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Volumn 50, Issue 5, 2013, Pages 586-594

Structural and dynamical aspects of skin studied by multiphoton excitation fluorescence microscopy-based methods This article is dedicated to the loving memory of Prof. Robert (Bob) Clegg

Author keywords

Fluorescence lifetime imaging; LAURDAN generalized polarization function; Multiphoton excitation fluorescence microscopy; Raster image correlation spectroscopy

Indexed keywords

2,7 BIS (2 CARBOXYETHYL) 5 CARBOXYFLUORESCEIN; 2,7 BIS (2 CARBOXYETHYL) 6 CARBOXYFLUORESCEIN; CARBOXYL GROUP; FLUORESCEIN; LAURDAN; LIPOSOME; PROTON; UNCLASSIFIED DRUG;

EID: 84885951602     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.04.010     Document Type: Review
Times cited : (13)

References (75)
  • 3
    • 84864279732 scopus 로고    scopus 로고
    • Fluorescence recovery after photo-bleaching as a method to determine local diffusion coefficient in the stratum corneum
    • Y.G. Anissimov, X. Zhao, M.S. Roberts, and A.V. Zvyagin Fluorescence recovery after photo-bleaching as a method to determine local diffusion coefficient in the stratum corneum Int. J. Pharm. 435 2012 93 97
    • (2012) Int. J. Pharm. , vol.435 , pp. 93-97
    • Anissimov, Y.G.1    Zhao, X.2    Roberts, M.S.3    Zvyagin, A.V.4
  • 4
    • 33749046710 scopus 로고    scopus 로고
    • To see or not to see: Lateral organization of biological membranes and fluorescence microscopy
    • DOI 10.1016/j.bbamem.2006.05.019, PII S0005273606002033
    • L.A. Bagatolli To see or not to see: lateral organization of biological membranes and fluorescence microscopy Biochim. Biophys. Acta 1758 2006 1541 1556 (Pubitemid 44466696)
    • (2006) Biochimica et Biophysica Acta - Biomembranes , vol.1758 , Issue.10 , pp. 1541-1556
    • Bagatolli, L.A.1
  • 5
    • 0032826460 scopus 로고    scopus 로고
    • Two-photon fluorescence microscopy observation of shape changes at the phase transition in phospholipid giant unilamellar vesicles
    • L.A. Bagatolli, and E. Gratton Two-photon fluorescence microscopy observation of shape changes at the phase transition in phospholipid giant unilamellar vesicles Biophys. J. 77 1999 2090 2101 (Pubitemid 29463170)
    • (1999) Biophysical Journal , vol.77 , Issue.4 , pp. 2090-2101
    • Bagatolli, L.A.1    Gratton, E.2
  • 6
    • 74149087439 scopus 로고    scopus 로고
    • New insights into the mode of action of ultradeformable vesicles using calcein as hydrophilic fluorescent marker
    • A.P.C.O. Bahia, E.G. Azevedo, L.A.M. Ferreira, and F. Frezard New insights into the mode of action of ultradeformable vesicles using calcein as hydrophilic fluorescent marker Eur. J. Pharm. Sci. 39 2010 90 96
    • (2010) Eur. J. Pharm. Sci. , vol.39 , pp. 90-96
    • Bahia, A.P.C.O.1    Azevedo, E.G.2    Ferreira, L.A.M.3    Frezard, F.4
  • 9
    • 79952007662 scopus 로고    scopus 로고
    • Major translocation of calcium upon epidermal barrier insult: Imaging and quantification via FLIM/Fourier vector analysis
    • M.J. Behne, S. Sanchez, N.P. Barry, N. Kirschner, W. Meyer, T.M. Mauro, I. Moll, and E. Gratton Major translocation of calcium upon epidermal barrier insult: imaging and quantification via FLIM/Fourier vector analysis Arch. Dermatol. Res. 303 2011 103 115
    • (2011) Arch. Dermatol. Res. , vol.303 , pp. 103-115
    • Behne, M.J.1    Sanchez, S.2    Barry, N.P.3    Kirschner, N.4    Meyer, W.5    Mauro, T.M.6    Moll, I.7    Gratton, E.8
  • 10
    • 0028869663 scopus 로고
    • Two-photon fluorescence correlation spectroscopy: Method and application to the intracellular environment
    • K.M. Berland, P.T. So, and E. Gratton Two-photon fluorescence correlation spectroscopy: method and application to the intracellular environment Biophys. J. 68 1995 694 701
