-
1
-
-
39749182247
-
Antibody diversification by somatic mutation: from Burnet onwards
-
Neuberger, M. S., Antibody diversification by somatic mutation: from Burnet onwards. Immunol. Cell Biol. 2008. 86: 124-132.
-
(2008)
Immunol. Cell Biol.
, vol.86
, pp. 124-132
-
-
Neuberger, M.S.1
-
2
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu, M., Kinoshita, K., Fagarasan, S., Yamada, S., Shinkai, Y., and Honjo, T., Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 2000. 102: 553-563.
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
3
-
-
34249790004
-
Molecular mechanisms of antibody somatic hypermutation
-
Di Noia, J. M. and Neuberger, M. S., Molecular mechanisms of antibody somatic hypermutation. Annu. Rev. Biochem. 2007. 76: 1-22.
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 1-22
-
-
Di Noia, J.M.1
Neuberger, M.S.2
-
4
-
-
0032127804
-
Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting
-
Rada, C., Ehrenstein, M. R., Neuberger, M. S. and Milstein, C., Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting. Immunity 1998. 9: 135-141.
-
(1998)
Immunity
, vol.9
, pp. 135-141
-
-
Rada, C.1
Ehrenstein, M.R.2
Neuberger, M.S.3
Milstein, C.4
-
5
-
-
0034614916
-
Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern
-
Wiesendanger, M., Kneitz, B., Edelmann, W. and Scharff, M. D., Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern. J. Exp. Med. 2000. 191: 579-584.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 579-584
-
-
Wiesendanger, M.1
Kneitz, B.2
Edelmann, W.3
Scharff, M.D.4
-
6
-
-
1142299546
-
Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice
-
Bardwell, P. D., Woo, C. J., Wei, K., Li, Z., Martin, A., Sack, S. Z., Parris, T. et al., Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice. Nat. Immunol. 2004. 5: 224-229.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 224-229
-
-
Bardwell, P.D.1
Woo, C.J.2
Wei, K.3
Li, Z.4
Martin, A.5
Sack, S.Z.6
Parris, T.7
-
7
-
-
0035377269
-
DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes
-
Zeng, X., Winter, D. B., Kasmer, C., Kraemer, K. H., Lehmann, A. R. and Gearhart, P. J., DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes. Nat. Immunol. 2001. 2: 537-541.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 537-541
-
-
Zeng, X.1
Winter, D.B.2
Kasmer, C.3
Kraemer, K.H.4
Lehmann, A.R.5
Gearhart, P.J.6
-
8
-
-
18244401095
-
Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse
-
Delbos, F., De, S. A., Faili, A., Aoufouchi, S., Weill, J. C. and Reynaud, C. A., Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse. J. Exp. Med. 2005. 201: 1191-1196.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1191-1196
-
-
Delbos, F.1
De, S.A.2
Faili, A.3
Aoufouchi, S.4
Weill, J.C.5
Reynaud, C.A.6
-
9
-
-
20844452399
-
Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification
-
Martomo, S. A., Yang, W. W., Wersto, R. P., Ohkumo, T., Kondo, Y., Yokoi, M., Masutani, C. et al, Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification. Proc. Natl. Acad. Sci. USA 2005. 102: 8656-8661.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 8656-8661
-
-
Martomo, S.A.1
Yang, W.W.2
Wersto, R.P.3
Ohkumo, T.4
Kondo, Y.5
Yokoi, M.6
Masutani, C.7
-
10
-
-
33846404877
-
DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse
-
Delbos, F., Aoufouchi, S., Faili, A., Weill, J. C. and Reynaud, C. A., DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse. J. Exp. Med. 2007. 204: 17-23.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 17-23
-
-
Delbos, F.1
Aoufouchi, S.2
Faili, A.3
Weill, J.C.4
Reynaud, C.A.5
-
11
-
-
76149097802
-
A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta
-
Faili, A., Stary, A., Delbos, F., Weller, S., Aoufouchi, S., Sarasin, A., Weill, J. C. et al., A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta. J. Immunol. 2009. 182: 6353-6359.
