Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants

Biological Psychiatry

Volumn 69, Issue 4, 2011, Pages 360-365

  Malki, Karim ^a   Uher, Rudolf ^a   Paya Cano, Jose ^a   Binder, Elke ^b   Rietschel, Marcella ^c   Zobel, Astrid ^d   Mors, Ole ^e   Hauser, Joanna ^f   Henigsberg, Neven ^g   Jerman, Borut ^h   Souery, Daniel ⁱ   Placentino, Anna ^j   Ng, Mandy Y ^a   Cohen Woods, Sarah ^a   Sluyter, Frans ^a   Farmer, Anne ^a   Aitchison, Katherine J ^a   Craig, Ian W ^a   Lewis, Cathryn M ^a   McGuffin, Peter ^a   Schalkwyk, Leonard C ^a   more..

^a KING'S COLLEGE LONDON   (United Kingdom)

^b INSERM   (France)

^c CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^d UNIVERSITY OF BONN   (Germany)

^e AARHUS UNIVERSITY HOSPITAL   (Denmark)

^f POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^g UNIVERSITY OF ZAGREB   (Croatia)

^h JO EF STEFAN INSTITUTE   (Slovenia)

ⁱ ERASME HOSPITAL   (Belgium)

^j SPEDALI CIVILI   (Italy)

more..

Author keywords

Antidepressants; escitalopram; GENDEP; nortriptyline; pharmacogenetic; PPM1A

Indexed keywords

ESCITALOPRAM; MESSENGER RNA; NORTRIPTYLINE; PHOSPHOPROTEIN PHOSPHATASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; C57BL 10 MOUSE; C57BL 6 MOUSE; CONTROLLED STUDY; DBA MOUSE; DEPRESSION; DRUG RESPONSE; FEMALE; GENE; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; GENOTYPE; HIPPOCAMPUS; HUMAN; INBRED STRAIN; MALE; MOUSE; MULTICENTER STUDY (TOPIC); NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PPM1A GENE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ANIMALS; ANTIDEPRESSIVE AGENTS; CITALOPRAM; DEPRESSIVE DISORDER; FEMALE; GENE EXPRESSION; GENOTYPE; HIPPOCAMPUS; HUMANS; MALE; MICE; MICE, INBRED STRAINS; MIDDLE AGED; NORTRIPTYLINE; PHOSPHOPROTEIN PHOSPHATASES; POLYMORPHISM, GENETIC; RNA, MESSENGER;

EID: 79151479579     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2010.08.011     Document Type: Article

References (34)