    • (1995) Biophys. J. , vol.68 , pp. 694-701
    • Berland, K.M.1    So, P.T.2    Gratton, E.3
  • 12
    • 84856015747 scopus 로고    scopus 로고
    • Structural characterization and lipid composition of acquired cholesteatoma: A comparative study with normal skin
    • M. Bloksgaard, V. Svane-Knudsen, J.A. Sorensen, L. Bagatolli, and J. Brewer Structural characterization and lipid composition of acquired cholesteatoma: a comparative study with normal skin Otol. Neurotol. 33 2012 177 183
    • (2012) Otol. Neurotol. , vol.33 , pp. 177-183
    • Bloksgaard, M.1    Svane-Knudsen, V.2    Sorensen, J.A.3    Bagatolli, L.4    Brewer, J.5
  • 16
    • 44449177454 scopus 로고    scopus 로고
    • First order optical nonlinearities chi(2) for organic nanofibers from functionalized para-phenylenes
    • J. Brewer, M. Schiek, I. Wallmann, and H.G. Rubahn First order optical nonlinearities chi(2) for organic nanofibers from functionalized para-phenylenes Opt. Commun. 281 2008 3892 3896
    • (2008) Opt. Commun. , vol.281 , pp. 3892-3896
    • Brewer, J.1    Schiek, M.2    Wallmann, I.3    Rubahn, H.G.4
  • 18
    • 84876666769 scopus 로고    scopus 로고
    • Spatially resolved two-color diffusion measurements in human skin applied to transdermal liposome penetration
    • 10.1038/jid.2012.461 (Epub ahead of print)
    • J. Brewer, M. Bloksgaard, J. Kubiak, J.A. Sorensen, and L.A. Bagatolli Spatially resolved two-color diffusion measurements in human skin applied to transdermal liposome penetration J. Invest. Dermatol. 2012 10.1038/jid.2012.461 (Epub ahead of print)
    • (2012) J. Invest. Dermatol.
    • Brewer, J.1    Bloksgaard, M.2    Kubiak, J.3    Sorensen, J.A.4    Bagatolli, L.A.5
  • 19
    • 76549132629 scopus 로고    scopus 로고
    • Second harmonic generation microscopy: A tool for spatially and temporally resolved studies of heat induced structural changes in meat
    • D.A. Bruggemann, J. Brewer, J. Risbo, and L. Bagatolli Second harmonic generation microscopy: a tool for spatially and temporally resolved studies of heat induced structural changes in meat Food Biophys. 5 2010 1 8
    • (2010) Food Biophys. , vol.5 , pp. 1-8
    • Bruggemann, D.A.1    Brewer, J.2    Risbo, J.3    Bagatolli, L.4
  • 20
    • 0242385409 scopus 로고    scopus 로고
    • Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms
    • DOI 10.1038/nbt894
    • P.J. Campagnola, and L.M. Loew Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms Nat. Biotechnol. 21 2003 1356 1360 (Pubitemid 37356622)
    • (2003) Nature Biotechnology , vol.21 , Issue.11 , pp. 1356-1360
    • Campagnola, P.J.1    Loew, L.M.2
  • 21
    • 54849413554 scopus 로고    scopus 로고
    • Pig skin structure and transdermal delivery of liposomes: A two photon microscopy study
    • D.C. Carrer, C. Vermehren, and L.A. Bagatolli Pig skin structure and transdermal delivery of liposomes: a two photon microscopy study J. Control Release 132 2008 12 20
    • (2008) J. Control Release , vol.132 , pp. 12-20
    • Carrer, D.C.1    Vermehren, C.2    Bagatolli, L.A.3
  • 22
    • 84885960451 scopus 로고    scopus 로고
    • Detection of calcium gradients in live ex vivo human epidermis using a novel approach based on phasor analysis of two-photon excitation Fluorescence Lifetime Imaging (FLIM)
    • A. Celli, S.A. Sanchez, M. Behne, T. Hazelet, E. Gratton, and T. Mauro Detection of calcium gradients in live ex vivo human epidermis using a novel approach based on phasor analysis of two-photon excitation Fluorescence Lifetime Imaging (FLIM) J. Invest. Dermatol. 129 2009 S73
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 73