-
(2009)
J. Immunol.
, vol.182
, pp. 6353-6359
-
-
Faili, A.1
Stary, A.2
Delbos, F.3
Weller, S.4
Aoufouchi, S.5
Sarasin, A.6
Weill, J.C.7
-
12
-
-
73349091865
-
Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation
-
Krijger, P. H., Langerak, P., van den Berk, P. C. and Jacobs, H., Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation. J. Exp. Med. 2009. 206: 2603-2611.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2603-2611
-
-
Krijger, P.H.1
Langerak, P.2
van den Berk, P.C.3
Jacobs, H.4
-
13
-
-
34547797940
-
A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification
-
Langerak, P., Nygren, A. O., Krijger, P. H., van den Berk, P. C. and Jacobs, H., A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification. J. Exp. Med. 2007. 204: 1989-1998.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1989-1998
-
-
Langerak, P.1
Nygren, A.O.2
Krijger, P.H.3
van den Berk, P.C.4
Jacobs, H.5
-
14
-
-
55849092898
-
Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression
-
Roa, S., Avdievich, E., Peled, J. U., MacCarthy, T., Werling, U., Kuang, F. L., Kan, R. et al., Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression. Proc. Natl. Acad. Sci. USA 2008. 105: 16248-16253.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 16248-16253
-
-
Roa, S.1
Avdievich, E.2
Peled, J.U.3
MacCarthy, T.4
Werling, U.5
Kuang, F.L.6
Kan, R.7
-
15
-
-
80053322944
-
PCNA ubiquitination-independent activation of polymerase eta during somatic hypermutation and DNA damage tolerance
-
Krijger, P. H., van den Berk, P. C., Wit, N., Langerak, P., Jansen, J. G., Reynaud, C. A., de, W. N. et al., PCNA ubiquitination-independent activation of polymerase eta during somatic hypermutation and DNA damage tolerance. DNA Repair (Amst.) 2011. 10: 1051-1059.
-
(2011)
DNA Repair (Amst.)
, vol.10
, pp. 1051-1059
-
-
Krijger, P.H.1
van den Berk, P.C.2
Wit, N.3
Langerak, P.4
Jansen, J.G.5
Reynaud, C.A.6
de, W.N.7
-
16
-
-
0037108463
-
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
-
Rada, C., Williams, G. T., Nilsen, H., Barnes, D. E., Lindahl, T. and Neuberger, M. S., Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr. Biol. 2002. 12: 1748-1755.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1748-1755
-
-
Rada, C.1
Williams, G.T.2
Nilsen, H.3
Barnes, D.E.4
Lindahl, T.5
Neuberger, M.S.6
-
17
-
-
33344468484
-
Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice
-
Jansen, J. G., Langerak, P., Tsaalbi-Shtylik, A., van den, B. P., Jacobs, H. and de Wind, N., Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice. J. Exp. Med. 2006. 203: 319-323.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 319-323
-
-
Jansen, J.G.1
Langerak, P.2
Tsaalbi-Shtylik, A.3
van den, B.P.4
Jacobs, H.5
de Wind, N.6
-
18
-
-
33644543730
-
The catalytic activity of REV1 is employed during immunoglobulin gene diversification in DT40
-
Ross, A. L. and Sale, J. E., The catalytic activity of REV1 is employed during immunoglobulin gene diversification in DT40. Mol. Immunol. 2006. 43: 1587-1594.
-
(2006)
Mol. Immunol.
, vol.43
, pp. 1587-1594
-
-
Ross, A.L.1
Sale, J.E.2
-
19
-
-
68149178379
-
A critical role for REV1 in regulating the induction of C:G transitions and A:T mutations during Ig gene hypermutation
-
Masuda, K., Ouchida, R., Li, Y., Gao, X., Mori, H. and Wang, J. Y., A critical role for REV1 in regulating the induction of C:G transitions and A:T mutations during Ig gene hypermutation. J. Immunol 2009. 183: 1846-1850.
-
(2009)
J. Immunol
, vol.183
, pp. 1846-1850
-
-
Masuda, K.1
Ouchida, R.2
Li, Y.3
Gao, X.4
Mori, H.5
Wang, J.Y.6
-
20
-
-
33751050806
-
A role for PCNA ubiquitination in immunoglobulin hypermutation
-
Arakawa, H., Moldovan, G. L., Saribasak, H., Saribasak, N. N., Jentsch, S. and Buerstedde, J. M., A role for PCNA ubiquitination in immunoglobulin hypermutation. PLoS Biol. 2006. 4: e366.
