HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA)

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Hioe, Catarina E ^a   Tuen, Michael ^a   Vasiliver Shamis, Gaia ^a   Alvarez, Yelina ^a   Prins, Kathleen C ^a   Banerjee, Sagarika ^a   Nádas, Arthur ^a   Cho, Michael W ^b   Dustin, Michael L ^a   Kachlany, Scott C ^c,d  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b IOWA STATE UNIVERSITY   (United States)

^c RUTGERS SCHOOL OF DENTAL MEDICINE   (United States)

^d Actinobac Biomed Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; GLYCOPROTEIN GP 120; INTERCELLULAR ADHESION MOLECULE 1; LEUKOTOXIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; VIRUS DNA; ACTIN; EXOTOXIN;

ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CELL INTERACTION; CELL KILLING; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG TARGETING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; LIGAND BINDING; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TARGET CELL; VIRUS CELL INTERACTION; VIRUS INHIBITION; VIRUS LOAD; VIRUS TRANSMISSION; VIRUS VIRULENCE; CELL CULTURE; CELL SURVIVAL; DRUG EFFECT; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION;

BACTERIA (MICROORGANISMS); HUMAN IMMUNODEFICIENCY VIRUS 1;

ACTINS; CD4-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; CELLS, CULTURED; EXOTOXINS; FLOW CYTOMETRY; HIV ENVELOPE PROTEIN GP120; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MICROSCOPY, FLUORESCENCE; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 79961155416     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023202     Document Type: Article

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