메뉴 건너뛰기




Volumn 86, Issue 8, 2013, Pages 1105-1113

Genetic matters: Thirty years of progress using mouse models in nicotinic research

Author keywords

Knockout mice; Mouse genetics; Mutations; Nicotine; Nicotinic acetylcholine receptors

Indexed keywords


EID: 84885646416     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.05.021     Document Type: Review
Times cited : (11)

References (100)
  • 1
    • 0001555094 scopus 로고
    • Cancer and smoking
    • Fisher RA. Cancer and smoking. Nature 1958;182:596.
    • (1958) Nature , vol.182 , pp. 596
    • Fisher, R.A.1
  • 2
    • 54949105395 scopus 로고    scopus 로고
    • Molecular genetics of addiction and related heritable phenotypes: Genome-wide association approaches identify connectivity constellation and drug target genes with pleiotropic effects
    • Uhl GR, Drgon T, Johnson C, Li CY, Contoreggi C, Hess J, et al. Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify connectivity constellation and drug target genes with pleiotropic effects. Ann N Y Acad Sci 2008;1141:318-81.
    • (2008) Ann N Y Acad Sci , vol.1141 , pp. 318-381
    • Uhl, G.R.1    Drgon, T.2    Johnson, C.3    Li, C.Y.4    Contoreggi, C.5    Hess, J.6
  • 3
    • 84862703991 scopus 로고    scopus 로고
    • The interplay of genes and adolescent development in substance use disorders: Leveraging findings from gwas meta-Analyses to test developmental hypotheses about nicotine consumption
    • Vrieze SI, McGue M, Iacono WG. The interplay of genes and adolescent development in substance use disorders: leveraging findings from GWAS meta-Analyses to test developmental hypotheses about nicotine consumption. Hum Genet 2012;131:791-801.
    • (2012) Hum Genet , vol.131 , pp. 791-801
    • Vrieze, S.I.1    McGue, M.2    Iacono, W.G.3
  • 5
    • 0037764979 scopus 로고    scopus 로고
    • Genetics of alcohol and tobacco use in humans
    • DOI 10.1080/07853890310010014
    • Tyndale RF. Genetics of alcohol and tobacco use in humans. Ann Med 2003;35:94-121. (Pubitemid 36638212)
    • (2003) Annals of Medicine , vol.35 , Issue.2 , pp. 94-121
    • Tyndale, R.F.1
  • 6
    • 0037221274 scopus 로고    scopus 로고
    • A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins
    • DOI 10.1046/j.1360-0443.2003.00295.x
    • Li MD, Cheng R, Ma JZ, Swan GE. A meta-Analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction 2003;98:23-31. (Pubitemid 36044333)
    • (2003) Addiction , vol.98 , Issue.1 , pp. 23-31
    • Li, M.D.1    Cheng, R.2    Ma, J.Z.3    Swan, G.E.4
  • 11
    • 17144413330 scopus 로고
    • Abnormal avoidance learning in mice lacking functional high-Affinity nicotine receptor in the brain
    • Picciotto MR, Zoli M, Lena C, Bessis A, Lallemand Y, Le Novere N, et al. Abnormal avoidance learning in mice lacking functional high-Affinity nicotine receptor in the brain. Nature 1995;374:65-7.
    • (1995) Nature , vol.374 , pp. 65-67
    • Picciotto, M.R.1    Zoli, M.2    Lena, C.3    Bessis, A.4    Lallemand, Y.5    Le Novere, N.6
  • 16
    • 80052027888 scopus 로고    scopus 로고
    • Recent advances in genemanipulation and nicotinic acetylcholine receptor biology
    • TammimakiA,HortonWJ, Stitzel JA. Recent advances in genemanipulation and nicotinic acetylcholine receptor biology. BiochemPharmacol 2011;82:808-19.
    • (2011) BiochemPharmacol , vol.82 , pp. 808-819
    • Tammimaki, A.1    Horton, W.J.2    Stitzel, J.A.3
  • 17
    • 1642347644 scopus 로고    scopus 로고
    • Null mutant analysis of responses to nicotine: Deletion of beta2 nicotinic acetylcholine receptor subunit but not alpha7 subunit reduces sensitivity to nicotine-induced locomotor depression and hypothermia
    • Tritto T, McCallum SE, Waddle SA, Hutton SR, Paylor R, Collins AC, et al. Null mutant analysis of responses to nicotine: deletion of beta2 nicotinic acetylcholine receptor subunit but not alpha7 subunit reduces sensitivity to nicotine-induced locomotor depression and hypothermia. Nicotine Tob Res 2004;6:145-58.
    • (2004) Nicotine Tob Res , vol.6 , pp. 145-158
    • Tritto, T.1    McCallum, S.E.2    Waddle, S.A.3    Hutton, S.R.4    Paylor, R.5    Collins, A.C.6
  • 18
    • 84869139440 scopus 로고    scopus 로고
    • Mice expressing the adnfle valine 287 leucine mutation of the beta2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function
    • O'Neill HC, Laverty DC, Patzlaff NE, Cohen BN, Fonck C, McKinney S, et al. Mice expressing the ADNFLE valine 287 leucine mutation of the Beta2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function. Pharmacol Biochem Behav 2013;103:603-21.
