Short KR-12 analogs designed from human cathelicidin LL-37 possessing both antimicrobial and antiendotoxic activities without mammalian cell toxicity

Journal of Peptide Science

Volumn 19, Issue 11, 2013, Pages 700-707

  Jacob, Binu ^a   Park, Il Seon ^a,b   Bang, Jeong Kyu ^c   Shin, Song Yub ^a,b  

^a Chosun University   (South Korea)

^b Chosun University College of Medicine   (South Korea)

^c Korea Basic Science Institute (KBSI)   (South Korea)

Author keywords

Antiendotoxic activity; Antimicrobial activity; Human cathelicidin LL 37; KR 12 analogs

Indexed keywords

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID SEQUENCE; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; CELL SPECIFICITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG MECHANISM; DRUG SYNTHESIS; ERYTHROCYTE; HUMAN; HUMAN CELL; HYDROPHOBICITY; MAMMAL CELL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS EPIDERMIDIS;

MAMMALIA; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

ANTIENDOTOXIC ACTIVITY; ANTIMICROBIAL ACTIVITY; HUMAN CATHELICIDIN LL-37; KR-12 ANALOGS;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; CATHELICIDINS; CELL LINE; ERYTHROCYTES; HEMOLYSIS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPOPOLYSACCHARIDES; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICROBIAL SENSITIVITY TESTS; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885934303     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.2552     Document Type: Article

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