Tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1841, Issue 1, 2014, Pages 22-33

  Li, Songtao ^a,b   Li, Jiaxin ^a   Shen, Chen ^a   Zhang, Ximei ^a   Sun, Shan ^c   Cho, Michael ^c   Sun, Changhao ^b   Song, Zhenyuan ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c University of Illinois at Chicago   (United States)

Author keywords

AMPK; Autophagy; Lipotoxicity; Nrf2; SFAs; tert Butylhydroquinone

Indexed keywords

GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIVER PROTECTIVE AGENT; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PALMITIC ACID; PROTEIN IRE1; PROTEIN KINASE B; SMALL INTERFERING RNA; STEARIC ACID; TERT BUTYLHYDROQUINONE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; ENDOPLASMIC RETICULUM STRESS; FLUORESCENCE MICROSCOPY; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIGHT CHAIN; LIPOTOXICITY; LIVER CELL; LIVER CELL CARCINOMA; LIVER CELL CULTURE; LIVER PROTECTION; LIVER TOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 84885504929     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2013.09.004     Document Type: Article

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