The PARK2 gene is involved in the maintenance of pancreatic β-cell functions related to insulin production and secretion

Molecular and Cellular Endocrinology

Volumn 382, Issue 1, 2014, Pages 178-189

  Jin, Hyun Seok ^a   Kim, Jeonghyun ^a   Lee, Soo Jin ^a   Kim, Kyunga ^b   Go, Min Jin ^c   Lee, Jong Young ^c   Lee, Hye Ja ^c   Song, Jihyun ^c   Jeon, Byeong Tak ^d   Roh, Gu Seob ^d   Kim, Sung Jun ^e   Kim, Bo Young ^a   Hong, Kyung Won ^f   Yoo, Young Hyun ^g   Oh, Beomseok ^h   Kang, Yup ^a   Jeong, Seon Yong ^a  

^a Ajou University School of Medicine   (South Korea)

^b Sookmyung Women's University   (South Korea)

^c Korea National Institute of Health   (South Korea)

^d Gyeongsang National University School of Medicine   (South Korea)

^e CJ Corporation   (South Korea)

^f Korea Centres for Disease Control and Prevention   (South Korea)

^g Dong A University   (South Korea)

^h Kyung Hee University Hospital   (South Korea)

Author keywords

Genetic association; Insulin secretion; Mitochondria; Pancreatic cell; PARK2; Type 2 diabetes

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; INSULIN; PARKIN; REACTIVE OXYGEN METABOLITE;

ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHILD; COHORT ANALYSIS; DOWN REGULATION; FEMALE; GENE; GENE CONTROL; GENE EXPRESSION; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN RELEASE; INSULIN SYNTHESIS; KOREA; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PARK2 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM;

GENETIC ASSOCIATION; INSULIN SECRETION; MITOCHONDRIA; PANCREATIC Β-CELL; PARK2; TYPE 2 DIABETES;

ADENOSINE TRIPHOSPHATE; ADULT; AGED; ANIMALS; COHORT STUDIES; GENE EXPRESSION PROFILING; GENE KNOCKDOWN TECHNIQUES; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; MITOCHONDRIA; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT, HERITABLE; RATS; UBIQUITIN-PROTEIN LIGASES;

EID: 84885817939     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.09.031     Document Type: Article

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