    • Celli, A.1    Sanchez, S.A.2    Behne, M.3    Hazelet, T.4    Gratton, E.5    Mauro, T.6
  • 23
    • 77749315803 scopus 로고    scopus 로고
    • The epidermal Ca(2+) gradient: Measurement using the phasor representation of fluorescent lifetime imaging
    • A. Celli, S. Sanchez, M. Behne, T. Hazlett, E. Gratton, and T. Mauro The epidermal Ca(2+) gradient: measurement using the phasor representation of fluorescent lifetime imaging Biophys. J. 98 2010 911 921
    • (2010) Biophys. J. , vol.98 , pp. 911-921
    • Celli, A.1    Sanchez, S.2    Behne, M.3    Hazlett, T.4    Gratton, E.5    Mauro, T.6
  • 25
    • 0038357909 scopus 로고    scopus 로고
    • Transdermal drug delivery of insulin with ultradeformable carriers
    • DOI 10.2165/00003088-200342050-00004
    • G. Cevc Transdermal drug delivery of insulin with ultradeformable carriers Clin. Pharmacokinet. 42 2003 461 474 (Pubitemid 36649039)
    • (2003) Clinical Pharmacokinetics , vol.42 , Issue.5 , pp. 461-474
    • Cevc, G.1
  • 26
    • 1542268930 scopus 로고    scopus 로고
    • Lipid vesicles and other colloids as drug carriers on the skin
    • DOI 10.1016/j.addr.2003.10.028, PII S0169409X03002448
    • G. Cevc Lipid vesicles and other colloids as drug carriers on the skin Adv. Drug Deliv. Rev. 56 2004 675 711 (Pubitemid 38326939)
    • (2004) Advanced Drug Delivery Reviews , vol.56 , Issue.5 , pp. 675-711
    • Cevc, G.1
  • 27
    • 0029118279 scopus 로고
    • Transdermal drug carriers - Basic properties, optimization and transfer efficiency in the case of epicutaneously applied peptides
    • G. Cevc, A. Schatzlein, and G. Blume Transdermal drug carriers - basic properties, optimization and transfer efficiency in the case of epicutaneously applied peptides J. Controlled Release 36 1995 3 16
    • (1995) J. Controlled Release , vol.36 , pp. 3-16
    • Cevc, G.1    Schatzlein, A.2    Blume, G.3
  • 28
    • 0032545780 scopus 로고    scopus 로고
    • Ultraflexible vesicles, transfersomes, have an extremely low pore penetration resistance and transport therapeutic amounts of insulin across the intact mammalian skin
    • DOI 10.1016/S0005-2736(97)00177-6, PII S0005273697001776
    • G. Cevc, D. Gebauer, J. Stieber, A. Schatzlein, and G. Blume Ultraflexible vesicles, transfersomes, have an extremely low pore penetration resistance and transport therapeutic amounts of insulin across the intact mammalian skin Biochim. Biophys. Acta 1368 1998 201 215 (Pubitemid 28031874)
    • (1998) Biochimica et Biophysica Acta - Biomembranes , vol.1368 , Issue.2 , pp. 201-215
    • Cevc, G.1    Gebauer, D.2    Stieber, J.3    Schatzlein, A.4    Blume, G.5
  • 29
    • 0037136041 scopus 로고    scopus 로고
    • Ultradeformable lipid vesicles can penetrate the skin and other semi-permeable barriers unfragmented. Evidence from double label CLSM experiments and direct size measurements
    • DOI 10.1016/S0005-2736(02)00401-7, PII S0005273602004017
    • G. Cevc, A. Schatzlein, and H. Richardsen Ultradeformable lipid vesicles can penetrate the skin and other semi-permeable barriers unfragmented. Evidence from double label CLSM experiments and direct size measurements Biochim. Biophys. Acta 1564 2002 21 30 (Pubitemid 34717865)
    • (2002) Biochimica et Biophysica Acta - Biomembranes , vol.1564 , Issue.1 , pp. 21-30
    • Cevc, G.1    Schatzlein, A.2    Richardsen, H.3
  • 30
    • 0025342635 scopus 로고
    • 2-Photon laser scanning fluorescence microscopy
    • W. Denk, J.H. Strickler, and W.W. Webb 2-Photon laser scanning fluorescence microscopy Science 248 1990 73 76
    • (1990) Science , vol.248 , pp. 73-76
    • Denk, W.1    Strickler, J.H.2    Webb, W.W.3
  • 31
    • 23244441649 scopus 로고    scopus 로고