-
(2006)
PLoS Biol.
, vol.4
-
-
Arakawa, H.1
Moldovan, G.L.2
Saribasak, H.3
Saribasak, N.N.4
Jentsch, S.5
Buerstedde, J.M.6
-
21
-
-
84863233870
-
Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to G and G to C transversions during Ig gene hypermutation
-
Kano, C., Hanaoka, F. and Wang, J. Y., Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to G and G to C transversions during Ig gene hypermutation. Int. Immunol. 2012. 24: 169-174.
-
(2012)
Int. Immunol.
, vol.24
, pp. 169-174
-
-
Kano, C.1
Hanaoka, F.2
Wang, J.Y.3
-
22
-
-
0029787108
-
Deoxycytidyl transferase activity of yeast REV1 protein
-
Nelson, J. R., Lawrence, C. W. and Hinkle, D. C., Deoxycytidyl transferase activity of yeast REV1 protein. Nature 1996. 382: 729-731.
-
(1996)
Nature
, vol.382
, pp. 729-731
-
-
Nelson, J.R.1
Lawrence, C.W.2
Hinkle, D.C.3
-
23
-
-
6344256944
-
Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation
-
Rada, C., Di Noia, J. M. and Neuberger, M. S., Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation. Mol. Cell 2004. 16: 163-171.
-
(2004)
Mol. Cell
, vol.16
, pp. 163-171
-
-
Rada, C.1
Di Noia, J.M.2
Neuberger, M.S.3
-
24
-
-
33749519393
-
Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice
-
Shen, H. M., Tanaka, A., Bozek, G., Nicolae, D. and Storb, U., Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice. J. Immunol. 2006. 177: 5386-5392.
-
(2006)
J. Immunol.
, vol.177
, pp. 5386-5392
-
-
Shen, H.M.1
Tanaka, A.2
Bozek, G.3
Nicolae, D.4
Storb, U.5
-
25
-
-
70249093627
-
The concerted action of Msh2 and UNG stimulates somatic hypermutation at A T base pairs
-
Frieder, D., Larijani, M., Collins, C., Shulman, M. and Martin, A., The concerted action of Msh2 and UNG stimulates somatic hypermutation at A T base pairs. Mol. Cell Biol. 2009. 29: 5148-5157.
-
(2009)
Mol. Cell Biol.
, vol.29
, pp. 5148-5157
-
-
Frieder, D.1
Larijani, M.2
Collins, C.3
Shulman, M.4
Martin, A.5
-
26
-
-
84870427871
-
Rev1 recruits Ung to switch regions and enhances dU glycosylation for immunoglobulin class switch DNA recombination
-
Zan, H., White, C. A., Thomas, L. M., Mai, T., Li, G., Xu, Z., Zhang, J. et al., Rev1 recruits Ung to switch regions and enhances dU glycosylation for immunoglobulin class switch DNA recombination. Cell Rep. 2012. 2: 1220-1232.
-
(2012)
Cell Rep.
, vol.2
, pp. 1220-1232
-
-
Zan, H.1
White, C.A.2
Thomas, L.M.3
Mai, T.4
Li, G.5
Xu, Z.6
Zhang, J.7
-
27
-
-
0033804719
-
Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity
-
Smits, R., Hofland, N., Edelmann, W., Geugien, M., Jagmohan-Changur, S., Albuquerque, C., Breukel, C. et al., Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity. Genes Chromosomes Cancer 2000. 29: 229-239.
-
(2000)
Genes Chromosomes Cancer
, vol.29
, pp. 229-239
-
-
Smits, R.1
Hofland, N.2
Edelmann, W.3
Geugien, M.4
Jagmohan-Changur, S.5
Albuquerque, C.6
Breukel, C.7
-
28
-
-
0030845386
-
Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice
-
Jolly, C. J., Klix, N. and Neuberger, M. S., Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice. Nucleic Acids Res. 1997. 25: 1913-1919.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 1913-1919
-
-
Jolly, C.J.1
Klix, N.2
Neuberger, M.S.3
|