    • (2013) Pharmacol Biochem Behav , vol.103 , pp. 603-621
    • O'Neill, H.C.1    Laverty, D.C.2    Patzlaff, N.E.3    Cohen, B.N.4    Fonck, C.5    McKinney, S.6
  • 19
    • 0036076383 scopus 로고    scopus 로고
    • A polymorphism in the mouse neuronal α4 nicotinic receptor subunit results in an alteration in receptor function
    • DOI 10.1124/mol.62.2.334
    • Dobelis P, Marks MJ, Whiteaker P, Balogh SA, Collins AC, Stitzel JA. A polymorphism in the mouse neuronal alpha4 nicotinic receptor subunit results in an alteration in receptor function. Mol Pharmacol 2002;62:334-42. (Pubitemid 34804114)
    • (2002) Molecular Pharmacology , vol.62 , Issue.2 , pp. 334-342
    • Dobelis, P.1    Marks, M.J.2    Whiteaker, P.3    Balogh, S.A.4    Collins, A.C.5    Stitzel, J.A.6
  • 20
    • 0023629856 scopus 로고
    • Nicotine response and nicotinic receptors in long-sleep and short-sleep mice
    • DOI 10.1016/0741-8329(87)90092-9
    • De Fiebre CM, Medhurst LJ, Collins AC. Nicotine response and nicotinic receptors in long-sleep and short-sleep mice. Alcohol 1987;4:493-501. (Pubitemid 17163843)
    • (1987) Alcohol , vol.4 , Issue.6 , pp. 493-501
    • De Fiebre, C.M.1    Medhurst, L.J.2    Collins, A.C.3
  • 21
    • 0036260197 scopus 로고    scopus 로고
    • 6 nicotinic receptor genes
    • DOI 10.1097/00008571-200204000-00004
    • Tritto T, Stitzel JA, Marks MJ, Romm E, Collins AC. Variability in response to nicotine in the LSxSS RI strains: potential role of polymorphisms in alpha4 and alpha6 nicotinic receptor genes. Pharmacogenetics 2002;12:197-208. (Pubitemid 34596784)
    • (2002) Pharmacogenetics , vol.12 , Issue.3 , pp. 197-208
    • Tritto, T.1    Stitzel, J.A.2    Marks, M.J.3    Romm, E.4    Collins, A.C.5
  • 22
    • 0037289747 scopus 로고    scopus 로고
    • Alternate stoichiometries of α4β2 nicotinic acetylcholine receptors
    • DOI 10.1124/mol.63.2.332
    • Nelson ME, Kuryatov A, Choi CH, Zhou Y, Lindstrom J. Alternate stoichiometries of alpha4beta2 nicotinic acetylcholine receptors. Mol Pharmacol 2003;63:332-41. (Pubitemid 36158368)
    • (2003) Molecular Pharmacology , vol.63 , Issue.2 , pp. 332-341
    • Nelson, M.E.1    Kuryatov, A.2    Choi, C.H.3    Zhou, Y.4    Lindstrom, J.5
  • 24
    • 0032426910 scopus 로고    scopus 로고
    • Four pharmacologically distinct subtypes of α4β2 nicotinic acetylcholine receptor expressed in Xenopus laevis oocytes
    • Zwart R, Vijverberg HP. Four pharmacologically distinct subtypes of alpha4-beta2 nicotinic acetylcholine receptor expressed in Xenopus laevis oocytes. Mol Pharmacol 1998;54:1124-31. (Pubitemid 29002058)
    • (1998) Molecular Pharmacology , vol.54 , Issue.6 , pp. 1124-1131
    • Zwart, R.1    Vijverberg, H.P.M.2
  • 25
    • 33746238089 scopus 로고    scopus 로고
    • α4β2 nicotinic receptors with high and low acetylcholine sensitivity: Pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine
    • DOI 10.1124/mol.106.023044
    • Moroni M, Zwart R, Sher E, Cassels BK, Bermudez I. alpha4beta2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-Term exposure to nicotine. Mol Pharmacol 2006;70:755-68. (Pubitemid 44092336)
    • (2006) Molecular Pharmacology , vol.70 , Issue.2 , pp. 755-768
    • Moroni, M.1    Zwart, R.2    Sher, E.3    Cassels, B.K.4    Bermudez, I.5
  • 27
    • 44249097518 scopus 로고    scopus 로고
    • + efflux in cortex and thalamus and alters relative expression of α4 and β2 subunits
    • DOI 10.1124/mol.108.045203
    • Gotti C, Moretti M, Meinerz NM, Clementi F, Gaimarri A, Collins AC, et al. Partial deletion of the nicotinic cholinergic receptor alpha 4 or beta 2 subunit genes changes the acetylcholine sensitivity of receptor-mediated 86Rb+ efflux in cortex and thalamus and alters relative expression of alpha 4 and beta 2 subunits. Mol Pharmacol 2008;73:1796-807. (Pubitemid 351724367)
    • (2008) Molecular Pharmacology , vol.73 , Issue.6 , pp. 1796-1807
    • Gotti, C.1    Moretti, M.2    Meinerz, N.M.3    Clementi, F.4    Gaimarri, A.5    Collins, A.C.6    Marks, M.J.7
  • 28
    • 0038642646 scopus 로고    scopus 로고
    • The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity α4β2 nAChRs
    • DOI 10.1016/S0028-3908(03)00167-9
    • Kim H, Flanagin BA, Qin C, Macdonald RL, Stitzel JA. The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs. Neuropharmacology 2003;45:345-54. (Pubitemid 36836131)
    • (2003) Neuropharmacology , vol.45 , Issue.3 , pp. 345-354
    • Kim, H.1    Flanagin, B.A.2    Qin, C.3    Macdonald, R.L.4    Stitzel, J.A.5
  • 29
    • 33745280117 scopus 로고    scopus 로고
    • Untranslated region-dependent exclusive expression of high-sensitivity subforms of alpha4beta2 and alpha3beta2 nicotinic acetylcholine receptors
    • Briggs CA, Gubbins EJ, Marks MJ, Putman CB, Thimmapaya R, Meyer MD, et al. Untranslated region-dependent exclusive expression of high-sensitivity subforms of alpha4beta2 and alpha3beta2 nicotinic acetylcholine receptors. Mol Pharmacol 2006;70:227-40.
