617-628.
16. Haas DA, Nakanishi O, MacMillan RE, Jordan RC, Hu JW. 1992. Development of an orofacial model of acute inflammation in the rat. Arch Oral Biol 37:417-422.
17. Hargreaves K, Dubner R, Brown F, Flores C, Joris J. 1988. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77-88.
18. Hoheisel U, Koch K, Mense S. 1994. Functional reorganization in the rat dorsal horn during an experimental myositis. Pain 59:111-118.
19. Hoheisel U, Sander B, Mense S. 1997. Myositis-induced functional reorganisation of the rat dorsal horn: Effects of spinal superfusion with antagonists to neurokinin and glutamate receptors. Pain 69:219-230.
20. Houghton AK, Hewitt E, Westlund KN. 1997. Enhanced withdrawal responses to mechanical and thermal stimuli after bone injury. Pain 73:325-337.
21. Hu JW, Sessle BJ, Raboisson P, Dallel R, Woda A. 1992. Stimulation of craniofacial muscle afferents induces prolonged facilitatory effects in trigeminal nociceptive brain-stem neurones. Pain 48:53-60.
22. Hu JW, Yu X-M, Sunakawa M, Chiang CY, Haas DA, Kwan CL, Tsai C-M, Vernon H, Sessle BJ. 1994. Electromyographic and trigeminal brainstem neuronal changes associated with inflammatory irritation of superficial and deep craniofacial tissues in rats. In: Gebhart GF, Hammond DL, Jensen TS, editors. Proc 7th World Congress on Pain. Elsevier, Amsterdam, p 325-336.
23. Hunt SP , Pini A, Even G. 1987. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature 328:632-634.
24. Hylden JLK, Nahin RL, Traub RJ, Dubner R. 1989. Expansion of receptive fields of spinal lamina I projection neurons in rats with unilateral adjuvant-induced inflammation: The contribution of dorsal horn mechanisms. Pain 37:229-243.
25. Iadarola MJ, Brady LS, Draisci G, Dubner R. 1988a. Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: Stimulus specificity, behavioral parameters and opioid receptor binding. Pain 45:313-326.
26. Iadarola MJ, Douglass J, Civelli O, Naranjo JR. 1988b. Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: Evidence using cDNA hybridization. Brain Res 455:202-212.
27. Imamura Y, Kawamoto H, Nakanishi O. 1997. Characterization of heat-hyperalgesia in an experimental trigeminal neuropathy in rats. Exp Brain Res 116:97-103.
28. Imbe H, Dubner R, Ren K. 1998. Masseter inflammation-induced Fos protein expression in brainstem neurons depends on somatosensory-vagal-adrenal integration. (Abstract). Soc Neurosci Abs 24:388.
29. Kaneko M, Hammond DL. 1997. Role of spinal gamma-aminobutyric acid A receptors in formalin-induced nociception in the rat. J Pharmacol Exp Ther 282:928-38.
30. Kayser V, Guilbaud G. 1987. Local and remote modifications of nociceptive sensitivity during carrageenin-induced inflammation in the rat. Pain 28:99-107.
31. Kim SH, Chung JM. 1992. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50:355-363.
32. LaMotte RH, Shain CN, Simone DA, Tsai E-FP. 1991. Neurogenic hyperalgesia: Psychophysical studies of underlying mechanisms. J Neurophysiol 66:190-211.
33. Larson AA, Brown DR, El-Atrash S, Walser MM. 1986. Pain threshold changes in adjuvant-induced inflammation: A possible model of chronic pain in the mouse. Pharmacol Biochem Behav 24:49-53.
34. Ma Q-P, Woolf CJ. 1996a. Progressive tactile hypersensitivity: An inflammation-induced incremental increase in the excitability of the spinal cord. Pain 67:97-106.
35. Ma Q-P, Woolf CJ. 1996b. Basal and touch-evoked fos-like immunoreactivity during experimental inflammation in the rat. Pain 67:307-316.
36. Meller ST, Gebhart GF. 1997. Intraplantar zymosan as a reliable, quantifiable model of thermal and mechanical hyperalgesia in the rat. Eur J Pain 1:43-52.
37. Menétrey D, Gannon A, Levine JD, Basbaum AI. 1989. Expression of c-fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular, and visceral stimulation. J Comp Neurol 285:177-195.
38. Mense S. 1991. Considerations concerning the neurobiological basis of muscle pain. Can J Physiol Pharmacol 69:610-616.
39. Mersky H. 1979. Pain terms: A list with definitions and notes on usage. Pain 6:249-252.
40. Millan MJ, Czlonkowski A, Morris B, Stein C, Arendt R, Huber A, Höllt V, Herz A. 1988. Inflammation of the hind limb as a model of unilateral, localized pain: Influence on multiple opioid systems in the spinal cord of the rat. Pain 35:299-312.
41. Ness TJ. 1999. Models of visceral nociception. ILAR J 40:119-128.
42. Neumann S, Doubell TP , Leslie T, Woolf CJ. 1996. Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons. Nature 384:360-364.