    • Measuring fast dynamics in solutions and cells with a laser scanning microscope
    • DOI 10.1529/biophysj.105.062836
    • M.A. Digman, C.M. Brown, P. Sengupta, P.W. Wiseman, A.R. Horwitz, and E. Gratton Measuring fast dynamics in solutions and cells with a laser scanning microscope Biophys. J. 89 2005 1317 1327 (Pubitemid 41099013)
    • (2005) Biophysical Journal , vol.89 , Issue.2 , pp. 1317-1327
    • Digman, M.A.1    Brown, C.M.2    Sengupta, P.3    Wiseman, P.W.4    Horwitz, A.R.5    Gratton, E.6
  • 32
    • 17844394185 scopus 로고    scopus 로고
    • Fluctuation correlation spectroscopy with a laser-scanning microscope: Exploiting the hidden time structure
    • M.A. Digman, P. Sengupta, P.W. Wiseman, C.M. Brown, A.R. Horwitz, and E. Gratton Fluctuation correlation spectroscopy with a laser-scanning microscope: exploiting the hidden time structure Biophys. J. 88 2005 L33 36
    • (2005) Biophys. J. , vol.88 , pp. 33-36
    • Digman, M.A.1    Sengupta, P.2    Wiseman, P.W.3    Brown, C.M.4    Horwitz, A.R.5    Gratton, E.6
  • 33
    • 38349018672 scopus 로고    scopus 로고
    • The phasor approach to fluorescence lifetime imaging analysis
    • M. Digman, V. Caiolfa, M. Zamai, and E. Gratton The phasor approach to fluorescence lifetime imaging analysis Biophys. J. 94 2008 L14 16
    • (2008) Biophys. J. , vol.94 , pp. 14-16
    • Digman, M.1    Caiolfa, V.2    Zamai, M.3    Gratton, E.4
  • 35
    • 84055200363 scopus 로고    scopus 로고
    • Fluorescence correlation spectroscopy: Past, present, future
    • E.L. Elson Fluorescence correlation spectroscopy: past, present, future Biophys. J. 101 2011 2855 2870
    • (2011) Biophys. J. , vol.101 , pp. 2855-2870
    • Elson, E.L.1
  • 36
    • 66149143136 scopus 로고    scopus 로고
    • Measuring diffusion of lipid-like probes in artificial and natural membranes by raster image correlation spectroscopy (RICS): Use of a commercial laser-scanning microscope with analog detection
    • E. Gielen, N. Smisdom, M. vandeVen, B. De Clercq, E. Gratton, M. Digman, J.M. Rigo, J. Hofkens, Y. Engelborghs, and M. Ameloot Measuring diffusion of lipid-like probes in artificial and natural membranes by raster image correlation spectroscopy (RICS): use of a commercial laser-scanning microscope with analog detection Langmuir 25 2009 5209 5218
    • (2009) Langmuir , vol.25 , pp. 5209-5218
    • Gielen, E.1    Smisdom, N.2    Vandeven, M.3    De Clercq, B.4    Gratton, E.5    Digman, M.6    Rigo, J.M.7    Hofkens, J.8    Engelborghs, Y.9    Ameloot, M.10
  • 37
    • 77954940538 scopus 로고    scopus 로고
    • Two-photon fluorescence correlation microscopy combined with measurements of point spread function; Investigations made in human skin
    • S. Guldbrand, C. Simonsson, M. Goksor, M. Smedh, and M.B. Ericson Two-photon fluorescence correlation microscopy combined with measurements of point spread function; investigations made in human skin Opt. Express 18 2010 15289 15302
    • (2010) Opt. Express , vol.18 , pp. 15289-15302
    • Guldbrand, S.1    Simonsson, C.2    Goksor, M.3    Smedh, M.4    Ericson, M.B.5
  • 38
    • 0036708473 scopus 로고    scopus 로고
    • Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient
    • K.M. Hanson, M.J. Behne, N.P. Barry, T.M. Mauro, E. Gratton, and R.M. Clegg Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient Biophys. J. 83 2002 1682 1690 (Pubitemid 34977738)
    • (2002) Biophysical Journal , vol.83 , Issue.3 , pp. 1682-1690
    • Hanson, K.M.1    Behne, M.J.2    Barry, N.P.3    Mauro, T.M.4    Gratton, E.5    Clegg, R.M.6
  • 39
    • 30944450665 scopus 로고    scopus 로고
    • Deep tissue two-photon microscopy
    • DOI 10.1038/nmeth818, PII N818