    • (2006) Mol Pharmacol , vol.70 , pp. 227-240
    • Briggs, C.A.1    Gubbins, E.J.2    Marks, M.J.3    Putman, C.B.4    Thimmapaya, R.5    Meyer, M.D.6
  • 33
    • 45749094140 scopus 로고    scopus 로고
    • Roles of accessory subunits in α4β2 nicotinic receptors
    • DOI 10.1124/mol.108.046789
    • Kuryatov A, Onksen J, Lindstrom J. Roles of accessory subunits in alpha4-beta2(*) nicotinic receptors. Mol Pharmacol 2008;74:132-43. (Pubitemid 351872165)
    • (2008) Molecular Pharmacology , vol.74 , Issue.1 , pp. 132-143
    • Kuryatov, A.1    Onksen, J.2    Lindstrom, J.3
  • 34
    • 77953738220 scopus 로고    scopus 로고
    • Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice
    • Jackson KJ, Marks MJ, Vann RE, Chen X, Gamage TF, Warner JA, et al. Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice. J Pharmacol Exp Ther 2010;334:137-46.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 137-146
    • Jackson, K.J.1    Marks, M.J.2    Vann, R.E.3    Chen, X.4    Gamage, T.F.5    Warner, J.A.6
  • 35
    • 0034280436 scopus 로고    scopus 로고
    • Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse
    • Ross SA, Wong JY, Clifford JJ, Kinsella A, Massalas JS, Horne MK, et al. Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse. J Neurosci 2000;20:6431-41.
    • (2000) J Neurosci , vol.20 , pp. 6431-6441
    • Ross, S.A.1    Wong, J.Y.2    Clifford, J.J.3    Kinsella, A.4    Massalas, J.S.5    Horne, M.K.6
  • 36
    • 79960001779 scopus 로고    scopus 로고
    • Intravenous nicotine self-Administration and cueinduced reinstatement in mice: Effects of nicotine dose, rate of drug infusion and prior instrumental training
    • Fowler CD, Kenny PJ. Intravenous nicotine self-Administration and cueinduced reinstatement in mice: effects of nicotine dose, rate of drug infusion and prior instrumental training. Neuropharmacology 2011;61:687-98.
    • (2011) Neuropharmacology , vol.61 , pp. 687-698
    • Fowler, C.D.1    Kenny, P.J.2
  • 37
    • 0029993434 scopus 로고    scopus 로고
    • Inbred mouse strains vary in oral self-selection of nicotine
    • DOI 10.1007/BF02247438
    • Robinson SF, Marks MJ, Collins AC. Inbred mouse strains vary in oral selfselection of nicotine. Psychopharmacology (Berl) 1996;124:332-9. (Pubitemid 26147147)
    • (1996) Psychopharmacology , vol.124 , Issue.4 , pp. 332-339
    • Robinson, S.F.1    Marks, M.J.2    Collins, A.C.3
  • 38
    • 0024350215 scopus 로고
    • Strain comparison of nicotine-induced seizure sensitivity and nicotinic receptors
    • Miner LL, Collins AC. Strain comparison of nicotine-induced seizure sensitivity and nicotinic receptors. Pharmacol Biochem Behav 1989;33:469-75. (Pubitemid 19245538)
    • (1989) Pharmacology Biochemistry and Behavior , vol.33 , Issue.2 , pp. 469-475
    • Miner, L.L.1    Collins, A.C.2
  • 39
    • 68749097207 scopus 로고    scopus 로고
    • Characterization of pharmacological and behavioral differences to nicotine in c57bl/6 and dba/2 mice
    • Jackson KJ, Walters CL, Miles MF, Martin BR, Damaj MI. Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice. Neuropharmacology 2009;57:347-55.