1. A. Cipriani, J.R. Geddes, T.A. Furukawa, and C. Barbui Metareview on short-term effectiveness and safety of antidepressants for depression: An evidence-based approach to inform clinical practice Can J Psychiatry 52 2007 553 562
2. H.G. Ruhe, J. Huyser, J.A. Swinkels, and A.H. Schene Switching antidepressants after a first selective serotonin reuptake inhibitor in major depressive disorder: A systematic review J Clin Psychiatry 67 2006 1836 1855
3. A.J. Rush, M.H. Trivedi, S.R. Wisniewski, A.A. Nierenberg, J.W. Stewart, and D. Warden Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR (*)D report Am J Psychiatry 163 2006 1905 1917
4. M.E. Thase, A.R. Entsuah, and R.L. Rudolph Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors Br J Psychiatry 178 2001 234 241
5. M.H. Trivedi, A.J. Rush, S.R. Wisniewski, A.A. Nierenberg, D. Warden, and L. Ritz Evaluation of outcomes with citalopram for depression using measurement-based care in STAR (*)D: implications for clinical practice Am J Psychiatry 163 2006 28 40
6. A.A. Nierenberg Predictors of response to antidepressants general principles clinical implications Psychiatr Clin North Am 26 2003 345 352 viii
7. J. Kirchheiner, K. Nickchen, M. Bauer, M.L. Wong, J. Licinio, I. Roots, and J. Brockmller Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response Mol Psychiatry 9 2004 442 473
8. R. Uher, P. Huezo-Diaz, N. Perroud, R. Smith, M. Rietschel, and O. Mors Genetic predictors of response to antidepressants in the GENDEP project Pharmacogenomics J 9 2009 225 233
9. M. Kato, and A. Serretti Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder Mol Psychiatry 15 2008 473 500
10. F.J. McMahon, S. Buervenich, D. Charney, R. Lipsky, A.J. Rush, and A.F. Wilson Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment Am J Hum Genet 78 2006 804 814
11. M. Ising, S. Lucae, E.B. Binder, T. Bettecken, M. Uhr, and S. Ripke A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression Arch Gen Psychiatry 66 2009 966 975
12. H.A. Garriock, and S.P. Hamilton Genetic studies of drug response and side effects in the STAR (*)D study, part 2 J Clin Psychiatry 70 2009 1323 1325
13. H.A. Garriock, and S.P. Hamilton Genetic studies of drug response and side effects in the STAR (*)D study, part 1 J Clin Psychiatry 70 2009 1186 1187
14. R. Uher, N. Perroud, M.Y. Ng, J. Hauser, N. Henigsberg, and W. Maier Genome-wide pharmacogenetics of antidepressant response in the GENDEP project Am J Psychiatry 167 2010 555 564
15. R. Uher, W. Maier, J. Hauser, A. Marusic, C. Schmael, and O. Mors Differential efficacy of escitalopram and nortriptyline on dimensional measures of depression Br J Psychiatry 194 2009 252 259
16. C. Sanchez, P.B. Bergqvist, L.T. Brennum, S. Gupta, S. Hogg, A. Larsen, and O. Wiborg Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities Psychopharmacology 167 2003 353 362
17. C. Sanchez, and J. Hyttel Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding Cell Mol Neurobiol 19 1999 467 489
18. J.K. Wing, and T.B. stn SN Diagnosis and Clinical Measurement in Psychiatry A Reference Manual for SCAN 1998 Cambridge University Press Cambridge
19. S.A. Montgomery, and M. sberg A new depression scale designed to be sensitive to change Br J Psychiatry 134 1979 382 389
20. K.A. Frazer, D.G. Ballinger, D.R. Cox, D.A. Hinds, L.L. Stuve, and R.A. Gibbs A second generation human haplotype map of over 3.1 million SNPs Nature 449 2007 851 861
21. R.A. Irizarry, B. Hobbs, F. Collin, Y.D. Beazer-Barclay, K.J. Antonellis, U. Scherf, and T.P. Speed Exploration, normalization, and summaries of high density oligonucleotide array probe level data Biostatistics 4 2003 249 264
22. S. Purcell, B. Neale, K. Todd-Brown, L. Thomas, M.A. Ferreira, and D. Bender PLINK: A tool set for whole-genome association and population-based linkage analyses Am J Hum Genet 81 2007 559 575
23. J. Li, and L. Ji Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix Heredity 95 2005 221 227
24. J.D. Storey, and R. Tibshirani Statistical significance for genomewide studies Proc Natl Acad Sci U S A 100 2003 9440 9445
25. B.L. Browning, and S.R. Browning Efficient multilocus association testing for whole genome association studies using localized haplotype clustering Genet Epidemiol 31 2007 365 375
26. W. Sun, Y. Yu, G. Dotti, T. Shen, X. Tan, and B. Savoldo PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation Cell Signal 21 2009 95 102
27. D. Cohen, and A. Musch Apical surface formation in MDCK cells: Regulation by the serine/threonine kinase EMK1 Methods 30 2003 269 276
28. J.J. Ventura, S. Tenbaum, E. Perdiguero, M. Huth, C. Guerra, and M. Barbacid p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation Nat Genet 39 2007 750 758
29. S.K. Mann, W.M. Yonemoto, S.S. Taylor, and R.A. Firtel DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase Proc Natl Acad Sci U S A 89 1992 10701 10705
30. A.G. Moll, M.T. Lindenmeyer, M. Kretzler, P.J. Nelson, R. Zimmer, and C.D. Cohen Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays PLoS ONE 4 2009 e4702
31. J.P. Liuzzi, F. Aydemir, H. Nam, M.D. Knutson, and R.J. Cousins Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells Proc Natl Acad Sci U S A 103 2006 13612 13617
32. M. Maes, P.C. D'Haese, S. Scharpe, P. D'Hondt, P. Cosyns, and M.E. De Broe Hypozincemia in depression J Affect Disord 31 1994 135 140
33. I.J. McLoughlin, and J.S. Hodge Zinc in depressive disorder Acta Psychiatr Scand 82 1990 451 453
34. G. Nowak, and M. Schlegel-Zawadzka Alterations in serum and brain trace element levels after antidepressant treatment, part I Zinc Biol Trace Elem Res 67 1999 85 92