    • F. Helmchen, and W. Denk Deep tissue two-photon microscopy Nat. Methods 2 2005 932 940 (Pubitemid 43108729)
    • (2005) Nature Methods , vol.2 , Issue.12 , pp. 932-940
    • Helmchen, F.1    Denk, W.2
  • 40
    • 6344269872 scopus 로고    scopus 로고
    • Quantitative assessment of the transport of elastic and rigid vesicle components and a model drug from these vesicle formulations into human skin in vivo
    • DOI 10.1111/j.0022-202X.2004.23441.x
    • P.L. Honeywell-Nguyen, G.S. Gooris, and J.A. Bouwstra Quantitative assessment of the transport of elastic and rigid vesicle components and a model drug from these vesicle formulations into human skin in vivo J. Invest. Dermatol. 123 2004 902 910 (Pubitemid 39391936)
    • (2004) Journal of Investigative Dermatology , vol.123 , Issue.5 , pp. 902-910
    • Honeywell-Nguyen, P.L.1    Gooris, G.S.2    Bouwstra, J.A.3
  • 41
    • 33748485790 scopus 로고    scopus 로고
    • Elastic vesicles as a tool for dermal and transdermal delivery
    • DOI 10.1080/08982100600848595, PII M54X7GV231G8815N
    • P.L. Honeywell-Nguyen, H.W.W. Groenink, and J.A. Bouwstra Elastic vesicles as a tool for dermal and transdermal delivery J. Liposome Res. 16 2006 273 280 (Pubitemid 44359000)
    • (2006) Journal of Liposome Research , vol.16 , Issue.3 , pp. 273-280
    • Honeywell-Nguyen, P.L.1    Groenink, H.W.W.2    Bouwstra, J.A.3
  • 43
    • 0037279631 scopus 로고    scopus 로고
    • Fluorescence: Basic concepts, practical aspects, and some anecdotes
    • DOI 10.1016/S0076-6879(03)60105-9
    • D.M. Jameson, J.C. Croney, and P.D. Moens Fluorescence: basic concepts, practical aspects, and some anecdotes Methods Enzymol. 360 2003 1 43 (Pubitemid 36207260)
    • (2003) Methods in Enzymology , vol.360 , pp. 1-43
    • Jameson, D.M.1    Croney, J.C.2    Moens, P.D.J.3
  • 44
    • 33750160562 scopus 로고    scopus 로고
    • In vivo assessment of human skin aging by multiphoton laser scanning tomography
    • DOI 10.1364/OL.31.002879
    • M.J. Koehler, K. Konig, P. Elsner, R. Buckle, and M. Kaatz In vivo assessment of human skin aging by multiphoton laser scanning tomography Opt. Lett. 31 2006 2879 2881 (Pubitemid 44600100)
    • (2006) Optics Letters , vol.31 , Issue.19 , pp. 2879-2881
    • Koehler, M.J.1    Konig, K.2    Elsner, P.3    Buckle, R.4    Kaatz, M.5
  • 45
    • 0141644208 scopus 로고    scopus 로고
    • High-resolution multiphoton tomography of human skin with subcellular spatial resolution and picosecond time resolution
    • K. Konig, and I. Riemann High-resolution multiphoton tomography of human skin with subcellular spatial resolution and picosecond time resolution J. Biomed. Opt. 8 2003 432 439
    • (2003) J. Biomed. Opt. , vol.8 , pp. 432-439
    • Konig, K.1    Riemann, I.2
  • 46
    • 33646555074 scopus 로고    scopus 로고
    • In vivo drug screening in human skin using femtosecond laser multiphoton tomography
    • DOI 10.1159/000091974
    • K. Konig, A. Ehlers, F. Stracke, and I. Riemann In vivo drug screening in human skin using femtosecond laser multiphoton tomography Skin Pharmacol. Physiol. 19 2006 78 88 (Pubitemid 43725817)
    • (2006) Skin Pharmacology and Physiology , vol.19 , Issue.2 , pp. 78-88
    • Konig, K.1    Ehlers, A.2    Stracke, F.3    Riemann, I.4
  • 49
    • 79951817544 scopus 로고    scopus 로고
    • Lipid lateral organization on giant unilamellar vesicles containing lipopolysaccharides
    • J. Kubiak, J. Brewer, S. Hansen, and L.A. Bagatolli Lipid lateral organization on giant unilamellar vesicles containing lipopolysaccharides Biophys. J. 100 2011 978 986
    • (2011) Biophys. J. , vol.100 , pp. 978-986
    • Kubiak, J.1    Brewer, J.2    Hansen, S.3    Bagatolli, L.A.4