    • (2009) Neuropharmacology , vol.57 , pp. 347-355
    • Jackson, K.J.1    Walters, C.L.2    Miles, M.F.3    Martin, B.R.4    Damaj, M.I.5
  • 40
    • 32844457924 scopus 로고    scopus 로고
    • The β2 but not α7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice
    • DOI 10.1007/s00213-005-0295-x
    • Walters CL, Brown S, Changeux JP, Martin B, Damaj MI. The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice. Psychopharmacology (Berl) 2006;184:339-44. (Pubitemid 43255850)
    • (2006) Psychopharmacology , vol.184 , Issue.3-4 , pp. 339-344
    • Walters, C.L.1    Brown, S.2    Changeux, J.-P.3    Martin, B.4    Damaj, M.I.5
  • 41
    • 79960937851 scopus 로고    scopus 로고
    • Alpha 4{-beta}2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief
    • McGranahan TM, Patzlaff NE, Grady SR, Heinemann SF, Booker TK. {alpha}4{-beta}2 Nicotinic Acetylcholine Receptors on Dopaminergic Neurons Mediate Nicotine Reward and Anxiety Relief. J Neurosci 2011;31:10891-902.
    • (2011) J Neurosci , vol.31 , pp. 10891-10902
    • McGranahan, T.M.1    Patzlaff, N.E.2    Grady, S.R.3    Heinemann, S.F.4    Booker, T.K.5
  • 42
    • 79956016650 scopus 로고    scopus 로고
    • The necessity of alpha4 nicotinic receptors in nicotine-driven behaviors: Dissociation between reinforcing and motor effects of nicotine
    • Cahir E, Pillidge K, Drago J, Lawrence AJ. The necessity of alpha4 nicotinic receptors in nicotine-driven behaviors: dissociation between reinforcing and motor effects of nicotine. Neuropsychopharmacology 2011;36:1505-17.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1505-1517
    • Cahir, E.1    Pillidge, K.2    Drago, J.3    Lawrence, A.J.4
  • 44
    • 79953246461 scopus 로고    scopus 로고
    • Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake
    • Fowler CD, Lu Q, Johnson PM, Marks MJ, Kenny PJ. Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake. Nature 2011;471:597-601.
    • (2011) Nature , vol.471 , pp. 597-601
    • Fowler, C.D.1    Lu, Q.2    Johnson, P.M.3    Marks, M.J.4    Kenny, P.J.5
  • 46
    • 0021880586 scopus 로고
    • Relationship between nicotine-induced seizures and hippocampal nicotinic receptors
    • DOI 10.1016/0024-3205(85)90628-9
    • Miner LL, Marks MJ, Collins AC. Relationship between nicotine-induced seizures and hippocampal nicotinic receptors. Life Sci 1985;37:75-83. (Pubitemid 15039763)
    • (1985) Life Sciences , vol.37 , Issue.1 , pp. 75-83
    • Miner, L.L.1    Marks, M.J.2    Collins, A.C.3
  • 48
    • 0031936537 scopus 로고    scopus 로고
    • Sensitivity to the seizure-inducing effects of nicotine is associated with strain-specific variants of the α5 and α7 nicotinic receptor subunit genes
    • Stitzel JA, Blanchette JM, Collins AC. Sensitivity to the seizure-inducing effects of nicotine is associated with strain-specific variants of the alpha 5 and alpha 7 nicotinic receptor subunit genes. J Pharmacol Exp Ther 1998;284:1104-11. (Pubitemid 28130840)
    • (1998) Journal of Pharmacology and Experimental Therapeutics , vol.284 , Issue.3 , pp. 1104-1111
    • Stitzel, J.A.1    Blanchette, J.M.2    Collins, A.C.3
  • 49
    • 0037203840 scopus 로고    scopus 로고
    • Absence of α7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures
    • DOI 10.1016/S0169-328X(01)00309-6, PII S0169328X01003096
    • Franceschini D, Paylor R, Broide R, Salas R, Bassetto L, Gotti C, et al. Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures. Brain Res Mol Brain Res 2002;98:29-40. (Pubitemid 34142276)
    • (2002) Molecular Brain Research , vol.98 , Issue.1-2 , pp. 29-40
    • Franceschini, D.1    Paylor, R.2    Broide, R.3    Salas, R.4    Bassetto, L.5    Gotti, C.6    De Biasi, M.7
  • 50
    • 0036175413 scopus 로고    scopus 로고
    • Increased sensitivity to nicotine-induced seizures in mice expressing the L250t α7 nicotinic acetylcholine receptor mutation
    • DOI 10.1124/mol.61.3.695
    • Broide RS, Salas R, Ji D, Paylor R, Patrick JW, Dani JA, et al. Increased sensitivity to nicotine-induced seizures in mice expressing the L250T alpha 7 nicotinic acetylcholine receptor mutation. Mol Pharmacol 2002;61:695-705. (Pubitemid 34171936)
    • (2002) Molecular Pharmacology , vol.61 , Issue.3 , pp. 695-705
    • Broide, R.S.1    Salas, R.2    Ji, D.3    Paylor, R.4    Patrick, J.W.5    Dani, J.A.6    De Biasi, M.7
  • 52
    • 34548825644 scopus 로고    scopus 로고
    • Nicotineinduced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation
    • Teper Y, Whyte D, Cahir E, Lester HA, Grady SR, Marks MJ, et al. Nicotineinduced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation. J Neurosci 2007;27:10128-42.
