Transcriptomic and epigenetic changes in early liver steatosis associated to obesity: Effect of dietary methyl donor supplementation

Molecular Genetics and Metabolism

Volumn 110, Issue 3, 2013, Pages 388-395

  Cordero, Paul ^a   Campion, Javier ^a,b   Milagro, Fermin I ^a,b   Martinez, J Alfredo ^a,b  

^a UNIVERSITY OF NAVARRA   (Spain)

^b Instituto de Salud Carlos III   (Spain)

Author keywords

DNA methylation; Fatty liver; Gene expression; High fat sucrose diet; Methyl donor supplementation; Obesity

Indexed keywords

BETAINE; CHOLINE; CYANOCOBALAMIN; FOLIC ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; SUCROSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; DNA METHYLATION; EPIGENETICS; FAT CONTENT; FATTY LIVER; LIPID METABOLISM; LIPID STORAGE; LIVER WEIGHT; MALE; METHYL DONOR SUPPLEMENTATION; MICROARRAY ANALYSIS; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; THERAPY EFFECT; TRANSCRIPTOMICS;

ANIMALIA; RATTUS NORVEGICUS;

ALANINE TRANSAMINASE; ALT; ANALYSIS OF VARIANCE; ANOVA; APPLIED PHARMACOBIOLOGY CENTER; ASPARTATE TRANSAMINASE; AST; BENJAMINI-HOCHBERG FALSE DISCOVERY RATE; CIFA; DNA METHYLATION; FATTY LIVER; FDR-BH; FFA; FREE FATTY ACIDS; GENE EXPRESSION; HFS; HIGH-FAT SUCROSE DIET; HIGH-FAT-SUCROSE; METHYL DONOR SUPPLEMENTATION; NAFDL; NASH; NON-ALCOHOLIC FATTY LIVER DISEASE; NON-ALCOHOLIC STEATOHEPATITIS; OBESITY; REAL TIME POLYMERASE CHAIN REACTION; RMA; ROBUST MULTICHIP AVERAGE; RT-QPCR;

ANIMALS; BASE SEQUENCE; BIOLOGICAL MARKERS; BODY WEIGHT; CPG ISLANDS; DIETARY SUPPLEMENTS; DNA METHYLATION; EPIGENESIS, GENETIC; FATTY LIVER; GENE EXPRESSION REGULATION; GENE ORDER; LIVER; MALE; MOLECULAR SEQUENCE DATA; OBESITY; RATS; TRANSCRIPTOME;

EID: 84885431822     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2013.08.022     Document Type: Article

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