  • 50
    • 36248953192 scopus 로고    scopus 로고
    • Dual-channel two-photon microscopy study of transdermal transport in skin treated with low-frequency ultrasound and a chemical enhancer
    • DOI 10.1038/sj.jid.5700908, PII 5700908
    • J.T. Kushner, D. Kim, P.T. So, D. Blankschtein, and R.S. Langer Dual-channel two-photon microscopy study of transdermal transport in skin treated with low-frequency ultrasound and a chemical enhancer J. Invest. Dermatol. 127 2007 2832 2846 (Pubitemid 350134811)
    • (2007) Journal of Investigative Dermatology , vol.127 , Issue.12 , pp. 2832-2846
    • Kushner IV, J.1    Kim, D.2    So, P.T.C.3    Blankschtein, D.4    Langer, R.S.5
  • 51
    • 25144479040 scopus 로고    scopus 로고
    • Evaluating cutaneous photoaging by use of multiphoton fluorescence and second-harmonic generation microscopy
    • DOI 10.1364/OL.30.002275
    • S.J. Lin, R. Wu Jr., H.Y. Tan, W. Lo, W.C. Lin, T.H. Young, C.J. Hsu, J.S. Chen, S.H. Jee, and C.Y. Dong Evaluating cutaneous photoaging by use of multiphoton fluorescence and second-harmonic generation microscopy Opt. Lett. 30 2005 2275 2277 (Pubitemid 41345869)
    • (2005) Optics Letters , vol.30 , Issue.17 , pp. 2275-2277
    • Lin, S.-J.1    Wu, R.-J.2    Tan, H.-Y.3    Lo, W.4    Lin, W.-C.5    Young, T.-H.6    Hsu, C.-J.7    Chen, J.-S.8    Jee, S.-H.9    Dong, C.-Y.10
  • 52
    • 0030927012 scopus 로고    scopus 로고
    • Multiphoton excitation fluorescence microscopy and spectroscopy of in vivo human skin
    • B.R. Masters, P.T. So, and E. Gratton Multiphoton excitation fluorescence microscopy and spectroscopy of in vivo human skin Biophys. J. 72 1997 2405 2412 (Pubitemid 27227578)
    • (1997) Biophysical Journal , vol.72 , Issue.6 , pp. 2405-2412
    • Masters, B.R.1    So, P.T.C.2    Gratton, E.3
  • 53
    • 0032498602 scopus 로고    scopus 로고
    • Multiphoton excitation microscopy of in vivo human skin: Functional and morphological optical biopsy based on three-dimensional imaging, lifetime measurements and fluorescence spectroscopy
    • DOI 10.1111/j.1749-6632.1998.tb08187.x
    • B.R. Masters, P.T. So, and E. Gratton Multiphoton excitation microscopy of in vivo human skin. Functional and morphological optical biopsy based on three-dimensional imaging, lifetime measurements and fluorescence spectroscopy Ann. NY Acad. Sci. 838 1998 58 67 (Pubitemid 28127636)
    • (1998) Annals of the New York Academy of Sciences , vol.838 , pp. 58-67
    • Masters, B.R.1    So, P.T.C.2    Gratton, E.3
  • 54
    • 78650661958 scopus 로고    scopus 로고
    • Storage conditions of skin affect tissue structure and subsequent in vitro percutaneous penetration
    • J.B. Nielsen, I. Plasencia, J.A. Sørensen, and L.A. Bagatolli Storage conditions of skin affect tissue structure and subsequent in vitro percutaneous penetration Skin Pharmacol. Physiol. 24 2011 93 102
    • (2011) Skin Pharmacol. Physiol. , vol.24 , pp. 93-102
    • Nielsen, J.B.1    Plasencia, I.2    Sørensen, J.A.3    Bagatolli, L.A.4
  • 55
    • 0022574570 scopus 로고
    • Fluorophores in a polar medium: Time dependence of emission spectra detected by multifrequency phase and modulation fluorometry
    • T. Parasassi, F. Conti, and E. Gratton Fluorophores in a polar medium: time dependence of emission spectra detected by multifrequency phase and modulation fluorometry Cell. Mol. Biol. 32 1986 99 102
    • (1986) Cell. Mol. Biol. , vol.32 , pp. 99-102
    • Parasassi, T.1    Conti, F.2    Gratton, E.3
  • 56
    • 0022647019 scopus 로고
    • Time-resolved fluorescence emission spectra of Laurdan in phospholipid vesicles by multifrequency phase and modulation fluorometry