    • (2007) J Neurosci , vol.27 , pp. 10128-11042
    • Teper, Y.1    Whyte, D.2    Cahir, E.3    Lester, H.A.4    Grady, S.R.5    Marks, M.J.6
  • 53
    • 80053132114 scopus 로고    scopus 로고
    • Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the beta2 nicotinic receptor
    • Xu J, Cohen BN, Zhu Y, Dziewczapolski G, Panda S, Lester HA, et al. Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the beta2 nicotinic receptor. Mol Psychiatry 2011;16:1048-61.
    • (2011) Mol Psychiatry , vol.16 , pp. 1048-1061
    • Xu, J.1    Cohen, B.N.2    Zhu, Y.3    Dziewczapolski, G.4    Panda, S.5    Lester, H.A.6
  • 54
    • 0037731430 scopus 로고    scopus 로고
    • The nicotinic acetylcholine receptor subunit α5 mediates short-term effects of nicotine in vivo
    • DOI 10.1124/mol.63.5.1059
    • Salas R, Orr-Urtreger A, Broide RS, Beaudet A, Paylor R, De Biasi M. The nicotinic acetylcholine receptor subunit alpha 5 mediates short-Term effects of nicotine in vivo. Mol Pharmacol 2003;63:1059-66. (Pubitemid 36529924)
    • (2003) Molecular Pharmacology , vol.63 , Issue.5 , pp. 1059-1066
    • Salas, R.1    Orr-Urtreger, A.2    Broide, R.S.3    Beaudet, A.4    Paylor, R.5    De Biasi, M.6
  • 55
    • 3242680723 scopus 로고    scopus 로고
    • The α3 and β4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice
    • DOI 10.1016/j.neuropharm.2004.05.002, PII S0028390804001352
    • Salas R, Cook KD, Bassetto L, De Biasi M. The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice. Neuropharmacology 2004;47:401-7. (Pubitemid 38953231)
    • (2004) Neuropharmacology , vol.47 , Issue.3 , pp. 401-407
    • Salas, R.1    Cook, K.D.2    Bassetto, L.3    De Biasi, M.4
  • 56
    • 0026664965 scopus 로고
    • Cholinergic gating of response to auditory stimuli in rat hippocampus
    • Luntz-Leybman V, Bickford PC, Freedman R. Cholinergic gating of response to auditory stimuli in rat hippocampus. Brain Res 1992;587:130-6.
    • (1992) Brain Res , vol.587 , pp. 130-136
    • Luntz-Leybman, V.1    Bickford, P.C.2    Freedman, R.3
  • 57
    • 0030222252 scopus 로고    scopus 로고
    • Genetic correlation of inhibitory gating of hippocampal auditory evoked response and α-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains
    • DOI 10.1016/0893-133X(95)00178-G
    • Stevens KE, Freedman R, Collins AC, Hall M, Leonard S, Marks MJ, et al. Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains. Neuropsychopharmacology 1996;15:152-62. (Pubitemid 26255162)
    • (1996) Neuropsychopharmacology , vol.15 , Issue.2 , pp. 152-162
    • Stevens, K.E.1    Freedman, R.2    Collins, A.C.3    Hall, M.4    Leonard, S.5    Marks, M.J.6    Rose, G.M.7
  • 58
    • 39149129049 scopus 로고    scopus 로고
    • Altered hippocampal circuit function in c3h alpha7 null mutant heterozygous mice
    • Adams CE, Yonchek JC, Zheng L, Collins AC, Stevens KE. Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice. Brain Res 2008;1194:138-45.
    • (2008) Brain Res , vol.1194 , pp. 138-145
    • Adams, C.E.1    Yonchek, J.C.2    Zheng, L.3    Collins, A.C.4    Stevens, K.E.5
  • 59
    • 0031596817 scopus 로고    scopus 로고
    • Selective alpha7-nicotinic agonists normalize inhibition of auditory response in dba mice
    • Stevens KE, Kem WR, Mahnir VM, Freedman R. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology (Berl) 1998;136:320-7.
    • (1998) Psychopharmacology (Berl , vol.136 , pp. 320-307
    • Stevens, K.E.1    Kem, W.R.2    Mahnir, V.M.3    Freedman, R.4
  • 60
    • 0020641301 scopus 로고
    • Nicotinic cholinergic receptor binding sites in the brain: Regulation in vivo
    • Schwartz RD, Kellar KJ. Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo. Science 1983;220:214-6. (Pubitemid 13115272)
    • (1983) Science , vol.220 , Issue.4593 , pp. 214-216
    • Schwartz, R.D.1    Kellar, K.J.2
  • 62
    • 0023950487 scopus 로고
    • Evidence that tobacco smoking increases the density of (-)-[3h]nicotine binding sites in human brain
    • Benwell ME, Balfour DJ, Anderson JM. Evidence that tobacco smoking increases the density of (-)-[3H]nicotine binding sites in human brain. J Neurochem 1988;50:1243-7.