43. Okuda K, Nakahama H, Miyakawa H, Shima K. 1984. Arthritis induced in cats by sodium urate: A possible animal model for chronic pain. Pain 18:287-297.
44. Presley RW, Menétrey D, Levine JD, Basbaum AI. 1990. Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord. J Neurosci 10:323-335.
45. Puig S, Sorkin LS. 1996. Formalin-evoked activity in identified primary afferent fibers: Systemic lidocaine suppresses phase-2 activity. Pain 64:345-355.
46. Qiu C, Sora I, Ren K, Uhl G, Dubner R. 1998. Opioid receptor plasticity in mu opioid receptor knockout (MOR KO) mice following persistent inflammation. (Abstract). Soc Neurosci Abs 24:892.
47. Ren K, Dubner R. 1993. NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpaw. Neurosci Lett 163:22-26.
48. Ren K, Dubner R. 1996. An inflammation/hyperalgesia model for the study of orofacial pain. (Abstract). J Dent Res 75:217.
49. Ren K, Hylden JLK, Williams GM, Ruda MA, Dubner R. 1992. The effects of an NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with adjuvant-induced inflammation. Pain 50:331-344.
50. Ren K, Ruda MA. 1996. Descending modulation of Fos expression after persistent peripheral inflammation. Neuroreport 7:2186-2190.
51. Schaible H-G, Schmidt RF, Willis WD. 1987. Enhancement of the responses of ascending tract cells in the cat spinal cord by acute inflammation of the knee joint. Exp Brain Res 66:489-499.
52. Simone DA, Sorkin LS, Oh U, Chung JM, Owens C, LaMotte RH, Willis WD. 1991. Neurogenic hyperalgesia: Central neural correlates in responses of spinothalamic tract neurons. J Neurophysiol 66:228-246.
53. Slart R, Yu AL, Yaksh TL, Sorkin LS. 1997. An animal model of pain produced by systemic administration of an immunotherapeutic anti-ganglioside antibody. Pain 69:119-125.
54. Sluka KA, Westlund KN. 1993. Behavioral and immunohistochemical changes in an experimental arthritis model in rats. Pain 55:367-377.
55. Sternbach RA. 1976. The need for an animal model of chronic pain. Pain 2:2-4.
56. Stohler CS, Zhang X, Ashton-Miller JA. 1991. An experimental model of jaw muscle pain in man. In: Davidovitch Z, editor. The Biological Mechanisms of Tooth Movement and Craniofacial Adaptation. Birmingham: EBSCO Media, p 261-267.
57. Taylor BK, Peterson MA, Basbaum AI. 1995. Persistent chemical nociception in the rat requires ongoing peripheral nerve input. J Neurosci 15:7575-7584.
58. Toms S, Benevento LA, Capra NF. 1996. Jaw position task performance during acute muscle pain in monkeys. (Abstract). J Dent Res 75:133.
59. van der Laan L, Kapitein PJ, Verhofstad AA, Hendriks T, Goris RJ. 1997. A novel animal model to evaluate oxygen derived free radical damage in soft tissue. Free Radic Res 26:363-372.
60. Vos BP, Strassman AM, Maciewicz RJ. 1994. Behavioral evidence of trigeminal neuropathic pain following chronic constriction injury to the rat's infraorbital nerve. J Neurosci 14:2708-2723.
61. Vyklicky L. 1979. Techniques for the study of pain in animals. In: Bonica JJ, Liebeskind JC, Albe-Fessard DG, editors. Advances in Pain Research and Therapy. Vol 3. New York NY: Raven Press, p 727-745.
62. Wei F, Dubner R, Ren K. 1999. Nucleus reticularis gigantocellularis and nucleus raphe magnus in the brain stem exert opposite effects on behavioral hyperalgesia and spinal Fos protein expression after peripheral inflammation. Pain 80:127-141.
63. Wei F, Ren K, Dubner R. 1998. Inflammation-induced Fos protein expression in the rat spinal cord is enhanced following dorsolateral or ventrolateral funiculus lesions. Brain Res 782:136-141.
64. Woolf CJ, Thompson SW. 1991. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation: Implications for the treatment of post-injury pain hypersensitivity states. Pain 44:293-299.
65. Yu X-M, Sessle BJ, Hu JW. 1993. Differential effects of cutaneous and deep application of inflammatory irritant on mechanoreceptive field properties of trigeminal brain stem nociceptive neurons. J Neurophysiol 70:1704-1707.
66. Yu X-M, Sessle BJ, Vernon H, Hu JW. 1994. Administration of opiate antagonist naloxone induces recurrence of increased jaw muscle activities related to inflammatory irritant application to rat temporomandibular joint region. J Neurophysiol 72:1430-1433.
67. Zhou Q-Q, Imbe H, Dubner R, Ren K. 1997. Persistent Fos protein expression after orofacial deep or cutaneous tissue inflammation. (Abstract). Soc Neurosci Abstr 23:1809.