HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium

Journal of Immunology

Volumn 191, Issue 8, 2013, Pages 4246-4258

  Nazli, Aisha ^a,b   Kafka, Jessica K ^a,b   Ferreira, Victor H ^a,b   Anipindi, Varun ^a,b   Mueller, Kristen ^a,b   Osborne, Brendan J ^c   Dizzell, Sara ^a,b   Chauvin, Sarah ^a,b   Mian, M Firoz ^a,b   Ouellet, Michel ^d   Tremblay, Michel J ^d   Mossman, Karen L ^a,b   Ashkar, Ali A ^a,b   Kovacs, Colin ^e   Bowdish, Dawn M E ^a,b   Snider, Denis P ^a,b   Kaul, Rupert ^c   Kaushic, Charu ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITÉ LAVAL   (Canada)

^e Canadian Immunodeficiency Collaborative   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 120; HEPARAN SULFATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ADULT; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN TISSUE; IMMUNOMODULATION; INNATE IMMUNITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TIGHT JUNCTION; VIRUS TRANSMISSION;

ADULT; CELL LINE; CYTOKINES; ENZYME ACTIVATION; EPITHELIUM; FEMALE; GENITALIA, FEMALE; HEK293 CELLS; HEPARITIN SULFATE; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HIV-1; HUMANS; IMMUNITY, INNATE; MALE; MIDDLE AGED; MUCOUS MEMBRANE; NF-KAPPA B; PROTEIN BINDING; SEMEN; SIGNAL TRANSDUCTION; TIGHT JUNCTIONS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 84885455013     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1301482     Document Type: Article

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