    • (1988) J Neurochem , vol.50 , pp. 1243-1247
    • Benwell, M.E.1    Balfour, D.J.2    Anderson, J.M.3
  • 67
    • 0025840195 scopus 로고
    • Genotype influences the development of tolerance to nicotine in the mouse
    • Marks MJ, Campbell SM, Romm E, Collins AC. Genotype influences the development of tolerance to nicotine in the mouse. J Pharmacol Exp Ther 1991;259:392-402.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 392-402
    • Marks, M.J.1    Campbell, S.M.2    Romm, E.3    Collins, A.C.4
  • 68
    • 84881110933 scopus 로고    scopus 로고
    • Unraveling the neurobiology of nicotine dependence using genetically engineered mice
    • Epub ahead of print
    • Stoker AK, Markou A. Unraveling the neurobiology of nicotine dependence using genetically engineered mice. Curr Opin Neurobiol 2013. http://dx.doi.org/10.1016/j.conb.2013.02.013 [Epub ahead of print].
    • (2013) Curr Opin Neurobiol
    • Stoker, A.K.1    Markou, A.2
  • 69
    • 58149348655 scopus 로고    scopus 로고
    • Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: Evidence from genetically modified mice
    • Fowler CD, Arends MA, Kenny PJ. Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice. Behav Pharmacol 2008;19:461-84.
    • (2008) Behav Pharmacol , vol.19 , pp. 461-484
    • Fowler, C.D.1    Arends, M.A.2    Kenny, P.J.3
  • 70
    • 84862664017 scopus 로고    scopus 로고
    • Utility of genetically modified mice for understanding the neurobiology of substance use disorders
    • Fowler CD, Kenny PJ. Utility of genetically modified mice for understanding the neurobiology of substance use disorders. Hum Genet 2012;131:941-57.
    • (2012) Hum Genet , vol.131 , pp. 941-957
    • Fowler, C.D.1    Kenny, P.J.2
  • 71
    • 79951694140 scopus 로고    scopus 로고
    • Genetic vulnerability and susceptibility to substance dependence
    • Bierut LJ. Genetic vulnerability and susceptibility to substance dependence. Neuron 2011;69:618-27.
    • (2011) Neuron , vol.69 , pp. 618-627
    • Bierut, L.J.1
  • 72
    • 68249094627 scopus 로고    scopus 로고
    • The genetic components of alcohol and nicotine co-Addiction: From genes to behavior
    • Schlaepfer IR, Hoft NR, Ehringer MA. The genetic components of alcohol and nicotine co-Addiction: from genes to behavior. Curr Drug Abuse Rev 2008;1:124-34.
    • (2008) Curr Drug Abuse Rev , vol.1 , pp. 124-134
    • Schlaepfer, I.R.1    Hoft, N.R.2    Ehringer, M.A.3
  • 73
    • 47849083570 scopus 로고    scopus 로고
    • Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: Converging evidence from human and animal research
    • Portugal GS, Gould TJ. Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research. Behav Brain Res 2008;193:1-16.
    • (2008) Behav Brain Res , vol.193 , pp. 1-16
    • Portugal, G.S.1    Gould, T.J.2
  • 74
    • 0032565878 scopus 로고    scopus 로고
    • Nicotine metabolism defect reduces smoking [8]
    • DOI 10.1038/31623
    • Pianezza ML, Sellers EM, Tyndale RF. Nicotine metabolism defect reduces smoking. Nature 1998;393:750. (Pubitemid 28299478)
    • (1998) Nature , vol.393 , Issue.6687 , pp. 750
    • Pianezza, M.L.1    Sellers, E.M.2    Tyndale, R.F.3
  • 75
    • 43149086136 scopus 로고    scopus 로고
    • The multifaceted role of inhibition in epilepsy: Seizure-genesis through excessive GABAergic inhibition in autosomal dominant nocturnal frontal lobe epilepsy
    • DOI 10.1097/WCO.0b013e3282f52f5f, PII 0001905220080400000009
    • Mann EO, Mody I. The multifaceted role of inhibition in epilepsy: seizuregenesis through excessive GABAergic inhibition in autosomal dominant nocturnal frontal lobe epilepsy. Curr Opin Neurol 2008;21:155-60. (Pubitemid 351644156)
    • (2008) Current Opinion in Neurology , vol.21 , Issue.2 , pp. 155-160
    • Mann, E.O.1    Mody, I.2
  • 76
    • 84869837265 scopus 로고    scopus 로고
    • Nocturnal frontal lobe epilepsy and the acetylcholine receptor
    • Ferini-Strambi L, Sansoni V, Combi R. Nocturnal frontal lobe epilepsy and the acetylcholine receptor. Neurologist 2012;18:343-9.
    • (2012) Neurologist , vol.18 , pp. 343-349
    • Ferini-Strambi, L.1    Sansoni, V.2    Combi, R.3
  • 77
    • 77955090532 scopus 로고    scopus 로고
    • Nicotinic receptor channelopathies and epilepsy
    • Steinlein OK, Bertrand D. Nicotinic receptor channelopathies and epilepsy. Pflugers Arch 2010;460:495-503.
