Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive α4 nicotinic receptors

Journal of Neuroscience

Volumn 23, Issue 7, 2003, Pages 2582-2590

  Fonck, Carlos ^a   Nashmi, Raad ^a   Deshpande, Purnima ^a   Damaj, M Imad ^b   Marks, Michael J ^c   Riedel, Anett ^d   Schwarz, Johannes ^a,d   Collins, Allan C ^c   Labarca, Cesar ^a   Lester, Henry A ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

ADNFLE; Cholinergic; Epilepsy; Gain of function; Knock in; Mouse; Nicotinic receptor; Seizure

Indexed keywords

ALPHA4 NICOTINIC RECEPTOR; BICUCULLINE; EPIBATIDINE; GALANTAMINE; MORPHINE; NALOXONE; NEOMYCIN; NICOTINE; NICOTINIC RECEPTOR; TACRINE; UNCLASSIFIED DRUG;

ALLELE; AMINO ACID SUBSTITUTION; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BRAIN MEMBRANE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; DRUG SENSITIVITY; ELECTROENCEPHALOGRAM; ELECTROPHYSIOLOGY; EPILEPSY; FRONTAL LOBE EPILEPSY; GENE CASSETTE; GENE DOSAGE; INTRON; KNOCK IN MOUSE; MOUSE; MOUSE STRAIN; NEUROANATOMY; NONHUMAN; PRIORITY JOURNAL; SEIZURE; STRAIN DIFFERENCE; THETA RHYTHM;

EID: 0037388806     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-07-02582.2003     Document Type: Article

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