    • T. Parasassi, F. Conti, and E. Gratton Time-resolved fluorescence emission spectra of LAURDAN in phospholipid vesicles by multifrequency phase and modulation fluorometry Cell. Mol. Biol. 32 1986 103 108 (Pubitemid 16147183)
    • (1986) Cellular and Molecular Biology , vol.32 , Issue.1 , pp. 103-108
    • Parasassi, T.1    Conti, F.2    Gratton, E.3
  • 57
    • 0025295884 scopus 로고
    • Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence
    • T. Parasassi, G. De Stasio, A. d'Ubaldo, and E. Gratton Phase fluctuation in phospholipid membranes revealed by LAURDAN fluorescence Biophys. J. 57 1990 1179 1186 (Pubitemid 20203441)
    • (1990) Biophysical Journal , vol.57 , Issue.6 , pp. 1179-1186
    • Parasassi, T.1    De Stasio, G.2    D'Ubaldo, A.3    Gratton, E.4
  • 58
    • 0025742883 scopus 로고
    • Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of LAURDAN fluorescence
    • T. Parasassi, G. De Stasio, G. Ravagnan, R.M. Rusch, and E. Gratton Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of LAURDAN fluorescence Biophys. J. 60 1991 179 189
    • (1991) Biophys. J. , vol.60 , pp. 179-189
    • Parasassi, T.1    De Stasio, G.2    Ravagnan, G.3    Rusch, R.M.4    Gratton, E.5
  • 59
    • 0030950269 scopus 로고    scopus 로고
    • Two-photon fluorescence microscopy of laurdan generalized polarization domains in model and natural membranes
    • T. Parasassi, E. Gratton, W. Yu, P. Wilson, and M. Levi Two-photon fluorescence microscopy of LAURDAN generalized polarization domains in model and natural membranes Biophys. J. 72 1997 2413 2429 (Pubitemid 27227579)
    • (1997) Biophysical Journal , vol.72 , Issue.6 , pp. 2413-2429
    • Parasassi, T.1    Gratton, E.2    Yu, W.M.3    Wilson, P.4    Levi, M.5
  • 60
    • 36049033182 scopus 로고    scopus 로고
    • Direct visualization of lipid domains in human skin stratum corneum's lipid membranes: Effect of pH and temperature
    • DOI 10.1529/biophysj.106.096164
    • I. Plasencia, L. Norlen, and L.A. Bagatolli Direct visualization of lipid domains in human skin stratum Corneum's lipid membranes: effect of pH and temperature Biophys. J. 93 2007 3142 3155 (Pubitemid 350097105)
    • (2007) Biophysical Journal , vol.93 , Issue.9 , pp. 3142-3155
    • Plasencia, I.1    Norlen, L.2    Bagatolli, L.A.3
  • 61
    • 0020401107 scopus 로고
    • Cytoplasmic pH and free Mg2+ in lymphocytes
    • T.J. Rink, R.Y. Tsien, and T. Pozzan Cytoplasmic pH and free Mg2+ in lymphocytes J. Cell Biol. 95 1982 189 196
    • (1982) J. Cell Biol. , vol.95 , pp. 189-196
    • Rink, T.J.1    Tsien, R.Y.2    Pozzan, T.3
  • 62
    • 84871927564 scopus 로고    scopus 로고
    • Multiphoton laser tomography and fluorescence lifetime imaging of basal cell carcinoma: Morphologic features for non-invasive diagnostics
    • S. Seidenari, F. Arginelli, C. Dunsby, P. French, K. Konig, C. Magnoni, M. Manfredini, C. Talbot, and G. Ponti Multiphoton laser tomography and fluorescence lifetime imaging of basal cell carcinoma: morphologic features for non-invasive diagnostics Exp. Dermatol. 21 2012 831 836
    • (2012) Exp. Dermatol. , vol.21 , pp. 831-836
    • Seidenari, S.1    Arginelli, F.2    Dunsby, C.3    French, P.4    Konig, K.5    Magnoni, C.6    Manfredini, M.7    Talbot, C.8    Ponti, G.9
  • 64
    • 84866061103 scopus 로고    scopus 로고
    • Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH
    • C. Stringari, R.A. Edwards, K.T. Pate, M.L. Waterman, P.J. Donovan, and E. Gratton Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH Sci. Rep. 2 2012 568
    • (2012) Sci. Rep. , vol.2 , pp. 568
    • Stringari, C.1    Edwards, R.A.2    Pate, K.T.3    Waterman, M.L.4    Donovan, P.J.5    Gratton, E.6
  • 65
    • 4544311617 scopus 로고    scopus 로고