    • (2010) Pflugers Arch , vol.460 , pp. 495-503
    • Steinlein, O.K.1    Bertrand, D.2
  • 78
    • 78649529025 scopus 로고    scopus 로고
    • Animal models for autosomal dominant frontal lobe epilepsy: On the origin of seizures
    • Steinlein OK. Animal models for autosomal dominant frontal lobe epilepsy: on the origin of seizures. Expert Rev Neurother 2010;10:1859-67.
    • (2010) Expert Rev Neurother , vol.10 , pp. 1859-1867
    • Steinlein, O.K.1
  • 79
    • 36248947308 scopus 로고    scopus 로고
    • Nicotine responses in hypersensitive and knockout α4 mice account for tolerance to both hypothermia and locomotor suppression in wild-type mice
    • DOI 10.1152/physiolgenomics.00063.2007
    • Tapper AR, McKinney SL, Marks MJ, Lester HA. Nicotine responses in hypersensitive and knockout alpha 4 mice account for tolerance to both hypothermia and locomotor suppression in wild-Type mice. Physiol Genomics 2007; 31:422-8. (Pubitemid 350127782)
    • (2007) Physiological Genomics , vol.31 , Issue.3 , pp. 422-428
    • Tapper, A.R.1    McKinney, S.L.2    Marks, M.J.3    Lester, H.A.4
  • 82
    • 66649097962 scopus 로고    scopus 로고
    • Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (chrn) genes
    • Saccone NL, Saccone SF, Hinrichs AL, Stitzel JA, Duan W, Pergadia ML, et al. Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes. Am J Med Genet B Neuropsychiatr Genet 2009;150B:453-66.
    • (2009) Am J Med Genet B Neuropsychiatr Genet , vol.150 B , pp. 453-466
    • Saccone, N.L.1    Saccone, S.F.2    Hinrichs, A.L.3    Stitzel, J.A.4    Duan, W.5    Pergadia, M.L.6
  • 83
    • 73049084248 scopus 로고    scopus 로고
    • Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25
    • Bierut LJ. Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. Trends Pharmacol Sci 2010;31:46-51.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 46-51
    • Bierut, L.J.1
  • 85
    • 0036800871 scopus 로고    scopus 로고
    • Lack of cb1 cannabinoid receptors modifies nicotine behavioural responses, but not nicotine abstinence
    • Castane A, Valjent E, Ledent C, Parmentier M, Maldonado R, Valverde O. Lack of CB1 cannabinoid receptors modifies nicotine behavioural responses, but not nicotine abstinence. Neuropharmacology 2002;43:857-67.
    • (2002) Neuropharmacology , vol.43 , pp. 857-8567
    • Castane, A.1    Valjent, E.2    Ledent, C.3    Parmentier, M.4    Maldonado, R.5    Valverde, O.6
  • 86
    • 77649111219 scopus 로고    scopus 로고
    • Conditional knockout of nmda receptors in dopamine neurons prevents nicotine-conditioned place preference
    • Wang LP, Li F, Shen X, Tsien JZ. Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. PLoS ONE 2010;5:e8616.
    • (2010) PLoS ONE , vol.5
    • Wang, L.P.1    Li, F.2    Shen, X.3    Tsien, J.Z.4
  • 87
    • 13944270211 scopus 로고    scopus 로고
    • Nicotine-induced antinociception, rewarding effects, and physical dependence are decreased in mice lacking the preproenkephalin gene
    • DOI 10.1523/JNEUROSCI.3008-04.2005
    • Berrendero F, Mendizabal V, Robledo P, Galeote L, Bilkei-Gorzo A, Zimmer A, et al. Nicotine-induced antinociception, rewarding effects, and physical dependence are decreased in mice lacking the preproenkephalin gene. J Neurosci 2005;25:1103-12. (Pubitemid 40268951)
    • (2005) Journal of Neuroscience , vol.25 , Issue.5 , pp. 1103-1112
    • Berrendero, F.1    Mendizabal, V.2    Robledo, P.3    Galeote, L.4    Bilkei-Gorzo, A.5    Zimmer, A.6    Maldonado, R.7
  • 89
    • 78651249190 scopus 로고    scopus 로고
    • Mice lacking the galanin gene show decreased sensitivity to nicotine conditioned place preference
    • Neugebauer NM, Henehan RM, Hales CA, Picciotto MR. Mice lacking the galanin gene show decreased sensitivity to nicotine conditioned place preference. Pharmacol Biochem Behav 2011;98:87-93.
