The multifaceted role of inhibition in epilepsy: Seizure-genesis through excessive GABAergic inhibition in autosomal dominant nocturnal frontal lobe epilepsy

Current Opinion in Neurology

Volumn 21, Issue 2, 2008, Pages 155-160

  Mann, Edward O ^a   Mody, Istvan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Autosomal dominant nocturnal frontal lobe epilepsy; GABA; Inhibition; Interneurons; Nicotinic acetylcholine receptors; Synchronization

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; CANNABINOID; CANNABIS; CHOLECYSTOKININ; NICOTINE; NICOTINIC RECEPTOR; PICROTOXIN;

ALLELE; ALPHA CHAIN; AUTOSOMAL DOMINANT DISORDER; DRUG EFFECT; ELECTROENCEPHALOGRAM; EPILEPSY; EPILEPTOGENESIS; FRONTAL LOBE EPILEPSY; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; GENE FUNCTION; GENE MUTATION; HUMAN; IN VIVO CULTURE; INTERNEURON; MOUSE STRAIN; NEOCORTEX; NONHUMAN; PYRAMIDAL NERVE CELL; REVIEW; SEIZURE; TRANSGENIC MOUSE;

ANIMALS; CHROMOSOME DISORDERS; CHRONOBIOLOGY DISORDERS; DISEASE MODELS, ANIMAL; EPILEPSY, FRONTAL LOBE; FRONTAL LOBE; GAMMA-AMINOBUTYRIC ACID; GENES, DOMINANT; HUMANS; MICE; NEURAL INHIBITION; RECEPTORS, NICOTINIC;

EID: 43149086136     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/WCO.0b013e3282f52f5f     Document Type: Review

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