    • Multiphoton polarization and generalized polarization microscopy reveal oleic-acid-induced structural changes in intercellular lipid layers of the skin
    • Y. Sun, W. Lo, S.J. Lin, S.H. Jee, and C.Y. Dong Multiphoton polarization and generalized polarization microscopy reveal oleic-acid-induced structural changes in intercellular lipid layers of the skin Opt. Lett. 29 2004 2013 2015
    • (2004) Opt. Lett. , vol.29 , pp. 2013-2015
    • Sun, Y.1    Lo, W.2    Lin, S.J.3    Jee, S.H.4    Dong, C.Y.5
  • 66
    • 33749425694 scopus 로고    scopus 로고
    • Investigating mechanisms of collagen thermal denaturation by high resolution second-harmonic generation imaging
    • DOI 10.1529/biophysj.106.085902
    • Y. Sun, W.L. Chen, S.J. Lin, S.H. Jee, Y.F. Chen, L.C. Lin, P.T. So, and C.Y. Dong Investigating mechanisms of collagen thermal denaturation by high resolution second-harmonic generation imaging Biophys. J. 91 2006 2620 2625 (Pubitemid 44511715)
    • (2006) Biophysical Journal , vol.91 , Issue.7 , pp. 2620-2625
    • Sun, Y.1    Chen, W.-L.2    Lin, S.-J.3    Jee, S.-H.4    Chen, Y.-F.5    Lin, L.-C.6    So, P.T.C.7    Dong, C.-Y.8
  • 68
    • 0032557221 scopus 로고    scopus 로고
    • Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study
    • DOI 10.1016/S0005-2736(97)00273-3, PII S0005273697002733
    • M.E.M.J. van Kuijk-Meuwissen, H.E. Junginger, and J.A. Bouwstra Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study Biochim. Biophys. Acta - Biomembr. 1371 1998 31 39 (Pubitemid 28197051)
    • (1998) Biochimica et Biophysica Acta - Biomembranes , vol.1371 , Issue.1 , pp. 31-39
    • Van Kuijk-Meuwissen, M.E.M.J.1    Junginger, H.E.2    Bouwstra, J.A.3
  • 70
    • 57349126880 scopus 로고    scopus 로고
    • Anisotropic diffusion of fluorescently labeled ATP in rat cardiomyocytes determined by raster image correlation spectroscopy
    • M. Vendelin, and R. Birkedal Anisotropic diffusion of fluorescently labeled ATP in rat cardiomyocytes determined by raster image correlation spectroscopy Am. J. Physiol. Cell Physiol. 295 2008 C1302 1315
    • (2008) Am. J. Physiol. Cell Physiol. , vol.295 , pp. 1302-1315
    • Vendelin, M.1    Birkedal, R.2
  • 72
    • 21244479321 scopus 로고    scopus 로고
    • Interpreting second-harmonic generation images of collagen I fibrils
    • DOI 10.1529/biophysj.104.047308
    • R.M. Williams, W.R. Zipfel, and W.W. Webb Interpreting second-harmonic generation images of collagen I fibrils Biophys. J. 88 2005 1377 1386 (Pubitemid 40975965)
    • (2005) Biophysical Journal , vol.88 , Issue.2 , pp. 1377-1386
    • Williams, R.M.1    Zipfel, W.R.2    Webb, W.W.3
  • 73
    • 78650313673 scopus 로고    scopus 로고
    • Potential of ultraviolet wide-field imaging and multiphoton microscopy for analysis of dehydroergosterol in cellular membranes
    • D. Wustner, J.R. Brewer, L. Bagatolli, and D. Sage Potential of ultraviolet wide-field imaging and multiphoton microscopy for analysis of dehydroergosterol in cellular membranes Microsc. Res. Tech. 74 2011 92 108
    • (2011) Microsc. Res. Tech. , vol.74 , pp. 92-108
    • Wustner, D.1    Brewer, J.R.2    Bagatolli, L.3    Sage, D.4
  • 74
    • 0030048608 scopus 로고    scopus 로고
    • Fluorescence generalized polarization of cell membranes: A two-photon scanning microscopy approach
    • W. Yu, P.T. So, T. French, and E. Gratton Fluorescence generalized polarization of cell membranes: a two-photon scanning microscopy approach Biophys. J. 70 1996 626 636 (Pubitemid 26028279)
    • (1996) Biophysical Journal , vol.70 , Issue.2 , pp. 626-636
    • Yu, W.1    So, P.T.C.2    French, T.3    Gratton, E.4


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