    • (2011) Pharmacol Biochem Behav , vol.98 , pp. 87-93
    • Neugebauer, N.M.1    Henehan, R.M.2    Hales, C.A.3    Picciotto, M.R.4
  • 90
    • 80053148608 scopus 로고    scopus 로고
    • Protein kinase c epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens
    • Lee AM, Messing RO. Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens. Proc Natl Acad Sci U S A 2011;108:16080-85.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 16080-16085
    • Lee, A.M.1    Messing, R.O.2
  • 91
    • 67449168412 scopus 로고    scopus 로고
    • Nucleus accumbens creb activity is necessary for nicotine conditioned place preference
    • Brunzell DH, Mineur YS, Neve RL, Picciotto MR. Nucleus accumbens CREB activity is necessary for nicotine conditioned place preference. Neuropsychopharmacology 2009;34:1993-2001.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1993-12001
    • Brunzell, D.H.1    Mineur, Y.S.2    Neve, R.L.3    Picciotto, M.R.4
  • 92
    • 33845961954 scopus 로고    scopus 로고
    • Nicotinic receptors modulate transmitter cross talk in the CNS: Nicotinic modulation of transmitters
    • DOI 10.1385/JMN:30:1:137, PII JMN301137
    • Wonnacott S, Barik J, Dickinson J, Jones IW. Nicotinic receptors modulate transmitter cross talk in the CNS: nicotinic modulation of transmitters. J Mol Neurosci 2006;30:137-40. (Pubitemid 46035352)
    • (2006) Journal of Molecular Neuroscience , vol.30 , Issue.1-2 , pp. 137-140
    • Wonnacott, S.1    Barik, J.2    Dickinson, J.3    Jones, I.W.4
  • 93
    • 63849207572 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of action of nicotine in the cns
    • Barik J, Wonnacott S. Molecular and cellular mechanisms of action of nicotine in the CNS. Handb Exp Pharmacol 2009;173-207.
    • (2009) Handb Exp Pharmacol , pp. 173-207
    • Barik, J.1    Wonnacott, S.2
  • 94
    • 0023697461 scopus 로고
    • Adrenocortical hormone regulation of nicotine sensitivity in mice
    • Pauly JR, Ullman EA, Collins AC. Adrenocortical hormone regulation of nicotine sensitivity in mice. Physiol Behav 1988;44:109-16.
    • (1988) Physiol Behav , vol.44 , pp. 109-116
    • Pauly, J.R.1    Ullman, E.A.2    Collins, A.C.3
  • 95
    • 0024474491 scopus 로고
    • Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat
    • Wada E, Wada K, Boulter J, Deneris E, Heinemann S, Patrick J, et al. Distribution of alpha 2, alpha 3, alpha 4, and beta 2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat. J Comp Neurol 1989;284:314-35. (Pubitemid 19185398)
    • (1989) Journal of Comparative Neurology , vol.284 , Issue.2 , pp. 314-335
    • Wada, E.1    Wada, K.2    Boulter, J.3    Deneris, E.4    Heinemann, S.5    Patrick, J.6    Swanson, L.W.7
  • 96
    • 0023447276 scopus 로고
    • Functional expression of two neuronal nicotinic acetylcholine receptors from cdna clones identifies a gene family
    • Boulter J, Connolly J, Deneris E, Goldman D, Heinemann S, Patrick J. Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family. Proc Natl Acad Sci U S A 1987;84: 7763-7.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 7763-7767
    • Boulter, J.1    Connolly, J.2    Deneris, E.3    Goldman, D.4    Heinemann, S.5    Patrick, J.6
  • 97
    • 0034732231 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function
    • DOI 10.1016/S0014-2999(00)00007-8, PII S0014299900000078
    • Marubio LM, Changeux J. Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function. Eur J Pharmacol 2000;393: 113-21. (Pubitemid 30193407)
    • (2000) European Journal of Pharmacology , vol.393 , Issue.1-3 , pp. 113-121
    • Marubio, L.M.1    Changeux, J.-P.2
  • 98
    • 11944260284 scopus 로고
    • Alpha 3, alpha 5, and beta 4: Three members of the rat neuronal nicotinic acetylcholine receptor-related gene family form a gene cluster
    • Boulter J, O'Shea-Greenfield A, Duvoisin RM, Connolly JG, Wada E, Jensen A, et al. Alpha 3, alpha 5, and beta 4: three members of the rat neuronal nicotinic acetylcholine receptor-related gene family form a gene cluster. J Biol Chem 1990;265:4472-82.
    • (1990) J Biol Chem , vol.265 , pp. 4472-4482
    • Boulter, J.1    O'Shea-Greenfield, A.2    Duvoisin, R.M.3    Connolly, J.G.4    Wada, E.5    Jensen, A.6
  • 99
    • 0027518923 scopus 로고
    • 7: A nicotinic cation channel highly permeable to calcium
    • Seguela P, Wadiche J, Dineley-Miller K, Dani JA, Patrick JW. Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium. J Neurosci 1993;13:596-604. (Pubitemid 23045143)
    • (1993) Journal of Neuroscience , vol.13 , Issue.2 , pp. 596-604
    • Seguela, P.1    Wadiche, J.2    Dineley-Miller, K.3    Dani, J.A.4    Patrick, J.W.5
  • 100
    • 0033587809 scopus 로고    scopus 로고
    • Involvement of α6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion
    • le Novere N, Zoli M, Lena C, Ferrari R, Picciotto MR, Merlo-Pich E, et al. Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion. Neuroreport 1999;10:2497-501. (Pubitemid 29418126)
    • (1999) NeuroReport , vol.10 , Issue.12 , pp. 2497-2501
    • Le Novere, N.1    Zoli, M.2    Lena, C.3    Ferrari, R.4    Picciotto, M.R.5    Merlo-Pich, E.6    Cnangeux, J.-P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.